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The map label for this gene is tcpB [H]

Identifier: 59714057

GI number: 59714057

Start: 985700

End: 987037

Strand: Reverse

Name: tcpB [H]

Synonym: VF_A0874

Alternate gene names: 59714057

Gene position: 987037-985700 (Counterclockwise)

Preceding gene: 59714058

Following gene: 59714056

Centisome position: 74.19

GC content: 34.75

Gene sequence:

>1338_bases
ATGTTAAAACAACAGCGAGGGGCTACTCTATTAGAAGCTGTTCTTGCTGCTGCGATAATTGGCTGGGGGTTGGCTTTTGC
TGGCGCCCAGTTAATTAAATCAGCAAAGAACAAGCAGATAGATAAGAATGCGTCTAAATTGATAAATTTTCAATATGAAG
TTAAACAACTTGCGTCTACTGTTTATTTTAATGTTATCGCTCCTGGTTCTGGTGCTAGTAGTAAAAAAGTTAATCCTTTG
CTGGTTTCTTCATCTACAGGGAAGTTTATGTATGAGAAGGATTTGAGGTGGATGAAACAAACCGACTGTGAGCTTTTAGG
TGGCATTTCTGGTCAAATACCTGTGGGGATAAGTAGACCGTTTGTTGATTGTGATTATAGTCCAGACTTTTTTGGTGTTG
AATATATAGGGACTGAGTTTACATTTGTTCCATATAATTTAATTAAATATCCTTCAGCAAAGCGTTTTATTACTTCAGCT
CAGAGTTATTATGTAAATAAGAGTAATGTGGAAGTAGAAGATATTTTATCTATTATATCAAAGCTGAGCGATCAAAAGAG
AGATGACGGTTTTTCAGTTAGTGATAATGACATAATTATTTCTAAATTTGTTAAACTTGATGATGTTAATTATCGTGAAG
TGCCAGATACAGCGAAAAGTTGGGCTGAATTAATTGATAATATATCCCTTTTAGATTCTTTTATTAAGGAGGTTACATCT
GGTGACAACTATTTGGGTTTTAGAATAAAGAGTTTTTATAATGAAGATATCTATTTAAAACGTGATGGTAGTATCCCCAT
GTCAGGAAAAGCTAAGCTTTGTTGGGATGGCTATTCTGGAAAAGAAGGGCCTTGTTTATCTGCAAGCAGTGAATCTGACG
GAACTAGAAACTATTTGATAGCTGATGGTGGATTTGCGTTTGGTGAGAAAATAAAACGAACACCTATTGAAATATCATAT
AAAACATTTTCTCGAAGCAATAGAAATAACATTGAAATACCATATTTAAATTGTCCGCAAACAGAACCGGTGATGTTAAA
TAAAATGGTTGCGATACCAAGTTCATTTTCATCTGGCTCTGAAGAAAGAAGTGACTTCTCAGACCCAAATAGTATTAAGA
GCTATGGTACAAAAGGCGCTAGTAATAAACATGCATTCATTTCAGGTGTATCAATGGAATGGGCTCCAGTAGATTCAAGA
AAAGTATGGACAATAAAAGGTGGGATAGGTATTGACGGTGCATATGAAAAAGATAACGGAAACTCGTCAATGTTAAATAA
TCCACTATCAATGTCTTTTATAGTTATGCAGTGGTGTGAAGAAAAACCAAAAGGATAA

Upstream 100 bases:

>100_bases
AATCTTGACCACATCTCGGCTCTGTGTGGTGGGCCAGGTGCGGGTGATTCGTACTTTGATGTTTTTGTTGGTAATCGTTA
ATTACTTTTAGGTTGGAACA

Downstream 100 bases:

>100_bases
TAATATGAAAAAAAATATAATTTTAATTACTTTAGCTATTATGTCATCGGGGTGTTCATCGATTGAAAGCCTGAAAACAG
ATAAAGGAAATCCTAGTTAT

Product: toxin coregulated pilus biosynthesis protein TcpB

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpB [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MLKQQRGATLLEAVLAAAIIGWGLAFAGAQLIKSAKNKQIDKNASKLINFQYEVKQLASTVYFNVIAPGSGASSKKVNPL
LVSSSTGKFMYEKDLRWMKQTDCELLGGISGQIPVGISRPFVDCDYSPDFFGVEYIGTEFTFVPYNLIKYPSAKRFITSA
QSYYVNKSNVEVEDILSIISKLSDQKRDDGFSVSDNDIIISKFVKLDDVNYREVPDTAKSWAELIDNISLLDSFIKEVTS
GDNYLGFRIKSFYNEDIYLKRDGSIPMSGKAKLCWDGYSGKEGPCLSASSESDGTRNYLIADGGFAFGEKIKRTPIEISY
KTFSRSNRNNIEIPYLNCPQTEPVMLNKMVAIPSSFSSGSEERSDFSDPNSIKSYGTKGASNKHAFISGVSMEWAPVDSR
KVWTIKGGIGIDGAYEKDNGNSSMLNNPLSMSFIVMQWCEEKPKG

Sequences:

>Translated_445_residues
MLKQQRGATLLEAVLAAAIIGWGLAFAGAQLIKSAKNKQIDKNASKLINFQYEVKQLASTVYFNVIAPGSGASSKKVNPL
LVSSSTGKFMYEKDLRWMKQTDCELLGGISGQIPVGISRPFVDCDYSPDFFGVEYIGTEFTFVPYNLIKYPSAKRFITSA
QSYYVNKSNVEVEDILSIISKLSDQKRDDGFSVSDNDIIISKFVKLDDVNYREVPDTAKSWAELIDNISLLDSFIKEVTS
GDNYLGFRIKSFYNEDIYLKRDGSIPMSGKAKLCWDGYSGKEGPCLSASSESDGTRNYLIADGGFAFGEKIKRTPIEISY
KTFSRSNRNNIEIPYLNCPQTEPVMLNKMVAIPSSFSSGSEERSDFSDPNSIKSYGTKGASNKHAFISGVSMEWAPVDSR
KVWTIKGGIGIDGAYEKDNGNSSMLNNPLSMSFIVMQWCEEKPKG
>Mature_445_residues
MLKQQRGATLLEAVLAAAIIGWGLAFAGAQLIKSAKNKQIDKNASKLINFQYEVKQLASTVYFNVIAPGSGASSKKVNPL
LVSSSTGKFMYEKDLRWMKQTDCELLGGISGQIPVGISRPFVDCDYSPDFFGVEYIGTEFTFVPYNLIKYPSAKRFITSA
QSYYVNKSNVEVEDILSIISKLSDQKRDDGFSVSDNDIIISKFVKLDDVNYREVPDTAKSWAELIDNISLLDSFIKEVTS
GDNYLGFRIKSFYNEDIYLKRDGSIPMSGKAKLCWDGYSGKEGPCLSASSESDGTRNYLIADGGFAFGEKIKRTPIEISY
KTFSRSNRNNIEIPYLNCPQTEPVMLNKMVAIPSSFSSGSEERSDFSDPNSIKSYGTKGASNKHAFISGVSMEWAPVDSR
KVWTIKGGIGIDGAYEKDNGNSSMLNNPLSMSFIVMQWCEEKPKG

Specific function: Involved in TCP pilus biogenesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 49253; Mature: 49253

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKQQRGATLLEAVLAAAIIGWGLAFAGAQLIKSAKNKQIDKNASKLINFQYEVKQLAST
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHEEHHHHHHHHHHH
VYFNVIAPGSGASSKKVNPLLVSSSTGKFMYEKDLRWMKQTDCELLGGISGQIPVGISRP
EEEEEEECCCCCCCCCCCEEEEECCCCCEEEHHHHHHHHHCCHHHHCCCCCCCCCCCCCC
FVDCDYSPDFFGVEYIGTEFTFVPYNLIKYPSAKRFITSAQSYYVNKSNVEVEDILSIIS
EEECCCCCCCCEEEEECCEEEEECHHHHCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHH
KLSDQKRDDGFSVSDNDIIISKFVKLDDVNYREVPDTAKSWAELIDNISLLDSFIKEVTS
HHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GDNYLGFRIKSFYNEDIYLKRDGSIPMSGKAKLCWDGYSGKEGPCLSASSESDGTRNYLI
CCCEEEEEEEEECCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEE
ADGGFAFGEKIKRTPIEISYKTFSRSNRNNIEIPYLNCPQTEPVMLNKMVAIPSSFSSGS
ECCCCHHHHHHCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHEEECCCCCCCCC
EERSDFSDPNSIKSYGTKGASNKHAFISGVSMEWAPVDSRKVWTIKGGIGIDGAYEKDNG
CHHCCCCCCHHHHHHCCCCCCCCEEEEEECEEEEECCCCCEEEEEECCCCCCCCCCCCCC
NSSMLNNPLSMSFIVMQWCEEKPKG
CHHHHCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLKQQRGATLLEAVLAAAIIGWGLAFAGAQLIKSAKNKQIDKNASKLINFQYEVKQLAST
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHEEHHHHHHHHHHH
VYFNVIAPGSGASSKKVNPLLVSSSTGKFMYEKDLRWMKQTDCELLGGISGQIPVGISRP
EEEEEEECCCCCCCCCCCEEEEECCCCCEEEHHHHHHHHHCCHHHHCCCCCCCCCCCCCC
FVDCDYSPDFFGVEYIGTEFTFVPYNLIKYPSAKRFITSAQSYYVNKSNVEVEDILSIIS
EEECCCCCCCCEEEEECCEEEEECHHHHCCCCHHHHHHHHHHHEECCCCCCHHHHHHHHH
KLSDQKRDDGFSVSDNDIIISKFVKLDDVNYREVPDTAKSWAELIDNISLLDSFIKEVTS
HHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
GDNYLGFRIKSFYNEDIYLKRDGSIPMSGKAKLCWDGYSGKEGPCLSASSESDGTRNYLI
CCCEEEEEEEEECCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEEE
ADGGFAFGEKIKRTPIEISYKTFSRSNRNNIEIPYLNCPQTEPVMLNKMVAIPSSFSSGS
ECCCCHHHHHHCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHEEECCCCCCCCC
EERSDFSDPNSIKSYGTKGASNKHAFISGVSMEWAPVDSRKVWTIKGGIGIDGAYEKDNG
CHHCCCCCCHHHHHHCCCCCCCCEEEEEECEEEEECCCCCEEEEEECCCCCCCCCCCCCC
NSSMLNNPLSMSFIVMQWCEEKPKG
CHHHHCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8621096; 10952301; 2576015 [H]