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The map label for this gene is hlyB [H]

Identifier: 59714252

GI number: 59714252

Start: 1205151

End: 1206746

Strand: Reverse

Name: hlyB [H]

Synonym: VF_A1069

Alternate gene names: 59714252

Gene position: 1206746-1205151 (Counterclockwise)

Preceding gene: 59714253

Following gene: 59714251

Centisome position: 90.71

GC content: 29.26

Gene sequence:

>1596_bases
ATGAGAAAAATTAGTTTAAAATTACTTTTATTATCCCCTATATTGTTATTTTTAATTACTACGATTGGTTTGTTTATTTA
TATTGTATCGGAAACAGATAATTTAATATATTCTTCCAATCAAGATAGTAAAAATATATTAATACAAGACGCAAAGCTTT
TTGATATTAATGATAACTTAGCAGAAGCTCGTAGACTATTAACAAGGTATATATATACAAGAGATAATGAGTTTAAGAAG
CCGATAAATTTATTGTTGGAATCCTTAAATAAACTGACTGAACAAAGCTCAAATTATAGGGAAATATATAAGGATTTAAA
TAACGAAATACTGAAATATAATGTATTTGCAAAGGATATGTTAAATGATAAAGACAAAGAATTAGACGAATTGCAATATA
AAAAATTTCATGATGATTTTACACACACAGGGAACAATATAGATAAAATTATTGTAAATCTTAAGAAATCAATAAATGAA
TCATCTAGAATAGCTGTTTTATCATTTGAAAAAGAAAGTAATAAAACAAAAAAAACTGTAATTACATTAATTGTAATCAG
TATTTTAATATCTTTGGCAATTAGTCTAAAAATAATACTTAATATAATTAAGGTATTTTCTAACATAAATTATGTTATGG
ATGATGTATCAAAAGGAAATTTAGAACATCATTTAGATGATAAAGGTGATAATGAAATCTATCAACTTAACAAAGCGATC
AATCAAACTTTATTTAAGCTTAAAACAACAATTGCACAATTAAACTCAGTTGGATTAGAGGTCGCAACTGCCGCAACAGA
ACTTTCACAAATTACAGCAAACTCTCAAGAGAGCGCTGAAAGACAATTAAATGAAATTACGTTAGTAGCAACGGCTGTCA
ATGAATTATCTGCTACAGCAGGTGAAGTGAGAGATAATGCTGCTAGTGCTGAAACCAAAGCACAAGAAATTAATACAATT
ACTGAAGAAGCACTTACTATCTTTGATCAAAGTTCTGTAGCGTTTAATGAGGTGATACACTCATTAGATTCACTATCTAA
AACTGTAGTTAATGTAAGCGATAAATCTGAAGAAATAAGAACTATTGTTGATACTATCGGTTCGATTTCTGAGCAAACTA
ATTTGCTTGCATTAAATGCAGCTATTGAAGCAGCCAGAGCCGGCGAGTCTGGACGTGGATTTGCTGTTGTTGCTGATGAG
GTTCGTATTCTTGCGAAACGTACATCTGATTCAACTTATGGTATTCAAACTATTATCGAAGATCTTCGTAGCCAGGCAGA
AATTGCAAATAAAGGGATGAACCAAAGTCTAGAGTTAGTTGATTCAGTTCAGTCTATAAATAAACAAGTTGATAACTCTT
TGAAAAAAGTTCAAGAAGCTTGTACTGAAATCTCAGATATTAATTCATTAGTTGCTACTGCTTCAGAAGAACAATCTCAG
GTATCTAATGAGATAAATAGTAATTTGACTAATATTTCTGACAATGTAGCTTTAGAAACTACAGCAATATCTCAAAGTTC
ATCCGCTAGTCTAGAATTATCAAATTTAGCGGAGAAACAAAAAGAAAGCTTAGATTTCTTTAAAATTGATAAATAA

Upstream 100 bases:

>100_bases
TGAAGATAAATCAATTTCTTTATTTGTTCAATGTTGGTTGAAATATTATGATAAATTATAAAATACTGTCTATAATCATT
AAATTATTTTAGAGTTTGCT

Downstream 100 bases:

>100_bases
AAAGTGGATATGCTACATATAGTATGAATAGTTGAATGAGATACGCTTAATTTTTACTATTATCGAGAAAATCAAGGTGT
CGATTTATATTAATTTGTAG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MRKISLKLLLLSPILLFLITTIGLFIYIVSETDNLIYSSNQDSKNILIQDAKLFDINDNLAEARRLLTRYIYTRDNEFKK
PINLLLESLNKLTEQSSNYREIYKDLNNEILKYNVFAKDMLNDKDKELDELQYKKFHDDFTHTGNNIDKIIVNLKKSINE
SSRIAVLSFEKESNKTKKTVITLIVISILISLAISLKIILNIIKVFSNINYVMDDVSKGNLEHHLDDKGDNEIYQLNKAI
NQTLFKLKTTIAQLNSVGLEVATAATELSQITANSQESAERQLNEITLVATAVNELSATAGEVRDNAASAETKAQEINTI
TEEALTIFDQSSVAFNEVIHSLDSLSKTVVNVSDKSEEIRTIVDTIGSISEQTNLLALNAAIEAARAGESGRGFAVVADE
VRILAKRTSDSTYGIQTIIEDLRSQAEIANKGMNQSLELVDSVQSINKQVDNSLKKVQEACTEISDINSLVATASEEQSQ
VSNEINSNLTNISDNVALETTAISQSSSASLELSNLAEKQKESLDFFKIDK

Sequences:

>Translated_531_residues
MRKISLKLLLLSPILLFLITTIGLFIYIVSETDNLIYSSNQDSKNILIQDAKLFDINDNLAEARRLLTRYIYTRDNEFKK
PINLLLESLNKLTEQSSNYREIYKDLNNEILKYNVFAKDMLNDKDKELDELQYKKFHDDFTHTGNNIDKIIVNLKKSINE
SSRIAVLSFEKESNKTKKTVITLIVISILISLAISLKIILNIIKVFSNINYVMDDVSKGNLEHHLDDKGDNEIYQLNKAI
NQTLFKLKTTIAQLNSVGLEVATAATELSQITANSQESAERQLNEITLVATAVNELSATAGEVRDNAASAETKAQEINTI
TEEALTIFDQSSVAFNEVIHSLDSLSKTVVNVSDKSEEIRTIVDTIGSISEQTNLLALNAAIEAARAGESGRGFAVVADE
VRILAKRTSDSTYGIQTIIEDLRSQAEIANKGMNQSLELVDSVQSINKQVDNSLKKVQEACTEISDINSLVATASEEQSQ
VSNEINSNLTNISDNVALETTAISQSSSASLELSNLAEKQKESLDFFKIDK
>Mature_531_residues
MRKISLKLLLLSPILLFLITTIGLFIYIVSETDNLIYSSNQDSKNILIQDAKLFDINDNLAEARRLLTRYIYTRDNEFKK
PINLLLESLNKLTEQSSNYREIYKDLNNEILKYNVFAKDMLNDKDKELDELQYKKFHDDFTHTGNNIDKIIVNLKKSINE
SSRIAVLSFEKESNKTKKTVITLIVISILISLAISLKIILNIIKVFSNINYVMDDVSKGNLEHHLDDKGDNEIYQLNKAI
NQTLFKLKTTIAQLNSVGLEVATAATELSQITANSQESAERQLNEITLVATAVNELSATAGEVRDNAASAETKAQEINTI
TEEALTIFDQSSVAFNEVIHSLDSLSKTVVNVSDKSEEIRTIVDTIGSISEQTNLLALNAAIEAARAGESGRGFAVVADE
VRILAKRTSDSTYGIQTIIEDLRSQAEIANKGMNQSLELVDSVQSINKQVDNSLKKVQEACTEISDINSLVATASEEQSQ
VSNEINSNLTNISDNVALETTAISQSSSASLELSNLAEKQKESLDFFKIDK

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=353, Percent_Identity=26.9121813031161, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI2367378, Length=319, Percent_Identity=26.0188087774295, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788195, Length=512, Percent_Identity=24.609375, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1788194, Length=359, Percent_Identity=26.7409470752089, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1789453, Length=300, Percent_Identity=27, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59002; Mature: 59002

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKISLKLLLLSPILLFLITTIGLFIYIVSETDNLIYSSNQDSKNILIQDAKLFDINDNL
CCCCHHHHHHHHHHHHHHHHHHHHHEEHEECCCCEEEECCCCCCCEEEECCEEEECCCCH
AEARRLLTRYIYTRDNEFKKPINLLLESLNKLTEQSSNYREIYKDLNNEILKYNVFAKDM
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHEEHHHHHHHH
LNDKDKELDELQYKKFHDDFTHTGNNIDKIIVNLKKSINESSRIAVLSFEKESNKTKKTV
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHH
ITLIVISILISLAISLKIILNIIKVFSNINYVMDDVSKGNLEHHLDDKGDNEIYQLNKAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHCCCCCCCHHHHHHHHHH
NQTLFKLKTTIAQLNSVGLEVATAATELSQITANSQESAERQLNEITLVATAVNELSATA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GEVRDNAASAETKAQEINTITEEALTIFDQSSVAFNEVIHSLDSLSKTVVNVSDKSEEIR
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
TIVDTIGSISEQTNLLALNAAIEAARAGESGRGFAVVADEVRILAKRTSDSTYGIQTIIE
HHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHH
DLRSQAEIANKGMNQSLELVDSVQSINKQVDNSLKKVQEACTEISDINSLVATASEEQSQ
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VSNEINSNLTNISDNVALETTAISQSSSASLELSNLAEKQKESLDFFKIDK
HHHHHHCCCCCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHCCCCEECCC
>Mature Secondary Structure
MRKISLKLLLLSPILLFLITTIGLFIYIVSETDNLIYSSNQDSKNILIQDAKLFDINDNL
CCCCHHHHHHHHHHHHHHHHHHHHHEEHEECCCCEEEECCCCCCCEEEECCEEEECCCCH
AEARRLLTRYIYTRDNEFKKPINLLLESLNKLTEQSSNYREIYKDLNNEILKYNVFAKDM
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHEEHHHHHHHH
LNDKDKELDELQYKKFHDDFTHTGNNIDKIIVNLKKSINESSRIAVLSFEKESNKTKKTV
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHH
ITLIVISILISLAISLKIILNIIKVFSNINYVMDDVSKGNLEHHLDDKGDNEIYQLNKAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHCCCCCCCHHHHHHHHHH
NQTLFKLKTTIAQLNSVGLEVATAATELSQITANSQESAERQLNEITLVATAVNELSATA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GEVRDNAASAETKAQEINTITEEALTIFDQSSVAFNEVIHSLDSLSKTVVNVSDKSEEIR
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
TIVDTIGSISEQTNLLALNAAIEAARAGESGRGFAVVADEVRILAKRTSDSTYGIQTIIE
HHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHH
DLRSQAEIANKGMNQSLELVDSVQSINKQVDNSLKKVQEACTEISDINSLVATASEEQSQ
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
VSNEINSNLTNISDNVALETTAISQSSSASLELSNLAEKQKESLDFFKIDK
HHHHHHCCCCCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]