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The map label for this gene is secY [H]

Identifier: 62184755

GI number: 62184755

Start: 116795

End: 118168

Strand: Direct

Name: secY [H]

Synonym: CAB110

Alternate gene names: 62184755

Gene position: 116795-118168 (Clockwise)

Preceding gene: 62184754

Following gene: 62184756

Centisome position: 10.21

GC content: 39.67

Gene sequence:

>1374_bases
ATGACAACTTTACGACAGATATTTTCCATTGCTGAGTTAAGGCAGAAGTTATTTTTTACATTTGCTTTGCTTGCGGCCTG
CCGGATTGGCGTGTTCATTCCTGTTCCAGGAATTAACGGAGAACGCGCTGTAGCCTACTTTAAACAATTACTAGGTTCTA
GCCAGAATTTATTTCAGTTAGCTGATATTTTTTCTGGAGGAGCCTTTGCTCAAATGACGGTTATTGCCTTAGGTGTGGTT
CCCTACATTTCAGCATCCATTATAGTGCAACTTCTCCTAGTATTTATGCCATCTATACAAAGAGAAATGCGGGAAAGCCC
TGATCAAGGTAAAAGAAAGATAGGTAGATTAACTCGTTTATTTACAGTCGGCTTGGCATGTATACAATCGCTGCTTTTTG
CTAAGTTCGCTTTAAAAATGAACATGTCGATTCCTGGTATTGTTCTTCCAACTTTGTTGTCATCTAAATTATTCGGAGCT
CCTTGGATATTCTATCTGACAACAGTTATTGTTATGACAACAGGAACATTGTTGCTCATGTGGATAGGCGAACAGATTTC
TGATAGAGGTATTGGGAATGGTGTCAGCTTAATTATTAGCCTTGGAATTTTAGCTTCGTTTCCATCTGTTTTGGGATCCA
TAGTAAATAAGCTAAACCTGGGTTCGCAAGATCCTTCTCAATTAGGTTTATTCTCACTCTTGTTGCTGTGCTTGATTTTT
GTATTTGTTCTCGTCACAACGATATTGATTATAGAAGGTGTGAGAAAAATTCCCGTGCAATACGCACGTAGAGTAATTGG
TAGGAGAGAAATCCCTGGAGGCGGGTCCTACTTGCCGTTAAAGGTTAACTATGCAGGCGTTATCCCCGTTATTTTTGCTT
CGTCTTTGCTAATGTTTCCTGCGACTATAGGACAATTCATGTCTTCGGATTCTTCGTGGCTTAAGCGAGTCGCTATGATG
TTATCCCCAGGTAGCTGGGTGTATTCTTCATGTTACGTTCTGCTTATCATATTCTTTACTTATTTTTGGACGGCAACACA
GTTCCATCCAGAACAAATTGCTTCTGAAATGAAAAAGAATAATGCCTTTATTCCTGGAATTCGACAAGGGAAGCCTACAC
AAACGTATTTGGAATATACCATGAACCGCGTTACTTTATTAGGAGCGGTGTTCTTAGCTGTTATTGCCATTTTGCCATCT
ATTTTGGGACGCGTTCTTAATGTAGATGCTAATGTGAGTTATTTTTTGGGCGGTACAGCAATGTTGATCGTAGTTGGTGT
GGTTTTGGATACGATGAAACAAGTGGATGCCTTTTTACTTATGCGTCGGTACGATAGTTTTTTGAAAAAAGATCGTTCCA
AAGGAAGGCATTGA

Upstream 100 bases:

>100_bases
AGAAAAAACGTTTATCTGGAAGGACGCTAACGTAGTATTGTCTCAAGGAGTACGAAACCTTATTGGTGTTGCTTAAAGAT
AAGAATTTTCAGGCCCGACT

Downstream 100 bases:

>100_bases
AAAATAACAATTTTTGACCTAAGATGCTTATACTACTTTAAGGGAGGCCCTGCGTATGCCACGCATCATTGGAATTGATA
TTCCTGCGAAGAAAAAACTA

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MTTLRQIFSIAELRQKLFFTFALLAACRIGVFIPVPGINGERAVAYFKQLLGSSQNLFQLADIFSGGAFAQMTVIALGVV
PYISASIIVQLLLVFMPSIQREMRESPDQGKRKIGRLTRLFTVGLACIQSLLFAKFALKMNMSIPGIVLPTLLSSKLFGA
PWIFYLTTVIVMTTGTLLLMWIGEQISDRGIGNGVSLIISLGILASFPSVLGSIVNKLNLGSQDPSQLGLFSLLLLCLIF
VFVLVTTILIIEGVRKIPVQYARRVIGRREIPGGGSYLPLKVNYAGVIPVIFASSLLMFPATIGQFMSSDSSWLKRVAMM
LSPGSWVYSSCYVLLIIFFTYFWTATQFHPEQIASEMKKNNAFIPGIRQGKPTQTYLEYTMNRVTLLGAVFLAVIAILPS
ILGRVLNVDANVSYFLGGTAMLIVVGVVLDTMKQVDAFLLMRRYDSFLKKDRSKGRH

Sequences:

>Translated_457_residues
MTTLRQIFSIAELRQKLFFTFALLAACRIGVFIPVPGINGERAVAYFKQLLGSSQNLFQLADIFSGGAFAQMTVIALGVV
PYISASIIVQLLLVFMPSIQREMRESPDQGKRKIGRLTRLFTVGLACIQSLLFAKFALKMNMSIPGIVLPTLLSSKLFGA
PWIFYLTTVIVMTTGTLLLMWIGEQISDRGIGNGVSLIISLGILASFPSVLGSIVNKLNLGSQDPSQLGLFSLLLLCLIF
VFVLVTTILIIEGVRKIPVQYARRVIGRREIPGGGSYLPLKVNYAGVIPVIFASSLLMFPATIGQFMSSDSSWLKRVAMM
LSPGSWVYSSCYVLLIIFFTYFWTATQFHPEQIASEMKKNNAFIPGIRQGKPTQTYLEYTMNRVTLLGAVFLAVIAILPS
ILGRVLNVDANVSYFLGGTAMLIVVGVVLDTMKQVDAFLLMRRYDSFLKKDRSKGRH
>Mature_456_residues
TTLRQIFSIAELRQKLFFTFALLAACRIGVFIPVPGINGERAVAYFKQLLGSSQNLFQLADIFSGGAFAQMTVIALGVVP
YISASIIVQLLLVFMPSIQREMRESPDQGKRKIGRLTRLFTVGLACIQSLLFAKFALKMNMSIPGIVLPTLLSSKLFGAP
WIFYLTTVIVMTTGTLLLMWIGEQISDRGIGNGVSLIISLGILASFPSVLGSIVNKLNLGSQDPSQLGLFSLLLLCLIFV
FVLVTTILIIEGVRKIPVQYARRVIGRREIPGGGSYLPLKVNYAGVIPVIFASSLLMFPATIGQFMSSDSSWLKRVAMML
SPGSWVYSSCYVLLIIFFTYFWTATQFHPEQIASEMKKNNAFIPGIRQGKPTQTYLEYTMNRVTLLGAVFLAVIAILPSI
LGRVLNVDANVSYFLGGTAMLIVVGVVLDTMKQVDAFLLMRRYDSFLKKDRSKGRH

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=448, Percent_Identity=38.8392857142857, Blast_Score=274, Evalue=7e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 50420; Mature: 50289

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00755 SECY_1 ; PS00756 SECY_2 ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTLRQIFSIAELRQKLFFTFALLAACRIGVFIPVPGINGERAVAYFKQLLGSSQNLFQL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHCCCCHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]