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The map label for this gene is speB [H]

Identifier: 59714022

GI number: 59714022

Start: 946838

End: 947764

Strand: Reverse

Name: speB [H]

Synonym: VF_A0839

Alternate gene names: 59714022

Gene position: 947764-946838 (Counterclockwise)

Preceding gene: 59714023

Following gene: 59714020

Centisome position: 71.24

GC content: 41.32

Gene sequence:

>927_bases
ATGAACGATTTATTCACCAAAAAAGATTATTCATTGTACTCAAATGCAATGACATTTATGCGTCGCCCATTGGTACAAAA
CCCAATTGATAACGACGCAGATATTGTTGTATTAGGTGCACCATTAGATATGGCAACCTCAGGTCGCCCTGGTGCGCGTT
TAGGTCCTGATGCGATCCGTCGTGCATCGGTAAATCTAGCGTGGGAAGGTAAAAAATTCCCATGGGATTTCAATGTATTT
GATCATACAAAAGTGATTGATTCAGGTGACCTTGTTTTTGATACTGGCGATGCGGAAGATTTAACGGTACGCCTTGAAGC
GGCAGCTGATGCGATCCTAAATAGTGGTAAAACACTATTAGGTCTAGGTGGTGATCACTTTATTACTCTGCCTTTGCTAC
GTGCTTATGGTAAAAAATACGGTGAAATGGCATTAATTCATTTTGATGCTCATACTGACACTTATAGTCATGGTAGCCGC
TACGATCACGGTACTATGTTCTATCATGCTCCAAATGAAGGGCTTATTTCACCTGAGCACTCTGTTCAAATTGGTATTCG
TACTGAGTATGACCAAAAAGATCACGGCTTTAATGTGATTAACGCAATGCAAGCCAATGACATGAGTGTTGATGCTATTA
TCGAGCAAGTAAAAGGCATTGTTGGTGACAAACCAGTATACCTAACGTTTGATATTGATTGTCTTGATCCTGCCTTTGCG
CCGGGTACAGGCACACCGGTATGTGGTGGCTTGAACTCAGATAAGATCTTAAAAATCATCCGTGGTTTGCAAGGTATCAA
CATGGTTGGTATGGATGTGGTAGAAGTATCACCTGCGTATGATCAAAGTGATATCACGGCATTGGCTGGTGCAACGATTG
CTTTAGAGCTTTTGTATGTTTGGACTGCGAATCGTTTAAACAAATAA

Upstream 100 bases:

>100_bases
AAGACATGGTAACAGCGAAAGTTGCAGAAGAAGAACAACAAAGCGTGCTTGAAGAGTTAGAGCAAGGCTTAATGGGTTAC
ACCTATTTGGAAGATTTTTA

Downstream 100 bases:

>100_bases
GCGTGATAAGCTGAGTAAAAATAAACCCGTTGAATGAGAGTTCAACGGGTTTATGCTTTTCAGGATTCAGGTTATTTAAA
GCAACGAGATTGTGACACGT

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNDLFTKKDYSLYSNAMTFMRRPLVQNPIDNDADIVVLGAPLDMATSGRPGARLGPDAIRRASVNLAWEGKKFPWDFNVF
DHTKVIDSGDLVFDTGDAEDLTVRLEAAADAILNSGKTLLGLGGDHFITLPLLRAYGKKYGEMALIHFDAHTDTYSHGSR
YDHGTMFYHAPNEGLISPEHSVQIGIRTEYDQKDHGFNVINAMQANDMSVDAIIEQVKGIVGDKPVYLTFDIDCLDPAFA
PGTGTPVCGGLNSDKILKIIRGLQGINMVGMDVVEVSPAYDQSDITALAGATIALELLYVWTANRLNK

Sequences:

>Translated_308_residues
MNDLFTKKDYSLYSNAMTFMRRPLVQNPIDNDADIVVLGAPLDMATSGRPGARLGPDAIRRASVNLAWEGKKFPWDFNVF
DHTKVIDSGDLVFDTGDAEDLTVRLEAAADAILNSGKTLLGLGGDHFITLPLLRAYGKKYGEMALIHFDAHTDTYSHGSR
YDHGTMFYHAPNEGLISPEHSVQIGIRTEYDQKDHGFNVINAMQANDMSVDAIIEQVKGIVGDKPVYLTFDIDCLDPAFA
PGTGTPVCGGLNSDKILKIIRGLQGINMVGMDVVEVSPAYDQSDITALAGATIALELLYVWTANRLNK
>Mature_308_residues
MNDLFTKKDYSLYSNAMTFMRRPLVQNPIDNDADIVVLGAPLDMATSGRPGARLGPDAIRRASVNLAWEGKKFPWDFNVF
DHTKVIDSGDLVFDTGDAEDLTVRLEAAADAILNSGKTLLGLGGDHFITLPLLRAYGKKYGEMALIHFDAHTDTYSHGSR
YDHGTMFYHAPNEGLISPEHSVQIGIRTEYDQKDHGFNVINAMQANDMSVDAIIEQVKGIVGDKPVYLTFDIDCLDPAFA
PGTGTPVCGGLNSDKILKIIRGLQGINMVGMDVVEVSPAYDQSDITALAGATIALELLYVWTANRLNK

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=291, Percent_Identity=42.6116838487972, Blast_Score=202, Evalue=2e-52,
Organism=Homo sapiens, GI10947139, Length=318, Percent_Identity=25.4716981132075, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI4502215, Length=296, Percent_Identity=24.3243243243243, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1789306, Length=305, Percent_Identity=62.6229508196721, Blast_Score=386, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6325146, Length=220, Percent_Identity=28.1818181818182, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 33654; Mature: 33654

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLFTKKDYSLYSNAMTFMRRPLVQNPIDNDADIVVLGAPLDMATSGRPGARLGPDAIR
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHH
RASVNLAWEGKKFPWDFNVFDHTKVIDSGDLVFDTGDAEDLTVRLEAAADAILNSGKTLL
HEEEEEEECCCCCCEECCCCCCEEEECCCCEEEECCCCCCEEEEEHHHHHHHHHCCCEEE
GLGGDHFITLPLLRAYGKKYGEMALIHFDAHTDTYSHGSRYDHGTMFYHAPNEGLISPEH
ECCCCCEEHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
SVQIGIRTEYDQKDHGFNVINAMQANDMSVDAIIEQVKGIVGDKPVYLTFDIDCLDPAFA
CEEEEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCC
PGTGTPVCGGLNSDKILKIIRGLQGINMVGMDVVEVSPAYDQSDITALAGATIALELLYV
CCCCCCEECCCCHHHHHHHHHHCCCCCEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHE
WTANRLNK
EHHHHCCC
>Mature Secondary Structure
MNDLFTKKDYSLYSNAMTFMRRPLVQNPIDNDADIVVLGAPLDMATSGRPGARLGPDAIR
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHH
RASVNLAWEGKKFPWDFNVFDHTKVIDSGDLVFDTGDAEDLTVRLEAAADAILNSGKTLL
HEEEEEEECCCCCCEECCCCCCEEEECCCCEEEECCCCCCEEEEEHHHHHHHHHCCCEEE
GLGGDHFITLPLLRAYGKKYGEMALIHFDAHTDTYSHGSRYDHGTMFYHAPNEGLISPEH
ECCCCCEEHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
SVQIGIRTEYDQKDHGFNVINAMQANDMSVDAIIEQVKGIVGDKPVYLTFDIDCLDPAFA
CEEEEEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCC
PGTGTPVCGGLNSDKILKIIRGLQGINMVGMDVVEVSPAYDQSDITALAGATIALELLYV
CCCCCCEECCCCHHHHHHHHHHCCCCCEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHE
WTANRLNK
EHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA