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The map label for this gene is yfhA [H]

Identifier: 62389556

GI number: 62389556

Start: 683316

End: 684344

Strand: Reverse

Name: yfhA [H]

Synonym: cg0769

Alternate gene names: 62389556

Gene position: 684344-683316 (Counterclockwise)

Preceding gene: 62389557

Following gene: 62389555

Centisome position: 20.85

GC content: 57.34

Gene sequence:

>1029_bases
ATGAGCCTTAGCCATCAACTCAAGCGCCAGCGCGCATCGCGCAACTCCCGCAGGTGGCTGATTGTTGCGGCATTGGGCGT
CGTCACGCTTGGTATTTTTGCTTTTTCTTTGATGTGGGGCGAGGTGTTTTATGGCCCTGCTCAGGTGCTGAAAGTGTTGT
CTGGACAGCAGGTTCCCGGCGCGAGTTATTCCGTTGGCGTGTTGCGTTTGCCGCGCGCGGTGATGGGTTTGACTGCGGGT
TTGGCGTTTGGCGCGGCGGGCGTGATTTTTCAGACGGTGTTGCGTAATCAGTTGGCGTCGCCGGATATTATCGGCATTTC
TTCTGGCGCGTCGGCGGCGGGCGTAATTTGCATTGTGTTTTTCGGGATGTCGCAGTCTGCAGTGTCGGCGATTTCTTTGT
GTGCGTCCTTGGCTGTGGCGTTGTTGATTTATCTGGTGGCGTATCGCGGTGGTTTTTCGGCCACGCGTCTGATTCTTACC
GGCATTGGTATTGCTGCGATGCTGAATTCATTAGTGTCGTATTCGCTGTCCAAGGCTGATTCTTGGGATCTGCCGACCGC
GACGCGCTGGCTTACCGGCTCGCTCAATGGTGCGACGTGGGATCGTGCGATGCCGCTGATTGTCACCACTGTGGTACTCA
TTCCGCTGCTGGTGGCTAATGCGCGCAATGTGGATCTTATGCGTTTGGGCAATGATTCCGCGGTGGGTTTGGGCGTTGCT
ACTAATCGCACGCGCGTCATTGCGATTATTGCCGCTGTTGCGCTCATCGCCGTTGCTACCGCTGCATGCGGCCCGATCGC
ATTCGTGGCGTTTGTGTCTGGCCCCATTGCCGCGCGCATTTTAGGCTCCGGCGGATCGCTCATCATCCCCTCCGCACTCA
TCGGCGGGTTGATCGTGCTCATCGCCGACCTAATTGGCCAATACTTCCTCGGCACCCGCTACCCCGTCGGAGTTGTCACC
GGCGCATTCGGCGCCCCATTCCTTATCTATTTACTCATTCGTTCCAACCGCGCGGGAGTAACCCTGTGA

Upstream 100 bases:

>100_bases
TGGTGACTCGTCCGAGTGAAATTGCCGTGGGCATCATCATGCCGATCATTGGTGCGCCACTGTTTATTTGGATTATTCGT
CGTCAGAAAGTCAAAGAGCT

Downstream 100 bases:

>100_bases
CCACCAACCATCAACTATCCGCCGAAGAAATTTCCCTGGCGTACGGCGAGCGCACCATCATCGATTCGCTCAGCGTCGAC
ATCGTCCCCGGCAAAATCAC

Product: ABC-type cobalamin/Fe3+-siderophores transport system, permease component

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MSLSHQLKRQRASRNSRRWLIVAALGVVTLGIFAFSLMWGEVFYGPAQVLKVLSGQQVPGASYSVGVLRLPRAVMGLTAG
LAFGAAGVIFQTVLRNQLASPDIIGISSGASAAGVICIVFFGMSQSAVSAISLCASLAVALLIYLVAYRGGFSATRLILT
GIGIAAMLNSLVSYSLSKADSWDLPTATRWLTGSLNGATWDRAMPLIVTTVVLIPLLVANARNVDLMRLGNDSAVGLGVA
TNRTRVIAIIAAVALIAVATAACGPIAFVAFVSGPIAARILGSGGSLIIPSALIGGLIVLIADLIGQYFLGTRYPVGVVT
GAFGAPFLIYLLIRSNRAGVTL

