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The map label for this gene is ygjR [H]

Identifier: 59713909

GI number: 59713909

Start: 823420

End: 824397

Strand: Reverse

Name: ygjR [H]

Synonym: VF_A0726

Alternate gene names: 59713909

Gene position: 824397-823420 (Counterclockwise)

Preceding gene: 59713910

Following gene: 59713907

Centisome position: 61.97

GC content: 38.75

Gene sequence:

>978_bases
ATGATAAAACTTGCTGTTATTGGAACTAACTGGATCACAGAACGATTTTTAGCGGCTGCACTAGAAAGTGGTAAATATCA
AATATCTGCAGTGTATTCACGCTCACTTGAACAAGCTAAAGCATTTGCAGATAAATTTAGTGTCACTTTAACCTTTGATT
GTTTAGATAAATTAGCGGCGTGTGATGAAGTAGATGCGGTGTACATCGCAAGTCCGAATTCATTTCATGCGCCACAATCT
ATTAAGATGATGAAGCATGGCAAACACGTCATTTGTGAAAAGCCAATCGCTTCAAATTATCAAGAAGCACAACTCGCTTA
TCAAACCGCACAAGAAAATAACGTGGTGCTGTTTGAAGCCTTTATGTCGCCATATTTACCTAACTTTCAGCAAATTAAGT
CGCACTTGCCAAGTTTAGGGGCTATTAGAAAAGCGCACATCACTTATTGTCAGTATTCTTCTCGTTACCCTAAATACCTT
AATGGTGAAAACCCAAATACTTTTAATCCTGAGTTTTCAAATGGCTCGATTATGGACATCGGTTTTTATTGTGTTGGTTC
TATGGTTGAGTTATTTGGTGAGCCAAAATCCATTCAAGCACAGGCGCATCTACTAGATTCAGGTGTTGATGGTAACGGCA
GTATCATTTGTGGTTATGATGGCTTTGATGTTGTTGTTATGCACTCTAAGACCAGTGATTCTTATGTACCTAGTGAGATT
CAAGGTGAAGAGGGGGCGATCTTAGCTGAGATGATCTCTATTGGCCAAAAAGTAACGAAAGTAAACCGTGGTGGAGAAAC
TGAAGACTTGACCCTTGAACAAAACGCCAATCCAATGTTTTATGAAGCGTTTAAATTTTCCGAGCAAGTTGAATCGAATC
AAATGGATATACAAGCGGTTGAGCGTTCATTGCTTATATCAAAAGTAACCTCAGAAATCCGCAAACAAACTGGTGTGGTT
TTTCCTGCTGATAAATAA

Upstream 100 bases:

>100_bases
CATTCGCAATTTTATGGTAACTGGTTGGGCGGGTGTTCAATTTAAAGCTCAGGCACTTCAAGCGAAATAAACAAAATAAA
ATCAATAAAGAGATAGGATC

Downstream 100 bases:

>100_bases
GATAAAATAAAAAGCCGAATGGTAAATACATTCGGCTTTGGTCTTAGTATTCTCACCCTTATGAGAATCTTTTATCTCAT
CGAGCGTTGTTAATTACTGT

Product: NAD-dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MIKLAVIGTNWITERFLAAALESGKYQISAVYSRSLEQAKAFADKFSVTLTFDCLDKLAACDEVDAVYIASPNSFHAPQS
IKMMKHGKHVICEKPIASNYQEAQLAYQTAQENNVVLFEAFMSPYLPNFQQIKSHLPSLGAIRKAHITYCQYSSRYPKYL
NGENPNTFNPEFSNGSIMDIGFYCVGSMVELFGEPKSIQAQAHLLDSGVDGNGSIICGYDGFDVVVMHSKTSDSYVPSEI
QGEEGAILAEMISIGQKVTKVNRGGETEDLTLEQNANPMFYEAFKFSEQVESNQMDIQAVERSLLISKVTSEIRKQTGVV
FPADK

Sequences:

>Translated_325_residues
MIKLAVIGTNWITERFLAAALESGKYQISAVYSRSLEQAKAFADKFSVTLTFDCLDKLAACDEVDAVYIASPNSFHAPQS
IKMMKHGKHVICEKPIASNYQEAQLAYQTAQENNVVLFEAFMSPYLPNFQQIKSHLPSLGAIRKAHITYCQYSSRYPKYL
NGENPNTFNPEFSNGSIMDIGFYCVGSMVELFGEPKSIQAQAHLLDSGVDGNGSIICGYDGFDVVVMHSKTSDSYVPSEI
QGEEGAILAEMISIGQKVTKVNRGGETEDLTLEQNANPMFYEAFKFSEQVESNQMDIQAVERSLLISKVTSEIRKQTGVV
FPADK
>Mature_325_residues
MIKLAVIGTNWITERFLAAALESGKYQISAVYSRSLEQAKAFADKFSVTLTFDCLDKLAACDEVDAVYIASPNSFHAPQS
IKMMKHGKHVICEKPIASNYQEAQLAYQTAQENNVVLFEAFMSPYLPNFQQIKSHLPSLGAIRKAHITYCQYSSRYPKYL
NGENPNTFNPEFSNGSIMDIGFYCVGSMVELFGEPKSIQAQAHLLDSGVDGNGSIICGYDGFDVVVMHSKTSDSYVPSEI
QGEEGAILAEMISIGQKVTKVNRGGETEDLTLEQNANPMFYEAFKFSEQVESNQMDIQAVERSLLISKVTSEIRKQTGVV
FPADK

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Homo sapiens, GI7657212, Length=347, Percent_Identity=23.9193083573487, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI145693182, Length=324, Percent_Identity=55.8641975308642, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI1787574, Length=205, Percent_Identity=24.390243902439, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24581117, Length=343, Percent_Identity=25.6559766763848, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24581115, Length=334, Percent_Identity=23.6526946107784, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24584727, Length=252, Percent_Identity=23.4126984126984, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35989; Mature: 35989

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLAVIGTNWITERFLAAALESGKYQISAVYSRSLEQAKAFADKFSVTLTFDCLDKLAA
CEEEEEECCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHC
CDEVDAVYIASPNSFHAPQSIKMMKHGKHVICEKPIASNYQEAQLAYQTAQENNVVLFEA
CCCCCEEEEECCCCCCCCHHHHHHHCCCEEEECCCHHCCHHHHHHHHHHCCCCCEEEEHH
FMSPYLPNFQQIKSHLPSLGAIRKAHITYCQYSSRYPKYLNGENPNTFNPEFSNGSIMDI
HHCCCCCCHHHHHHHCCHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEH
GFYCVGSMVELFGEPKSIQAQAHLLDSGVDGNGSIICGYDGFDVVVMHSKTSDSYVPSEI
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEECCCCCEEEEEECCCCCCCCCCCC
QGEEGAILAEMISIGQKVTKVNRGGETEDLTLEQNANPMFYEAFKFSEQVESNQMDIQAV
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCHHHHHH
ERSLLISKVTSEIRKQTGVVFPADK
HHHHHHHHHHHHHHHHCCCEECCCC
>Mature Secondary Structure
MIKLAVIGTNWITERFLAAALESGKYQISAVYSRSLEQAKAFADKFSVTLTFDCLDKLAA
CEEEEEECCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHEEEEEEHHHHHHHHC
CDEVDAVYIASPNSFHAPQSIKMMKHGKHVICEKPIASNYQEAQLAYQTAQENNVVLFEA
CCCCCEEEEECCCCCCCCHHHHHHHCCCEEEECCCHHCCHHHHHHHHHHCCCCCEEEEHH
FMSPYLPNFQQIKSHLPSLGAIRKAHITYCQYSSRYPKYLNGENPNTFNPEFSNGSIMDI
HHCCCCCCHHHHHHHCCHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEH
GFYCVGSMVELFGEPKSIQAQAHLLDSGVDGNGSIICGYDGFDVVVMHSKTSDSYVPSEI
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEEECCCCCEEEEEECCCCCCCCCCCC
QGEEGAILAEMISIGQKVTKVNRGGETEDLTLEQNANPMFYEAFKFSEQVESNQMDIQAV
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCHHHHHH
ERSLLISKVTSEIRKQTGVVFPADK
HHHHHHHHHHHHHHHHCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]