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The map label for this gene is ykoW [H]

Identifier: 59714259

GI number: 59714259

Start: 1214785

End: 1215498

Strand: Reverse

Name: ykoW [H]

Synonym: VF_A1076

Alternate gene names: 59714259

Gene position: 1215498-1214785 (Counterclockwise)

Preceding gene: 59714261

Following gene: 59714258

Centisome position: 91.37

GC content: 26.19

Gene sequence:

>714_bases
ATGTTCTCAATTAAGAAATTGGTTAATTTTATGTATTCAAAAGTATTCTTTCTATATCAACCAAAGTTTTACTATGGTGA
ATTATGTGCTTATGAGGCTCTATTAAGAGGTGTATTTTATGAAGGAAGTATTATTTACTACCAAGAGCTAATGAGTAAGC
ATAAAAAAGATTTATTTTTTAATTATTTCATTATAAATAAAGTAATAAGTGATTTAGTCAAGCTTAATTGTTCTGGAATT
AGAAAACATCCAGTTTCCATAAATATAAGTGCTAAATTTATATCGACATTAATCGATGTTGGACAACTTGATCTACAAAA
AATAAATTCATTTAACCTTAAATTAGAGTTTAATATTACGGAAGATGAAAAAATAAATGATTTTGATGTTTGTAATAAAA
ACATTTCATTACTTTCCTCATTTGGCATATCAGTTAGTTTAGTTGACTTTAGTGCAGGAATTAGTTCATTAGAGCGCCTT
TCATATTTGAATAATATTAAGTTTGTCAAATTAGATAAAAGTTTAACTGATAATATCGAAAACAACCCTTCACAGCTATT
TCAACTAGAAACTATATATAGGCTTATTAAAGAGTTCAAATTTGAAGTGATAGCTAAAGATGTAGAAACACAAGATGCTT
ATTACTTATTAATCCAATTAGGTATTGGTTACTTTCAGGGTTTTAAATTTGGAAGACCGCTACTTATTCCTTAA

Upstream 100 bases:

>100_bases
TACTACTGTGAAATAGTTTATTTAAATTAATTATAAAGTGAATTAATTTGGCTAGGTCAGGATATATTATCCGTTTTGTT
AATTATAATTATGAATTTTA

Downstream 100 bases:

>100_bases
AATAAAATTATTTATGTATGATTAAACTTAAAAATATCCTTCGTAATTTTGACCGATATAGAAGAACTAAGATGGCAGTT
TTGGAGCCCTTATTATATCG

Product: EAL domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MFSIKKLVNFMYSKVFFLYQPKFYYGELCAYEALLRGVFYEGSIIYYQELMSKHKKDLFFNYFIINKVISDLVKLNCSGI
RKHPVSINISAKFISTLIDVGQLDLQKINSFNLKLEFNITEDEKINDFDVCNKNISLLSSFGISVSLVDFSAGISSLERL
SYLNNIKFVKLDKSLTDNIENNPSQLFQLETIYRLIKEFKFEVIAKDVETQDAYYLLIQLGIGYFQGFKFGRPLLIP

Sequences:

>Translated_237_residues
MFSIKKLVNFMYSKVFFLYQPKFYYGELCAYEALLRGVFYEGSIIYYQELMSKHKKDLFFNYFIINKVISDLVKLNCSGI
RKHPVSINISAKFISTLIDVGQLDLQKINSFNLKLEFNITEDEKINDFDVCNKNISLLSSFGISVSLVDFSAGISSLERL
SYLNNIKFVKLDKSLTDNIENNPSQLFQLETIYRLIKEFKFEVIAKDVETQDAYYLLIQLGIGYFQGFKFGRPLLIP
>Mature_237_residues
MFSIKKLVNFMYSKVFFLYQPKFYYGELCAYEALLRGVFYEGSIIYYQELMSKHKKDLFFNYFIINKVISDLVKLNCSGI
RKHPVSINISAKFISTLIDVGQLDLQKINSFNLKLEFNITEDEKINDFDVCNKNISLLSSFGISVSLVDFSAGISSLERL
SYLNNIKFVKLDKSLTDNIENNPSQLFQLETIYRLIKEFKFEVIAKDVETQDAYYLLIQLGIGYFQGFKFGRPLLIP

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=222, Percent_Identity=27.9279279279279, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI226510982, Length=233, Percent_Identity=25.3218884120172, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082096, Length=117, Percent_Identity=32.4786324786325, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790496, Length=209, Percent_Identity=26.7942583732057, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 27543; Mature: 27543

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSIKKLVNFMYSKVFFLYQPKFYYGELCAYEALLRGVFYEGSIIYYQELMSKHKKDLFF
CCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
NYFIINKVISDLVKLNCSGIRKHPVSINISAKFISTLIDVGQLDLQKINSFNLKLEFNIT
HHHHHHHHHHHHHHCCCCCCEECCEEEEEHHHHHHHHHHHCCHHHHHCCCEEEEEEEEEC
EDEKINDFDVCNKNISLLSSFGISVSLVDFSAGISSLERLSYLNNIKFVKLDKSLTDNIE
CCCCCCHHHHCCCCHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCCCEEEEECCHHHCCCC
NNPSQLFQLETIYRLIKEFKFEVIAKDVETQDAYYLLIQLGIGYFQGFKFGRPLLIP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFSIKKLVNFMYSKVFFLYQPKFYYGELCAYEALLRGVFYEGSIIYYQELMSKHKKDLFF
CCCHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
NYFIINKVISDLVKLNCSGIRKHPVSINISAKFISTLIDVGQLDLQKINSFNLKLEFNIT
HHHHHHHHHHHHHHCCCCCCEECCEEEEEHHHHHHHHHHHCCHHHHHCCCEEEEEEEEEC
EDEKINDFDVCNKNISLLSSFGISVSLVDFSAGISSLERLSYLNNIKFVKLDKSLTDNIE
CCCCCCHHHHCCCCHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCCCEEEEECCHHHCCCC
NNPSQLFQLETIYRLIKEFKFEVIAKDVETQDAYYLLIQLGIGYFQGFKFGRPLLIP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]