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The map label for this gene is aer [H]

Identifier: 59714254

GI number: 59714254

Start: 1207108

End: 1208637

Strand: Reverse

Name: aer [H]

Synonym: VF_A1071

Alternate gene names: 59714254

Gene position: 1208637-1207108 (Counterclockwise)

Preceding gene: 59714258

Following gene: 59714253

Centisome position: 90.85

GC content: 29.41

Gene sequence:

>1530_bases
ATGGATAATAATGAAATAATATTTAAATCTACAGAACAATTAGTTTCAATTACTGATTTAGAAGGGAGGATTACTTATGC
TAATGAGGCTTTTTGTTTGATCTCAGGCTACAAAGTAGATGAGTTAAAAGGTCAAAATCATAACATCATTAGACATCCTT
TTATGCCTAAATTGGCATTCGAAGATTTGTGGTCAAAATTAAAAGAAGGAAAAGCTTGGCGCGGCATCGTAATTAATCGT
TGCAAAAATGGTGATTACTATTGGGTGGATGCATATATTACTTCAATCTTAAAAGATAATAATGTTATTGGTTATCAATC
TGTTCGTACCGTGCCAACTCAAAAGCAAAAGGAAAAAGCTAAAAGGTTATATGAGCATCTTAATAAAGGTGGTTCTATTT
ATGATTTTCAATCTGATATAGTTCTACGAAGAGTTATAGCTTTATTTATAATTAGCATAGCTATCACTATATTATTTTTT
ATCAATGATTCAGTTACTACACCTTTAATTGTTATAAGCTTACTAATTTGTATTGGTGCCATTTTTAATCAAGAATTATT
TACCTTTCCTTCTTATGCTAAAAAAGTGAAAATTTTATTTGATAGCCCTTCACGTCATATTTTTTCTGGAGGAGGATTTA
TTGGTATTGTCGATTATCAGACGAAATTAAATAATGCTAGAATTCGAACGATACTTGGTCGAAGTTCAGATTCAGGACAT
GCATTATTAAGCGTTGTTTCTGAATTAAAGAATTCAGCTAGTGATATTATTAATGGTGTTGAAGAAGAAAATAAAAATTT
AAAACAATCAGTAACTGCTATTACTGAAATGACAACTAATCTTCAAGAAGTTAGCATCAATGTAAATCAAGTATATGAAT
CAGTAAGAGTTGCAATTAATGAGAGCGAGAAAAGTTCTATTTATTTAGGCTCATCTATGGATAAAGTTAATAATTTATCT
ATAAATATCGATAAATTAGCAGGAAATGCAATAAATTTAATTGAAGACATAAATAAGATTTCTATTATTATGACTGATAT
TCAAAGTATTGCTGAACAAACGAATTTATTAGCTCTTAATGCTGCAATTGAAGCTGCACGAGCTGGAGAACAAGGGCGAG
GTTTTGCTGTTGTTGCTGATGAAGTTAGAACTCTTGCTAATCGAACACAAAAAGCATCGTTGATAATTCAAAACTCTGTT
ACCGATCTAAAAAAAATATTAACTATATGGAGTGATGAAATGTTTATTAGTAAAAAAGAAGCCAATGATTGCTCTGATCG
AAGTAGTAAAGTTAATCAAGCAATGAATAATATTCTTAATCAAATTAATAAAATTGGAGATCAAGCTTCTCAAATTGCAT
TAACTATCGAAGATCAAGAAAATATATCTAAAGAAATAAGTCAAGGTATTCATCAAGTAAAAGGCCTTTCTCAAAAGAAT
GCTACCCAAGGAAATAAAATACTTGACTATGCCAATAAAGTTGATAGCGCAACAATGAAAATATTAGATATTAGCAAGAT
ATTCAAATAA

Upstream 100 bases:

>100_bases
ATGTTTTAAAATCGATAAACTTGTGATAGAAATAGAAAATAATTTTATAATATACTCATTAAACCAATGGTTTAGTGTTT
TTCAATTTTATAAGTATTGT

Downstream 100 bases:

>100_bases
GTATAACTATCTCTATAAATTTTTTTAGTAAAAATAAGCTGTAATTTGTAGATTTACATAATTTTAAGTTGGTATAAAAA
TGAGAAGAAGCGTTCGATTT

Product: methyl-accepting chemotaxis protein, putative aerotaxis receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MDNNEIIFKSTEQLVSITDLEGRITYANEAFCLISGYKVDELKGQNHNIIRHPFMPKLAFEDLWSKLKEGKAWRGIVINR
CKNGDYYWVDAYITSILKDNNVIGYQSVRTVPTQKQKEKAKRLYEHLNKGGSIYDFQSDIVLRRVIALFIISIAITILFF
INDSVTTPLIVISLLICIGAIFNQELFTFPSYAKKVKILFDSPSRHIFSGGGFIGIVDYQTKLNNARIRTILGRSSDSGH
ALLSVVSELKNSASDIINGVEEENKNLKQSVTAITEMTTNLQEVSINVNQVYESVRVAINESEKSSIYLGSSMDKVNNLS
INIDKLAGNAINLIEDINKISIIMTDIQSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLANRTQKASLIIQNSV
TDLKKILTIWSDEMFISKKEANDCSDRSSKVNQAMNNILNQINKIGDQASQIALTIEDQENISKEISQGIHQVKGLSQKN
ATQGNKILDYANKVDSATMKILDISKIFK

Sequences:

>Translated_509_residues
MDNNEIIFKSTEQLVSITDLEGRITYANEAFCLISGYKVDELKGQNHNIIRHPFMPKLAFEDLWSKLKEGKAWRGIVINR
CKNGDYYWVDAYITSILKDNNVIGYQSVRTVPTQKQKEKAKRLYEHLNKGGSIYDFQSDIVLRRVIALFIISIAITILFF
INDSVTTPLIVISLLICIGAIFNQELFTFPSYAKKVKILFDSPSRHIFSGGGFIGIVDYQTKLNNARIRTILGRSSDSGH
ALLSVVSELKNSASDIINGVEEENKNLKQSVTAITEMTTNLQEVSINVNQVYESVRVAINESEKSSIYLGSSMDKVNNLS
INIDKLAGNAINLIEDINKISIIMTDIQSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLANRTQKASLIIQNSV
TDLKKILTIWSDEMFISKKEANDCSDRSSKVNQAMNNILNQINKIGDQASQIALTIEDQENISKEISQGIHQVKGLSQKN
ATQGNKILDYANKVDSATMKILDISKIFK
>Mature_509_residues
MDNNEIIFKSTEQLVSITDLEGRITYANEAFCLISGYKVDELKGQNHNIIRHPFMPKLAFEDLWSKLKEGKAWRGIVINR
CKNGDYYWVDAYITSILKDNNVIGYQSVRTVPTQKQKEKAKRLYEHLNKGGSIYDFQSDIVLRRVIALFIISIAITILFF
INDSVTTPLIVISLLICIGAIFNQELFTFPSYAKKVKILFDSPSRHIFSGGGFIGIVDYQTKLNNARIRTILGRSSDSGH
ALLSVVSELKNSASDIINGVEEENKNLKQSVTAITEMTTNLQEVSINVNQVYESVRVAINESEKSSIYLGSSMDKVNNLS
INIDKLAGNAINLIEDINKISIIMTDIQSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLANRTQKASLIIQNSV
TDLKKILTIWSDEMFISKKEANDCSDRSSKVNQAMNNILNQINKIGDQASQIALTIEDQENISKEISQGIHQVKGLSQKN
ATQGNKILDYANKVDSATMKILDISKIFK

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=510, Percent_Identity=29.8039215686275, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1787690, Length=250, Percent_Identity=29.6, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788195, Length=270, Percent_Identity=29.6296296296296, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788194, Length=240, Percent_Identity=28.3333333333333, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI2367378, Length=247, Percent_Identity=31.9838056680162, Blast_Score=86, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 56742; Mature: 56742

