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The map label for this gene is asd [H]

Identifier: 62389150

GI number: 62389150

Start: 270660

End: 271694

Strand: Direct

Name: asd [H]

Synonym: cg0307

Alternate gene names: 62389150

Gene position: 270660-271694 (Clockwise)

Preceding gene: 62389149

Following gene: 62389151

Centisome position: 8.25

GC content: 56.43

Gene sequence:

>1035_bases
ATGACCACCATCGCAGTTGTTGGTGCAACCGGCCAGGTCGGCCAGGTTATGCGCACCCTTTTGGAAGAGCGCAATTTCCC
AGCTGACACTGTTCGTTTCTTTGCTTCCCCACGTTCCGCAGGCCGTAAGATTGAATTCCGTGGCACGGAAATCGAGGTAG
AAGACATTACTCAGGCAACCGAGGAGTCCCTCAAGGACATCGACGTTGCGTTGTTCTCCGCTGGAGGCACCGCTTCCAAG
CAGTACGCTCCACTGTTCGCTGCTGCAGGCGCGACTGTTGTGGATAACTCTTCTGCTTGGCGCAAGGACGACGAGGTTCC
ACTAATCGTCTCTGAGGTGAACCCTTCCGACAAGGATTCCCTGGTCAAGGGCATTATTGCGAACCCTAACTGCACCACCA
TGGCTGCGATGCCAGTGCTGAAGCCACTTCACGATGCCGCTGGTCTTGTAAAGCTTCACGTTTCCTCTTACCAGGCTGTT
TCCGGTTCTGGTCTTGCAGGTGTGGAAACCTTGGCAAAGCAGGTTGCTGCAGTTGGAGACCACAACGTTGAGTTCGTCCA
TGATGGACAGGCTGCTGACGCAGGCGATGTCGGACCTTATGTTTCACCAATCGCTTACAACGTGCTGCCATTCGCCGGAA
ACCTCGTCGATGACGGCACCTTCGAAACCGATGAAGAGCAGAAGCTGCGCAACGAATCCCGCAAGATTCTCGGTCTCCCA
GACCTCAAGGTCTCAGGCACCTGCGTCCGCGTGCCGGTTTTCACCGGCCACACGCTGACCATTCACGCCGAATTCGACAA
GGCAATCACCGTGGACCAGGCGCAGGAGATCTTGGGTGCCGCTTCAGGCGTCAAGCTTGTCGACGTCCCAACCCCACTTG
CAGCTGCCGGCATTGACGAATCCCTCGTTGGACGCATCCGTCAGGACTCCACTGTCGACGATAACCGCGGTCTGGTTCTC
GTCGTATCTGGCGACAACCTCCGCAAGGGTGCTGCGCTAAACACCATCCAGATCGCTGAGCTGCTGGTTAAGTAA

Upstream 100 bases:

>100_bases
CTGCACGTGCATTGCATGAGCAGTTCCAGCTGGGCGGCGAAGACGAAGCCGTCGTTTATGCAGGCACCGGACGCTAAAGT
TTTAAAGGAGTAGTTTTACA

Downstream 100 bases:

>100_bases
AAACCCGCCATTAAAAACTCCGCTTGAGTGCTACACTTTAAGCGGGGTTTTAATGTTTGAGGGGCGATGGGGGTCGAGCT
TGTGAAGTGGAATTTTCCAC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTTIAVVGATGQVGQVMRTLLEERNFPADTVRFFASPRSAGRKIEFRGTEIEVEDITQATEESLKDIDVALFSAGGTASK
QYAPLFAAAGATVVDNSSAWRKDDEVPLIVSEVNPSDKDSLVKGIIANPNCTTMAAMPVLKPLHDAAGLVKLHVSSYQAV
SGSGLAGVETLAKQVAAVGDHNVEFVHDGQAADAGDVGPYVSPIAYNVLPFAGNLVDDGTFETDEEQKLRNESRKILGLP
DLKVSGTCVRVPVFTGHTLTIHAEFDKAITVDQAQEILGAASGVKLVDVPTPLAAAGIDESLVGRIRQDSTVDDNRGLVL
VVSGDNLRKGAALNTIQIAELLVK

Sequences:

