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The map label for this gene is yiaV [H]

Identifier: 59713926

GI number: 59713926

Start: 839032

End: 840099

Strand: Reverse

Name: yiaV [H]

Synonym: VF_A0743

Alternate gene names: 59713926

Gene position: 840099-839032 (Counterclockwise)

Preceding gene: 59713928

Following gene: 59713925

Centisome position: 63.15

GC content: 39.51

Gene sequence:

>1068_bases
ATGCAAGCTGCAGAACAAAAATTTAAACAATGGATGCGAATTCTAATTGTATTGTTTCTTATCGTTACCGCTTATTTAGT
GATGGCGGATAGACTCACACCATTAACGACTCAAAGTAAAGTTCAAGGGTTTGTTGTTCAAATTTCTCCTGAGGTGTCAG
GGCGTATTGTTGAAGTTAACCATACAAATAATCAGTTGGTTAAGAAAGGAGAGTTGTTATTTAAAATTGATGATGAAAAA
TATCTACTTGCTGTGCAAAAAGCGAAGATAGCGTTAGCGCAAGCAAAAGAACAAGAAGCATCATTAGTTGCAGATATAGA
GGCAGCACGATCAAATGTAAAGACAACACAAGTGACCGCGAATAATGCCAATCGTGAATATCATCGTATTAAGCGTTTAG
CGAATTCTGGCGCAGTTTCAGCTTCAGGTTTGGATTCAGCACTAACTAAACGAGATCAAGCGGCGGCGAACTTAATGGCA
GCAAAACAGAAAGTTCATGCTCTTGAAGTGAAGTTAGGCAAAGGGAATGGGCAAAGCAGTGCTGTGTTATCAGCGAAAAA
TAGCTTGAAACAAGCAGAGTTAGATTTAGAGCATACGCAAGTGGTTGCTCAGAATGAAGGGATTATTACCAATATGCAAT
TGCATGTGGGTGTGTTTGCAAATGCTAATCAACCATTATTGACTTTTATCCCAACGGATTCTCTGTGGGTTTCTGCCGAT
TACCGTGAGAAAGCAACTTCAGAAATGGTTAAAGGAATGAGAGCAGAAGTTGCTTACGATGCGATGCCTGGAGAGGTATT
TCCATTAATTGTAGAGAGCCGTGATTATGGTGTTGCTTCTGCACAACAAAAAGCCAATGGTCAATTAAGTAGTGTTGAAG
TCAGTAATCGTTGGGTGCGTGATGCACAACGTGTACGCGTTAATTTAACGAGCGATGAACCATTGTCTCCGAGATTATTT
GTTGGTTCGCGTGCAACCGTAATTATTTACACTTCAGGAAACAGTGTGATTGATTACATTGGCCATAGTTTAATTACCAT
GATCAGCTACTTACATTACATTTATTAG

Upstream 100 bases:

>100_bases
TATAGGTCTTATGTGTTCTATTTTGCCATCTATTCGTTTTGAAATCACGCCTTATAATGAGAGTTAGATCACGTCAATTT
TGGTTTTATCGAGAATATAT

Downstream 100 bases:

>100_bases
TGTGAGGCTTACATGAAAGCATTACGAATTTGGTTTGGTTGTGTTGTTGGATTTGCCATGTGCACGGTATTTGGCTGGTC
GAATGGTATGTTTGGTACCT

Product: multidrug resistance protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MQAAEQKFKQWMRILIVLFLIVTAYLVMADRLTPLTTQSKVQGFVVQISPEVSGRIVEVNHTNNQLVKKGELLFKIDDEK
YLLAVQKAKIALAQAKEQEASLVADIEAARSNVKTTQVTANNANREYHRIKRLANSGAVSASGLDSALTKRDQAAANLMA
AKQKVHALEVKLGKGNGQSSAVLSAKNSLKQAELDLEHTQVVAQNEGIITNMQLHVGVFANANQPLLTFIPTDSLWVSAD
YREKATSEMVKGMRAEVAYDAMPGEVFPLIVESRDYGVASAQQKANGQLSSVEVSNRWVRDAQRVRVNLTSDEPLSPRLF
VGSRATVIIYTSGNSVIDYIGHSLITMISYLHYIY

Sequences:

>Translated_355_residues
MQAAEQKFKQWMRILIVLFLIVTAYLVMADRLTPLTTQSKVQGFVVQISPEVSGRIVEVNHTNNQLVKKGELLFKIDDEK
YLLAVQKAKIALAQAKEQEASLVADIEAARSNVKTTQVTANNANREYHRIKRLANSGAVSASGLDSALTKRDQAAANLMA
AKQKVHALEVKLGKGNGQSSAVLSAKNSLKQAELDLEHTQVVAQNEGIITNMQLHVGVFANANQPLLTFIPTDSLWVSAD
YREKATSEMVKGMRAEVAYDAMPGEVFPLIVESRDYGVASAQQKANGQLSSVEVSNRWVRDAQRVRVNLTSDEPLSPRLF
VGSRATVIIYTSGNSVIDYIGHSLITMISYLHYIY
>Mature_355_residues
MQAAEQKFKQWMRILIVLFLIVTAYLVMADRLTPLTTQSKVQGFVVQISPEVSGRIVEVNHTNNQLVKKGELLFKIDDEK
YLLAVQKAKIALAQAKEQEASLVADIEAARSNVKTTQVTANNANREYHRIKRLANSGAVSASGLDSALTKRDQAAANLMA
AKQKVHALEVKLGKGNGQSSAVLSAKNSLKQAELDLEHTQVVAQNEGIITNMQLHVGVFANANQPLLTFIPTDSLWVSAD
YREKATSEMVKGMRAEVAYDAMPGEVFPLIVESRDYGVASAQQKANGQLSSVEVSNRWVRDAQRVRVNLTSDEPLSPRLF
VGSRATVIIYTSGNSVIDYIGHSLITMISYLHYIY

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790012, Length=343, Percent_Identity=25.0728862973761, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790024, Length=348, Percent_Identity=27.0114942528736, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790519, Length=301, Percent_Identity=30.2325581395349, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789041, Length=301, Percent_Identity=24.9169435215947, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI87081951, Length=302, Percent_Identity=27.4834437086093, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1789637, Length=328, Percent_Identity=27.7439024390244, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788711, Length=342, Percent_Identity=23.9766081871345, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39072; Mature: 39072

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAAEQKFKQWMRILIVLFLIVTAYLVMADRLTPLTTQSKVQGFVVQISPEVSGRIVEVN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEEEEEE
HTNNQLVKKGELLFKIDDEKYLLAVQKAKIALAQAKEQEASLVADIEAARSNVKTTQVTA
CCCCHHEECCCEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
NNANREYHRIKRLANSGAVSASGLDSALTKRDQAAANLMAAKQKVHALEVKLGKGNGQSS
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCC
AVLSAKNSLKQAELDLEHTQVVAQNEGIITNMQLHVGVFANANQPLLTFIPTDSLWVSAD
EEEHHHHHHHHHHCCHHHHEEEECCCCEEEEEEEEEEEEECCCCCEEEEECCCCEEEECC
YREKATSEMVKGMRAEVAYDAMPGEVFPLIVESRDYGVASAQQKANGQLSSVEVSNRWVR
HHHHHHHHHHHHHHHHHEECCCCCCEEEEEEECCCCCCCHHHHHCCCCEEEEEHHHHHHH
DAQRVRVNLTSDEPLSPRLFVGSRATVIIYTSGNSVIDYIGHSLITMISYLHYIY
CCEEEEEEECCCCCCCCEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQAAEQKFKQWMRILIVLFLIVTAYLVMADRLTPLTTQSKVQGFVVQISPEVSGRIVEVN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEEEEEE
HTNNQLVKKGELLFKIDDEKYLLAVQKAKIALAQAKEQEASLVADIEAARSNVKTTQVTA
CCCCHHEECCCEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
NNANREYHRIKRLANSGAVSASGLDSALTKRDQAAANLMAAKQKVHALEVKLGKGNGQSS
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCC
AVLSAKNSLKQAELDLEHTQVVAQNEGIITNMQLHVGVFANANQPLLTFIPTDSLWVSAD
EEEHHHHHHHHHHCCHHHHEEEECCCCEEEEEEEEEEEEECCCCCEEEEECCCCEEEECC
YREKATSEMVKGMRAEVAYDAMPGEVFPLIVESRDYGVASAQQKANGQLSSVEVSNRWVR
HHHHHHHHHHHHHHHHHEECCCCCCEEEEEEECCCCCCCHHHHHCCCCEEEEEHHHHHHH
DAQRVRVNLTSDEPLSPRLFVGSRATVIIYTSGNSVIDYIGHSLITMISYLHYIY
CCEEEEEEECCCCCCCCEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]