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The map label for this gene is malP [H]

Identifier: 59713993

GI number: 59713993

Start: 912778

End: 915231

Strand: Reverse

Name: malP [H]

Synonym: VF_A0810

Alternate gene names: 59713993

Gene position: 915231-912778 (Counterclockwise)

Preceding gene: 59713996

Following gene: 172087815

Centisome position: 68.8

GC content: 39.85

Gene sequence:

>2454_bases
ATGAAAACGAATAACATAGAAAAATTTGATAAAGCGGCGTTTAAAGCCTCTGTAAAGCAGCATTTAGTGACAACATTCGC
TGCAGATGAAAAAACAGCGAGCGCTAAAGTATGGTATTTAGCAATGGGTAAAGCTCTAGCTGAATTAACGACATTTGATC
TTGTTGCTACAGAAAATGACGAAAAAATAAAAAACGCACGCAGCGTAAACTATCTATCTTTAGAGTTTTTAATTGGACGT
CTAACGGGCAACAACCTAATTAGTATGGGTCTTTATGAAGAGATCACTGAAGCAATGGGTGAGCTTGGTTATAATTTAAC
GGATTTATTAGAAGAAGAGCGTGATCCTGCTTTAGGTAACGGTGGTCTCGGTCGTTTAGCTGCGTGTTTTATGGATTCAT
TAGCTGCTCAAGAATATCCAGCGATTGGTTACGGTTTGCATTACGAATACGGTTTGTTCCGCCAATCTTTTGAAGACGGA
CGACAAAAAGAAGCGCCTGATGCATGGTGTGGAGTAGAAGGCTATCCTTGGGAAGTGGCTCGTCCTGATTTTGCACAGCA
AGTTGGATTTTATGGTCATGTAGAAACGTACACTGAAAAAGGCCAAGAGAAACGTCGCTGGGTACCAGGTATGTCAGTTG
AAGGTATGCCTTGGGATTTACCTATTGTTGGTTACCAAAGTGATACGGTTTACCCATTACGTTTGTGGGAATGTCGTGCA
AAAGCACCGTTTAGCCTTGCAAGCTTTAATAATGGTGACTACTTTGAAGCGCAACACGCCTTAATTGATGCTGGTAACGT
AACGAAAGTTCTGTATCCAAATGATAACCACGAGAAAGGCAAAACATTACGTTTGATGCAACAGTATTTCCACTGTGCGT
GTTCTATTGCTGATATCTTACGTCGTCATGATGCTGCGGGTCATAAGATTGAAGATCTTTCTAAATATGAAACGATCCAA
TTAAACGATACACACCCAACAATCGGTATTCCTGAGTTAATGCGCGTACTTATTGATGTACGTGGTTTATCGTGGGATAC
GGCATGGGAAATCTGTTCAAACACGTTTGCTTATACTAACCACACATTGTTACCTGAAGCGTTAGAGACATGGAGTGAAT
CACTGATTTCTCGACTTTTACCTCGTCATATGGAAATCATTTATCAGATTAACTACCTATTCTTAGAAGGCGTGAAACTG
AAGTGGCCAGGTGATGTTGATAAATTACGCAAGTTATCAATCATCGAAGAAGGCACACATCGTATGGTGCGCATGGCGAA
TTTATGTGTGGTTTCATCTTATGCCGTGAATGGTGTGGCAGCACTTCACTCTGAGTTAGTTAAGCGTGATTTATTCCCAG
AGTTTAATGAATATTTCCCAGGAAAACTAACGAATGTAACTAACGGTGTTACTCCTCGTCGTTGGCTGAAATTCTGTAAC
CCTGGTCTTTCAAACCTTATTTCTGGAAAAATTGGGAATGAGTGGCCTGCACATCTTGATCAACTGAGTGACATTGCTGT
TTTTGCCGATGATGAGAAATTCCAAAAAGAATTCATGGCTGTGAAAAAACAAAATAAACAGCGTTTAGCTAATTGGGTTC
AAGAAAACATGGGTATTGAATTAAATACTGATGCCATCTTTGATGTTCAAATTAAGCGTTTACATGAATACAAACGTCAG
CATTTGGATTTATTAAATATTCTTTCTTTATACCATCGTATATTGAACGAACCTGGTTTTGATATGCACCCACGTGTGTT
TTTCTTTGCAGCAAAAGCAGCGCCGGGTTACCACTTAGCAAAAGAGATCATCTTTGCCATCAATAAAGTGGCAGAAAAAG
TAAATAACGATCCTCGTGTGTCTGATTTACTGAAAGTTGTATTTATTCCTGATTACCGTGTGAGCATGGCTGAAATTATC
ATTCCAGCAGCGGATGTATCTGAGCAAATTTCAACAGCGGGTAAAGAAGCATCTGGTACAGGTAACATGAAAATGGCACT
AAACGGTGCGCTGACTGTTGGTACGATGGATGGTGCAAACGTTGAGATCCGCGAAGAAGTAGGTGACGAAAATATCTTCA
TCTTTGGTTTAGAGGTTGATGAAGTTGAGGCGTTAAAAGCATCAGGATATAGCCCGTATAAGTACTATGAAGCCGATTCA
TTATTACAAGCATCATTAGATTTATTAGCTGGTGATGAATTTACTCCGGGTAAAGTGGGTCTGTTATCTGCAATTCGTGA
CAACCTATTGTATGGCGGTGACCCATATTTAGTTCTTGCTGATTTTGCTGATTATGTTCGTGCTCAGAACGACATTGATG
CAGCATATCGTGACCAAAAACAGTGGGCGAAAATGGCTATTTTAAACACTGCTTTGGTTGGTAAATTTAGTTCAGACCGC
AGTATCCGTGATTATGTAAATAACATTTGGAAACTGGAATCAGTAAACCGTTAA

Upstream 100 bases:

>100_bases
TCTCACCCTTATCTCATCCCCCAAAAAGGAGGATGTGACTCTTATTCGAACAAGGCAGGATTGATAACAGTTGATTATGA
ACCTTCGTGAGAGATTTAAG

Downstream 100 bases:

>100_bases
TTAATAAAATTATAATATGAGGGCAGTATTGTACTGCCCTTGGAGAAAAGCGATGAAAGATAATAACAATGTACTCCATC
AAGTCGCAGAACTGGCAGGG

Product: maltodextrin phosphorylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 817; Mature: 817

Protein sequence:

>817_residues
MKTNNIEKFDKAAFKASVKQHLVTTFAADEKTASAKVWYLAMGKALAELTTFDLVATENDEKIKNARSVNYLSLEFLIGR
LTGNNLISMGLYEEITEAMGELGYNLTDLLEEERDPALGNGGLGRLAACFMDSLAAQEYPAIGYGLHYEYGLFRQSFEDG
RQKEAPDAWCGVEGYPWEVARPDFAQQVGFYGHVETYTEKGQEKRRWVPGMSVEGMPWDLPIVGYQSDTVYPLRLWECRA
KAPFSLASFNNGDYFEAQHALIDAGNVTKVLYPNDNHEKGKTLRLMQQYFHCACSIADILRRHDAAGHKIEDLSKYETIQ
LNDTHPTIGIPELMRVLIDVRGLSWDTAWEICSNTFAYTNHTLLPEALETWSESLISRLLPRHMEIIYQINYLFLEGVKL
KWPGDVDKLRKLSIIEEGTHRMVRMANLCVVSSYAVNGVAALHSELVKRDLFPEFNEYFPGKLTNVTNGVTPRRWLKFCN
PGLSNLISGKIGNEWPAHLDQLSDIAVFADDEKFQKEFMAVKKQNKQRLANWVQENMGIELNTDAIFDVQIKRLHEYKRQ
HLDLLNILSLYHRILNEPGFDMHPRVFFFAAKAAPGYHLAKEIIFAINKVAEKVNNDPRVSDLLKVVFIPDYRVSMAEII
IPAADVSEQISTAGKEASGTGNMKMALNGALTVGTMDGANVEIREEVGDENIFIFGLEVDEVEALKASGYSPYKYYEADS
LLQASLDLLAGDEFTPGKVGLLSAIRDNLLYGGDPYLVLADFADYVRAQNDIDAAYRDQKQWAKMAILNTALVGKFSSDR
SIRDYVNNIWKLESVNR

Sequences:

>Translated_817_residues
MKTNNIEKFDKAAFKASVKQHLVTTFAADEKTASAKVWYLAMGKALAELTTFDLVATENDEKIKNARSVNYLSLEFLIGR
LTGNNLISMGLYEEITEAMGELGYNLTDLLEEERDPALGNGGLGRLAACFMDSLAAQEYPAIGYGLHYEYGLFRQSFEDG
RQKEAPDAWCGVEGYPWEVARPDFAQQVGFYGHVETYTEKGQEKRRWVPGMSVEGMPWDLPIVGYQSDTVYPLRLWECRA
KAPFSLASFNNGDYFEAQHALIDAGNVTKVLYPNDNHEKGKTLRLMQQYFHCACSIADILRRHDAAGHKIEDLSKYETIQ
LNDTHPTIGIPELMRVLIDVRGLSWDTAWEICSNTFAYTNHTLLPEALETWSESLISRLLPRHMEIIYQINYLFLEGVKL
KWPGDVDKLRKLSIIEEGTHRMVRMANLCVVSSYAVNGVAALHSELVKRDLFPEFNEYFPGKLTNVTNGVTPRRWLKFCN
PGLSNLISGKIGNEWPAHLDQLSDIAVFADDEKFQKEFMAVKKQNKQRLANWVQENMGIELNTDAIFDVQIKRLHEYKRQ
HLDLLNILSLYHRILNEPGFDMHPRVFFFAAKAAPGYHLAKEIIFAINKVAEKVNNDPRVSDLLKVVFIPDYRVSMAEII
IPAADVSEQISTAGKEASGTGNMKMALNGALTVGTMDGANVEIREEVGDENIFIFGLEVDEVEALKASGYSPYKYYEADS
LLQASLDLLAGDEFTPGKVGLLSAIRDNLLYGGDPYLVLADFADYVRAQNDIDAAYRDQKQWAKMAILNTALVGKFSSDR
SIRDYVNNIWKLESVNR
>Mature_817_residues
MKTNNIEKFDKAAFKASVKQHLVTTFAADEKTASAKVWYLAMGKALAELTTFDLVATENDEKIKNARSVNYLSLEFLIGR
LTGNNLISMGLYEEITEAMGELGYNLTDLLEEERDPALGNGGLGRLAACFMDSLAAQEYPAIGYGLHYEYGLFRQSFEDG
RQKEAPDAWCGVEGYPWEVARPDFAQQVGFYGHVETYTEKGQEKRRWVPGMSVEGMPWDLPIVGYQSDTVYPLRLWECRA
KAPFSLASFNNGDYFEAQHALIDAGNVTKVLYPNDNHEKGKTLRLMQQYFHCACSIADILRRHDAAGHKIEDLSKYETIQ
LNDTHPTIGIPELMRVLIDVRGLSWDTAWEICSNTFAYTNHTLLPEALETWSESLISRLLPRHMEIIYQINYLFLEGVKL
KWPGDVDKLRKLSIIEEGTHRMVRMANLCVVSSYAVNGVAALHSELVKRDLFPEFNEYFPGKLTNVTNGVTPRRWLKFCN
PGLSNLISGKIGNEWPAHLDQLSDIAVFADDEKFQKEFMAVKKQNKQRLANWVQENMGIELNTDAIFDVQIKRLHEYKRQ
HLDLLNILSLYHRILNEPGFDMHPRVFFFAAKAAPGYHLAKEIIFAINKVAEKVNNDPRVSDLLKVVFIPDYRVSMAEII
IPAADVSEQISTAGKEASGTGNMKMALNGALTVGTMDGANVEIREEVGDENIFIFGLEVDEVEALKASGYSPYKYYEADS
LLQASLDLLAGDEFTPGKVGLLSAIRDNLLYGGDPYLVLADFADYVRAQNDIDAAYRDQKQWAKMAILNTALVGKFSSDR
SIRDYVNNIWKLESVNR

Specific function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties [

COG id: COG0058

COG function: function code G; Glucan phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycogen phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI71037379, Length=810, Percent_Identity=46.5432098765432, Blast_Score=714, Evalue=0.0,
Organism=Homo sapiens, GI5032009, Length=808, Percent_Identity=45.1732673267327, Blast_Score=713, Evalue=0.0,
Organism=Homo sapiens, GI21361370, Length=812, Percent_Identity=46.1822660098522, Blast_Score=701, Evalue=0.0,
Organism=Homo sapiens, GI255653002, Length=695, Percent_Identity=48.2014388489209, Blast_Score=677, Evalue=0.0,
Organism=Homo sapiens, GI257900462, Length=729, Percent_Identity=44.8559670781893, Blast_Score=642, Evalue=0.0,
Organism=Escherichia coli, GI48994936, Length=779, Percent_Identity=57.7663671373556, Blast_Score=905, Evalue=0.0,
Organism=Escherichia coli, GI2367228, Length=803, Percent_Identity=45.5790784557908, Blast_Score=705, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17564550, Length=810, Percent_Identity=47.7777777777778, Blast_Score=761, Evalue=0.0,
Organism=Caenorhabditis elegans, GI32566204, Length=811, Percent_Identity=47.7188655980271, Blast_Score=759, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325418, Length=852, Percent_Identity=43.6619718309859, Blast_Score=645, Evalue=0.0,
Organism=Drosophila melanogaster, GI78706832, Length=807, Percent_Identity=47.8314745972739, Blast_Score=754, Evalue=0.0,
Organism=Drosophila melanogaster, GI24581010, Length=807, Percent_Identity=47.8314745972739, Blast_Score=754, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011833
- InterPro:   IPR000811 [H]

Pfam domain/function: PF00343 Phosphorylase [H]

EC number: =2.4.1.1 [H]

Molecular weight: Translated: 92226; Mature: 92226

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00102 PHOSPHORYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTNNIEKFDKAAFKASVKQHLVTTFAADEKTASAKVWYLAMGKALAELTTFDLVATEND
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHEEEECCCH
EKIKNARSVNYLSLEFLIGRLTGNNLISMGLYEEITEAMGELGYNLTDLLEEERDPALGN
HHHHHHCCCCEEEHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
GGLGRLAACFMDSLAAQEYPAIGYGLHYEYGLFRQSFEDGRQKEAPDAWCGVEGYPWEVA
CCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
RPDFAQQVGFYGHVETYTEKGQEKRRWVPGMSVEGMPWDLPIVGYQSDTVYPLRLWECRA
CCCHHHHCCCCCCHHHHHHCCHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEEEEECCC
KAPFSLASFNNGDYFEAQHALIDAGNVTKVLYPNDNHEKGKTLRLMQQYFHCACSIADIL
CCCEEEECCCCCCCCHHHHHEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
RRHDAAGHKIEDLSKYETIQLNDTHPTIGIPELMRVLIDVRGLSWDTAWEICSNTFAYTN
HHCCCCCCCHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCC
HTLLPEALETWSESLISRLLPRHMEIIYQINYLFLEGVKLKWPGDVDKLRKLSIIEEGTH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECEEEECCCCHHHHHHHHHHHHHHH
RMVRMANLCVVSSYAVNGVAALHSELVKRDLFPEFNEYFPGKLTNVTNGVTPRRWLKFCN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHHHHC
PGLSNLISGKIGNEWPAHLDQLSDIAVFADDEKFQKEFMAVKKQNKQRLANWVQENMGIE
CCHHHHHCCCCCCCCHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
LNTDAIFDVQIKRLHEYKRQHLDLLNILSLYHRILNEPGFDMHPRVFFFAAKAAPGYHLA
ECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHH
KEIIFAINKVAEKVNNDPRVSDLLKVVFIPDYRVSMAEIIIPAADVSEQISTAGKEASGT
HHHHHHHHHHHHHCCCCCCHHHHHHHEECCCCHHHHHHHEECCHHHHHHHHHCCCCCCCC
GNMKMALNGALTVGTMDGANVEIREEVGDENIFIFGLEVDEVEALKASGYSPYKYYEADS
CCEEEEEECEEEEEECCCCCEEEHHHCCCCCEEEEEEEHHHHHHHHHCCCCCCEECCHHH
LLQASLDLLAGDEFTPGKVGLLSAIRDNLLYGGDPYLVLADFADYVRAQNDIDAAYRDQK
HHHHHHHHHCCCCCCCCHHHHHHHHHHCCEECCCCCEEHHHHHHHHHCCCCHHHHHHHHH
QWAKMAILNTALVGKFSSDRSIRDYVNNIWKLESVNR
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKTNNIEKFDKAAFKASVKQHLVTTFAADEKTASAKVWYLAMGKALAELTTFDLVATEND
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHEEEECCCH
EKIKNARSVNYLSLEFLIGRLTGNNLISMGLYEEITEAMGELGYNLTDLLEEERDPALGN
HHHHHHCCCCEEEHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCC
GGLGRLAACFMDSLAAQEYPAIGYGLHYEYGLFRQSFEDGRQKEAPDAWCGVEGYPWEVA
CCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
RPDFAQQVGFYGHVETYTEKGQEKRRWVPGMSVEGMPWDLPIVGYQSDTVYPLRLWECRA
CCCHHHHCCCCCCHHHHHHCCHHHHHCCCCCCCCCCCCCCEEEECCCCCEEEEEEEECCC
KAPFSLASFNNGDYFEAQHALIDAGNVTKVLYPNDNHEKGKTLRLMQQYFHCACSIADIL
CCCEEEECCCCCCCCHHHHHEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
RRHDAAGHKIEDLSKYETIQLNDTHPTIGIPELMRVLIDVRGLSWDTAWEICSNTFAYTN
HHCCCCCCCHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCC
HTLLPEALETWSESLISRLLPRHMEIIYQINYLFLEGVKLKWPGDVDKLRKLSIIEEGTH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECEEEECCCCHHHHHHHHHHHHHHH
RMVRMANLCVVSSYAVNGVAALHSELVKRDLFPEFNEYFPGKLTNVTNGVTPRRWLKFCN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCHHHHHHHHC
PGLSNLISGKIGNEWPAHLDQLSDIAVFADDEKFQKEFMAVKKQNKQRLANWVQENMGIE
CCHHHHHCCCCCCCCHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
LNTDAIFDVQIKRLHEYKRQHLDLLNILSLYHRILNEPGFDMHPRVFFFAAKAAPGYHLA
ECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHH
KEIIFAINKVAEKVNNDPRVSDLLKVVFIPDYRVSMAEIIIPAADVSEQISTAGKEASGT
HHHHHHHHHHHHHCCCCCCHHHHHHHEECCCCHHHHHHHEECCHHHHHHHHHCCCCCCCC
GNMKMALNGALTVGTMDGANVEIREEVGDENIFIFGLEVDEVEALKASGYSPYKYYEADS
CCEEEEEECEEEEEECCCCCEEEHHHCCCCCEEEEEEEHHHHHHHHHCCCCCCEECCHHH
LLQASLDLLAGDEFTPGKVGLLSAIRDNLLYGGDPYLVLADFADYVRAQNDIDAAYRDQK
HHHHHHHHHCCCCCCCCHHHHHHHHHHCCEECCCCCEEHHHHHHHHHCCCCHHHHHHHHH
QWAKMAILNTALVGKFSSDRSIRDYVNNIWKLESVNR
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3037809; 9278503; 3155826; 2845225; 6283313; 6339728; 6986282; 9009262; 10220320; 10469642 [H]