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The map label for this gene is lolC [H]

Identifier: 62185142

GI number: 62185142

Start: 591406

End: 592917

Strand: Direct

Name: lolC [H]

Synonym: CAB514

Alternate gene names: 62185142

Gene position: 591406-592917 (Clockwise)

Preceding gene: 62185141

Following gene: 62185143

Centisome position: 51.68

GC content: 36.77

Gene sequence:

>1512_bases
ATGAAATTAGAACTTCTCATTGCTTTTAAGTATCTAATACCAAGAAGAAAAAGGTTATCTTCTGCCATTGTTTCCATATT
TTCCATAGGCATTATTTCCTTAGTCACTTGGTTATCCATTGTTTTTATTTCTGTTATCTACGGTTTAGAACAACGTTGGA
TTCATGATCTTTCCCAGCTTCATTCTCCAGTGAAAATCCTTCCTTCATCTGTTTATTATGATTCCTATTACTATCAGATA
GACAGACATGCTGACCTTTCTTTGTATACAACAAAGACCATAGGGGAAAAGCTGGCTTCCTCTCTTGTAGATCCCTATGA
CCCAAATGTGGACTACTCCTTACCAGAAAACTTTCCCCTACCAGATAAAACTGCAGATGGAAAATTAAAGGATCCTGTAA
AAATCGCTTTTGAAGTTCTTAATCCCTATCTAGAACAAAATCACGCCCAACTTTTAGAGTTTGAAGAGGGGATTGGCTAT
GTACAAATGGACAGAACGGCCCATCCTAACAAATCAGAATCACGAACATTTTCTCAGTTTATTGCCTATCCTTCTGATGA
AGTGTATAAAAATCGCGTGCTTCCCTATGAACAAACAGATTATAGTTCCGAGATTTTAAACCCTTTTAATAGCTCTGACC
AAGGTTGGGAACAAGATTTTATAAAATTACAAAATACCTATCGAGGAGCTTCGATCATCTTACCTGTGAATTATCGCGAT
ATGGGGTATCGAGTAGGAGATAGGGGAGGGATCAGTATTTTCTCCCCAGAAACTCAGAAAGAAATCCAGCATCCTGTATA
TGTCATAGGCTTCTATAATCCTGGTTTATCTCCTATGGGAAGTAAAATCGTATTTATTGATATGGATCTAGCTTCTCAAA
TACGTTCAGAATCTACGGGAATCGGCATGCATAATGGCTTACATGTCTTCTTTCCCAACACTAAACTGATAACACCAATA
AAAAAGCAAATTGAAACTATCTTAAGTCAAGCCGGTATACAAGAATATTGGGTAGTATCTTCTCTCTATGATTATCAGTA
TTTTAAACCTATTTTAGATCAACTACGTAGTGATCAAGTTCTATTTCTCTTGGTCTCTATCATTATCCTGATCGTCGCTT
GTTCCAATATTGTGACTATGTCTATTCTCTTGGTCAATAATAAGAAGAAAGAAATAGGAATTCTCAAAGCTATGGGGACT
TCTTCTCGTAGCTTAAAAGCTATTTTTGGTCTTTGTGGAGCCTTCTCTGGAGGCATCGGTGTTGTTTTTGGAACAGCTTT
GGCGATTTTAACAATGAAAAATCTCTCAATAATTACTAAAGGCTTAAGTTACTTACAAGGCAGAGAAGCATTTAACTCTA
CTTTCTTCGGTCAAGGTCTTCCTCAAGAAATACATGTGCCGACTATTTTTATGCTAGGTGTAGGCACTTTGGTGTTAGCT
GCTATTTCTGGATTATTACCAGCAAGAAAAGTCGCTAAGATGCATGTCTCTGACATTTTAAAAGCGGAATAA

Upstream 100 bases:

>100_bases
AAATATGATAGAAAACTGCGTAGGCACGTAATTTTCAAAGAAGCTAAGTAAAAAGATTTAATTTACCTGCTAGCTTCTAT
TCCAAGTTGTTGAGTAGGTC

Downstream 100 bases:

>100_bases
TTATGCCTCCTCTTATTCAAGCGAAAAATCTGTCTAAGGTTGTTCTACAAAGCAATCAAGATATCGAAATATTACGTAAT
GTGAACTTTAGCTTACACCC

Product: lipoprotein releasing system transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MKLELLIAFKYLIPRRKRLSSAIVSIFSIGIISLVTWLSIVFISVIYGLEQRWIHDLSQLHSPVKILPSSVYYDSYYYQI
DRHADLSLYTTKTIGEKLASSLVDPYDPNVDYSLPENFPLPDKTADGKLKDPVKIAFEVLNPYLEQNHAQLLEFEEGIGY
VQMDRTAHPNKSESRTFSQFIAYPSDEVYKNRVLPYEQTDYSSEILNPFNSSDQGWEQDFIKLQNTYRGASIILPVNYRD
MGYRVGDRGGISIFSPETQKEIQHPVYVIGFYNPGLSPMGSKIVFIDMDLASQIRSESTGIGMHNGLHVFFPNTKLITPI
KKQIETILSQAGIQEYWVVSSLYDYQYFKPILDQLRSDQVLFLLVSIIILIVACSNIVTMSILLVNNKKKEIGILKAMGT
SSRSLKAIFGLCGAFSGGIGVVFGTALAILTMKNLSIITKGLSYLQGREAFNSTFFGQGLPQEIHVPTIFMLGVGTLVLA
AISGLLPARKVAKMHVSDILKAE

Sequences:

>Translated_503_residues
MKLELLIAFKYLIPRRKRLSSAIVSIFSIGIISLVTWLSIVFISVIYGLEQRWIHDLSQLHSPVKILPSSVYYDSYYYQI
DRHADLSLYTTKTIGEKLASSLVDPYDPNVDYSLPENFPLPDKTADGKLKDPVKIAFEVLNPYLEQNHAQLLEFEEGIGY
VQMDRTAHPNKSESRTFSQFIAYPSDEVYKNRVLPYEQTDYSSEILNPFNSSDQGWEQDFIKLQNTYRGASIILPVNYRD
MGYRVGDRGGISIFSPETQKEIQHPVYVIGFYNPGLSPMGSKIVFIDMDLASQIRSESTGIGMHNGLHVFFPNTKLITPI
KKQIETILSQAGIQEYWVVSSLYDYQYFKPILDQLRSDQVLFLLVSIIILIVACSNIVTMSILLVNNKKKEIGILKAMGT
SSRSLKAIFGLCGAFSGGIGVVFGTALAILTMKNLSIITKGLSYLQGREAFNSTFFGQGLPQEIHVPTIFMLGVGTLVLA
AISGLLPARKVAKMHVSDILKAE
>Mature_503_residues
MKLELLIAFKYLIPRRKRLSSAIVSIFSIGIISLVTWLSIVFISVIYGLEQRWIHDLSQLHSPVKILPSSVYYDSYYYQI
DRHADLSLYTTKTIGEKLASSLVDPYDPNVDYSLPENFPLPDKTADGKLKDPVKIAFEVLNPYLEQNHAQLLEFEEGIGY
VQMDRTAHPNKSESRTFSQFIAYPSDEVYKNRVLPYEQTDYSSEILNPFNSSDQGWEQDFIKLQNTYRGASIILPVNYRD
MGYRVGDRGGISIFSPETQKEIQHPVYVIGFYNPGLSPMGSKIVFIDMDLASQIRSESTGIGMHNGLHVFFPNTKLITPI
KKQIETILSQAGIQEYWVVSSLYDYQYFKPILDQLRSDQVLFLLVSIIILIVACSNIVTMSILLVNNKKKEIGILKAMGT
SSRSLKAIFGLCGAFSGGIGVVFGTALAILTMKNLSIITKGLSYLQGREAFNSTFFGQGLPQEIHVPTIFMLGVGTLVLA
AISGLLPARKVAKMHVSDILKAE

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925
- InterPro:   IPR011926 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 56406; Mature: 56406

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLELLIAFKYLIPRRKRLSSAIVSIFSIGIISLVTWLSIVFISVIYGLEQRWIHDLSQL
CCEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HSPVKILPSSVYYDSYYYQIDRHADLSLYTTKTIGEKLASSLVDPYDPNVDYSLPENFPL
CCCHHHCCCHHEECCEEEEEECCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PDKTADGKLKDPVKIAFEVLNPYLEQNHAQLLEFEEGIGYVQMDRTAHPNKSESRTFSQF
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHH
IAYPSDEVYKNRVLPYEQTDYSSEILNPFNSSDQGWEQDFIKLQNTYRGASIILPVNYRD
HCCCCHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCHH
MGYRVGDRGGISIFSPETQKEIQHPVYVIGFYNPGLSPMGSKIVFIDMDLASQIRSESTG
CCEEECCCCCEEEECCCHHHHHCCCEEEEEEECCCCCCCCCEEEEEECCHHHHHHHCCCC
IGMHNGLHVFFPNTKLITPIKKQIETILSQAGIQEYWVVSSLYDYQYFKPILDQLRSDQV
CCCCCCEEEEECCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
LFLLVSIIILIVACSNIVTMSILLVNNKKKEIGILKAMGTSSRSLKAIFGLCGAFSGGIG
HHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHEEECCCCCHHHHHHHHHHHHHCCCHH
VVFGTALAILTMKNLSIITKGLSYLQGREAFNSTFFGQGLPQEIHVPTIFMLGVGTLVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AISGLLPARKVAKMHVSDILKAE
HHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLELLIAFKYLIPRRKRLSSAIVSIFSIGIISLVTWLSIVFISVIYGLEQRWIHDLSQL
CCEEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HSPVKILPSSVYYDSYYYQIDRHADLSLYTTKTIGEKLASSLVDPYDPNVDYSLPENFPL
CCCHHHCCCHHEECCEEEEEECCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PDKTADGKLKDPVKIAFEVLNPYLEQNHAQLLEFEEGIGYVQMDRTAHPNKSESRTFSQF
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHH
IAYPSDEVYKNRVLPYEQTDYSSEILNPFNSSDQGWEQDFIKLQNTYRGASIILPVNYRD
HCCCCHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCHH
MGYRVGDRGGISIFSPETQKEIQHPVYVIGFYNPGLSPMGSKIVFIDMDLASQIRSESTG
CCEEECCCCCEEEECCCHHHHHCCCEEEEEEECCCCCCCCCEEEEEECCHHHHHHHCCCC
IGMHNGLHVFFPNTKLITPIKKQIETILSQAGIQEYWVVSSLYDYQYFKPILDQLRSDQV
CCCCCCEEEEECCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
LFLLVSIIILIVACSNIVTMSILLVNNKKKEIGILKAMGTSSRSLKAIFGLCGAFSGGIG
HHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHEEECCCCCHHHHHHHHHHHHHCCCHH
VVFGTALAILTMKNLSIITKGLSYLQGREAFNSTFFGQGLPQEIHVPTIFMLGVGTLVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AISGLLPARKVAKMHVSDILKAE
HHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]