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The map label for this gene is fdhF [C]

Identifier: 62389421

GI number: 62389421

Start: 544753

End: 547041

Strand: Reverse

Name: fdhF [C]

Synonym: cg0618

Alternate gene names: 62389421

Gene position: 547041-544753 (Counterclockwise)

Preceding gene: 62389423

Following gene: 62389420

Centisome position: 16.66

GC content: 52.6

Gene sequence:

>2289_bases
ATGACAACCCCTCCAACTGAGATTTCGAACGTGAATCCCACCGCGAATGAATTTGATGATCCGGATGTGGGACGGCGCAT
TACTTCTGCTGCTGGTGTGCCAGGCGTTTTGCATGCGCTCCAGCATGCTGTTCCGAATCGTGCCCTGCTGCCGTTGCTCA
CCATGAATAAACCAGGCGGCATCGACTGTCCTGGTTGTGCTTGGCCTGAGCCTTCCACTGCCAACCTTGGTGTGGTTGAG
TTCTGCGAGAACGGTGCCAAGGCGGTCGCCGAGGAAACAACACCTGATCGTGCCGGCAAAGAGTTCTGGGCAGAGCATTC
TATTTATGATCTGCGGGAAAAGACCGATCACTGGCTGGGAAAGCGTGGCCGAATCACCGAGCCCATGTTTTATGATCGTT
CTTCTGGCGATGATCACTACCGCCCTATTTCTTGGGATCGTGCATTTGCGATCATTGCGTCGAAGCTCCGCGAGATCGAG
CCAGATGAAGCGGTGTTTTACACCTCTGGTCGAGCACCCAATGAGCCGGCTTATATGCTGCAGCTTCTAGCCCGCCGACT
TGGCACAAATAATCTTCCAGACTGTGGAAACATGTGCCACGAGTCCACCGGTACTGCCTTGGGTGAGACCTTGGGTTTGG
GCAAGGGATCCGTGGTGATGGAGGATTTCTACAACACTGATTTGTTGATTTCCGTGGGACAAAACCCGGGCACCAACCAC
CCACGTGCGTTGACGGCTTTCAAAGAATTGAAGGAAAACGGTGGCAAGATTCTGGCGCTGAACCCCATGCCAGAGACCGG
TCTGATGAAATTCCGTGAGCCCCAATCAGTCAAGGGCGCGTTGAGCATTTCAGACAAACTTGCTGATGAATACTTGCAGA
TCCGTCTTGATGGAGACCGCGCATTCTTCCAGGCGCTCAACAAGGAACTCATCCGTAGAGATGCCCTAGATCATGCATTC
TTGGATAAATTCTGTTCAGGTGTGGATGAAACCATCGAGCACCTCAAATCACTCGATGATGAGGTTCTGCTCAAGGGATG
CGGTCTGACGGCAGCGGAGATCAACAAGGCCGCTGACATGGTGGAAAAGTCTGACACCGTGGTGGTGTCATGGACTCTCG
GGGTCACCCAGCATAAGAACGCTGTGTACACCATCCGTGAAATGGTGAACTTCCTGCTGCTTACTGGAAATATTGGTAAG
CCTGGCGCAGGCACTGCCCCGCTTCGTGGGCACTCAAACGTCCAGGGTGATCGAACCATGGGTATTTGGGAGAAAATGCC
GGAGGCATTCCTTGCTGCTCTTGAAAACGAGTTTGGTTTCGATGTGCCCCGCAAGCACGGCTTCGACACGGTAAATTCCC
TGCGAGCCATGCGCGAAGGCAAGACCAAGTTCTTTCTCTCCCTCGGTGGCAACCTTGTTCGAGTGTCCTCAGATACGTCT
GTTGTCGAAAAGGGCATGGAATCCAATGAGCTGACGGTGCATCTGTCGACCAAGCCCAATGGTTCACAAGCATGGCCTGG
TGAGCAGTCACTTATCCTTCCGGTGATTGCTCGAACAGATAAGGATGTCCAAAAGTCAGGCGTCCAGCGTGTGACAGTTG
AGGATTCTGCCGGCGCTGTTCACGCATCCACTGGTAAACGAACCGCCAACAAGGATCTGAATTTGAAGTCCGAATGCGAC
ATCATTGGAACCATCGGTAAGCAGACCTTCGGTGATGCCTTCTGGCAGCCGATGATTGATAACTACGATGTGGTCCGCGA
TCACATCGAGGCCACCATTCCTGGGTTCCACGATTTCAACCGTCGCATCGACAACCCCGGTGGATTCCTCCTCCCCAACG
GACCTCGTGAGCGCATCTTCAACACATCCAATGGCAAGGCCCAATTGACGGTTAATGAAACCAATGTGATTGAGCTACCC
AAGGACTATTTGCTTATGAACACGGTACGTTCACATGATCAATACAACTCCACGATTTACGGTCTGGATGACCGCTACCG
CGGTGTTCGCAATGGTCGCCGCGTAGTGTTCGTCAATCCTCAAGATTGTAAGCAACGTGGTCTCAAGGATGGAGACATCG
TCGATATCGTCTCTGTCTTTGATGATGGCGAACGCCGAGCACCGAATTTCCGAGTGGTGGAATATGACACCGCGAGGGAC
TGCGTCACCACGTATTTCCCTGAGGCCAACGTATTGGTTCCATTGGATTCAGTAGCTGAAAAATCCAACACTCCAGTGTC
CAAGTCAGTTGTGGTTCGCCTTGAAGCAACAGGACGTACTGCTTCTTAG

Upstream 100 bases:

>100_bases
CTGGGAGTCCTCTTGATTTTAGGTTTTCCACATACCCCCATATAGATTGAAGAATTCATTTTTCGGCATGGGTTCAATTG
CCGGGTCTAGACTGTGACCT

Downstream 100 bases:

>100_bases
AAAAACACCAGGGAATTTTCCGCGCCCGCTTCCTTGTTTAAATAAACGAGGATGCGGGCTTATTTATAATTGCAGTTTTA
CAATTGCAGCCATCATCAGA

Product: formate dehydrogenase oxidoreductase protein

Products: CO2; NADH

Alternate protein names: NA

Number of amino acids: Translated: 762; Mature: 761

Protein sequence:

>762_residues
MTTPPTEISNVNPTANEFDDPDVGRRITSAAGVPGVLHALQHAVPNRALLPLLTMNKPGGIDCPGCAWPEPSTANLGVVE
FCENGAKAVAEETTPDRAGKEFWAEHSIYDLREKTDHWLGKRGRITEPMFYDRSSGDDHYRPISWDRAFAIIASKLREIE
PDEAVFYTSGRAPNEPAYMLQLLARRLGTNNLPDCGNMCHESTGTALGETLGLGKGSVVMEDFYNTDLLISVGQNPGTNH
PRALTAFKELKENGGKILALNPMPETGLMKFREPQSVKGALSISDKLADEYLQIRLDGDRAFFQALNKELIRRDALDHAF
LDKFCSGVDETIEHLKSLDDEVLLKGCGLTAAEINKAADMVEKSDTVVVSWTLGVTQHKNAVYTIREMVNFLLLTGNIGK
PGAGTAPLRGHSNVQGDRTMGIWEKMPEAFLAALENEFGFDVPRKHGFDTVNSLRAMREGKTKFFLSLGGNLVRVSSDTS
VVEKGMESNELTVHLSTKPNGSQAWPGEQSLILPVIARTDKDVQKSGVQRVTVEDSAGAVHASTGKRTANKDLNLKSECD
IIGTIGKQTFGDAFWQPMIDNYDVVRDHIEATIPGFHDFNRRIDNPGGFLLPNGPRERIFNTSNGKAQLTVNETNVIELP
KDYLLMNTVRSHDQYNSTIYGLDDRYRGVRNGRRVVFVNPQDCKQRGLKDGDIVDIVSVFDDGERRAPNFRVVEYDTARD
CVTTYFPEANVLVPLDSVAEKSNTPVSKSVVVRLEATGRTAS

Sequences:

>Translated_762_residues
MTTPPTEISNVNPTANEFDDPDVGRRITSAAGVPGVLHALQHAVPNRALLPLLTMNKPGGIDCPGCAWPEPSTANLGVVE
FCENGAKAVAEETTPDRAGKEFWAEHSIYDLREKTDHWLGKRGRITEPMFYDRSSGDDHYRPISWDRAFAIIASKLREIE
PDEAVFYTSGRAPNEPAYMLQLLARRLGTNNLPDCGNMCHESTGTALGETLGLGKGSVVMEDFYNTDLLISVGQNPGTNH
PRALTAFKELKENGGKILALNPMPETGLMKFREPQSVKGALSISDKLADEYLQIRLDGDRAFFQALNKELIRRDALDHAF
LDKFCSGVDETIEHLKSLDDEVLLKGCGLTAAEINKAADMVEKSDTVVVSWTLGVTQHKNAVYTIREMVNFLLLTGNIGK
PGAGTAPLRGHSNVQGDRTMGIWEKMPEAFLAALENEFGFDVPRKHGFDTVNSLRAMREGKTKFFLSLGGNLVRVSSDTS
VVEKGMESNELTVHLSTKPNGSQAWPGEQSLILPVIARTDKDVQKSGVQRVTVEDSAGAVHASTGKRTANKDLNLKSECD
IIGTIGKQTFGDAFWQPMIDNYDVVRDHIEATIPGFHDFNRRIDNPGGFLLPNGPRERIFNTSNGKAQLTVNETNVIELP
KDYLLMNTVRSHDQYNSTIYGLDDRYRGVRNGRRVVFVNPQDCKQRGLKDGDIVDIVSVFDDGERRAPNFRVVEYDTARD
CVTTYFPEANVLVPLDSVAEKSNTPVSKSVVVRLEATGRTAS
>Mature_761_residues
TTPPTEISNVNPTANEFDDPDVGRRITSAAGVPGVLHALQHAVPNRALLPLLTMNKPGGIDCPGCAWPEPSTANLGVVEF
CENGAKAVAEETTPDRAGKEFWAEHSIYDLREKTDHWLGKRGRITEPMFYDRSSGDDHYRPISWDRAFAIIASKLREIEP
DEAVFYTSGRAPNEPAYMLQLLARRLGTNNLPDCGNMCHESTGTALGETLGLGKGSVVMEDFYNTDLLISVGQNPGTNHP
RALTAFKELKENGGKILALNPMPETGLMKFREPQSVKGALSISDKLADEYLQIRLDGDRAFFQALNKELIRRDALDHAFL
DKFCSGVDETIEHLKSLDDEVLLKGCGLTAAEINKAADMVEKSDTVVVSWTLGVTQHKNAVYTIREMVNFLLLTGNIGKP
GAGTAPLRGHSNVQGDRTMGIWEKMPEAFLAALENEFGFDVPRKHGFDTVNSLRAMREGKTKFFLSLGGNLVRVSSDTSV
VEKGMESNELTVHLSTKPNGSQAWPGEQSLILPVIARTDKDVQKSGVQRVTVEDSAGAVHASTGKRTANKDLNLKSECDI
IGTIGKQTFGDAFWQPMIDNYDVVRDHIEATIPGFHDFNRRIDNPGGFLLPNGPRERIFNTSNGKAQLTVNETNVIELPK
DYLLMNTVRSHDQYNSTIYGLDDRYRGVRNGRRVVFVNPQDCKQRGLKDGDIVDIVSVFDDGERRAPNFRVVEYDTARDC
VTTYFPEANVLVPLDSVAEKSNTPVSKSVVVRLEATGRTAS

Specific function: Unknown

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787778, Length=752, Percent_Identity=40.0265957446808, Blast_Score=556, Evalue=1e-159,
Organism=Escherichia coli, GI3868721, Length=388, Percent_Identity=27.8350515463918, Blast_Score=145, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR010046 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.2.1.2

Molecular weight: Translated: 83922; Mature: 83791

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPPTEISNVNPTANEFDDPDVGRRITSAAGVPGVLHALQHAVPNRALLPLLTMNKPGG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCCCC
IDCPGCAWPEPSTANLGVVEFCENGAKAVAEETTPDRAGKEFWAEHSIYDLREKTDHWLG
CCCCCCCCCCCCCCCCHHHHHHHCCHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHC
KRGRITEPMFYDRSSGDDHYRPISWDRAFAIIASKLREIEPDEAVFYTSGRAPNEPAYML
CCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHH
QLLARRLGTNNLPDCGNMCHESTGTALGETLGLGKGSVVMEDFYNTDLLISVGQNPGTNH
HHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHCCCCCCEEEHHHCCCEEEEEECCCCCCCC
PRALTAFKELKENGGKILALNPMPETGLMKFREPQSVKGALSISDKLADEYLQIRLDGDR
CHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCH
AFFQALNKELIRRDALDHAFLDKFCSGVDETIEHLKSLDDEVLLKGCGLTAAEINKAADM
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHH
VEKSDTVVVSWTLGVTQHKNAVYTIREMVNFLLLTGNIGKPGAGTAPLRGHSNVQGDRTM
HHCCCCEEEEEEECCEECCCHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCH
GIWEKMPEAFLAALENEFGFDVPRKHGFDTVNSLRAMREGKTKFFLSLGGNLVRVSSDTS
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCEEEECCCHH
VVEKGMESNELTVHLSTKPNGSQAWPGEQSLILPVIARTDKDVQKSGVQRVTVEDSAGAV
HHHCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHCCCEEEEEECCCCEE
HASTGKRTANKDLNLKSECDIIGTIGKQTFGDAFWQPMIDNYDVVRDHIEATIPGFHDFN
ECCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHH
RRIDNPGGFLLPNGPRERIFNTSNGKAQLTVNETNVIELPKDYLLMNTVRSHDQYNSTIY
HHCCCCCCEECCCCCHHHCEECCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHCCEEE
GLDDRYRGVRNGRRVVFVNPQDCKQRGLKDGDIVDIVSVFDDGERRAPNFRVVEYDTARD
ECCHHHHHHCCCCEEEEECCHHHHHCCCCCCCCEEHHHHHCCCCCCCCCEEEEEECCHHH
CVTTYFPEANVLVPLDSVAEKSNTPVSKSVVVRLEATGRTAS
HHHHHCCCCCEEEECHHHHHCCCCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure 
TTPPTEISNVNPTANEFDDPDVGRRITSAAGVPGVLHALQHAVPNRALLPLLTMNKPGG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEEECCCCC
IDCPGCAWPEPSTANLGVVEFCENGAKAVAEETTPDRAGKEFWAEHSIYDLREKTDHWLG
CCCCCCCCCCCCCCCCHHHHHHHCCHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHC
KRGRITEPMFYDRSSGDDHYRPISWDRAFAIIASKLREIEPDEAVFYTSGRAPNEPAYML
CCCCCCCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHH
QLLARRLGTNNLPDCGNMCHESTGTALGETLGLGKGSVVMEDFYNTDLLISVGQNPGTNH
HHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHCCCCCCEEEHHHCCCEEEEEECCCCCCCC
PRALTAFKELKENGGKILALNPMPETGLMKFREPQSVKGALSISDKLADEYLQIRLDGDR
CHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCH
AFFQALNKELIRRDALDHAFLDKFCSGVDETIEHLKSLDDEVLLKGCGLTAAEINKAADM
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHH
VEKSDTVVVSWTLGVTQHKNAVYTIREMVNFLLLTGNIGKPGAGTAPLRGHSNVQGDRTM
HHCCCCEEEEEEECCEECCCHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCH
GIWEKMPEAFLAALENEFGFDVPRKHGFDTVNSLRAMREGKTKFFLSLGGNLVRVSSDTS
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCEEEECCCHH
VVEKGMESNELTVHLSTKPNGSQAWPGEQSLILPVIARTDKDVQKSGVQRVTVEDSAGAV
HHHCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHCCCEEEEEECCCCEE
HASTGKRTANKDLNLKSECDIIGTIGKQTFGDAFWQPMIDNYDVVRDHIEATIPGFHDFN
ECCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHH
RRIDNPGGFLLPNGPRERIFNTSNGKAQLTVNETNVIELPKDYLLMNTVRSHDQYNSTIY
HHCCCCCCEECCCCCHHHCEECCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHCCEEE
GLDDRYRGVRNGRRVVFVNPQDCKQRGLKDGDIVDIVSVFDDGERRAPNFRVVEYDTARD
ECCHHHHHHCCCCEEEEECCHHHHHCCCCCCCCEEHHHHHCCCCCCCCCEEEEEECCHHH
CVTTYFPEANVLVPLDSVAEKSNTPVSKSVVVRLEATGRTAS
HHHHHCCCCCEEEECHHHHHCCCCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate; NAD+

Specific reaction: formate + NAD+ = CO2 + NADH

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]