Click here to switch to the map view.

The map label for this gene is blaI [H]

Identifier: 62388912

GI number: 62388912

Start: 19705

End: 20076

Strand: Direct

Name: blaI [H]

Synonym: cg0027

Alternate gene names: 62388912

Gene position: 19705-20076 (Clockwise)

Preceding gene: 62388909

Following gene: 62388913

Centisome position: 0.6

GC content: 54.3

Gene sequence:

>372_bases
ATGAGCATCGAGCCAGGAATCCCCACGCTTGGACCGCTTGAAGAACAAGTCATGCACATTCTGTGGGATCACGGAAAATT
GACAGTCCGTGAAGTCATCGAATTCCTTCCAGGTGATCCTGCGTACACAACGATCGCAACCGTCCTGCGTCACTTGGGCA
GAAAAGGCATGGTCACCACCGTCAAAGATGGTCGGACTGCCCGGCACAGCGCGTTGATGAACAGGGAGCAATACACCGCC
GGCATCATGGACCAGGTGCTGTCGACCAGTCGGGATCGCAGTGCATCGATTCTGCATTTTGTGGATACAATCACGGCAAC
TGATCGCGAGCTGCTTCTGGAGTACCTGCAACAGCAGGAGGGTAGGAAATGA

Upstream 100 bases:

>100_bases
ATAGTTGACTATTTGATTGAGTTGAACTGTGTCAGTGTATGAAGAGAAAAATGAAGAGAAAAACAGCTGCACATGGTTTC
AAAAGATAAGGAAGTGAAGC

Downstream 100 bases:

>100_bases
CTGCGGCTTCGGCGTTAACTGTAGCGCTCATAATTGGGATTTCACTGGCTGTCATTGGAATTTTTGGTCCTGCGCTTCTT
CGCCACGCAGCGCCAGCGCT

Product: MarR family regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 123; Mature: 122

Protein sequence:

>123_residues
MSIEPGIPTLGPLEEQVMHILWDHGKLTVREVIEFLPGDPAYTTIATVLRHLGRKGMVTTVKDGRTARHSALMNREQYTA
GIMDQVLSTSRDRSASILHFVDTITATDRELLLEYLQQQEGRK

Sequences:

>Translated_123_residues
MSIEPGIPTLGPLEEQVMHILWDHGKLTVREVIEFLPGDPAYTTIATVLRHLGRKGMVTTVKDGRTARHSALMNREQYTA
GIMDQVLSTSRDRSASILHFVDTITATDRELLLEYLQQQEGRK
>Mature_122_residues
SIEPGIPTLGPLEEQVMHILWDHGKLTVREVIEFLPGDPAYTTIATVLRHLGRKGMVTTVKDGRTARHSALMNREQYTAG
IMDQVLSTSRDRSASILHFVDTITATDRELLLEYLQQQEGRK

Specific function: Transcription regulator that binds to an inverted DNA repeat with the consensus sequence 5'-TAC[GT]AC-NNNNN-GT[AC]GTA-3' and regulates genes involved in antibiotic transport, detoxification and cell wall function. Also regulates its own transcription. Bin

COG id: COG3682

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BlaI transcriptional regulatory family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005650
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03965 Pencillinase_R [H]

EC number: NA

Molecular weight: Translated: 13871; Mature: 13740

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIEPGIPTLGPLEEQVMHILWDHGKLTVREVIEFLPGDPAYTTIATVLRHLGRKGMVTT
CCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEE
VKDGRTARHSALMNREQYTAGIMDQVLSTSRDRSASILHFVDTITATDRELLLEYLQQQE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHC
GRK
CCC
>Mature Secondary Structure 
SIEPGIPTLGPLEEQVMHILWDHGKLTVREVIEFLPGDPAYTTIATVLRHLGRKGMVTT
CCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEE
VKDGRTARHSALMNREQYTAGIMDQVLSTSRDRSASILHFVDTITATDRELLLEYLQQQE
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHC
GRK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]