Click here to switch to the map view.

The map label for this gene is yajL [H]

Identifier: 59714169

GI number: 59714169

Start: 1106235

End: 1106816

Strand: Reverse

Name: yajL [H]

Synonym: VF_A0986

Alternate gene names: 59714169

Gene position: 1106816-1106235 (Counterclockwise)

Preceding gene: 59714170

Following gene: 59714166

Centisome position: 83.2

GC content: 37.11

Gene sequence:

>582_bases
ATGGAAAATAATCAAGTGACAAAGCACGTTGCGGTATTGCTTGCAGATGGTTTTGAAGAGGGAGAAGCGGTTGTTTTTAT
CGATATAATGCGTCGCTTAGACATTAAGGTTGATGTTTTATCTTGCATGGAAACAACGGCGTTAGAAACCTATTTTGAAA
CAAGAATATCTGCAGATTATACGCTAAAAGACAAAAAAGATGTTCTCTATGACGCAGTCATGATGCCTGGAGGGCCTAAA
GGAACAGATAACTTATCTGCAAATTCGATGGTGATCGATTTTCTAAAGTGCCACATAGAGAAAGATAAATACATATGTGC
GTTATGTTCATCTGGAGCTAAGGTATTAGCCGCTAATCACCTTCTTAATGGACGAAACTATACAACTGGTGGTGGACTGG
AAAAGAAATTTACTGATGGTTGTTTCCAAGATAAGAAAGTGGTTGTTGATGGAAAATTCATCAGTGGTAAAGGTCTTGGA
GTGAGCTTTGAATTTGCCTTTACCGTAGCCAAATATCTTTTGTTTGATAATGTTGAAAAAGTAGAGTGGCAAGCACAGCA
TATTTATTTTGATCATTTCTAA

Upstream 100 bases:

>100_bases
GGAACATGGATAGCTCCAACTGAAGCGATTCGGAATCATGATTGGGACATTATTGCTAAAAATGTACGTGAAACTTGTTC
TTTAGTGGTGGGTAATGACG

Downstream 100 bases:

>100_bases
TTGAAAATAGGTTAATAAAAAGGCACTTTATTGAGTGCCTTTTTATTCATAATACAACTTTTTTTGTTTGGATTTATTCA
TTGATAGAAAGCAATAAAAA

Product: 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MENNQVTKHVAVLLADGFEEGEAVVFIDIMRRLDIKVDVLSCMETTALETYFETRISADYTLKDKKDVLYDAVMMPGGPK
GTDNLSANSMVIDFLKCHIEKDKYICALCSSGAKVLAANHLLNGRNYTTGGGLEKKFTDGCFQDKKVVVDGKFISGKGLG
VSFEFAFTVAKYLLFDNVEKVEWQAQHIYFDHF

Sequences:

>Translated_193_residues
MENNQVTKHVAVLLADGFEEGEAVVFIDIMRRLDIKVDVLSCMETTALETYFETRISADYTLKDKKDVLYDAVMMPGGPK
GTDNLSANSMVIDFLKCHIEKDKYICALCSSGAKVLAANHLLNGRNYTTGGGLEKKFTDGCFQDKKVVVDGKFISGKGLG
VSFEFAFTVAKYLLFDNVEKVEWQAQHIYFDHF
>Mature_193_residues
MENNQVTKHVAVLLADGFEEGEAVVFIDIMRRLDIKVDVLSCMETTALETYFETRISADYTLKDKKDVLYDAVMMPGGPK
GTDNLSANSMVIDFLKCHIEKDKYICALCSSGAKVLAANHLLNGRNYTTGGGLEKKFTDGCFQDKKVVVDGKFISGKGLG
VSFEFAFTVAKYLLFDNVEKVEWQAQHIYFDHF

Specific function: Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Interacts with ribosomal subunits, ribosomes and polysomes. Confers resistance to oxidative stress [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=171, Percent_Identity=33.9181286549708, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI31543380, Length=171, Percent_Identity=33.9181286549708, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI87081736, Length=167, Percent_Identity=28.7425149700599, Blast_Score=69, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17531319, Length=164, Percent_Identity=28.6585365853659, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17558714, Length=167, Percent_Identity=29.940119760479, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28571932, Length=187, Percent_Identity=29.4117647058824, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24653499, Length=183, Percent_Identity=29.5081967213115, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006287
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 21577; Mature: 21577

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNQVTKHVAVLLADGFEEGEAVVFIDIMRRLDIKVDVLSCMETTALETYFETRISADY
CCCCHHHHHHHEEEECCCCCCCEEEEEEHHHHCCCEEHHHHHHHHHHHHHHHHHHCCCCE
TLKDKKDVLYDAVMMPGGPKGTDNLSANSMVIDFLKCHIEKDKYICALCSSGAKVLAANH
EECCCHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEEEHH
LLNGRNYTTGGGLEKKFTDGCFQDKKVVVDGKFISGKGLGVSFEFAFTVAKYLLFDNVEK
EECCCCCCCCCCCCCHHCCCCCCCCEEEEECEEECCCCCCEEEHHHHHHHHHHHHCCCHH
VEWQAQHIYFDHF
HEEEEEEEEEECC
>Mature Secondary Structure
MENNQVTKHVAVLLADGFEEGEAVVFIDIMRRLDIKVDVLSCMETTALETYFETRISADY
CCCCHHHHHHHEEEECCCCCCCEEEEEEHHHHCCCEEHHHHHHHHHHHHHHHHHHCCCCE
TLKDKKDVLYDAVMMPGGPKGTDNLSANSMVIDFLKCHIEKDKYICALCSSGAKVLAANH
EECCCHHHHHHHEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEEEHH
LLNGRNYTTGGGLEKKFTDGCFQDKKVVVDGKFISGKGLGVSFEFAFTVAKYLLFDNVEK
EECCCCCCCCCCCCCHHCCCCCCCCEEEEECEEECCCCCCEEEHHHHHHHHHHHHCCCHH
VEWQAQHIYFDHF
HEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9592144 [H]