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The map label for this gene is kipR [H]

Identifier: 62389445

GI number: 62389445

Start: 568271

End: 569077

Strand: Reverse

Name: kipR [H]

Synonym: cg0646

Alternate gene names: 62389445

Gene position: 569077-568271 (Counterclockwise)

Preceding gene: 62389458

Following gene: 62389444

Centisome position: 17.34

GC content: 53.16

Gene sequence:

>807_bases
ATGGCGGGAGGAAATCGCGAACCTGGACGTACAGTCACCTCCAAGGTGATCGCCGTACTGGGAGCTTTTGAACACACCAT
GCGTCCACTTGGTGTCACTGAAATCGCTGAGCTGGCAGACCTCCCACCAAGTACCACCCACCGTCTCGTTTCTGAATTAA
CCGAAGGCGGACTACTCAGCAAGAAATCTGATGGGCGCTACCAATTGGGCTTACGTATCTGGGAACTCGCCCAAAATACA
GGACGGCAGTTACGCGACACTGCACGCCCGTTCATCCAAGAGCTCTACTCACTTACTTCCGAGACTGCGCAGCTAGTGGT
CCGCGATAAAGATGAAGCACTTTTGATTGACCGAGCCTACGGCACGAAGAAAATTCCACGCTCGGCTCGAGTCGGTGGTC
GACTACCTCTGAACTCCACTGCGGTTGGCAAGATTCTCCTTGCGTTTGATGAGCCATGGGTAAAACAGTCCTATCTCAAG
CTGCCACTCAACGCCTCCACCCCAAAGACAATTGTGAATCCCGACGTCTTGGCTGCGCAGCTGAAACAAATTCACTCGCA
AGGCTTTGCCATCACACATGACGAGCAACGAATCGGCGGCGCATCGATCGCCGTACCGGTCTGGCATACAGGAAAACTGG
GAGCAGCACTGGGGTTGGTGGTTCCCACCGCACAGGCTGCAAATCTTGAGCGCTATCTCCCGATCCTTCAGGCGACAAGT
CAGAGAATTACAAAAGCAACCGCGCTCATTCCTTTGGACACACTTTTGGCTTCACACAAAAATGCAGAACGAAAAGGCGA
TACCTAA

Upstream 100 bases:

>100_bases
ATAGGCTTGAACAATACGTCGTTACACTGGCCGATTTGATACCTTTCAAAACTTTTACCCTTCATCGGAGTGCCAGGGGA
ACTTAGAGGAGCATTAAATA

Downstream 100 bases:

>100_bases
ACCCGCCCTCCATCTGCATAAACTAAAACTGATTCCACTGAGTGGAATCTGAATTCGTATCTTCATCTCTTCTTGACGAC
ACTTTGAGTCACACCTAAAA

Product: IclR family regulatory protein

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MAGGNREPGRTVTSKVIAVLGAFEHTMRPLGVTEIAELADLPPSTTHRLVSELTEGGLLSKKSDGRYQLGLRIWELAQNT
GRQLRDTARPFIQELYSLTSETAQLVVRDKDEALLIDRAYGTKKIPRSARVGGRLPLNSTAVGKILLAFDEPWVKQSYLK
LPLNASTPKTIVNPDVLAAQLKQIHSQGFAITHDEQRIGGASIAVPVWHTGKLGAALGLVVPTAQAANLERYLPILQATS
QRITKATALIPLDTLLASHKNAERKGDT

Sequences:

>Translated_268_residues
MAGGNREPGRTVTSKVIAVLGAFEHTMRPLGVTEIAELADLPPSTTHRLVSELTEGGLLSKKSDGRYQLGLRIWELAQNT
GRQLRDTARPFIQELYSLTSETAQLVVRDKDEALLIDRAYGTKKIPRSARVGGRLPLNSTAVGKILLAFDEPWVKQSYLK
LPLNASTPKTIVNPDVLAAQLKQIHSQGFAITHDEQRIGGASIAVPVWHTGKLGAALGLVVPTAQAANLERYLPILQATS
QRITKATALIPLDTLLASHKNAERKGDT
>Mature_267_residues
AGGNREPGRTVTSKVIAVLGAFEHTMRPLGVTEIAELADLPPSTTHRLVSELTEGGLLSKKSDGRYQLGLRIWELAQNTG
RQLRDTARPFIQELYSLTSETAQLVVRDKDEALLIDRAYGTKKIPRSARVGGRLPLNSTAVGKILLAFDEPWVKQSYLKL
PLNASTPKTIVNPDVLAAQLKQIHSQGFAITHDEQRIGGASIAVPVWHTGKLGAALGLVVPTAQAANLERYLPILQATSQ
RITKATALIPLDTLLASHKNAERKGDT

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=255, Percent_Identity=29.8039215686275, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786468, Length=225, Percent_Identity=29.3333333333333, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786715, Length=258, Percent_Identity=27.5193798449612, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082359, Length=185, Percent_Identity=28.6486486486486, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789999, Length=234, Percent_Identity=28.2051282051282, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788581, Length=196, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790752, Length=226, Percent_Identity=26.5486725663717, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29044; Mature: 28913

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGGNREPGRTVTSKVIAVLGAFEHTMRPLGVTEIAELADLPPSTTHRLVSELTEGGLLS
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCC
KKSDGRYQLGLRIWELAQNTGRQLRDTARPFIQELYSLTSETAQLVVRDKDEALLIDRAY
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCC
GTKKIPRSARVGGRLPLNSTAVGKILLAFDEPWVKQSYLKLPLNASTPKTIVNPDVLAAQ
CCCCCCCHHCCCCCCCCCCHHHHEEEEEECCCHHHHHHEECCCCCCCCCCCCCHHHHHHH
LKQIHSQGFAITHDEQRIGGASIAVPVWHTGKLGAALGLVVPTAQAANLERYLPILQATS
HHHHHHCCCEEECCHHHCCCCEEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
QRITKATALIPLDTLLASHKNAERKGDT
HHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AGGNREPGRTVTSKVIAVLGAFEHTMRPLGVTEIAELADLPPSTTHRLVSELTEGGLLS
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCC
KKSDGRYQLGLRIWELAQNTGRQLRDTARPFIQELYSLTSETAQLVVRDKDEALLIDRAY
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCC
GTKKIPRSARVGGRLPLNSTAVGKILLAFDEPWVKQSYLKLPLNASTPKTIVNPDVLAAQ
CCCCCCCHHCCCCCCCCCCHHHHEEEEEECCCHHHHHHEECCCCCCCCCCCCCHHHHHHH
LKQIHSQGFAITHDEQRIGGASIAVPVWHTGKLGAALGLVVPTAQAANLERYLPILQATS
HHHHHHCCCEEECCHHHCCCCEEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
QRITKATALIPLDTLLASHKNAERKGDT
HHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]