>Translated_344_residues
MTTIAVVGATGQVGQVMRTLLEERNFPADTVRFFASPRSAGRKIEFRGTEIEVEDITQATEESLKDIDVALFSAGGTASK
QYAPLFAAAGATVVDNSSAWRKDDEVPLIVSEVNPSDKDSLVKGIIANPNCTTMAAMPVLKPLHDAAGLVKLHVSSYQAV
SGSGLAGVETLAKQVAAVGDHNVEFVHDGQAADAGDVGPYVSPIAYNVLPFAGNLVDDGTFETDEEQKLRNESRKILGLP
DLKVSGTCVRVPVFTGHTLTIHAEFDKAITVDQAQEILGAASGVKLVDVPTPLAAAGIDESLVGRIRQDSTVDDNRGLVL
VVSGDNLRKGAALNTIQIAELLVK
>Mature_343_residues
TTIAVVGATGQVGQVMRTLLEERNFPADTVRFFASPRSAGRKIEFRGTEIEVEDITQATEESLKDIDVALFSAGGTASKQ
YAPLFAAAGATVVDNSSAWRKDDEVPLIVSEVNPSDKDSLVKGIIANPNCTTMAAMPVLKPLHDAAGLVKLHVSSYQAVS
GSGLAGVETLAKQVAAVGDHNVEFVHDGQAADAGDVGPYVSPIAYNVLPFAGNLVDDGTFETDEEQKLRNESRKILGLPD
LKVSGTCVRVPVFTGHTLTIHAEFDKAITVDQAQEILGAASGVKLVDVPTPLAAAGIDESLVGRIRQDSTVDDNRGLVLV
VSGDNLRKGAALNTIQIAELLVK

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=347, Percent_Identity=31.700288184438, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789841, Length=366, Percent_Identity=26.775956284153, Blast_Score=82, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320362, Length=389, Percent_Identity=27.5064267352185, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36212; Mature: 36081

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIAVVGATGQVGQVMRTLLEERNFPADTVRFFASPRSAGRKIEFRGTEIEVEDITQAT
CCEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCEEEEECCEEEHHHHHHHH
EESLKDIDVALFSAGGTASKQYAPLFAAAGATVVDNSSAWRKDDEVPLIVSEVNPSDKDS
HHHHHHHEEEEEECCCCCCCCCCCCHHHCCCEEEECCCCCCCCCCCCEEEECCCCCCHHH
LVKGIIANPNCTTMAAMPVLKPLHDAAGLVKLHVSSYQAVSGSGLAGVETLAKQVAAVGD
HHHHEECCCCCCHHHHHHHHHHHHHHCCEEEEEECCEEEECCCCCHHHHHHHHHHHHCCC
HNVEFVHDGQAADAGDVGPYVSPIAYNVLPFAGNLVDDGTFETDEEQKLRNESRKILGLP
CCEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCEEECCC
DLKVSGTCVRVPVFTGHTLTIHAEFDKAITVDQAQEILGAASGVKLVDVPTPLAAAGIDE
CCEECCEEEEEEEEECCEEEEEECCCCEEEHHHHHHHHHHCCCCEEEECCCCHHHHCCCH
SLVGRIRQDSTVDDNRGLVLVVSGDNLRKGAALNTIQIAELLVK
HHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
TTIAVVGATGQVGQVMRTLLEERNFPADTVRFFASPRSAGRKIEFRGTEIEVEDITQAT
CEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCEEEEECCEEEHHHHHHHH
EESLKDIDVALFSAGGTASKQYAPLFAAAGATVVDNSSAWRKDDEVPLIVSEVNPSDKDS
HHHHHHHEEEEEECCCCCCCCCCCCHHHCCCEEEECCCCCCCCCCCCEEEECCCCCCHHH
LVKGIIANPNCTTMAAMPVLKPLHDAAGLVKLHVSSYQAVSGSGLAGVETLAKQVAAVGD
HHHHEECCCCCCHHHHHHHHHHHHHHCCEEEEEECCEEEECCCCCHHHHHHHHHHHHCCC
HNVEFVHDGQAADAGDVGPYVSPIAYNVLPFAGNLVDDGTFETDEEQKLRNESRKILGLP
CCEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCEEECCC
DLKVSGTCVRVPVFTGHTLTIHAEFDKAITVDQAQEILGAASGVKLVDVPTPLAAAGIDE
CCEECCEEEEEEEEECCEEEEEECCCCEEEHHHHHHHHHHCCCCEEEECCCCHHHHCCCH
SLVGRIRQDSTVDDNRGLVLVVSGDNLRKGAALNTIQIAELLVK
HHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8100567 [H]