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The map label for this gene is uvrD [C]

Identifier: 62389624

GI number: 62389624

Start: 762376

End: 764676

Strand: Reverse

Name: uvrD [C]

Synonym: cg0842

Alternate gene names: 62389624

Gene position: 764676-762376 (Counterclockwise)

Preceding gene: 62389625

Following gene: 62389623

Centisome position: 23.29

GC content: 55.54

Gene sequence:

>2301_bases
ATGGTTTCTTATAGCGTGCACGGCGCACTAGATATCGACGGCAGCCTCAAAAAACTCACCCTCGATTTCCTCAATAAACT
AGCCACCAATCCAGCTTCCCCGGGGCTTCATATTGAGCCCATCAAAAACAGCATCGACTCCCGCGTCCGCACAGGTCGGG
TCAATGATCAATTCCGCGCAGTGCTTTTTGAGCTTCACGACGAATTTGATCATCACTTTGTAGTGGTTGGTGTTTATCCC
CATGATGATGCCATCACCAAGGCAGGAAAAATCCGCCTTGAAGTCAACTCTGTTAACGGCATTACTCGACTCATCGAGGA
AACTACCGTTCCTGCGCAAAAAGACGATCAGGAATCTCGTCGCAAAGCGGAAGAGGCCGCAAAGCGGGCGGAGGAGCAAC
TCCGGGACGCCGTCGAAGTACCCACCCCAGTGGAGCTGCCCAGCCCTGGTGAGGCGCTCGCACATGCAGGGCACACCCCA
GAAGTCCTGGAAGCCGAGCTCGGCATTGACCCGGCTGCCACCCGTATTGTGTTGGAACTTGCCTCAGAGGATGACATCGC
AGCAGCGCTTCCTAGCAGCCCGACGTGGGAAAAAGACGCACTTATCGGCCTTGTCGCCGGTTTGAGCATTGAAGATATCC
GCGAATCGCTCGCTATCCCCGCACCTTCCACAGAGCCGGATACCCGCAGCGAAGATACCAGGCTCATTGCTGGGCTTAAA
ACCCCAGCAGCGCAAATGGACTTTGCCTATTTGGATACCCCAAATAGCAATGACCTGCGCCGCGTTATTGAAACTGAAGG
TTTTGATAGCTGGCGCGTGTATATCGACCCCAGCCAGCGCTCCTTAGTCACCCGCAACTTCAGCGGATCGGGTCGCGTTT
TTGGTGGAGCTGGCACCGGCAAAACCGTGGTGGTAGTCCACCGTGCCAACCGCCTGGTCACTTCTGATGGACACCTTGAG
ACCGACGATAAGACGCCTCGAGTCCTGCTCACCACCTATACCCGCGGTTTGGCCGATGCGTTGAAATCCTCCATGAACGC
GCTTAATCCCACTTTCCCCGAGGCAGAAAAACCCGGTAGTCCTGGCTTGTGGATCAGCGGAATTGATGCCTTGGCAAATA
AGGTGGTTGCGCTAGCAAACACCGCCGAACGTGAGGCAGCAACCACTGCTATCTTGGGGCGTGCAGCCGGCAGAATCACC
CCATTCATCGGCAACGGCGAACAAGAATTTTGGATCGACGCGATCATTTCCGCAGATCCCGGCGATCTATCAGAAGAAAT
CAGCAATACTGAATTCCTCGCCCAAGAGTTTGAAACCGTAATCCTAGCCCGCGGAATCACCCAAGAAAAGGACTATCTGC
GTGCACCTCGTCCCGGCCGTGGTACCCCACTAAACCGCGTACAACGCAAAAAAGTGTGGGCGATTATTCAGCAATTCATG
ACTTCCTGTGCGCGCGAAGGAAAGATGTCCTGGCCAGCGCTTTCCTCCATCGCCGCAAACATCCTGGAGCAGCGCGCCGC
CGCCGGCCAGGGCCGGCTATTTGACCATGTGCTTATCGACGAGGCCCAGGACTTCCACGCCGGACATTGGCTCTTACTCA
GGGCTGCGGTAGCCGAAGGTCCCAATGACATCTTCTTGGCTGAGGATTCACACCAGCGCATCTACGGCCAACATCATGTG
CTAAGCCGTTTTGGTATTTCCACCCGCGGTCGGGCGTCTAAGCGACTCACCCTTAACTACCGCACCACCGCCGAAAACCT
CAGTTACGCACTTGGCATGCTCACCGGTGAATGGACCGACGCCGAAGGCGAAACGGACACAATTGAGCACTATCGCTCAG
CGCGTAAGGGCCCCAAGCCACACCTCTACCAATTTGAATCTGAGACCGACGAGTTCGAAGCAATCGCTGAGCTCATCAAG
GTGTGGCAGGACAGGACCACCGATGTACGCATCGGCATTTTGGCACGCACCCGTCCTTTGATCAACCGCGTGGTTAATGC
GCTCTCTGAGCAGGGCATCGATGCCGTCAAGACGCAAAATGCCGAACTTGCAGCCCACGAAACTGTCAGTGTAATGACAA
TGCACGGAGCTAAAGGCATGGAGTTTACCCATGTCATCTTGATCGGAATGGGCCGTGACCTCATTCCTTTGCAATACACC
ATGCAAGGTTTAGGCGAGGCCGAGCGTAACGACGCCCAACAGCGCGAACGCTCCTTGCTCTACGTTGCAGCTTCTCGTGC
ACGTGATGCCCTTGTTCTCACCACGCATACTGAGCCTTCGGAGTTGCTGCCGCGGGTTTAG

