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The map label for this gene is ywlC [H]

Identifier: 62185126

GI number: 62185126

Start: 576242

End: 577129

Strand: Direct

Name: ywlC [H]

Synonym: CAB498

Alternate gene names: 62185126

Gene position: 576242-577129 (Clockwise)

Preceding gene: 62185124

Following gene: 62185127

Centisome position: 50.35

GC content: 42.12

Gene sequence:

>888_bases
ATGGTTAATTCTGGAGTTTTTATGTCTGACACAGATCCAGATGTTTTTTTACAACAAGCTGCAGATTATTTAGATCAAGG
CAAGATTGTAGCCTTCCCTACAGATACAGTTTATGGTTTGGGGGTAGCATTAAATTATCCGAATGCCGAAGAGAAAATCT
ACGCTTTAAAGCACCGGGATAGGGGAAAATCGTTGGTCGTGTATGTGAATACTATCGAGGATATGGAAAAATTCTCGGGA
TGTACATTGTCAACACGCGCACTTAAGTTATCACAGAAATTCCTTCCTGGGCCTTTGACTTTGCTCGTTGACCATAAAAA
CCCTAGATTTCACCAAGAGAAACTAGGATTTAGGATTCTTTCTATTCCCATAGTGAACAAGCTCATCGATCTCGCGGGCC
CGCTACTTGGCACTTCTGCAAACATTTCTAATTTCCCTCCAGCAATTACCTCTAATGAAGTGACGGAAGACTTCTCTCAG
GAAGATATTTGTGTGATTCCAGGCTGTTGTTCCTACGGATTAGAGTCTACTGTAGTCTCTGCAGATCCTCTAAAGGTCTA
TCGTGAGGGAATGGTTCCTCGTCAAGTCATCGAAGACGTTGTAGGGGAAAAGGTAGAGACTTGCTTACACACACGTCACG
TATTTTCTCAACACATACAAGTTTATACAGTTAAAGATGAAGATGCTCTCAACAGTTTTCTTGAGAAAAACTCTCGATTT
CAGGGGGTCATCTGCAACAACCCTAAACCACGTGATTTTTACCCTACCCTAAGACAAGCATTAAGATCTGTCGAACCTGT
AGCGGTATTTATCTATGATCCGGAAACATCAGCTTATCCGGAGCTCATCCCCTACCTCATTCCGTATAGTTATACATCCC
CTCGGTGA

Upstream 100 bases:

>100_bases
AGATTCTATATTGAAAAAATTGGATTTAGAAATATGTCTGTGTTAAAGTCTCCTATAAAAATACCACCCATTTCAGTGTT
TTGCAGAGAAATATTAGGGA

Downstream 100 bases:

>100_bases
ACGTCATGATCATAGATATGCACTGCGACCTTCTTTCTCATCCAACTTTTTCCTCTGAGGATCCTTGCGTGCGCTGCTCT
CCAAGTCAATTACTCTCTGG

Product: hypothetical protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MVNSGVFMSDTDPDVFLQQAADYLDQGKIVAFPTDTVYGLGVALNYPNAEEKIYALKHRDRGKSLVVYVNTIEDMEKFSG
CTLSTRALKLSQKFLPGPLTLLVDHKNPRFHQEKLGFRILSIPIVNKLIDLAGPLLGTSANISNFPPAITSNEVTEDFSQ
EDICVIPGCCSYGLESTVVSADPLKVYREGMVPRQVIEDVVGEKVETCLHTRHVFSQHIQVYTVKDEDALNSFLEKNSRF
QGVICNNPKPRDFYPTLRQALRSVEPVAVFIYDPETSAYPELIPYLIPYSYTSPR

Sequences:

>Translated_295_residues
MVNSGVFMSDTDPDVFLQQAADYLDQGKIVAFPTDTVYGLGVALNYPNAEEKIYALKHRDRGKSLVVYVNTIEDMEKFSG
CTLSTRALKLSQKFLPGPLTLLVDHKNPRFHQEKLGFRILSIPIVNKLIDLAGPLLGTSANISNFPPAITSNEVTEDFSQ
EDICVIPGCCSYGLESTVVSADPLKVYREGMVPRQVIEDVVGEKVETCLHTRHVFSQHIQVYTVKDEDALNSFLEKNSRF
QGVICNNPKPRDFYPTLRQALRSVEPVAVFIYDPETSAYPELIPYLIPYSYTSPR
>Mature_295_residues
MVNSGVFMSDTDPDVFLQQAADYLDQGKIVAFPTDTVYGLGVALNYPNAEEKIYALKHRDRGKSLVVYVNTIEDMEKFSG
CTLSTRALKLSQKFLPGPLTLLVDHKNPRFHQEKLGFRILSIPIVNKLIDLAGPLLGTSANISNFPPAITSNEVTEDFSQ
EDICVIPGCCSYGLESTVVSADPLKVYREGMVPRQVIEDVVGEKVETCLHTRHVFSQHIQVYTVKDEDALNSFLEKNSRF
QGVICNNPKPRDFYPTLRQALRSVEPVAVFIYDPETSAYPELIPYLIPYSYTSPR

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=184, Percent_Identity=28.804347826087, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321269, Length=226, Percent_Identity=30.0884955752212, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI78707274, Length=159, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 33045; Mature: 33045

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNSGVFMSDTDPDVFLQQAADYLDQGKIVAFPTDTVYGLGVALNYPNAEEKIYALKHRD
CCCCCEEECCCCHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEEECCCHHHHEEEEEECC
RGKSLVVYVNTIEDMEKFSGCTLSTRALKLSQKFLPGPLTLLVDHKNPRFHQEKLGFRIL
CCCEEEEEEECHHHHHHHCCCCEEHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCEEEE
SIPIVNKLIDLAGPLLGTSANISNFPPAITSNEVTEDFSQEDICVIPGCCSYGLESTVVS
EHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEECCHHHCCCCCCEEC
ADPLKVYREGMVPRQVIEDVVGEKVETCLHTRHVFSQHIQVYTVKDEDALNSFLEKNSRF
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHCCCCE
QGVICNNPKPRDFYPTLRQALRSVEPVAVFIYDPETSAYPELIPYLIPYSYTSPR
EEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MVNSGVFMSDTDPDVFLQQAADYLDQGKIVAFPTDTVYGLGVALNYPNAEEKIYALKHRD
CCCCCEEECCCCHHHHHHHHHHHHHCCCEEEECCCCEEEEEEEEECCCHHHHEEEEEECC
RGKSLVVYVNTIEDMEKFSGCTLSTRALKLSQKFLPGPLTLLVDHKNPRFHQEKLGFRIL
CCCEEEEEEECHHHHHHHCCCCEEHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCEEEE
SIPIVNKLIDLAGPLLGTSANISNFPPAITSNEVTEDFSQEDICVIPGCCSYGLESTVVS
EHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEECCHHHCCCCCCEEC
ADPLKVYREGMVPRQVIEDVVGEKVETCLHTRHVFSQHIQVYTVKDEDALNSFLEKNSRF
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHCCCCE
QGVICNNPKPRDFYPTLRQALRSVEPVAVFIYDPETSAYPELIPYLIPYSYTSPR
EEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]