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNNEIIFKSTEQLVSITDLEGRITYANEAFCLISGYKVDELKGQNHNIIRHPFMPKLAF
CCCCCEEEECHHHHEEEECCCCEEEECCCEEEEEECCEEHHCCCCCCCEEECCCCCHHHH
EDLWSKLKEGKAWRGIVINRCKNGDYYWVDAYITSILKDNNVIGYQSVRTVPTQKQKEKA
HHHHHHHHCCCCCCCEEEEEECCCCEEEHHHHHHHHHCCCCEECCHHHCCCCCHHHHHHH
KRLYEHLNKGGSIYDFQSDIVLRRVIALFIISIAITILFFINDSVTTPLIVISLLICIGA
HHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IFNQELFTFPSYAKKVKILFDSPSRHIFSGGGFIGIVDYQTKLNNARIRTILGRSSDSGH
HHCCHHHCCCCHHCEEEEEEECCCCCEECCCCEEEEEEEHHHCCCCEEEEEECCCCCCHH
ALLSVVSELKNSASDIINGVEEENKNLKQSVTAITEMTTNLQEVSINVNQVYESVRVAIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHC
ESEKSSIYLGSSMDKVNNLSINIDKLAGNAINLIEDINKISIIMTDIQSIAEQTNLLALN
CCCCCEEEECCCCCCCCCCEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEH
AAIEAARAGEQGRGFAVVADEVRTLANRTQKASLIIQNSVTDLKKILTIWSDEMFISKKE
HHHHHHHCCCCCCCEEEEHHHHHHHHCCHHHHHEEEECCHHHHHHHHHHHCCCCEEECCC
ANDCSDRSSKVNQAMNNILNQINKIGDQASQIALTIEDQENISKEISQGIHQVKGLSQKN
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCCCC
ATQGNKILDYANKVDSATMKILDISKIFK
CCCCCHHHHHHHHHCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDNNEIIFKSTEQLVSITDLEGRITYANEAFCLISGYKVDELKGQNHNIIRHPFMPKLAF
CCCCCEEEECHHHHEEEECCCCEEEECCCEEEEEECCEEHHCCCCCCCEEECCCCCHHHH
EDLWSKLKEGKAWRGIVINRCKNGDYYWVDAYITSILKDNNVIGYQSVRTVPTQKQKEKA
HHHHHHHHCCCCCCCEEEEEECCCCEEEHHHHHHHHHCCCCEECCHHHCCCCCHHHHHHH
KRLYEHLNKGGSIYDFQSDIVLRRVIALFIISIAITILFFINDSVTTPLIVISLLICIGA
HHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
IFNQELFTFPSYAKKVKILFDSPSRHIFSGGGFIGIVDYQTKLNNARIRTILGRSSDSGH
HHCCHHHCCCCHHCEEEEEEECCCCCEECCCCEEEEEEEHHHCCCCEEEEEECCCCCCHH
ALLSVVSELKNSASDIINGVEEENKNLKQSVTAITEMTTNLQEVSINVNQVYESVRVAIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHC
ESEKSSIYLGSSMDKVNNLSINIDKLAGNAINLIEDINKISIIMTDIQSIAEQTNLLALN
CCCCCEEEECCCCCCCCCCEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEH
AAIEAARAGEQGRGFAVVADEVRTLANRTQKASLIIQNSVTDLKKILTIWSDEMFISKKE
HHHHHHHCCCCCCCEEEEHHHHHHHHCCHHHHHEEEECCHHHHHHHHHHHCCCCEEECCC
ANDCSDRSSKVNQAMNNILNQINKIGDQASQIALTIEDQENISKEISQGIHQVKGLSQKN
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCCCC
ATQGNKILDYANKVDSATMKILDISKIFK
CCCCCHHHHHHHHHCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]