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The map label for this gene is wzx [H]

Identifier: 62389249

GI number: 62389249

Start: 371930

End: 373423

Strand: Direct

Name: wzx [H]

Synonym: cg0421

Alternate gene names: 62389249

Gene position: 371930-373423 (Clockwise)

Preceding gene: 62389248

Following gene: 62389250

Centisome position: 11.33

GC content: 42.1

Gene sequence:

>1494_bases
ATGGCAAATACTAGAGATGAAGCTACTGAAGTACCTGAAGATGGCTCTTTGAGGAAGGGCGCAGCTCGGGGATCCGCTAT
CACTTTAGTAGGGCAGATTACGAGAATTTTGATTCAGTTACTCAGCGTAATCTTACTAGCTAGATTAATTCCTCCTGCAG
ATTTTGGTTTATACGCTATGGTCCTTGCAGTTTCAGGCGTGGCTCAGATCTTTCTCGATCTAGGGTTTTCTATGGCGGCC
CTGAGATCACGTGATCTAACTAAGCAACAACATTCAAATCTATTTTGGATTAATACTTCCGCTGGTTTTCTTCTATTTAT
TATTATTTTTTCACTTGCGATTCCTTTAGCAACTTTCTATGGAGATGATCGATTAATAAGGGTTACACAGTGGATATCTA
TTGTGTACCTGTTGGGGGGAATCACTGCTCAGTTTAGGGTCCATTTAAATCGTCACCTGCGATTTGGAGCTTTATCTCTT
GCAGATGTTTTAGCACCGTTGGTAGCTCTCGTAGTGGCCGTAATTATGGCAATGAAGGGTTATGGAGTTCAAGCTCTTGT
GGTTCAAACAATATTGAACTACTTAGTTATGCTGGTTTTGGTTGTCGTGATGGCCCGGTGGGTTCCGAGTTTTCCTCGTA
AGACTCCCGGTATGAAGCCATTGCTTACTTTTGGTATGGGACTTGGCGCGACTAGATTCTTATCTTATTTAACTCAAAAT
ATTGATAGTATTATTATTGGCCGGGTGATGGGGCCAGTTCAGCTCGGGTTTTATGATCGTGCATTTAGGCTGGCAGTCGC
ACCTGTTGTGCAAATTAGTTTCCCATTCACACGTGTAGCAATACCATTTTTAGTTCGTGTAATGGATGATGGAAAAAAGT
ATGTTGCCGCACTACGTGAAGCTCAAATGGTCGGCATCTATGGAACTGCTAGTTTTCTTTTGGTTTTTGGCGGTATGGCT
ACACCAATTGTGACCTTAATTTTTGGTCCTGATTGGGTAGAAGCGGGACTTCTGATGACAATTCTATGCATAGGTGCAAT
ATTCCGTACATTGCAACAGGTTGCTACTTGGGTATTTATGTCAAAAGGACTGTCCGGGGCATTGCTGAAGCTAAATCTTG
TCATGCAACCGGTGATCGTATTGTTAATCATCGGTGGTGCTCGATGGGGCACGGTTGGTGTTGCATGGGCAGGGACTCTG
GGATACTTTCTGTTTTGGTTGGTCTCAATAGCTTGGGCAAGTTATGCCACTAATTTAAATTTGTGGAGTTTAGTCACAAA
TCCTCTAGAGATTATCGGTAAATTTAGCCTTCCTGCGGGGCTTATTACTTTTGCGATTTCGTCAAATTCATCCCTTTCGC
TATTAACACAGTTCTTGGCATCTATTGGTGGTGCATTGATTTGGTTTGTATTCATTTATTGCATCTCAAAGAAGATTAAA
AAAGATATTCGCCGACTAGTTGGAATCGGAATGCTAGTTTTAAAGAGGCGTTGA

Upstream 100 bases:

>100_bases
TTTTACCTATTGGTGCGAAGAATCAGATCCACCCTATTGATCTGAACATTAAAACGAAATGTAGCTAATTTAGATCGCGA
ATTTATATGGAAGAAGACCG

Downstream 100 bases:

>100_bases
GGGGTAGTATCGCGTAAGTTTATTAGTGGTTAGCGTAGATTTTTCGAATTGAAGATGTTTCTGAAAGGTATTTAGATATG
TATGCAGAAATTAATGGCGG

Product: translocase involved in export of a cell surface polysaccaride

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 496

Protein sequence:

>497_residues
MANTRDEATEVPEDGSLRKGAARGSAITLVGQITRILIQLLSVILLARLIPPADFGLYAMVLAVSGVAQIFLDLGFSMAA
LRSRDLTKQQHSNLFWINTSAGFLLFIIIFSLAIPLATFYGDDRLIRVTQWISIVYLLGGITAQFRVHLNRHLRFGALSL
ADVLAPLVALVVAVIMAMKGYGVQALVVQTILNYLVMLVLVVVMARWVPSFPRKTPGMKPLLTFGMGLGATRFLSYLTQN
IDSIIIGRVMGPVQLGFYDRAFRLAVAPVVQISFPFTRVAIPFLVRVMDDGKKYVAALREAQMVGIYGTASFLLVFGGMA
TPIVTLIFGPDWVEAGLLMTILCIGAIFRTLQQVATWVFMSKGLSGALLKLNLVMQPVIVLLIIGGARWGTVGVAWAGTL
GYFLFWLVSIAWASYATNLNLWSLVTNPLEIIGKFSLPAGLITFAISSNSSLSLLTQFLASIGGALIWFVFIYCISKKIK
KDIRRLVGIGMLVLKRR

Sequences:

>Translated_497_residues
MANTRDEATEVPEDGSLRKGAARGSAITLVGQITRILIQLLSVILLARLIPPADFGLYAMVLAVSGVAQIFLDLGFSMAA
LRSRDLTKQQHSNLFWINTSAGFLLFIIIFSLAIPLATFYGDDRLIRVTQWISIVYLLGGITAQFRVHLNRHLRFGALSL
ADVLAPLVALVVAVIMAMKGYGVQALVVQTILNYLVMLVLVVVMARWVPSFPRKTPGMKPLLTFGMGLGATRFLSYLTQN
IDSIIIGRVMGPVQLGFYDRAFRLAVAPVVQISFPFTRVAIPFLVRVMDDGKKYVAALREAQMVGIYGTASFLLVFGGMA
TPIVTLIFGPDWVEAGLLMTILCIGAIFRTLQQVATWVFMSKGLSGALLKLNLVMQPVIVLLIIGGARWGTVGVAWAGTL
GYFLFWLVSIAWASYATNLNLWSLVTNPLEIIGKFSLPAGLITFAISSNSSLSLLTQFLASIGGALIWFVFIYCISKKIK
KDIRRLVGIGMLVLKRR
>Mature_496_residues
ANTRDEATEVPEDGSLRKGAARGSAITLVGQITRILIQLLSVILLARLIPPADFGLYAMVLAVSGVAQIFLDLGFSMAAL
RSRDLTKQQHSNLFWINTSAGFLLFIIIFSLAIPLATFYGDDRLIRVTQWISIVYLLGGITAQFRVHLNRHLRFGALSLA
DVLAPLVALVVAVIMAMKGYGVQALVVQTILNYLVMLVLVVVMARWVPSFPRKTPGMKPLLTFGMGLGATRFLSYLTQNI
DSIIIGRVMGPVQLGFYDRAFRLAVAPVVQISFPFTRVAIPFLVRVMDDGKKYVAALREAQMVGIYGTASFLLVFGGMAT
PIVTLIFGPDWVEAGLLMTILCIGAIFRTLQQVATWVFMSKGLSGALLKLNLVMQPVIVLLIIGGARWGTVGVAWAGTLG
YFLFWLVSIAWASYATNLNLWSLVTNPLEIIGKFSLPAGLITFAISSNSSLSLLTQFLASIGGALIWFVFIYCISKKIKK
DIRRLVGIGMLVLKRR

Specific function: Might be involved in the translocation of teichuronic acid repeating units from the inner to the outer surface of the membrane [H]

COG id: COG2244

COG function: function code R; Membrane protein involved in the export of O-antigen and teichoic acid

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788359, Length=406, Percent_Identity=23.3990147783251, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002797 [H]

Pfam domain/function: PF01943 Polysacc_synt [H]

EC number: NA

Molecular weight: Translated: 54340; Mature: 54209

Theoretical pI: Translated: 10.87; Mature: 10.87

Prosite motif: PS00041 HTH_ARAC_FAMILY_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTRDEATEVPEDGSLRKGAARGSAITLVGQITRILIQLLSVILLARLIPPADFGLYAM
CCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
VLAVSGVAQIFLDLGFSMAALRSRDLTKQQHSNLFWINTSAGFLLFIIIFSLAIPLATFY
HHHHHHHHHHHHHHCHHHHHHHHHHCCHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHC
GDDRLIRVTQWISIVYLLGGITAQFRVHLNRHLRFGALSLADVLAPLVALVVAVIMAMKG
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YGVQALVVQTILNYLVMLVLVVVMARWVPSFPRKTPGMKPLLTFGMGLGATRFLSYLTQN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHH
IDSIIIGRVMGPVQLGFYDRAFRLAVAPVVQISFPFTRVAIPFLVRVMDDGKKYVAALRE
HHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHH
AQMVGIYGTASFLLVFGGMATPIVTLIFGPDWVEAGLLMTILCIGAIFRTLQQVATWVFM
HHHEEEEHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKGLSGALLKLNLVMQPVIVLLIIGGARWGTVGVAWAGTLGYFLFWLVSIAWASYATNLN
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
LWSLVTNPLEIIGKFSLPAGLITFAISSNSSLSLLTQFLASIGGALIWFVFIYCISKKIK
HHHHHHHHHHHHHCCCCCHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDIRRLVGIGMLVLKRR
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANTRDEATEVPEDGSLRKGAARGSAITLVGQITRILIQLLSVILLARLIPPADFGLYAM
CCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH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HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10048024; 9384377 [H]