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The map label for this gene is lytS [H]

Identifier: 59713916

GI number: 59713916

Start: 829967

End: 831019

Strand: Reverse

Name: lytS [H]

Synonym: VF_A0733

Alternate gene names: 59713916

Gene position: 831019-829967 (Counterclockwise)

Preceding gene: 59713917

Following gene: 59713915

Centisome position: 62.47

GC content: 38.18

Gene sequence:

>1053_bases
ATGAGTGAGCGAAAAGAAACGATAATGCAATTAGTGAAAAGTTTGCTGATTACTACGCTGTTTTGTACAGTTATTGCCAT
GATGACGAGCAATATTTGGCCATCACCATTTTATGAGCATATCACTATTAGTTTAGGTTATGGCTACAGTGCTGTTTTAT
GCTCATTTGTCTTAGAGAATAATTTTCCCACTTTAAAAAAAGCCTACTCCACCGTATTAGCCATGGTGCTTTCTATCACA
TTAGGTACGTTTCACGCATCATTATGGCTAAATAAATATGAGGATTTCGCCACCTTAGAAGCACTCCAGCCCATCGTATT
ACTAGGATTGATCTTTACCGCTATCTGTTTCTATTACTTTCACGCAACTGAGAAAACCATGTTAGCAGAGCAAGCGTTGG
CACTCTCTAAGCGTAAACAGTTAGAGCAAGAAAAGGCGCTAGTATTAAGCCAGTTAAGTCAGCTTCAAAGTCAAATTGAG
CCACATTTTTTATTTAATACCTTAGCGAATATCAGCGCGTTAATTGAGTTAGACAGCAATAAAGCAAAATTGATGCTAGA
GAAACTGACGGATTTGCTGCGAGGATCGCTAAAGACAAACCGAAATCCATTAATTACCGTTGAGCAAGAAATTGAGCTAT
TAAATGCTTATTTATCGATTCAACAGATCCGTTTAGGAGATCGTTTAACGTATGAGATTGATAATCAGATAATTGAGTCT
ATTTCTCTGCCACCTCTGTTAATTCAGCCTCTGGTTGAAAATGCCATTACCCATGGTATAGAGCCGAGTGCGCAGGGAGG
GCAGCTTATGGTTCAGTTTAAGCAAGAGAATAATCAGTTTATTGTTGTTATCTCTGATAATGGAGTTGGATTGGAGTCAG
TACCGCCAAGTAAAGGACATGGGATGAGCTTAAATAATATCAAACAGCGATTATATGATTTGTTCGATGGCAGTGCTTCC
GTTCGTATTACTGAAAATAAAGATGGTGGTGTAAGTGCAGAGGTGACAATTCCATCGGATAAATTACTTCAATTAAATAG
GGAGTATTCATGA

Upstream 100 bases:

>100_bases
ATGGAACTGCCGCGCGTTTTTTAATAGGAAAAAGCGACTCAGCGTATGCAAATTTATCCGATAAGCATATGCTATTACTG
AATATAAAAGGACGATTCTA

Downstream 100 bases:

>100_bases
GTCAATCCATTACCGCCGTTATTGCCGATGATGAGCCATTATTACGCTTTCATTTAGAAAAAATGTTATCCGATCTTTGG
TTTGATTTAGATATTGTAGC

Product: two component sensor histidine kinase

Products: NA

Alternate protein names: Autolysin sensor kinase [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSERKETIMQLVKSLLITTLFCTVIAMMTSNIWPSPFYEHITISLGYGYSAVLCSFVLENNFPTLKKAYSTVLAMVLSIT
LGTFHASLWLNKYEDFATLEALQPIVLLGLIFTAICFYYFHATEKTMLAEQALALSKRKQLEQEKALVLSQLSQLQSQIE
PHFLFNTLANISALIELDSNKAKLMLEKLTDLLRGSLKTNRNPLITVEQEIELLNAYLSIQQIRLGDRLTYEIDNQIIES
ISLPPLLIQPLVENAITHGIEPSAQGGQLMVQFKQENNQFIVVISDNGVGLESVPPSKGHGMSLNNIKQRLYDLFDGSAS
VRITENKDGGVSAEVTIPSDKLLQLNREYS

