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The map label for this gene is yscN [H]

Identifier: 62184683

GI number: 62184683

Start: 44048

End: 45376

Strand: Direct

Name: yscN [H]

Synonym: CAB036

Alternate gene names: 62184683

Gene position: 44048-45376 (Clockwise)

Preceding gene: 62184682

Following gene: 62184684

Centisome position: 3.85

GC content: 46.43

Gene sequence:

>1329_bases
ATGGACGAATTGACGACAGATTTCGATACCCTCATGTCGCAATTGAACGACGTACACTTGACTACCGTTGTCGGTCGTAT
AACTGAAGTCGTCGGTATGTTAATTAAAGCTGTCGTTCCCAATGTACGCGTTGGGGAGGTATGCTTAGTTAAACGTTATG
GTATGGAGCCGCTCGTGACCGAAGTCGTCGGCTTCACACAAAATTTCGCTTTTTTATCGCCACTAGGAGAACTTACTGGA
GTCAGCCCTTCTTCAGAGGTTATTCCCACAGGTCTGCCTTTGTATATCCGTGCAGGTAACGGTCTTTTAGGTCGTGTATT
GAATGGTCTGGGAGAACCTATCGACTCCGAGATCAAAGGACCTTTGGTTGATGTTAACGAAACCTACCCTGTGTTTCGCG
CTCCACCAGATCCATTGCATAGAGAAAAATTAAGAACAATTTTATCCACCGGCGTGCGGTGTATCGACGGTATGCTCACA
GTCGCCAGAGGCCAGCGTATAGGCATTTTTGCTGGAGCTGGGGTGGGTAAATCGTCTCTCTTGGGAATGATCGCTAGAAA
CGCGGAAGAAGCCGATGTCAATGTGATTGCTCTCATCGGAGAGCGGGGCCGAGAGGTTCGTGAATTTATCGAGGGCGATC
TCGGAGAAGAAGGAATGAAACGTTCGGTGATCGTCGTCTCTACTTCAGATCAATCCTCACAGTTGCGATTAAATGCTGCT
TACGTAGGCACCGCTATAGCAGAGTATTTTCGTGATCAGGGCAAAACCGTAGTTTTGATGATGGATTCTGTCACCCGATT
TGCCCGAGCCCTAAGAGAAGTCGGTCTAGCTGCCGGAGAACCGCCAGCTCGAGGAGGATACACACCTTCTGTATTCTCAA
CTTTGCCTAGGTTATTAGAACGTTCCGGAGCTTCGGATAAAGGAACAATCACAGCCTTTTACACAGTACTTGTTGCCGGG
GATGATATGAATGAACCGGTCGCTGATGAAGTTAAATCGATTCTTGATGGTCACGTTGTCTTGTCTAACGCTTTAGCTCA
GGCATACCATTATCCTGCTATTGATGTCTTAGCATCTATCAGCCGATTGCTGACAGCAATTGTTCCTGAGGAACAACGAC
GCATCATAGGAAAAGCCCGAGAGGTGCTGGCAAAATACAAAGCAAACGAAATGCTTATACGTATTGGAGAATATCGCCGA
GGGTCCGATCGTGAAGTGGATTTTGCTATAGATCACATTGATAAATTGAACAGATTCTTAAAGCAAGATATTCATGAAAA
AACAAATTACGAGGAAGCCTCGCAACAGCTTCGGGCTATTTTCCGATAA

Upstream 100 bases:

>100_bases
GCTGTTCAAAGAGCAACGCAAAGAGCAGAACTTTTTGCTAGTATCGTAGGAACTACGGTAAGTAGTATAAAGACGATAAT
GACCACACAATTAGGTTAAC

Downstream 100 bases:

>100_bases
GATATTCAGGGTAAAATGCCGTGCCTAAATACCCGTTAGAACCTGTTCTAGCGATTAAAAGAGATCGTGTTGATAGAGCA
GAAAAAATCGTTAAGGAACA

Product: type III secretion system ATPase

Products: NA

Alternate protein names: Yop proteins secretion ATPase [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MDELTTDFDTLMSQLNDVHLTTVVGRITEVVGMLIKAVVPNVRVGEVCLVKRYGMEPLVTEVVGFTQNFAFLSPLGELTG
VSPSSEVIPTGLPLYIRAGNGLLGRVLNGLGEPIDSEIKGPLVDVNETYPVFRAPPDPLHREKLRTILSTGVRCIDGMLT
VARGQRIGIFAGAGVGKSSLLGMIARNAEEADVNVIALIGERGREVREFIEGDLGEEGMKRSVIVVSTSDQSSQLRLNAA
YVGTAIAEYFRDQGKTVVLMMDSVTRFARALREVGLAAGEPPARGGYTPSVFSTLPRLLERSGASDKGTITAFYTVLVAG
DDMNEPVADEVKSILDGHVVLSNALAQAYHYPAIDVLASISRLLTAIVPEEQRRIIGKAREVLAKYKANEMLIRIGEYRR
GSDREVDFAIDHIDKLNRFLKQDIHEKTNYEEASQQLRAIFR

Sequences:

>Translated_442_residues
MDELTTDFDTLMSQLNDVHLTTVVGRITEVVGMLIKAVVPNVRVGEVCLVKRYGMEPLVTEVVGFTQNFAFLSPLGELTG
VSPSSEVIPTGLPLYIRAGNGLLGRVLNGLGEPIDSEIKGPLVDVNETYPVFRAPPDPLHREKLRTILSTGVRCIDGMLT
VARGQRIGIFAGAGVGKSSLLGMIARNAEEADVNVIALIGERGREVREFIEGDLGEEGMKRSVIVVSTSDQSSQLRLNAA
YVGTAIAEYFRDQGKTVVLMMDSVTRFARALREVGLAAGEPPARGGYTPSVFSTLPRLLERSGASDKGTITAFYTVLVAG
DDMNEPVADEVKSILDGHVVLSNALAQAYHYPAIDVLASISRLLTAIVPEEQRRIIGKAREVLAKYKANEMLIRIGEYRR
GSDREVDFAIDHIDKLNRFLKQDIHEKTNYEEASQQLRAIFR
>Mature_442_residues
MDELTTDFDTLMSQLNDVHLTTVVGRITEVVGMLIKAVVPNVRVGEVCLVKRYGMEPLVTEVVGFTQNFAFLSPLGELTG
VSPSSEVIPTGLPLYIRAGNGLLGRVLNGLGEPIDSEIKGPLVDVNETYPVFRAPPDPLHREKLRTILSTGVRCIDGMLT
VARGQRIGIFAGAGVGKSSLLGMIARNAEEADVNVIALIGERGREVREFIEGDLGEEGMKRSVIVVSTSDQSSQLRLNAA
YVGTAIAEYFRDQGKTVVLMMDSVTRFARALREVGLAAGEPPARGGYTPSVFSTLPRLLERSGASDKGTITAFYTVLVAG
DDMNEPVADEVKSILDGHVVLSNALAQAYHYPAIDVLASISRLLTAIVPEEQRRIIGKAREVLAKYKANEMLIRIGEYRR
GSDREVDFAIDHIDKLNRFLKQDIHEKTNYEEASQQLRAIFR

Specific function: Is a component of the Yop secretion machinery using ATP, and it is either the energizer of this machinery, or part of it [H]

COG id: COG1157

COG function: function code NU; Flagellar biosynthesis/type III secretory pathway ATPase

Gene ontology:

Cell location: Cytoplasm. Note=But connected to the inner membrane possibly through LcrD (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=353, Percent_Identity=32.0113314447592, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI19913428, Length=290, Percent_Identity=30, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI50345984, Length=311, Percent_Identity=28.9389067524116, Blast_Score=119, Evalue=8e-27,
Organism=Homo sapiens, GI4757810, Length=311, Percent_Identity=28.9389067524116, Blast_Score=119, Evalue=8e-27,
Organism=Homo sapiens, GI19913426, Length=289, Percent_Identity=29.0657439446367, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI19913424, Length=236, Percent_Identity=30.5084745762712, Blast_Score=105, Evalue=9e-23,
Organism=Escherichia coli, GI1788251, Length=451, Percent_Identity=45.8980044345898, Blast_Score=349, Evalue=2e-97,
Organism=Escherichia coli, GI1790170, Length=408, Percent_Identity=30.8823529411765, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1790172, Length=365, Percent_Identity=29.3150684931507, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1790217, Length=332, Percent_Identity=28.3132530120482, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI25144756, Length=347, Percent_Identity=33.1412103746398, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI71988063, Length=356, Percent_Identity=27.247191011236, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71988080, Length=356, Percent_Identity=27.247191011236, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17510931, Length=287, Percent_Identity=29.2682926829268, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17570191, Length=329, Percent_Identity=26.4437689969605, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71988074, Length=336, Percent_Identity=26.1904761904762, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17565854, Length=326, Percent_Identity=27.9141104294479, Blast_Score=109, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6322581, Length=431, Percent_Identity=30.6264501160093, Blast_Score=169, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6319370, Length=431, Percent_Identity=27.6102088167053, Blast_Score=133, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6319603, Length=377, Percent_Identity=28.3819628647215, Blast_Score=123, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6320016, Length=188, Percent_Identity=34.5744680851064, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24638766, Length=353, Percent_Identity=32.5779036827195, Blast_Score=165, Evalue=5e-41,
Organism=Drosophila melanogaster, GI28574560, Length=348, Percent_Identity=31.8965517241379, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24658560, Length=311, Percent_Identity=29.903536977492, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI281361666, Length=302, Percent_Identity=28.1456953642384, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24646341, Length=302, Percent_Identity=28.1456953642384, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI17136796, Length=302, Percent_Identity=28.1456953642384, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24583992, Length=257, Percent_Identity=29.9610894941634, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24583988, Length=257, Percent_Identity=29.9610894941634, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24583986, Length=257, Percent_Identity=29.9610894941634, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24583984, Length=257, Percent_Identity=29.9610894941634, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI20129479, Length=256, Percent_Identity=30.46875, Blast_Score=105, Evalue=5e-23,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR004100
- InterPro:   IPR005714
- InterPro:   IPR013380 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 48283; Mature: 48283

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDELTTDFDTLMSQLNDVHLTTVVGRITEVVGMLIKAVVPNVRVGEVCLVKRYGMEPLVT
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHH
EVVGFTQNFAFLSPLGELTGVSPSSEVIPTGLPLYIRAGNGLLGRVLNGLGEPIDSEIKG
HHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCHHCCC
PLVDVNETYPVFRAPPDPLHREKLRTILSTGVRCIDGMLTVARGQRIGIFAGAGVGKSSL
CEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
LGMIARNAEEADVNVIALIGERGREVREFIEGDLGEEGMKRSVIVVSTSDQSSQLRLNAA
HHHHHCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEHHH
YVGTAIAEYFRDQGKTVVLMMDSVTRFARALREVGLAAGEPPARGGYTPSVFSTLPRLLE
HHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
RSGASDKGTITAFYTVLVAGDDMNEPVADEVKSILDGHVVLSNALAQAYHYPAIDVLASI
HCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHH
SRLLTAIVPEEQRRIIGKAREVLAKYKANEMLIRIGEYRRGSDREVDFAIDHIDKLNRFL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHH
KQDIHEKTNYEEASQQLRAIFR
HHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure
MDELTTDFDTLMSQLNDVHLTTVVGRITEVVGMLIKAVVPNVRVGEVCLVKRYGMEPLVT
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHH
EVVGFTQNFAFLSPLGELTGVSPSSEVIPTGLPLYIRAGNGLLGRVLNGLGEPIDSEIKG
HHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCHHCCC
PLVDVNETYPVFRAPPDPLHREKLRTILSTGVRCIDGMLTVARGQRIGIFAGAGVGKSSL
CEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
LGMIARNAEEADVNVIALIGERGREVREFIEGDLGEEGMKRSVIVVSTSDQSSQLRLNAA
HHHHHCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEHHH
YVGTAIAEYFRDQGKTVVLMMDSVTRFARALREVGLAAGEPPARGGYTPSVFSTLPRLLE
HHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
RSGASDKGTITAFYTVLVAGDDMNEPVADEVKSILDGHVVLSNALAQAYHYPAIDVLASI
HCCCCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHH
SRLLTAIVPEEQRRIIGKAREVLAKYKANEMLIRIGEYRRGSDREVDFAIDHIDKLNRFL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHH
KQDIHEKTNYEEASQQLRAIFR
HHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8132449; 2160939 [H]