Upstream 100 bases:

>100_bases
TGAAGGTTGGACGCTGCTTTTTGCAAATGACCTCGAGACCTCCGATATTCCCGCTGCCCTTCGTCCCTAGTACACCCAAA
GTTTATGAAAGATAAAAATC

Downstream 100 bases:

>100_bases
AGCACCAAGTAACTAAAGTTCGAAAGTATTTCCGAACGGTGTCGGCCTCTGCGCATACACTGTATTTTTAAAGAAAATTC
TTCTCAATTCTAAGGGTGAA

Product: DNA helicase

Products: NA

Alternate protein names: DNA Helicase; LexA Repressor; DNA Helicase II; UvrD/Rep Helicase; NERD Domain-Containing Protein; Superfamily I DNA/RNA Helicase; Helicase; Plasmid Stabilization System; Superfamily I DNA/RNA Helicase-Like Protein; UvrD/REP Helicase Domain Protein; NERD Domain Protein; Superfamily I DNA And RNA Helicase; Superfamily Protein I DNA/RNA Helicase; Peptidase; Superfamily I DNA And RNA Helicase-Like Protein; UvrD/REP Type DNA Helicase; UvrD/REP Family ATP-Dependent DNA Helicase; Uvrd/Rep Helicase; Helicase Protein; NA Helicase.; DNA Helicase II-Like Protein; DNA/RNA Helicase Superfamily I

Number of amino acids: Translated: 766; Mature: 766

Protein sequence:

>766_residues
MVSYSVHGALDIDGSLKKLTLDFLNKLATNPASPGLHIEPIKNSIDSRVRTGRVNDQFRAVLFELHDEFDHHFVVVGVYP
HDDAITKAGKIRLEVNSVNGITRLIEETTVPAQKDDQESRRKAEEAAKRAEEQLRDAVEVPTPVELPSPGEALAHAGHTP
EVLEAELGIDPAATRIVLELASEDDIAAALPSSPTWEKDALIGLVAGLSIEDIRESLAIPAPSTEPDTRSEDTRLIAGLK
TPAAQMDFAYLDTPNSNDLRRVIETEGFDSWRVYIDPSQRSLVTRNFSGSGRVFGGAGTGKTVVVVHRANRLVTSDGHLE
TDDKTPRVLLTTYTRGLADALKSSMNALNPTFPEAEKPGSPGLWISGIDALANKVVALANTAEREAATTAILGRAAGRIT
PFIGNGEQEFWIDAIISADPGDLSEEISNTEFLAQEFETVILARGITQEKDYLRAPRPGRGTPLNRVQRKKVWAIIQQFM
TSCAREGKMSWPALSSIAANILEQRAAAGQGRLFDHVLIDEAQDFHAGHWLLLRAAVAEGPNDIFLAEDSHQRIYGQHHV
LSRFGISTRGRASKRLTLNYRTTAENLSYALGMLTGEWTDAEGETDTIEHYRSARKGPKPHLYQFESETDEFEAIAELIK
VWQDRTTDVRIGILARTRPLINRVVNALSEQGIDAVKTQNAELAAHETVSVMTMHGAKGMEFTHVILIGMGRDLIPLQYT
MQGLGEAERNDAQQRERSLLYVAASRARDALVLTTHTEPSELLPRV

Sequences:

>Translated_766_residues
MVSYSVHGALDIDGSLKKLTLDFLNKLATNPASPGLHIEPIKNSIDSRVRTGRVNDQFRAVLFELHDEFDHHFVVVGVYP
HDDAITKAGKIRLEVNSVNGITRLIEETTVPAQKDDQESRRKAEEAAKRAEEQLRDAVEVPTPVELPSPGEALAHAGHTP
EVLEAELGIDPAATRIVLELASEDDIAAALPSSPTWEKDALIGLVAGLSIEDIRESLAIPAPSTEPDTRSEDTRLIAGLK
TPAAQMDFAYLDTPNSNDLRRVIETEGFDSWRVYIDPSQRSLVTRNFSGSGRVFGGAGTGKTVVVVHRANRLVTSDGHLE
TDDKTPRVLLTTYTRGLADALKSSMNALNPTFPEAEKPGSPGLWISGIDALANKVVALANTAEREAATTAILGRAAGRIT
PFIGNGEQEFWIDAIISADPGDLSEEISNTEFLAQEFETVILARGITQEKDYLRAPRPGRGTPLNRVQRKKVWAIIQQFM
TSCAREGKMSWPALSSIAANILEQRAAAGQGRLFDHVLIDEAQDFHAGHWLLLRAAVAEGPNDIFLAEDSHQRIYGQHHV
LSRFGISTRGRASKRLTLNYRTTAENLSYALGMLTGEWTDAEGETDTIEHYRSARKGPKPHLYQFESETDEFEAIAELIK
VWQDRTTDVRIGILARTRPLINRVVNALSEQGIDAVKTQNAELAAHETVSVMTMHGAKGMEFTHVILIGMGRDLIPLQYT
MQGLGEAERNDAQQRERSLLYVAASRARDALVLTTHTEPSELLPRV
>Mature_766_residues
MVSYSVHGALDIDGSLKKLTLDFLNKLATNPASPGLHIEPIKNSIDSRVRTGRVNDQFRAVLFELHDEFDHHFVVVGVYP
HDDAITKAGKIRLEVNSVNGITRLIEETTVPAQKDDQESRRKAEEAAKRAEEQLRDAVEVPTPVELPSPGEALAHAGHTP
EVLEAELGIDPAATRIVLELASEDDIAAALPSSPTWEKDALIGLVAGLSIEDIRESLAIPAPSTEPDTRSEDTRLIAGLK
TPAAQMDFAYLDTPNSNDLRRVIETEGFDSWRVYIDPSQRSLVTRNFSGSGRVFGGAGTGKTVVVVHRANRLVTSDGHLE
TDDKTPRVLLTTYTRGLADALKSSMNALNPTFPEAEKPGSPGLWISGIDALANKVVALANTAEREAATTAILGRAAGRIT
PFIGNGEQEFWIDAIISADPGDLSEEISNTEFLAQEFETVILARGITQEKDYLRAPRPGRGTPLNRVQRKKVWAIIQQFM
TSCAREGKMSWPALSSIAANILEQRAAAGQGRLFDHVLIDEAQDFHAGHWLLLRAAVAEGPNDIFLAEDSHQRIYGQHHV
LSRFGISTRGRASKRLTLNYRTTAENLSYALGMLTGEWTDAEGETDTIEHYRSARKGPKPHLYQFESETDEFEAIAELIK
VWQDRTTDVRIGILARTRPLINRVVNALSEQGIDAVKTQNAELAAHETVSVMTMHGAKGMEFTHVILIGMGRDLIPLQYT
MQGLGEAERNDAQQRERSLLYVAASRARDALVLTTHTEPSELLPRV

Specific function: Has Both Atpase And Helicase Activities. Unwinds DNA Duplexes With 3' To 5' Polarity With Respect To The Bound Strand And Initiates Unwinding Most Effectively When A Single-Stranded Region Is Present. Involved In The Post-Incision Events Of Nucleotide Exc

COG id: COG0210

COG function: function code L; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 3000 [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.- [C]

Molecular weight: Translated: 84130; Mature: 84130

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSYSVHGALDIDGSLKKLTLDFLNKLATNPASPGLHIEPIKNSIDSRVRTGRVNDQFRA
CCEEEECEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCCCHHHHH
VLFELHDEFDHHFVVVGVYPHDDAITKAGKIRLEVNSVNGITRLIEETTVPAQKDDQESR
HHHHHHHCCCCEEEEEEEECCCHHHCCCCEEEEEEECCHHHHHHHHHHCCCCCCCCHHHH
RKAEEAAKRAEEQLRDAVEVPTPVELPSPGEALAHAGHTPEVLEAELGIDPAATRIVLEL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHHHHCCCCHHHHEEEEEE
ASEDDIAAALPSSPTWEKDALIGLVAGLSIEDIRESLAIPAPSTEPDTRSEDTRLIAGLK
CCCCCCEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECC
TPAAQMDFAYLDTPNSNDLRRVIETEGFDSWRVYIDPSQRSLVTRNFSGSGRVFGGAGTG
CCHHHCCEEEECCCCCHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCCCCCEEECCCCC
KTVVVVHRANRLVTSDGHLETDDKTPRVLLTTYTRGLADALKSSMNALNPTFPEAEKPGS
CEEEEEEECCEEEECCCCEECCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PGLWISGIDALANKVVALANTAEREAATTAILGRAAGRITPFIGNGEQEFWIDAIISADP
CCCEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEECCCCCEEEEEEEECCCC
GDLSEEISNTEFLAQEFETVILARGITQEKDYLRAPRPGRGTPLNRVQRKKVWAIIQQFM
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
TSCAREGKMSWPALSSIAANILEQRAAAGQGRLFDHVLIDEAQDFHAGHWLLLRAAVAEG
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCC
PNDIFLAEDSHQRIYGQHHVLSRFGISTRGRASKRLTLNYRTTAENLSYALGMLTGEWTD
CCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCC
AEGETDTIEHYRSARKGPKPHLYQFESETDEFEAIAELIKVWQDRTTDVRIGILARTRPL
CCCCHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHH
INRVVNALSEQGIDAVKTQNAELAAHETVSVMTMHGAKGMEFTHVILIGMGRDLIPLQYT
HHHHHHHHHHCCCHHHHCCCCCEEHHCEEEEEEECCCCCCCEEEEEEEECCCCCCHHHHH
MQGLGEAERNDAQQRERSLLYVAASRARDALVLTTHTEPSELLPRV
HHHCCCHHHHHHHHHHHHEEEEEECCCCCEEEEEECCCHHHHCCCC
>Mature Secondary Structure
MVSYSVHGALDIDGSLKKLTLDFLNKLATNPASPGLHIEPIKNSIDSRVRTGRVNDQFRA
CCEEEECEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCCCHHHHH
VLFELHDEFDHHFVVVGVYPHDDAITKAGKIRLEVNSVNGITRLIEETTVPAQKDDQESR
HHHHHHHCCCCEEEEEEEECCCHHHCCCCEEEEEEECCHHHHHHHHHHCCCCCCCCHHHH
RKAEEAAKRAEEQLRDAVEVPTPVELPSPGEALAHAGHTPEVLEAELGIDPAATRIVLEL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHHHHCCCCHHHHEEEEEE
ASEDDIAAALPSSPTWEKDALIGLVAGLSIEDIRESLAIPAPSTEPDTRSEDTRLIAGLK
CCCCCCEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECC
TPAAQMDFAYLDTPNSNDLRRVIETEGFDSWRVYIDPSQRSLVTRNFSGSGRVFGGAGTG
CCHHHCCEEEECCCCCHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCCCCCEEECCCCC
KTVVVVHRANRLVTSDGHLETDDKTPRVLLTTYTRGLADALKSSMNALNPTFPEAEKPGS
CEEEEEEECCEEEECCCCEECCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PGLWISGIDALANKVVALANTAEREAATTAILGRAAGRITPFIGNGEQEFWIDAIISADP
CCCEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEECCCCCEEEEEEEECCCC
GDLSEEISNTEFLAQEFETVILARGITQEKDYLRAPRPGRGTPLNRVQRKKVWAIIQQFM
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
TSCAREGKMSWPALSSIAANILEQRAAAGQGRLFDHVLIDEAQDFHAGHWLLLRAAVAEG
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCC
PNDIFLAEDSHQRIYGQHHVLSRFGISTRGRASKRLTLNYRTTAENLSYALGMLTGEWTD
CCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCC
AEGETDTIEHYRSARKGPKPHLYQFESETDEFEAIAELIKVWQDRTTDVRIGILARTRPL
CCCCHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHH
INRVVNALSEQGIDAVKTQNAELAAHETVSVMTMHGAKGMEFTHVILIGMGRDLIPLQYT
HHHHHHHHHHCCCHHHHCCCCCEEHHCEEEEEEECCCCCCCEEEEEEEECCCCCCHHHHH
MQGLGEAERNDAQQRERSLLYVAASRARDALVLTTHTEPSELLPRV
HHHCCCHHHHHHHHHHHHEEEEEECCCCCEEEEEECCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA