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The map label for this gene is accA

Identifier: 62184999

GI number: 62184999

Start: 423642

End: 424616

Strand: Direct

Name: accA

Synonym: CAB367

Alternate gene names: 62184999

Gene position: 423642-424616 (Clockwise)

Preceding gene: 62184998

Following gene: 62185000

Centisome position: 37.02

GC content: 44.0

Gene sequence:

>975_bases
ATGGAGCTTCTTCCCCATGAAAAACAAGTCGTAGAGTATGAAAAAACGATAGCAGAGTTTAAGGAAAAAAATAAAAAAAA
TTCTTTACTCTCCTCCTCAGAGATACAAAAATTGGAAAGGCGCTTAGACAAGTTAAAAGAGAAGATCTATGCAGATTTGA
CTCCTTGGGAACGTGTGCAGATATGCCGTCATCCCTCGCGTCCTCGATCAGTGAATTACATTGAAGGCATGTGTGAGGAG
TTTGTAGAGCTTTGTGGAGATCGTACATTTCGTGATGACCCTGCTGTTGTTGGCGGATTAGCGAAGATTCAGGGCCAGAG
ATTTATGCTTATTGGCCAGGAAAAGGGGTGTGATACCTCATCCCGCATGCACAGGAACTTCGGCATGCTCTGCCCCGAAG
GCTTTCGTAAGGCGCTACGTCTTGCAAAAATGGCGGAGAAATTCGGTCTTTCTATTGTCTTTTTGGTGGATACTCCAGGG
GCTTTCCCAGGTCTTACTGCTGAAGAGCGTGGTCAAGGATGGGCGATTGCTAACAATCTTTTCCAATTAGCTAGATTAAA
AACCCCGATTATCGTTCTTGTTATTGGAGAAGGGTGTTCCGGAGGGGCTTTAGGCATGGCGATCGGGGATGTGATTGCGA
TGTTAGAACACTCCTATTATTCTGTAATTTCTCCTGAAGGCTGCGCCTCTATTCTTTGGAAGGATCCGAAAAAGAATAGT
GAAGCGGCTGCTATGTTAAAAATGCATGGTGAGGATCTCAAACAATTTGCTATTGTGGATGTTGTCATTAAGGAGCCGGT
AGGTGGTGCTCACCACAACCCAGCTGCTGTATATCGCGATGTTCGAGATTTTATACTTCGGGAATGGTTACGACTCAAAG
ACCTATCAATAGAAGATTTGTTAGAACAGCGATATCAGAAATTCCGAACTATAGGTCTCTATGAAACTTCTTCTGAAAGC
AGTCCTGAGGCATAA

Upstream 100 bases:

>100_bases
TTATTTTTTTTGAAAATAGAAGAGAAAGTAATCTTATAATTGTTTTTTAAGGATTATTTGTATTAAAATTATCCTTTTTG
TAAGAGGAGAGAATGTTATT

Downstream 100 bases:

>100_bases
AAAGCATCTCACGCTATTAGGTTTTTCTTTGCTTGCCATCTTAGGATTGACCGTGTCGTCTCAAGCAGAGATTTTTTCTC
TAGGTATTATTGCAAAAACA

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MELLPHEKQVVEYEKTIAEFKEKNKKNSLLSSSEIQKLERRLDKLKEKIYADLTPWERVQICRHPSRPRSVNYIEGMCEE
FVELCGDRTFRDDPAVVGGLAKIQGQRFMLIGQEKGCDTSSRMHRNFGMLCPEGFRKALRLAKMAEKFGLSIVFLVDTPG
AFPGLTAEERGQGWAIANNLFQLARLKTPIIVLVIGEGCSGGALGMAIGDVIAMLEHSYYSVISPEGCASILWKDPKKNS
EAAAMLKMHGEDLKQFAIVDVVIKEPVGGAHHNPAAVYRDVRDFILREWLRLKDLSIEDLLEQRYQKFRTIGLYETSSES
SPEA

Sequences:

>Translated_324_residues
MELLPHEKQVVEYEKTIAEFKEKNKKNSLLSSSEIQKLERRLDKLKEKIYADLTPWERVQICRHPSRPRSVNYIEGMCEE
FVELCGDRTFRDDPAVVGGLAKIQGQRFMLIGQEKGCDTSSRMHRNFGMLCPEGFRKALRLAKMAEKFGLSIVFLVDTPG
AFPGLTAEERGQGWAIANNLFQLARLKTPIIVLVIGEGCSGGALGMAIGDVIAMLEHSYYSVISPEGCASILWKDPKKNS
EAAAMLKMHGEDLKQFAIVDVVIKEPVGGAHHNPAAVYRDVRDFILREWLRLKDLSIEDLLEQRYQKFRTIGLYETSSES
SPEA
>Mature_324_residues
MELLPHEKQVVEYEKTIAEFKEKNKKNSLLSSSEIQKLERRLDKLKEKIYADLTPWERVQICRHPSRPRSVNYIEGMCEE
FVELCGDRTFRDDPAVVGGLAKIQGQRFMLIGQEKGCDTSSRMHRNFGMLCPEGFRKALRLAKMAEKFGLSIVFLVDTPG
AFPGLTAEERGQGWAIANNLFQLARLKTPIIVLVIGEGCSGGALGMAIGDVIAMLEHSYYSVISPEGCASILWKDPKKNS
EAAAMLKMHGEDLKQFAIVDVVIKEPVGGAHHNPAAVYRDVRDFILREWLRLKDLSIEDLLEQRYQKFRTIGLYETSSES
SPEA

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=315, Percent_Identity=44.4444444444444, Blast_Score=290, Evalue=1e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_CHLAB (Q5L6A8)

Other databases:

- EMBL:   CR848038
- RefSeq:   YP_219784.1
- ProteinModelPortal:   Q5L6A8
- SMR:   Q5L6A8
- GeneID:   3337970
- GenomeReviews:   CR848038_GR
- KEGG:   cab:CAB367
- HOGENOM:   HBG286557
- OMA:   DRIIPER
- PhylomeDB:   Q5L6A8
- ProtClustDB:   PRK05724
- BioCyc:   CABO218497:CAB367-MONOMER
- BRENDA:   6.4.1.2
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 36521; Mature: 36521

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLPHEKQVVEYEKTIAEFKEKNKKNSLLSSSEIQKLERRLDKLKEKIYADLTPWERVQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ICRHPSRPRSVNYIEGMCEEFVELCGDRTFRDDPAVVGGLAKIQGQRFMLIGQEKGCDTS
HHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCHH
SRMHRNFGMLCPEGFRKALRLAKMAEKFGLSIVFLVDTPGAFPGLTAEERGQGWAIANNL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHCCCCHHHHHHH
FQLARLKTPIIVLVIGEGCSGGALGMAIGDVIAMLEHSYYSVISPEGCASILWKDPKKNS
HHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCH
EAAAMLKMHGEDLKQFAIVDVVIKEPVGGAHHNPAAVYRDVRDFILREWLRLKDLSIEDL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
LEQRYQKFRTIGLYETSSESSPEA
HHHHHHHHHHCCCEECCCCCCCCC
>Mature Secondary Structure
MELLPHEKQVVEYEKTIAEFKEKNKKNSLLSSSEIQKLERRLDKLKEKIYADLTPWERVQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ICRHPSRPRSVNYIEGMCEEFVELCGDRTFRDDPAVVGGLAKIQGQRFMLIGQEKGCDTS
HHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCHH
SRMHRNFGMLCPEGFRKALRLAKMAEKFGLSIVFLVDTPGAFPGLTAEERGQGWAIANNL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHCCCCHHHHHHH
FQLARLKTPIIVLVIGEGCSGGALGMAIGDVIAMLEHSYYSVISPEGCASILWKDPKKNS
HHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCH
EAAAMLKMHGEDLKQFAIVDVVIKEPVGGAHHNPAAVYRDVRDFILREWLRLKDLSIEDL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
LEQRYQKFRTIGLYETSSESSPEA
HHHHHHHHHHCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA