Click here to switch to the map view.

The map label for this gene is luxE [H]

Identifier: 59714102

GI number: 59714102

Start: 1043077

End: 1044207

Strand: Reverse

Name: luxE [H]

Synonym: VF_A0919

Alternate gene names: 59714102

Gene position: 1044207-1043077 (Counterclockwise)

Preceding gene: 59714103

Following gene: 59714101

Centisome position: 78.49

GC content: 34.57

Gene sequence:

>1131_bases
ATGACTAATCATATTGAATATAAAAAAAATCAAATCATTGCGAGTTCTGAAATAGATGATCTTATATTTATGAGTGCTCC
ACAAGAGTGGTCACTTGAAGAGCAAAAAGAAATACAAGATAAGCTGGTTAGAGAGGCTTTTCATTTTCATTACAACAGGA
ATGAAAAGTATCGGAATTATTGTATAAGTCAGCATATAAACGAGAATTTGCATTCAATTGATGAAATACCAGTTTTTCCA
ACATCAATATTCAAACATATGAAGTTTCATACTGTAAGTATGGGGGATATTGAGAATTGGCATACAAGTAGTGGAACGCA
GGGGATTAAAAGTTGTATTGCTCGTGATCGTCTTAGCATTGAGCGGTTGCTTGGTTCGGTTAATTTTGGAATGAAGTATG
TCGGAAATTGGTTTGAACATCAGATGGAGTTAGTGAATCTAGGTCCTGATCGATTTAGCGCAAGTAATGTGTGGTTTAAA
TATGTAATGAGTTTAGTTGAGCTACTTTATCCTACAGTATTTACCGTTAACAACGATAAGATTGATTTCGAAGAAACAGT
AAACCATTTATATAGGATTAATAATAGTAATAAAGATATTTGCTTAATTGGTCCTCCATTTTTTGTCAGTCTCTTATGCC
AATATATGAAAGAAAACAATATTGAATTTAAAGGAGAAAATAGATTACATGTTATTACTGGTGGAGGGTGGAAGTCTAAT
GAGAACAGCTCTTTGAATCGTCAAGACTTTAATCAGTTAATTATGGATACTTTCCAATTAGATAATGTTAATCAGATTAG
AGATACATTTAATCAGGTAGAACTTAATACTTGTTTTTTTGAGGATGAATTTCAAAGAAAACATGTTCCACCGTGGGTGT
ATGCTCGGGCTCTTGATCCTGAAACCTTGAAACCCGTAGCCGACGGTGAGCTCGGGTTGTTAAGTTATATGGACGCCTCA
TCGACTGCTTACCCTGCTTTTATTGTTACTGATGATATCGGTATTGTTAGAGAAATAAGAGAACCAGATCCTTACCCTGG
GGTAACAGTTGAAATTGTTCGACGTTTAAATACACGTGCGCAAAAGGGATGTGCTCTTTCTATGGCAAGTTTTATTCAAA
GTACTATTTAG

Upstream 100 bases:

>100_bases
AATCGAAAAGAATCTGCCTTAATAGATTGAGGATAATATTTTAGGTTAAATTGCCATTATTTATCGAGTGTTGTTGACGT
TAGCTATTATTAGGATAGAT

Downstream 100 bases:

>100_bases
GGGAGATTTATGAGTATTGATGGGAAAGTTAAGAAAGTGATATTAGCATCAATCAGAAACAATATATACAAAGTGTTTAT
TACACCAAATAATCCGATTG

Product: long-chain-fatty-acid ligase LuxE

Products: NA

Alternate protein names: Acyl-protein synthetase [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MTNHIEYKKNQIIASSEIDDLIFMSAPQEWSLEEQKEIQDKLVREAFHFHYNRNEKYRNYCISQHINENLHSIDEIPVFP
TSIFKHMKFHTVSMGDIENWHTSSGTQGIKSCIARDRLSIERLLGSVNFGMKYVGNWFEHQMELVNLGPDRFSASNVWFK
YVMSLVELLYPTVFTVNNDKIDFEETVNHLYRINNSNKDICLIGPPFFVSLLCQYMKENNIEFKGENRLHVITGGGWKSN
ENSSLNRQDFNQLIMDTFQLDNVNQIRDTFNQVELNTCFFEDEFQRKHVPPWVYARALDPETLKPVADGELGLLSYMDAS
STAYPAFIVTDDIGIVREIREPDPYPGVTVEIVRRLNTRAQKGCALSMASFIQSTI

Sequences:

>Translated_376_residues
MTNHIEYKKNQIIASSEIDDLIFMSAPQEWSLEEQKEIQDKLVREAFHFHYNRNEKYRNYCISQHINENLHSIDEIPVFP
TSIFKHMKFHTVSMGDIENWHTSSGTQGIKSCIARDRLSIERLLGSVNFGMKYVGNWFEHQMELVNLGPDRFSASNVWFK
YVMSLVELLYPTVFTVNNDKIDFEETVNHLYRINNSNKDICLIGPPFFVSLLCQYMKENNIEFKGENRLHVITGGGWKSN
ENSSLNRQDFNQLIMDTFQLDNVNQIRDTFNQVELNTCFFEDEFQRKHVPPWVYARALDPETLKPVADGELGLLSYMDAS
STAYPAFIVTDDIGIVREIREPDPYPGVTVEIVRRLNTRAQKGCALSMASFIQSTI
>Mature_375_residues
TNHIEYKKNQIIASSEIDDLIFMSAPQEWSLEEQKEIQDKLVREAFHFHYNRNEKYRNYCISQHINENLHSIDEIPVFPT
SIFKHMKFHTVSMGDIENWHTSSGTQGIKSCIARDRLSIERLLGSVNFGMKYVGNWFEHQMELVNLGPDRFSASNVWFKY
VMSLVELLYPTVFTVNNDKIDFEETVNHLYRINNSNKDICLIGPPFFVSLLCQYMKENNIEFKGENRLHVITGGGWKSNE
NSSLNRQDFNQLIMDTFQLDNVNQIRDTFNQVELNTCFFEDEFQRKHVPPWVYARALDPETLKPVADGELGLLSYMDASS
TAYPAFIVTDDIGIVREIREPDPYPGVTVEIVRRLNTRAQKGCALSMASFIQSTI

Specific function: Acyl-protein synthetase activates tetradecanoic acid. It is a component of the fatty acid reductase complex responsible for converting tetradecanoic acid to the aldehyde which serves as substrate in the luciferase-catalyzed reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016671
- InterPro:   IPR007534 [H]

Pfam domain/function: PF04443 LuxE [H]

EC number: =6.2.1.19 [H]

Molecular weight: Translated: 43638; Mature: 43507

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNHIEYKKNQIIASSEIDDLIFMSAPQEWSLEEQKEIQDKLVREAFHFHYNRNEKYRNY
CCCCCCCCCCEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
CISQHINENLHSIDEIPVFPTSIFKHMKFHTVSMGDIENWHTSSGTQGIKSCIARDRLSI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
ERLLGSVNFGMKYVGNWFEHQMELVNLGPDRFSASNVWFKYVMSLVELLYPTVFTVNNDK
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCC
IDFEETVNHLYRINNSNKDICLIGPPFFVSLLCQYMKENNIEFKGENRLHVITGGGWKSN
CCHHHHHHHHHEECCCCCCEEEECCHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCCCC
ENSSLNRQDFNQLIMDTFQLDNVNQIRDTFNQVELNTCFFEDEFQRKHVPPWVYARALDP
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHEEHHHEEECHHHHHCCCCCHHEEECCCH
ETLKPVADGELGLLSYMDASSTAYPAFIVTDDIGIVREIREPDPYPGVTVEIVRRLNTRA
HHCCCCCCCCCHHHEECCCCCCCCCEEEEECCHHHHHHHCCCCCCCCHHHHHHHHHHHHH
QKGCALSMASFIQSTI
HCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TNHIEYKKNQIIASSEIDDLIFMSAPQEWSLEEQKEIQDKLVREAFHFHYNRNEKYRNY
CCCCCCCCCEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
CISQHINENLHSIDEIPVFPTSIFKHMKFHTVSMGDIENWHTSSGTQGIKSCIARDRLSI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHH
ERLLGSVNFGMKYVGNWFEHQMELVNLGPDRFSASNVWFKYVMSLVELLYPTVFTVNNDK
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCC
IDFEETVNHLYRINNSNKDICLIGPPFFVSLLCQYMKENNIEFKGENRLHVITGGGWKSN
CCHHHHHHHHHEECCCCCCEEEECCHHHHHHHHHHHHHCCCEEECCCEEEEEECCCCCCC
ENSSLNRQDFNQLIMDTFQLDNVNQIRDTFNQVELNTCFFEDEFQRKHVPPWVYARALDP
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHEEHHHEEECHHHHHCCCCCHHEEECCCH
ETLKPVADGELGLLSYMDASSTAYPAFIVTDDIGIVREIREPDPYPGVTVEIVRRLNTRA
HHCCCCCCCCCHHHEECCCCCCCCCEEEEECCHHHHHHHCCCCCCCCHHHHHHHHHHHHH
QKGCALSMASFIQSTI
HCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1915359 [H]