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The map label for this gene is 62389516

Identifier: 62389516

GI number: 62389516

Start: 637547

End: 639739

Strand: Reverse

Name: 62389516

Synonym: cg0722

Alternate gene names: NA

Gene position: 639739-637547 (Counterclockwise)

Preceding gene: 62389517

Following gene: 62389515

Centisome position: 19.49

GC content: 50.34

Gene sequence:

>2193_bases
ATGTCTACTAGCATCACAACAGAGAACAAGAAGAAATCTGGTCCTCCTCGCTTGATGAGAATCTTTCTGCCCGCCTTGCT
AATTTTAGTTTGGCTTGTAGGAGCTGGAGTCGGCGGTCCTTATTTTGGCAAGGTTAGTGAGGTCTCCTCCAACAGCCAGA
CCACATATCTGCCAGAATCTGCCGATGCCACTCAAGTACAGGAACAGTTGGGAGATTTTACTGATTCTGAATCCATCCCA
GCCATTGTCGTAATGGTCAGCGATGAACCCTTAACACAGCAAGACATCACACAACTCAATGAAGTTGTTGCTGGGCTTTC
AGAATTAGACATAGTTTCCGATGAAGTCTCCCCTGCTATTCCATCCGAGGACGGCAGAGCTGTCCAAGTGTTTGTCCCCC
TCAATCCATCAGCGGAGCTGACGGAAAGCGTCGAGAAGCTCTCTGAGACCTTGACCCAGCAAACGCCGGACTATGTGAGC
ACCTATGTGACCGGACCGGCTGGGTTTACCGCTGATCTCAGCGCAGCTTTCGCGGGTATTGATGGGCTACTCCTAGCAGT
CGCCTTGGCTGCCGTCCTTGTCATTCTTGTCATCGTCTATCGCTCCTTCATTCTGCCCATCGCCGTGCTTGCCACCAGTT
TGTTTGCGCTGACTGTAGCTCTATTGGTGGTGTGGTGGCTAGCTAAGTGGGACATCCTGCTGCTTTCGGGTCAGACTCAA
GGCATCCTCTTCATTCTGGTCATTGGCGCCGCCACCGACTACTCATTGCTATACGTTGCTCGTTTCCGTGAAGAGTTACG
CGTTCAACAAGATAAAGGGATAGCCACAGGGAAAGCCATCCGGGCATCGGTGGAACCCATTCTTGCCTCGGGCAGCACTG
TTATTGCGGGCCTCCTTTGTTTGCTATTTAGTGATTTGAAATCTAACTCCACGCTAGGTCCAGTAGCTTCGGTGGGCATT
ATTTTTGCAATGCTTTCTGCTCTTACTCTGCTACCAGCCCTGCTGTTTGTATTCGGTCGGGTGGCCTTTTGGCCCAAGCG
ACCAAAATACGAACCTGAAAAAGCCCGTGCGAAAAACGACATCCCCGCCAGCGGGATCTGGTCAAAAGTGGCTGATTTAG
TGGAGCAGCATCCTCGTGCAATCTGGGTATCTACACTTATTGTGCTTCTCTTGGGTGCGGCTTTCGTTCCCACACTAAAA
GCGGACGGTGTGTCCCAATCCGACCTAGTTCTGGGTTCCTCTGAAGCACGTGATGGCCAGCAGGCTTTAGGCGAACACTT
CCCCGGTGGATCCGGCAGTCCTGCTTATATTATCGTTGATGAAACACAGGCAGCACAGGCTGCTGACGTAGTCCTTAACA
ACGACAATTTCGAGACTGTAACTGTAACTAGTGCTGACTCCCCCTCTGGCTCAGCCCCAATCACCGCTGACGGTATTGTG
CCGTTAGGTTCTGGTACAGCTCCAGGCCCGGTAGTTGTAGAAGGGCAAGTCCTTTTACAAGCAACACTTGTCGAAGCACC
AGATTCCGAAGAAGCTCAAAAAGCTATTCGCAGTATCCGCCAAACTTTTGCAGATGAAAATATATCAGCGGTAGTAGGCG
GTGTCACTGCAACTTCCGTAGACACTAACGATGCCTCCATCCATGACCGCAACCTGATCATCCCAATTGTATTGCTGGTC
ATTTTGGTTATTCTCATGCTGTTGCTGCGGTCTATTGTCGCACCACTCCTGCTAGTAGTCACCACCGTGGTGTCTTTTGC
TACTGCTTTAGGCGTGGCTGCTTTACTTTTCAATCACGTTTTCAGTTTCCCAGGAGCAGACCCCGCAGTACCTCTCTACG
GATTTGTATTTTTAGTAGCCTTGGGCATCGACTACAACATTTTCTTAGTCACCCGAATCCGTGAAGAAACCAAAACCCAC
GGCACAAGACTTGGAATTCTTCGAGGCCTGACAGTAACCGGCGGAGTAATTACCTCAGCTGGAGTAGTTCTCGCCGCAAC
GTTCGCAGCACTCTATGTCATCCCAATTCTATTCCTGGCACAAATTGCCTTCATTGTCGCTTTTGGAGTTCTTATTGATA
CCCTGCTCGTTCGCGCCTTCTTGGTGCCTGCTTTGTTCTACGACATCGGACCGAAAATCTGGTGGCCGTCAAAATTGTCC
AATCAGAAATACCAGAAGCAGCCTCAGCTATGA

Upstream 100 bases:

>100_bases
TAGATCCCAAGGCTCAAAATTTATTACTTAAACAAGTTGAGCAACTAGCCAGCCGCAAATCTTAGAACTAACCTTTACGC
CTTTAACGGAAGTGAATTTG

Downstream 100 bases:

>100_bases
CACACCAAAATTCGCCTCTCTTCCTTAAAAGTGCACTGAGACTTTACAATCGGGCCTCATTCAAGGCTTCACATAAAGTG
ATCGAAGAATATTCGACGAG

Product: RND superfamily drug efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 730; Mature: 729

Protein sequence:

>730_residues
MSTSITTENKKKSGPPRLMRIFLPALLILVWLVGAGVGGPYFGKVSEVSSNSQTTYLPESADATQVQEQLGDFTDSESIP
AIVVMVSDEPLTQQDITQLNEVVAGLSELDIVSDEVSPAIPSEDGRAVQVFVPLNPSAELTESVEKLSETLTQQTPDYVS
TYVTGPAGFTADLSAAFAGIDGLLLAVALAAVLVILVIVYRSFILPIAVLATSLFALTVALLVVWWLAKWDILLLSGQTQ
GILFILVIGAATDYSLLYVARFREELRVQQDKGIATGKAIRASVEPILASGSTVIAGLLCLLFSDLKSNSTLGPVASVGI
IFAMLSALTLLPALLFVFGRVAFWPKRPKYEPEKARAKNDIPASGIWSKVADLVEQHPRAIWVSTLIVLLLGAAFVPTLK
ADGVSQSDLVLGSSEARDGQQALGEHFPGGSGSPAYIIVDETQAAQAADVVLNNDNFETVTVTSADSPSGSAPITADGIV
PLGSGTAPGPVVVEGQVLLQATLVEAPDSEEAQKAIRSIRQTFADENISAVVGGVTATSVDTNDASIHDRNLIIPIVLLV
ILVILMLLLRSIVAPLLLVVTTVVSFATALGVAALLFNHVFSFPGADPAVPLYGFVFLVALGIDYNIFLVTRIREETKTH
GTRLGILRGLTVTGGVITSAGVVLAATFAALYVIPILFLAQIAFIVAFGVLIDTLLVRAFLVPALFYDIGPKIWWPSKLS
NQKYQKQPQL

Sequences:

>Translated_730_residues
MSTSITTENKKKSGPPRLMRIFLPALLILVWLVGAGVGGPYFGKVSEVSSNSQTTYLPESADATQVQEQLGDFTDSESIP
AIVVMVSDEPLTQQDITQLNEVVAGLSELDIVSDEVSPAIPSEDGRAVQVFVPLNPSAELTESVEKLSETLTQQTPDYVS
TYVTGPAGFTADLSAAFAGIDGLLLAVALAAVLVILVIVYRSFILPIAVLATSLFALTVALLVVWWLAKWDILLLSGQTQ
GILFILVIGAATDYSLLYVARFREELRVQQDKGIATGKAIRASVEPILASGSTVIAGLLCLLFSDLKSNSTLGPVASVGI
IFAMLSALTLLPALLFVFGRVAFWPKRPKYEPEKARAKNDIPASGIWSKVADLVEQHPRAIWVSTLIVLLLGAAFVPTLK
ADGVSQSDLVLGSSEARDGQQALGEHFPGGSGSPAYIIVDETQAAQAADVVLNNDNFETVTVTSADSPSGSAPITADGIV
PLGSGTAPGPVVVEGQVLLQATLVEAPDSEEAQKAIRSIRQTFADENISAVVGGVTATSVDTNDASIHDRNLIIPIVLLV
ILVILMLLLRSIVAPLLLVVTTVVSFATALGVAALLFNHVFSFPGADPAVPLYGFVFLVALGIDYNIFLVTRIREETKTH
GTRLGILRGLTVTGGVITSAGVVLAATFAALYVIPILFLAQIAFIVAFGVLIDTLLVRAFLVPALFYDIGPKIWWPSKLS
NQKYQKQPQL
>Mature_729_residues
STSITTENKKKSGPPRLMRIFLPALLILVWLVGAGVGGPYFGKVSEVSSNSQTTYLPESADATQVQEQLGDFTDSESIPA
IVVMVSDEPLTQQDITQLNEVVAGLSELDIVSDEVSPAIPSEDGRAVQVFVPLNPSAELTESVEKLSETLTQQTPDYVST
YVTGPAGFTADLSAAFAGIDGLLLAVALAAVLVILVIVYRSFILPIAVLATSLFALTVALLVVWWLAKWDILLLSGQTQG
ILFILVIGAATDYSLLYVARFREELRVQQDKGIATGKAIRASVEPILASGSTVIAGLLCLLFSDLKSNSTLGPVASVGII
FAMLSALTLLPALLFVFGRVAFWPKRPKYEPEKARAKNDIPASGIWSKVADLVEQHPRAIWVSTLIVLLLGAAFVPTLKA
DGVSQSDLVLGSSEARDGQQALGEHFPGGSGSPAYIIVDETQAAQAADVVLNNDNFETVTVTSADSPSGSAPITADGIVP
LGSGTAPGPVVVEGQVLLQATLVEAPDSEEAQKAIRSIRQTFADENISAVVGGVTATSVDTNDASIHDRNLIIPIVLLVI
LVILMLLLRSIVAPLLLVVTTVVSFATALGVAALLFNHVFSFPGADPAVPLYGFVFLVALGIDYNIFLVTRIREETKTHG
TRLGILRGLTVTGGVITSAGVVLAATFAALYVIPILFLAQIAFIVAFGVLIDTLLVRAFLVPALFYDIGPKIWWPSKLSN
QKYQKQPQL

Specific function: Unknown

COG id: COG2409

COG function: function code R; Predicted drug exporters of the RND superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004869
- InterPro:   IPR000731 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 77331; Mature: 77199

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS50156 SSD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSITTENKKKSGPPRLMRIFLPALLILVWLVGAGVGGPYFGKVSEVSSNSQTTYLPES
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCEEECCCC
ADATQVQEQLGDFTDSESIPAIVVMVSDEPLTQQDITQLNEVVAGLSELDIVSDEVSPAI
CCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCCC
PSEDGRAVQVFVPLNPSAELTESVEKLSETLTQQTPDYVSTYVTGPAGFTADLSAAFAGI
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHH
DGLLLAVALAAVLVILVIVYRSFILPIAVLATSLFALTVALLVVWWLAKWDILLLSGQTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCC
GILFILVIGAATDYSLLYVARFREELRVQQDKGIATGKAIRASVEPILASGSTVIAGLLC
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
LLFSDLKSNSTLGPVASVGIIFAMLSALTLLPALLFVFGRVAFWPKRPKYEPEKARAKND
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCC
IPASGIWSKVADLVEQHPRAIWVSTLIVLLLGAAFVPTLKADGVSQSDLVLGSSEARDGQ
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCHH
QALGEHFPGGSGSPAYIIVDETQAAQAADVVLNNDNFETVTVTSADSPSGSAPITADGIV
HHHHHCCCCCCCCCEEEEEECCCCHHHHHEEECCCCCEEEEEECCCCCCCCCCCCCCCCE
PLGSGTAPGPVVVEGQVLLQATLVEAPDSEEAQKAIRSIRQTFADENISAVVGGVTATSV
ECCCCCCCCCEEEECHHEEHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEC
DTNDASIHDRNLIIPIVLLVILVILMLLLRSIVAPLLLVVTTVVSFATALGVAALLFNHV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSFPGADPAVPLYGFVFLVALGIDYNIFLVTRIREETKTHGTRLGILRGLTVTGGVITSA
HCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHCCCHHHHHHCCHHCCCHHHHH
GVVLAATFAALYVIPILFLAQIAFIVAFGVLIDTLLVRAFLVPALFYDIGPKIWWPSKLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHC
NQKYQKQPQL
CCHHHCCCCC
>Mature Secondary Structure 
STSITTENKKKSGPPRLMRIFLPALLILVWLVGAGVGGPYFGKVSEVSSNSQTTYLPES
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCEEECCCC
ADATQVQEQLGDFTDSESIPAIVVMVSDEPLTQQDITQLNEVVAGLSELDIVSDEVSPAI
CCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHCCCCCC
PSEDGRAVQVFVPLNPSAELTESVEKLSETLTQQTPDYVSTYVTGPAGFTADLSAAFAGI
CCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHH
DGLLLAVALAAVLVILVIVYRSFILPIAVLATSLFALTVALLVVWWLAKWDILLLSGQTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCC
GILFILVIGAATDYSLLYVARFREELRVQQDKGIATGKAIRASVEPILASGSTVIAGLLC
CEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
LLFSDLKSNSTLGPVASVGIIFAMLSALTLLPALLFVFGRVAFWPKRPKYEPEKARAKND
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCC
IPASGIWSKVADLVEQHPRAIWVSTLIVLLLGAAFVPTLKADGVSQSDLVLGSSEARDGQ
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCHH
QALGEHFPGGSGSPAYIIVDETQAAQAADVVLNNDNFETVTVTSADSPSGSAPITADGIV
HHHHHCCCCCCCCCEEEEEECCCCHHHHHEEECCCCCEEEEEECCCCCCCCCCCCCCCCE
PLGSGTAPGPVVVEGQVLLQATLVEAPDSEEAQKAIRSIRQTFADENISAVVGGVTATSV
ECCCCCCCCCEEEECHHEEHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEC
DTNDASIHDRNLIIPIVLLVILVILMLLLRSIVAPLLLVVTTVVSFATALGVAALLFNHV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSFPGADPAVPLYGFVFLVALGIDYNIFLVTRIREETKTHGTRLGILRGLTVTGGVITSA
HCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHCCCHHHHHHCCHHCCCHHHHH
GVVLAATFAALYVIPILFLAQIAFIVAFGVLIDTLLVRAFLVPALFYDIGPKIWWPSKLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHC
NQKYQKQPQL
CCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]