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The map label for this gene is sufC [H]

Identifier: 62184699

GI number: 62184699

Start: 66010

End: 66777

Strand: Direct

Name: sufC [H]

Synonym: CAB052

Alternate gene names: 62184699

Gene position: 66010-66777 (Clockwise)

Preceding gene: 62184698

Following gene: 62184700

Centisome position: 5.77

GC content: 39.71

Gene sequence:

>768_bases
ATGCTACATATACAAAACTTACACGTATGTTGTGAGGATGTTAAAATCCTGGATTATTTAAATTTGCATATTCATCCGGG
GGAATTACATATAATTATGGGCCCTAATGGAGCAGGAAAATCTACCTTCGCGAAAGTGTTATCAGGAGATGATAGTTTAT
CTATCATTTCTGGAGAAATAAGCTTATTGGGTCAGGATCTTTTAGAAAAAGCGCCTGAAGAGCGAGCTCATATGGGATTG
TTTATAGGATTCCAACAACCTCCAGAAATTCCTGGGGTGAATAATAAGCTTTTTCTAAAAGATGCTTACAATGCTTGTAG
GCGTTCTCGGCAAGAAGAAGAGATGGCAGAAGCTGAATTCGATATGTTATTGTCCTCTGTATCGGAGACTTATGAATTCG
CATCCTTTCAGCATTTCTTACAAAGAAATATCAACGAAGGATTTTCCGGAGGAGAGAGAAAGAAAAACGAAATTTGGCAA
ATGCTTGTTCTAGAACCGGAAATGATACTGTTAGATGAGCCTGATTCCGGGTTGGACGTTGATGCTTTAAGATTCATATG
TAAAACCATTGAGAAATATCGCGAACTTCATCCTAAAAGTGCCACCTGCATAGTTACACATAACCCTAAGTTGGGCAGTC
TTCTTGAGCCTGACCACGTACATATTCTTTTAGAAGGCAAGATAGCCTGTTCGGGAGGGGTTTCGTTAATGCAGGAGTTA
GAAGAAAAGAGTTATCACGAAGTCTTGGCACGCTCTTCTTGGGGGTAA

Upstream 100 bases:

>100_bases
CGGTTTTTGCCTTGAAATTATCGAACAGTTACCTTTAGAGTTTGCTCGAGAAGCTTCAAAATTATTGTTTGTTAAGTTGG
AAAATAGCGTGGGGTAGTTG

Downstream 100 bases:

>100_bases
ATATGTTAGGTTTTTTGGAGCATACCTTTCCTATAGTTAAGGATTCTCCTATTCATCAAGCGGCACAAGCATACTATGAG
AAATACTCTCAGTTAGAGTC

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MLHIQNLHVCCEDVKILDYLNLHIHPGELHIIMGPNGAGKSTFAKVLSGDDSLSIISGEISLLGQDLLEKAPEERAHMGL
FIGFQQPPEIPGVNNKLFLKDAYNACRRSRQEEEMAEAEFDMLLSSVSETYEFASFQHFLQRNINEGFSGGERKKNEIWQ
MLVLEPEMILLDEPDSGLDVDALRFICKTIEKYRELHPKSATCIVTHNPKLGSLLEPDHVHILLEGKIACSGGVSLMQEL
EEKSYHEVLARSSWG

Sequences:

>Translated_255_residues
MLHIQNLHVCCEDVKILDYLNLHIHPGELHIIMGPNGAGKSTFAKVLSGDDSLSIISGEISLLGQDLLEKAPEERAHMGL
FIGFQQPPEIPGVNNKLFLKDAYNACRRSRQEEEMAEAEFDMLLSSVSETYEFASFQHFLQRNINEGFSGGERKKNEIWQ
MLVLEPEMILLDEPDSGLDVDALRFICKTIEKYRELHPKSATCIVTHNPKLGSLLEPDHVHILLEGKIACSGGVSLMQEL
EEKSYHEVLARSSWG
>Mature_255_residues
MLHIQNLHVCCEDVKILDYLNLHIHPGELHIIMGPNGAGKSTFAKVLSGDDSLSIISGEISLLGQDLLEKAPEERAHMGL
FIGFQQPPEIPGVNNKLFLKDAYNACRRSRQEEEMAEAEFDMLLSSVSETYEFASFQHFLQRNINEGFSGGERKKNEIWQ
MLVLEPEMILLDEPDSGLDVDALRFICKTIEKYRELHPKSATCIVTHNPKLGSLLEPDHVHILLEGKIACSGGVSLMQEL
EEKSYHEVLARSSWG

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787972, Length=245, Percent_Identity=44.4897959183673, Blast_Score=222, Evalue=2e-59,
Organism=Escherichia coli, GI1790467, Length=234, Percent_Identity=29.0598290598291, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87081791, Length=179, Percent_Identity=28.4916201117318, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081782, Length=221, Percent_Identity=27.6018099547511, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786698, Length=209, Percent_Identity=28.7081339712919, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI87081709, Length=196, Percent_Identity=26.0204081632653, Blast_Score=61, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24581407, Length=234, Percent_Identity=31.1965811965812, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI45552199, Length=234, Percent_Identity=31.1965811965812, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 28668; Mature: 28668

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHIQNLHVCCEDVKILDYLNLHIHPGELHIIMGPNGAGKSTFAKVLSGDDSLSIISGEI
CCEECHHHHHHHHHHHHHHEEEEEECCEEEEEECCCCCCHHHHHHHHCCCCCEEEEEHHH
SLLGQDLLEKAPEERAHMGLFIGFQQPPEIPGVNNKLFLKDAYNACRRSRQEEEMAEAEF
HHHHHHHHHHCCHHHHHEEEEEECCCCCCCCCCCCEEEHHHHHHHHHHCHHHHHHHHHHH
DMLLSSVSETYEFASFQHFLQRNINEGFSGGERKKNEIWQMLVLEPEMILLDEPDSGLDV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEECCCEEEEECCCCCCCH
DALRFICKTIEKYRELHPKSATCIVTHNPKLGSLLEPDHVHILLEGKIACSGGVSLMQEL
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCEEECCCHHHHHHH
EEKSYHEVLARSSWG
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MLHIQNLHVCCEDVKILDYLNLHIHPGELHIIMGPNGAGKSTFAKVLSGDDSLSIISGEI
CCEECHHHHHHHHHHHHHHEEEEEECCEEEEEECCCCCCHHHHHHHHCCCCCEEEEEHHH
SLLGQDLLEKAPEERAHMGLFIGFQQPPEIPGVNNKLFLKDAYNACRRSRQEEEMAEAEF
HHHHHHHHHHCCHHHHHEEEEEECCCCCCCCCCCCEEEHHHHHHHHHHCHHHHHHHHHHH
DMLLSSVSETYEFASFQHFLQRNINEGFSGGERKKNEIWQMLVLEPEMILLDEPDSGLDV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHEECCCEEEEECCCCCCCH
DALRFICKTIEKYRELHPKSATCIVTHNPKLGSLLEPDHVHILLEGKIACSGGVSLMQEL
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCEEECCCHHHHHHH
EEKSYHEVLARSSWG
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]