Click here to switch to the map view.

The map label for this gene is fruK [H]

Identifier: 59714124

GI number: 59714124

Start: 1062481

End: 1063461

Strand: Reverse

Name: fruK [H]

Synonym: VF_A0941

Alternate gene names: 59714124

Gene position: 1063461-1062481 (Counterclockwise)

Preceding gene: 59714125

Following gene: 59714123

Centisome position: 79.94

GC content: 41.49

Gene sequence:

>981_bases
ATGAGTACTCATTTAAAAAGCAAAGTCGTAACTATCACCCTGAACCCTGCTTTAGATTTAACCGGTAGTTTAGATGCGTT
ATCAGTTGGTTCTGTGAGTTTAATAAGTAAAGGCTCACTTCATGCCGCAGGTAAAGGCGTTAATGTGGCAAAAGTGTTGT
CTGACTTAGGTGCAGAGGTAACGGTTACAGGGTTTTTAGGCCGTGATAATGAAGAGCTTTTCTGTCAATTATTTGAAGAG
ATGAAGGCTAAAGATGAATTTATTCGTGTTGATGGTGCAACTCGCATCAATGTGAAGTTAGTTGAATCAGATGGGCGAGT
AAGTGACATTAACTTCCCGGGTGTTGAGGTATCACAACAGGCGATTGCTGAGTTTGAAGTTCGCCTATTTGAATTAGCAA
AAGATCATGACTTCTTTGTTTTAGCGGGTAGCTTACCAAAAGGTATTTCTCCAGAGCAGTGCGCAGAGTGGATTGAAAAA
CTGCATCAAATGGGCAAGAAAGTGTTATTTGATAGTAGTCGTGCTGCACTAGCTGCAGGTTTAGATGCTCACCCTTGGTT
AATTAAACCAAATGATGAAGAGCTGTCGGAATTTGTAGGCCGTGAATTAAATACACCAGAATCATGTCAACAAGCGGCTG
AAGATCTTGCTGAAAAAGGCATTGAAAATATCGTCGTATCTTTAGGTTCAAAAGGGGTGATGTGGCTTGGTCAAAATAAT
CAAGAGCAAGCTGAATGGATGTATTCTCAACCACCTAAAATGAACGTAGTCAGCACGGTTGGTGCAGGTGATACGTTAGT
TGCTGGTCTTTGCTGGGGCCACATGCAGCAAGATTGGGATCGTTCACAAATCTTATCTTTTGCTACCGCTCTTTCTGCTT
TAGCTGTATCGCAGGTCGGCGTTGGTGTTCCAGATATTAAAAACGTACAAGAATTACAACAACAAGTAACCCTACACAAC
CCTATTTCTAGCAACGTGTAA

Upstream 100 bases:

>100_bases
CGGCCATGAACTGCAATTTACCGCAGATGGTGCTGATGCAAAAGAAGCGCTTGCTGGTATTGGTGCTGCGATTGCTTCTG
GTTTAGGCGAGGGTTAATTG

Downstream 100 bases:

>100_bases
TAAAGCTTAGTGATAGATTAAGGACAGAATATGAAAAACATAGCTATCGTAACAGCATGCCCAAGTGGTGTAGCAAACAG
CATTATTGCAGCGGGTTTAT

Product: fructose-1-phosphate kinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSTHLKSKVVTITLNPALDLTGSLDALSVGSVSLISKGSLHAAGKGVNVAKVLSDLGAEVTVTGFLGRDNEELFCQLFEE
MKAKDEFIRVDGATRINVKLVESDGRVSDINFPGVEVSQQAIAEFEVRLFELAKDHDFFVLAGSLPKGISPEQCAEWIEK
LHQMGKKVLFDSSRAALAAGLDAHPWLIKPNDEELSEFVGRELNTPESCQQAAEDLAEKGIENIVVSLGSKGVMWLGQNN
QEQAEWMYSQPPKMNVVSTVGAGDTLVAGLCWGHMQQDWDRSQILSFATALSALAVSQVGVGVPDIKNVQELQQQVTLHN
PISSNV

Sequences:

>Translated_326_residues
MSTHLKSKVVTITLNPALDLTGSLDALSVGSVSLISKGSLHAAGKGVNVAKVLSDLGAEVTVTGFLGRDNEELFCQLFEE
MKAKDEFIRVDGATRINVKLVESDGRVSDINFPGVEVSQQAIAEFEVRLFELAKDHDFFVLAGSLPKGISPEQCAEWIEK
LHQMGKKVLFDSSRAALAAGLDAHPWLIKPNDEELSEFVGRELNTPESCQQAAEDLAEKGIENIVVSLGSKGVMWLGQNN
QEQAEWMYSQPPKMNVVSTVGAGDTLVAGLCWGHMQQDWDRSQILSFATALSALAVSQVGVGVPDIKNVQELQQQVTLHN
PISSNV
>Mature_325_residues
STHLKSKVVTITLNPALDLTGSLDALSVGSVSLISKGSLHAAGKGVNVAKVLSDLGAEVTVTGFLGRDNEELFCQLFEEM
KAKDEFIRVDGATRINVKLVESDGRVSDINFPGVEVSQQAIAEFEVRLFELAKDHDFFVLAGSLPKGISPEQCAEWIEKL
HQMGKKVLFDSSRAALAAGLDAHPWLIKPNDEELSEFVGRELNTPESCQQAAEDLAEKGIENIVVSLGSKGVMWLGQNNQ
EQAEWMYSQPPKMNVVSTVGAGDTLVAGLCWGHMQQDWDRSQILSFATALSALAVSQVGVGVPDIKNVQELQQQVTLHNP
ISSNV

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=315, Percent_Identity=45.0793650793651, Blast_Score=250, Evalue=8e-68,
Organism=Escherichia coli, GI1788017, Length=291, Percent_Identity=26.8041237113402, Blast_Score=104, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 35253; Mature: 35122

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTHLKSKVVTITLNPALDLTGSLDALSVGSVSLISKGSLHAAGKGVNVAKVLSDLGAEV
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHCCCCE
TVTGFLGRDNEELFCQLFEEMKAKDEFIRVDGATRINVKLVESDGRVSDINFPGVEVSQQ
EEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCEEEEEEEEECCCCEEECCCCCCHHHHH
AIAEFEVRLFELAKDHDFFVLAGSLPKGISPEQCAEWIEKLHQMGKKVLFDSSRAALAAG
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCC
LDAHPWLIKPNDEELSEFVGRELNTPESCQQAAEDLAEKGIENIVVSLGSKGVMWLGQNN
CCCCCEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
QEQAEWMYSQPPKMNVVSTVGAGDTLVAGLCWGHMQQDWDRSQILSFATALSALAVSQVG
CHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
VGVPDIKNVQELQQQVTLHNPISSNV
CCCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
STHLKSKVVTITLNPALDLTGSLDALSVGSVSLISKGSLHAAGKGVNVAKVLSDLGAEV
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHCCCCE
TVTGFLGRDNEELFCQLFEEMKAKDEFIRVDGATRINVKLVESDGRVSDINFPGVEVSQQ
EEEEECCCCCHHHHHHHHHHHHCCCCEEEECCCEEEEEEEEECCCCEEECCCCCCHHHHH
AIAEFEVRLFELAKDHDFFVLAGSLPKGISPEQCAEWIEKLHQMGKKVLFDSSRAALAAG
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCC
LDAHPWLIKPNDEELSEFVGRELNTPESCQQAAEDLAEKGIENIVVSLGSKGVMWLGQNN
CCCCCEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
QEQAEWMYSQPPKMNVVSTVGAGDTLVAGLCWGHMQQDWDRSQILSFATALSALAVSQVG
CHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
VGVPDIKNVQELQQQVTLHNPISSNV
CCCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]