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The map label for this gene is ydfG [C]

Identifier: 59713946

GI number: 59713946

Start: 859754

End: 860494

Strand: Reverse

Name: ydfG [C]

Synonym: VF_A0763

Alternate gene names: 59713946

Gene position: 860494-859754 (Counterclockwise)

Preceding gene: 59713947

Following gene: 59713945

Centisome position: 64.68

GC content: 37.25

Gene sequence:

>741_bases
ATGAGAAATGTATTAATCACAGGAGCCACTTCCGGAATTGGACTTTCTTTAGTTGAAAAATACCTACAAGCAGGTGACAA
AGTATATGCGTGTGGTCGTAATTTCCAAGCGTACCTAAAATCATCGTCGCTTATTGATGCAGAGAAGAGTGATAAGTTAG
TTAAAATTGTATTTGATATGAATCACCATGATGCAATTATAGATGTACTTACCGAGGTTGAGTCTTTAGATATTGCGATT
CTTAATGCTGGCACCTGTGAATACATTGATGATGCAATGGGATTTGACGCTGAGCTATTTGAGCGAGTCATCAATACTAA
TGTGATATCTATAGGTTATTGCTTGCAAGCGTTACTTCCTAAAATGAAACAAAAAGGTCATCTTGCATTAATGGGATCAA
GTGCTGCTTTTGTTCCCTTTCAACGTGCTGAAGCTTACGGAGCAAGTAAGGCTGCTATTCATTATTTAGCGCAATCACTG
CAATTGGATATACCAAAAGAAAGATTAACCATCAGTGTTATCGCCCCTGGTTTTGTAAAAACACCATTAACAGATAAAAA
TGATTTCCCCATGCCAATGTTGATAGAGCCGGATAAAGCCGCAGATCACATTATTAATGGAATTAATAACAATAAACAAC
ACATTCATTTTCCATTTCCTTTTACTCGTTTTCTCATCTTGATGGGGGCACTTCCTTCGTGTATTTGGCAATGGATGGCT
TTAAGGATGAAACGAAAATGA

Upstream 100 bases:

>100_bases
TTTTTTATCACAGAGATTTTCTTGATATGGGACAAATGGTTTACGAGCATTTGCCTCTTATTGGCCCTATGGTTAAGTTC
ATTAAAAAGAGGGTGCAAGC

Downstream 100 bases:

>100_bases
AAAAAATTGCCGTAGTTGGAACAGGTATTTCGGGCTTAGTTTGTGCACATTTATTAAGTCGAGAGCATCAAGTTACTGTA
TTTGAAGCCAATGATTACAT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MRNVLITGATSGIGLSLVEKYLQAGDKVYACGRNFQAYLKSSSLIDAEKSDKLVKIVFDMNHHDAIIDVLTEVESLDIAI
LNAGTCEYIDDAMGFDAELFERVINTNVISIGYCLQALLPKMKQKGHLALMGSSAAFVPFQRAEAYGASKAAIHYLAQSL
QLDIPKERLTISVIAPGFVKTPLTDKNDFPMPMLIEPDKAADHIINGINNNKQHIHFPFPFTRFLILMGALPSCIWQWMA
LRMKRK

Sequences:

>Translated_246_residues
MRNVLITGATSGIGLSLVEKYLQAGDKVYACGRNFQAYLKSSSLIDAEKSDKLVKIVFDMNHHDAIIDVLTEVESLDIAI
LNAGTCEYIDDAMGFDAELFERVINTNVISIGYCLQALLPKMKQKGHLALMGSSAAFVPFQRAEAYGASKAAIHYLAQSL
QLDIPKERLTISVIAPGFVKTPLTDKNDFPMPMLIEPDKAADHIINGINNNKQHIHFPFPFTRFLILMGALPSCIWQWMA
LRMKRK
>Mature_246_residues
MRNVLITGATSGIGLSLVEKYLQAGDKVYACGRNFQAYLKSSSLIDAEKSDKLVKIVFDMNHHDAIIDVLTEVESLDIAI
LNAGTCEYIDDAMGFDAELFERVINTNVISIGYCLQALLPKMKQKGHLALMGSSAAFVPFQRAEAYGASKAAIHYLAQSL
QLDIPKERLTISVIAPGFVKTPLTDKNDFPMPMLIEPDKAADHIINGINNNKQHIHFPFPFTRFLILMGALPSCIWQWMA
LRMKRK

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=199, Percent_Identity=30.1507537688442, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI33667109, Length=185, Percent_Identity=24.3243243243243, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI5031737, Length=187, Percent_Identity=22.9946524064171, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI32483357, Length=185, Percent_Identity=23.7837837837838, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=31.8681318681319, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI2367365, Length=196, Percent_Identity=27.5510204081633, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=188, Percent_Identity=24.468085106383, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=193, Percent_Identity=30.5699481865285, Blast_Score=75, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6323882, Length=193, Percent_Identity=30.0518134715026, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI23397609, Length=180, Percent_Identity=28.8888888888889, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21358495, Length=227, Percent_Identity=29.0748898678414, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI116007236, Length=212, Percent_Identity=27.8301886792453, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24584744, Length=193, Percent_Identity=23.8341968911917, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28574402, Length=193, Percent_Identity=23.8341968911917, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27345; Mature: 27345

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNVLITGATSGIGLSLVEKYLQAGDKVYACGRNFQAYLKSSSLIDAEKSDKLVKIVFDM
CCCEEEECCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHCCCCCCCCCCCCCEEEEEEEC
NHHDAIIDVLTEVESLDIAILNAGTCEYIDDAMGFDAELFERVINTNVISIGYCLQALLP
CCCHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHH
KMKQKGHLALMGSSAAFVPFQRAEAYGASKAAIHYLAQSLQLDIPKERLTISVIAPGFVK
HHHCCCCEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCHHHEEEEEECCCCEE
TPLTDKNDFPMPMLIEPDKAADHIINGINNNKQHIHFPFPFTRFLILMGALPSCIWQWMA
CCCCCCCCCCCCEEECCCHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
LRMKRK
HHHCCC
>Mature Secondary Structure
MRNVLITGATSGIGLSLVEKYLQAGDKVYACGRNFQAYLKSSSLIDAEKSDKLVKIVFDM
CCCEEEECCCCCCCHHHHHHHHHCCCEEEECCCCHHHHHCCCCCCCCCCCCCEEEEEEEC
NHHDAIIDVLTEVESLDIAILNAGTCEYIDDAMGFDAELFERVINTNVISIGYCLQALLP
CCCHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHH
KMKQKGHLALMGSSAAFVPFQRAEAYGASKAAIHYLAQSLQLDIPKERLTISVIAPGFVK
HHHCCCCEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCHHHEEEEEECCCCEE
TPLTDKNDFPMPMLIEPDKAADHIINGINNNKQHIHFPFPFTRFLILMGALPSCIWQWMA
CCCCCCCCCCCCEEECCCHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
LRMKRK
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730672 [H]