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The map label for this gene is 62389464

Identifier: 62389464

GI number: 62389464

Start: 586397

End: 587641

Strand: Reverse

Name: 62389464

Synonym: cg0665

Alternate gene names: NA

Gene position: 587641-586397 (Counterclockwise)

Preceding gene: 62389465

Following gene: 62389459

Centisome position: 17.9

GC content: 55.34

Gene sequence:

>1245_bases
ATGCGCAGACTCATCGCGGTTAGCTTGGCCGCTCTGTTTATGTTGGCTTCCACTCCAGCGACGAGGGCACAGGAAGTAGA
AGCTCTCGCTTGCCCCGAGGTAGCGATCGCCGATCCTTCCTCCGCAGTTTTAGATGAACACCTTTCGCAGTCATTATCCC
AAGCTCACCAACTAGCAACTGGCGCCGGTGTGATGGTGGCAGTCATCGACACCGGAGTATCCCTGCATCCACGTCTGCCC
CACTTAATTCCCGGCGGTGATTTCGTGGGCGCCCACCAAAGCCCCGATGTGCCAGGTGAACTTATCGATTGCGACGGCCA
CGGCACCATCGTCGCCGGAATCATCGCCTCCCAAGGAAACCCCGGCACCGGCTGGCCATATGACGGCAGCTCCGATCCTT
ATATCGGTGTCGCCCCAGATTCCGGAATCATCTCCATTAAACAAACCAGCTCATATGTGCGTACTCGTGAAGATTCCAAC
GTCGGAACGCTGAGCACCCTGGCGGAATCCATCCACCGAGCTCTCGATTCCGGTGCCCACGTGATCAATATTTCCGTGGT
GTCCTGTTTGCCCCAATCACCCGACGAGGCCGCATCGTTCCAGCCTCTGACGGATGCTCTTAACAGAGCAGAACTTCAAG
GGGTGATAGTGGTGGCAGCAGCAGGAAACCTCGGGCAGGATTGTCCAGTTGGATCTACCGTTTATCCTGCACATTCAGAC
ACTGTGCTCTCTGTGTCGGCACGTTTTGATTCTCACACGCTTGCAGAATATTCCATGCCTGGCAACCAACAAATCCTCTC
TGCACCAAGCCACATTCAGGCTGGTCTATCACCGCGTGGCGACGGCTTCGCCAGCCACATGATCACCACCGCTGGCGAAA
GCCCCTTCGAGGGCACCAGTTTTGCCGCTCCAGTTGTCAGCGCCACAGCTGCACTGCTTCGCCAGCATTTTCCCTTTGCC
ACACCCTATGAAATTCGTGCACGAATCTTCAACAGCATCGACCCTGCAAGAGGCGCTATTGATCCCTACCTGGCACTTAC
TCAAGAAATCTATCCCACCACTCCCCTGGTTCATGAGATCGCACTAAGTGTTCCCACGCCGCCGGATGATTCTCCACGGG
AGCGGGGCATCCTAGTTACCGCAATCATTGTTGGGTTGCTCGCAGTGTTAGCTGTGCTGATGGGACTACGCCGAATTCAT
CATCACTCGGCCTTTCAAAAAGCTAGCTCAAGTGTTATCACTTAA

Upstream 100 bases:

>100_bases
TTGGAATCACTGTGTCTTGCAGCTAGTCTGCCACTCGCACTGCATTTGCTGGATGTATTTGGAATGCTGCGCGGTCTTGA
TATTGGATTCGGTGGATAAG

Downstream 100 bases:

>100_bases
TCTATGAGGCACCGTTCAGAATCCCATCAACCGCAAGAGCCCAAACCAACTACACAAACGACTCAGGAATCTGTATCGCA
TGCCTTGGATGAGATCTTTT

Product: serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MRRLIAVSLAALFMLASTPATRAQEVEALACPEVAIADPSSAVLDEHLSQSLSQAHQLATGAGVMVAVIDTGVSLHPRLP
HLIPGGDFVGAHQSPDVPGELIDCDGHGTIVAGIIASQGNPGTGWPYDGSSDPYIGVAPDSGIISIKQTSSYVRTREDSN
VGTLSTLAESIHRALDSGAHVINISVVSCLPQSPDEAASFQPLTDALNRAELQGVIVVAAAGNLGQDCPVGSTVYPAHSD
TVLSVSARFDSHTLAEYSMPGNQQILSAPSHIQAGLSPRGDGFASHMITTAGESPFEGTSFAAPVVSATAALLRQHFPFA
TPYEIRARIFNSIDPARGAIDPYLALTQEIYPTTPLVHEIALSVPTPPDDSPRERGILVTAIIVGLLAVLAVLMGLRRIH
HHSAFQKASSSVIT

Sequences:

>Translated_414_residues
MRRLIAVSLAALFMLASTPATRAQEVEALACPEVAIADPSSAVLDEHLSQSLSQAHQLATGAGVMVAVIDTGVSLHPRLP
HLIPGGDFVGAHQSPDVPGELIDCDGHGTIVAGIIASQGNPGTGWPYDGSSDPYIGVAPDSGIISIKQTSSYVRTREDSN
VGTLSTLAESIHRALDSGAHVINISVVSCLPQSPDEAASFQPLTDALNRAELQGVIVVAAAGNLGQDCPVGSTVYPAHSD
TVLSVSARFDSHTLAEYSMPGNQQILSAPSHIQAGLSPRGDGFASHMITTAGESPFEGTSFAAPVVSATAALLRQHFPFA
TPYEIRARIFNSIDPARGAIDPYLALTQEIYPTTPLVHEIALSVPTPPDDSPRERGILVTAIIVGLLAVLAVLMGLRRIH
HHSAFQKASSSVIT
>Mature_414_residues
MRRLIAVSLAALFMLASTPATRAQEVEALACPEVAIADPSSAVLDEHLSQSLSQAHQLATGAGVMVAVIDTGVSLHPRLP
HLIPGGDFVGAHQSPDVPGELIDCDGHGTIVAGIIASQGNPGTGWPYDGSSDPYIGVAPDSGIISIKQTSSYVRTREDSN
VGTLSTLAESIHRALDSGAHVINISVVSCLPQSPDEAASFQPLTDALNRAELQGVIVVAAAGNLGQDCPVGSTVYPAHSD
TVLSVSARFDSHTLAEYSMPGNQQILSAPSHIQAGLSPRGDGFASHMITTAGESPFEGTSFAAPVVSATAALLRQHFPFA
TPYEIRARIFNSIDPARGAIDPYLALTQEIYPTTPLVHEIALSVPTPPDDSPRERGILVTAIIVGLLAVLAVLMGLRRIH
HHSAFQKASSSVIT

Specific function: Shows keratinolytic activity [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020
- InterPro:   IPR010259 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 43144; Mature: 43144

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLIAVSLAALFMLASTPATRAQEVEALACPEVAIADPSSAVLDEHLSQSLSQAHQLAT
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHC
GAGVMVAVIDTGVSLHPRLPHLIPGGDFVGAHQSPDVPGELIDCDGHGTIVAGIIASQGN
CCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEECCCC
PGTGWPYDGSSDPYIGVAPDSGIISIKQTSSYVRTREDSNVGTLSTLAESIHRALDSGAH
CCCCCCCCCCCCCEEEECCCCCEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCE
VINISVVSCLPQSPDEAASFQPLTDALNRAELQGVIVVAAAGNLGQDCPVGSTVYPAHSD
EEEEEEEECCCCCCCHHCCCCHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCEECCCCCC
TVLSVSARFDSHTLAEYSMPGNQQILSAPSHIQAGLSPRGDGFASHMITTAGESPFEGTS
EEEEEEECCCCCCHHHCCCCCCHHHHCCCHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCC
FAAPVVSATAALLRQHFPFATPYEIRARIFNSIDPARGAIDPYLALTQEIYPTTPLVHEI
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHH
ALSVPTPPDDSPRERGILVTAIIVGLLAVLAVLMGLRRIHHHSAFQKASSSVIT
HCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRRLIAVSLAALFMLASTPATRAQEVEALACPEVAIADPSSAVLDEHLSQSLSQAHQLAT
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHC
GAGVMVAVIDTGVSLHPRLPHLIPGGDFVGAHQSPDVPGELIDCDGHGTIVAGIIASQGN
CCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEECCCC
PGTGWPYDGSSDPYIGVAPDSGIISIKQTSSYVRTREDSNVGTLSTLAESIHRALDSGAH
CCCCCCCCCCCCCEEEECCCCCEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCE
VINISVVSCLPQSPDEAASFQPLTDALNRAELQGVIVVAAAGNLGQDCPVGSTVYPAHSD
EEEEEEEECCCCCCCHHCCCCHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCEECCCCCC
TVLSVSARFDSHTLAEYSMPGNQQILSAPSHIQAGLSPRGDGFASHMITTAGESPFEGTS
EEEEEEECCCCCCHHHCCCCCCHHHHCCCHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCC
FAAPVVSATAALLRQHFPFATPYEIRARIFNSIDPARGAIDPYLALTQEIYPTTPLVHEI
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHH
ALSVPTPPDDSPRERGILVTAIIVGLLAVLAVLMGLRRIHHHSAFQKASSSVIT
HCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1369007; 11058132; 1370008 [H]