Sequences:

>Translated_350_residues
MSERKETIMQLVKSLLITTLFCTVIAMMTSNIWPSPFYEHITISLGYGYSAVLCSFVLENNFPTLKKAYSTVLAMVLSIT
LGTFHASLWLNKYEDFATLEALQPIVLLGLIFTAICFYYFHATEKTMLAEQALALSKRKQLEQEKALVLSQLSQLQSQIE
PHFLFNTLANISALIELDSNKAKLMLEKLTDLLRGSLKTNRNPLITVEQEIELLNAYLSIQQIRLGDRLTYEIDNQIIES
ISLPPLLIQPLVENAITHGIEPSAQGGQLMVQFKQENNQFIVVISDNGVGLESVPPSKGHGMSLNNIKQRLYDLFDGSAS
VRITENKDGGVSAEVTIPSDKLLQLNREYS
>Mature_349_residues
SERKETIMQLVKSLLITTLFCTVIAMMTSNIWPSPFYEHITISLGYGYSAVLCSFVLENNFPTLKKAYSTVLAMVLSITL
GTFHASLWLNKYEDFATLEALQPIVLLGLIFTAICFYYFHATEKTMLAEQALALSKRKQLEQEKALVLSQLSQLQSQIEP
HFLFNTLANISALIELDSNKAKLMLEKLTDLLRGSLKTNRNPLITVEQEIELLNAYLSIQQIRLGDRLTYEIDNQIIESI
SLPPLLIQPLVENAITHGIEPSAQGGQLMVQFKQENNQFIVVISDNGVGLESVPPSKGHGMSLNNIKQRLYDLFDGSASV
RITENKDGGVSAEVTIPSDKLLQLNREYS

Specific function: Member of the two-component regulatory system lytR/lytS that probably regulates genes involved in cell wall metabolism [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=235, Percent_Identity=33.6170212765957, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1788446, Length=214, Percent_Identity=31.7757009345794, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39191; Mature: 39060

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERKETIMQLVKSLLITTLFCTVIAMMTSNIWPSPFYEHITISLGYGYSAVLCSFVLEN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEECCCHHHHHHHHHHHC
NFPTLKKAYSTVLAMVLSITLGTFHASLWLNKYEDFATLEALQPIVLLGLIFTAICFYYF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HATEKTMLAEQALALSKRKQLEQEKALVLSQLSQLQSQIEPHFLFNTLANISALIELDSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEECCC
KAKLMLEKLTDLLRGSLKTNRNPLITVEQEIELLNAYLSIQQIRLGDRLTYEIDNQIIES
HHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHH
ISLPPLLIQPLVENAITHGIEPSAQGGQLMVQFKQENNQFIVVISDNGVGLESVPPSKGH
CCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCC
GMSLNNIKQRLYDLFDGSASVRITENKDGGVSAEVTIPSDKLLQLNREYS
CCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCHHHHHCCCCCC
>Mature Secondary Structure 
SERKETIMQLVKSLLITTLFCTVIAMMTSNIWPSPFYEHITISLGYGYSAVLCSFVLEN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEECCCHHHHHHHHHHHC
NFPTLKKAYSTVLAMVLSITLGTFHASLWLNKYEDFATLEALQPIVLLGLIFTAICFYYF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HATEKTMLAEQALALSKRKQLEQEKALVLSQLSQLQSQIEPHFLFNTLANISALIELDSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEECCC
KAKLMLEKLTDLLRGSLKTNRNPLITVEQEIELLNAYLSIQQIRLGDRLTYEIDNQIIES
HHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHH
ISLPPLLIQPLVENAITHGIEPSAQGGQLMVQFKQENNQFIVVISDNGVGLESVPPSKGH
CCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCCCCCC
GMSLNNIKQRLYDLFDGSASVRITENKDGGVSAEVTIPSDKLLQLNREYS
CCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA