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The map label for this gene is deoC

Identifier: 62389282

GI number: 62389282

Start: 405479

End: 406147

Strand: Direct

Name: deoC

Synonym: cg0458

Alternate gene names: 62389282

Gene position: 405479-406147 (Clockwise)

Preceding gene: 62389280

Following gene: 62389283

Centisome position: 12.35

GC content: 54.41

Gene sequence:

>669_bases
ATGACGATTTCCCGCTCCACCATGGCCCAAATCCTTGACTACACCCTCCTCGGACCAGAAGTAACCAACTCCGAACTGGC
CGCATTTATAGATTCCGCAATTGAGCTGGGAGTCGGCACGATCTGTGTCCCCAACAGCATGGTCAACCTAACTGCAAAAG
CCCAAGAAGCTGGAATTCGAGTGGCCACCGTCGCAGGATTCCCGCACGGCAAAACCCCCGCGTTGGTGAAAGCCGCCGAA
GCGCGCCTTGCCGTACAGTCCGGAGCTTCCGAAGTAGATGTTGTTTTGGATATTGCGGTAGTGAAAGAGGGAGATGCCAA
TAGGTTGCTGCAGGAAATTGTGGCAATCAGGGAGGCTGTTCCATCTCCTGTGGTGCTGAAATTCATCCTCGAAACAGCTG
TTGTGAGTGATGAAGCAATTGTGACTGCAGTGAATGCGTTGATTGCTGCTGGTGCTGACTTCGCTAAAACTTCCACGGGA
TTCCACCCAGCGGGAGGGGCAACTGTTGAGGCTGTTCGGGTGATGGCTTCGGCTTCTCGGGGAAGGGTTGGAATTAAGGC
TGCCGGTGGGGTGAAAACTTGGGAAGATGCGGTGGCGTTTGTTGAAGCAGGGGCTACTCGCATTGGAACTTCTAATGCGG
GAGCCATTTTGGAGGGTGCGCCGGAGTAG

Upstream 100 bases:

>100_bases
CGCTCGGACGATTACGAACTTCAGGAGAACTCGGGGTCATTCGTTGCATTCTACCCTGGAAATTTTCCCACACTAAGTCA
GGTCTAAGTAGGGTATGGAT

Downstream 100 bases:

>100_bases
TTTGGCGTTCTAATCGGGACTGATGGGTAATTGAGGGCGGTTAAGAGGGTTCGAAGTTCGATTCGGGGGTCGGGCTTCGG
GGCAATGCAAAAATCCACCA

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MTISRSTMAQILDYTLLGPEVTNSELAAFIDSAIELGVGTICVPNSMVNLTAKAQEAGIRVATVAGFPHGKTPALVKAAE
ARLAVQSGASEVDVVLDIAVVKEGDANRLLQEIVAIREAVPSPVVLKFILETAVVSDEAIVTAVNALIAAGADFAKTSTG
FHPAGGATVEAVRVMASASRGRVGIKAAGGVKTWEDAVAFVEAGATRIGTSNAGAILEGAPE

Sequences:

>Translated_222_residues
MTISRSTMAQILDYTLLGPEVTNSELAAFIDSAIELGVGTICVPNSMVNLTAKAQEAGIRVATVAGFPHGKTPALVKAAE
ARLAVQSGASEVDVVLDIAVVKEGDANRLLQEIVAIREAVPSPVVLKFILETAVVSDEAIVTAVNALIAAGADFAKTSTG
FHPAGGATVEAVRVMASASRGRVGIKAAGGVKTWEDAVAFVEAGATRIGTSNAGAILEGAPE
>Mature_221_residues
TISRSTMAQILDYTLLGPEVTNSELAAFIDSAIELGVGTICVPNSMVNLTAKAQEAGIRVATVAGFPHGKTPALVKAAEA
RLAVQSGASEVDVVLDIAVVKEGDANRLLQEIVAIREAVPSPVVLKFILETAVVSDEAIVTAVNALIAAGADFAKTSTGF
HPAGGATVEAVRVMASASRGRVGIKAAGGVKTWEDAVAFVEAGATRIGTSNAGAILEGAPE

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=172, Percent_Identity=34.3023255813954, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1790841, Length=206, Percent_Identity=36.4077669902913, Blast_Score=86, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17533015, Length=211, Percent_Identity=31.7535545023697, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19922098, Length=188, Percent_Identity=30.3191489361702, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_CORGL (Q8NTC4)

Other databases:

- EMBL:   BA000036
- EMBL:   BX927149
- RefSeq:   NP_599631.1
- RefSeq:   YP_224684.1
- ProteinModelPortal:   Q8NTC4
- SMR:   Q8NTC4
- GeneID:   1021418
- GeneID:   3344707
- GenomeReviews:   BA000036_GR
- GenomeReviews:   BX927147_GR
- KEGG:   cgb:cg0458
- KEGG:   cgl:NCgl0372
- HOGENOM:   HBG636421
- OMA:   EEKIAMC
- PhylomeDB:   Q8NTC4
- ProtClustDB:   PRK00507
- BioCyc:   CGLU196627:CG0458-MONOMER
- BRENDA:   4.1.2.4
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 22520; Mature: 22389

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: ACT_SITE 156-156 ACT_SITE 186-186

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISRSTMAQILDYTLLGPEVTNSELAAFIDSAIELGVGTICVPNSMVNLTAKAQEAGIR
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCEEEEEHHHHCCEE
VATVAGFPHGKTPALVKAAEARLAVQSGASEVDVVLDIAVVKEGDANRLLQEIVAIREAV
EEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHC
PSPVVLKFILETAVVSDEAIVTAVNALIAAGADFAKTSTGFHPAGGATVEAVRVMASASR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHHCC
GRVGIKAAGGVKTWEDAVAFVEAGATRIGTSNAGAILEGAPE
CCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCCC
>Mature Secondary Structure 
TISRSTMAQILDYTLLGPEVTNSELAAFIDSAIELGVGTICVPNSMVNLTAKAQEAGIR
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCEEEEEHHHHCCEE
VATVAGFPHGKTPALVKAAEARLAVQSGASEVDVVLDIAVVKEGDANRLLQEIVAIREAV
EEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHC
PSPVVLKFILETAVVSDEAIVTAVNALIAAGADFAKTSTGFHPAGGATVEAVRVMASASR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHHCC
GRVGIKAAGGVKTWEDAVAFVEAGATRIGTSNAGAILEGAPE
CCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626