Sequences:

>Translated_342_residues
MSLSHQLKRQRASRNSRRWLIVAALGVVTLGIFAFSLMWGEVFYGPAQVLKVLSGQQVPGASYSVGVLRLPRAVMGLTAG
LAFGAAGVIFQTVLRNQLASPDIIGISSGASAAGVICIVFFGMSQSAVSAISLCASLAVALLIYLVAYRGGFSATRLILT
GIGIAAMLNSLVSYSLSKADSWDLPTATRWLTGSLNGATWDRAMPLIVTTVVLIPLLVANARNVDLMRLGNDSAVGLGVA
TNRTRVIAIIAAVALIAVATAACGPIAFVAFVSGPIAARILGSGGSLIIPSALIGGLIVLIADLIGQYFLGTRYPVGVVT
GAFGAPFLIYLLIRSNRAGVTL
>Mature_341_residues
SLSHQLKRQRASRNSRRWLIVAALGVVTLGIFAFSLMWGEVFYGPAQVLKVLSGQQVPGASYSVGVLRLPRAVMGLTAGL
AFGAAGVIFQTVLRNQLASPDIIGISSGASAAGVICIVFFGMSQSAVSAISLCASLAVALLIYLVAYRGGFSATRLILTG
IGIAAMLNSLVSYSLSKADSWDLPTATRWLTGSLNGATWDRAMPLIVTTVVLIPLLVANARNVDLMRLGNDSAVGLGVAT
NRTRVIAIIAAVALIAVATAACGPIAFVAFVSGPIAARILGSGGSLIIPSALIGGLIVLIADLIGQYFLGTRYPVGVVTG
AFGAPFLIYLLIRSNRAGVTL

Specific function: Part of the ABC transporter complex yfiYZ/yfhA/yusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786804, Length=329, Percent_Identity=36.7781155015198, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1790740, Length=276, Percent_Identity=36.5942028985507, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1786347, Length=319, Percent_Identity=32.6018808777429, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1786805, Length=315, Percent_Identity=34.2857142857143, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788004, Length=285, Percent_Identity=29.8245614035088, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790741, Length=275, Percent_Identity=27.6363636363636, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35316; Mature: 35185

Theoretical pI: Translated: 11.30; Mature: 11.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSHQLKRQRASRNSRRWLIVAALGVVTLGIFAFSLMWGEVFYGPAQVLKVLSGQQVPG
CCCHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCC
ASYSVGVLRLPRAVMGLTAGLAFGAAGVIFQTVLRNQLASPDIIGISSGASAAGVICIVF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHEE
FGMSQSAVSAISLCASLAVALLIYLVAYRGGFSATRLILTGIGIAAMLNSLVSYSLSKAD
ECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SWDLPTATRWLTGSLNGATWDRAMPLIVTTVVLIPLLVANARNVDLMRLGNDSAVGLGVA
CCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEE
TNRTRVIAIIAAVALIAVATAACGPIAFVAFVSGPIAARILGSGGSLIIPSALIGGLIVL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCEEHHHHHHHHHHHH
IADLIGQYFLGTRYPVGVVTGAFGAPFLIYLLIRSNRAGVTL
HHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SLSHQLKRQRASRNSRRWLIVAALGVVTLGIFAFSLMWGEVFYGPAQVLKVLSGQQVPG
CCHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCC
ASYSVGVLRLPRAVMGLTAGLAFGAAGVIFQTVLRNQLASPDIIGISSGASAAGVICIVF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHEE
FGMSQSAVSAISLCASLAVALLIYLVAYRGGFSATRLILTGIGIAAMLNSLVSYSLSKAD
ECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SWDLPTATRWLTGSLNGATWDRAMPLIVTTVVLIPLLVANARNVDLMRLGNDSAVGLGVA
CCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEE
TNRTRVIAIIAAVALIAVATAACGPIAFVAFVSGPIAARILGSGGSLIIPSALIGGLIVL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCEEHHHHHHHHHHHH
IADLIGQYFLGTRYPVGVVTGAFGAPFLIYLLIRSNRAGVTL
HHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]