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The map label for this gene is abgR [H]

Identifier: 59713913

GI number: 59713913

Start: 826434

End: 827321

Strand: Reverse

Name: abgR [H]

Synonym: VF_A0730

Alternate gene names: 59713913

Gene position: 827321-826434 (Counterclockwise)

Preceding gene: 59713915

Following gene: 59713912

Centisome position: 62.19

GC content: 36.26

Gene sequence:

>888_bases
ATGGATAAATCATCACGCTATTTTTATGAAGTGGCTCGTCAAGGCAGCATTAAAGGCGCTTCTGAAAAACTGTTTATTAG
TCAACCGACATTAACGACAGCAATTAAGAAACTAGAAGAAAACTTAGATGTGATTTTGTTTCATCGAAAATCCAAAGGGG
TTGAACTGACAAGCTCTGGCTGGCTTTATTATCGTTATGTACAAGATTTGTTTGAAAAACACAGTCAAATGATGCATCAA
CTGACCGACATGAAAGCCAGAAGTCAGGGTAAGATAAAGTTAGGTATTGGTGAGGCGTGGTGGGAGTGTTTTGCTTCTGA
AGTGATTAAACAATTTGTGGAGCAGCATCCAAATAACTCAATGTATATCGAGTTTGGTAATGGCCTCTCTATGTTAAATC
AATTACTCAATGGTGATATTGATCTTTTTATCGGCCATGAAATTGAAAATATCGATCCAAGACATCGTGTATTGTTTATG
CCTTTATTTATCGAACAAGAAGCGTGGTTTGTAAGGGAAGGGCATCCATTGTTATCAAATGATCTAACATCAAATGAGTT
GGATAATTACCCTTTAATAAAAGTTACTCCTGATCACATCAGACACACGAAGATTTTGAATGATGAAGGTATGGAAGCGT
TCAATCTTAAACAGCAAAAAACAGGAGTTGTGTATGAACTTAACTCCTTAAAAGCCAGTATTGATATGCTAAAAACCAGT
GATGCGATCATGCCTTATACCGATCAAGTTAAAGAAAAAATGGCGGAGTTGGGAATTGTGACGCTTCCACAAGGATCAGA
AAAATCAGGCAGTGTTGGGATTTATACCAAAACAGAACAAGTATCAGAAAGTATTCAGTACTTAGTCTCATTATTAAAAG
GTAAATAA

Upstream 100 bases:

>100_bases
GAAAAAAAACGGTGATGAATAATTGATAATTTGAACTCTGATATAGAAAAAATTTATATCATGGGTATTGTGAAGTCAGA
ATAATTACTGAGTGTTTATT

Downstream 100 bases:

>100_bases
AGTAAAGATCGCCATGCGTTAAGACGATGTTTCAACGAAATATGTTACAGTGTGTAAATCTAAATATTAATAAGAGTCAC
TATCATGTCGAGCCTAGCTC

Product: DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MDKSSRYFYEVARQGSIKGASEKLFISQPTLTTAIKKLEENLDVILFHRKSKGVELTSSGWLYYRYVQDLFEKHSQMMHQ
LTDMKARSQGKIKLGIGEAWWECFASEVIKQFVEQHPNNSMYIEFGNGLSMLNQLLNGDIDLFIGHEIENIDPRHRVLFM
PLFIEQEAWFVREGHPLLSNDLTSNELDNYPLIKVTPDHIRHTKILNDEGMEAFNLKQQKTGVVYELNSLKASIDMLKTS
DAIMPYTDQVKEKMAELGIVTLPQGSEKSGSVGIYTKTEQVSESIQYLVSLLKGK

Sequences:

>Translated_295_residues
MDKSSRYFYEVARQGSIKGASEKLFISQPTLTTAIKKLEENLDVILFHRKSKGVELTSSGWLYYRYVQDLFEKHSQMMHQ
LTDMKARSQGKIKLGIGEAWWECFASEVIKQFVEQHPNNSMYIEFGNGLSMLNQLLNGDIDLFIGHEIENIDPRHRVLFM
PLFIEQEAWFVREGHPLLSNDLTSNELDNYPLIKVTPDHIRHTKILNDEGMEAFNLKQQKTGVVYELNSLKASIDMLKTS
DAIMPYTDQVKEKMAELGIVTLPQGSEKSGSVGIYTKTEQVSESIQYLVSLLKGK
>Mature_295_residues
MDKSSRYFYEVARQGSIKGASEKLFISQPTLTTAIKKLEENLDVILFHRKSKGVELTSSGWLYYRYVQDLFEKHSQMMHQ
LTDMKARSQGKIKLGIGEAWWECFASEVIKQFVEQHPNNSMYIEFGNGLSMLNQLLNGDIDLFIGHEIENIDPRHRVLFM
PLFIEQEAWFVREGHPLLSNDLTSNELDNYPLIKVTPDHIRHTKILNDEGMEAFNLKQQKTGVVYELNSLKASIDMLKTS
DAIMPYTDQVKEKMAELGIVTLPQGSEKSGSVGIYTKTEQVSESIQYLVSLLKGK

Specific function: Could be the regulator of the abg operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=262, Percent_Identity=31.6793893129771, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI157672245, Length=237, Percent_Identity=23.6286919831224, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI145693105, Length=193, Percent_Identity=29.5336787564767, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786202, Length=139, Percent_Identity=32.3741007194245, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87081904, Length=191, Percent_Identity=25.130890052356, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787530, Length=194, Percent_Identity=23.1958762886598, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33788; Mature: 33788

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKSSRYFYEVARQGSIKGASEKLFISQPTLTTAIKKLEENLDVILFHRKSKGVELTSSG
CCCCHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHCCCCEEEEEECCCCEEEECCC
WLYYRYVQDLFEKHSQMMHQLTDMKARSQGKIKLGIGEAWWECFASEVIKQFVEQHPNNS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCE
MYIEFGNGLSMLNQLLNGDIDLFIGHEIENIDPRHRVLFMPLFIEQEAWFVREGHPLLSN
EEEEECCCHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEEEEECCCEEEEECCCCCCCC
DLTSNELDNYPLIKVTPDHIRHTKILNDEGMEAFNLKQQKTGVVYELNSLKASIDMLKTS
CCCCCCCCCCCEEEECHHHHHHHEEECCCCCCHHCCHHHHCCEEEEHHHHHHHHHHHHCC
DAIMPYTDQVKEKMAELGIVTLPQGSEKSGSVGIYTKTEQVSESIQYLVSLLKGK
CCCCCCHHHHHHHHHHCCEEECCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDKSSRYFYEVARQGSIKGASEKLFISQPTLTTAIKKLEENLDVILFHRKSKGVELTSSG
CCCCHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHCCCCEEEEEECCCCEEEECCC
WLYYRYVQDLFEKHSQMMHQLTDMKARSQGKIKLGIGEAWWECFASEVIKQFVEQHPNNS
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCE
MYIEFGNGLSMLNQLLNGDIDLFIGHEIENIDPRHRVLFMPLFIEQEAWFVREGHPLLSN
EEEEECCCHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEEEEECCCEEEEECCCCCCCC
DLTSNELDNYPLIKVTPDHIRHTKILNDEGMEAFNLKQQKTGVVYELNSLKASIDMLKTS
CCCCCCCCCCCEEEECHHHHHHHEEECCCCCCHHCCHHHHCCEEEEHHHHHHHHHHHHCC
DAIMPYTDQVKEKMAELGIVTLPQGSEKSGSVGIYTKTEQVSESIQYLVSLLKGK
CCCCCCHHHHHHHHHHCCEEECCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9829935 [H]