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The map label for this gene is 59713823

Identifier: 59713823

GI number: 59713823

Start: 716541

End: 716951

Strand: Reverse

Name: 59713823

Synonym: VF_A0640

Alternate gene names: NA

Gene position: 716951-716541 (Counterclockwise)

Preceding gene: 59713824

Following gene: 59713822

Centisome position: 53.89

GC content: 36.01

Gene sequence:

>411_bases
ATGAATAAGCCCATCGAACAAAGAATTGGTAACATCGCCTTAGTTGTTGAAAATTATGATGATGCAATTGAATTTTATAC
TAAAAAACTTCAATTTGAGCTTATCGAAGATACGGATTTAGGCGGTGGTAAGCGTTGGGTTCAAATATCTCCACCTAATT
CAACGGGTACAAATTTACTATTGGCTCAAGCAAGTAATGAAGAGCAATTAAAATCAGTTGGTAATCAAGCGGGTGGTCGT
GTTTTCTTATTTCTTCAAACCAATGACTTCTGGCGTGACTATGAGTTGATGAAAGCTCAAGGTGTCGAATTTACTGAAGA
ACCTCGTATTGAAGAGTACGGTACAGTTGTTGTATTTAAAGATTTATACGGTACAAAATGGGACTTATTGCAGCTAAATC
AAGCTAACTAA

Upstream 100 bases:

>100_bases
AATCGCATAGTAGTAAACGTGTTATGCAGGCGTTATATGCAAAATGAGTTTATGAGCTAAATAGGGTAGAATTCTATTTT
TGAACTGTAGTGAGCCGCAA

Downstream 100 bases:

>100_bases
GTTTGTAAGCACATAACAAATGCATCAACACGATTTGCTACACTCGGCGTTGTCAGTTTGCCTTTAGTTTTAGTGATTAA
GGCAGTAAAATTCAGCTAAG

Product: glyoxylase

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MNKPIEQRIGNIALVVENYDDAIEFYTKKLQFELIEDTDLGGGKRWVQISPPNSTGTNLLLAQASNEEQLKSVGNQAGGR
VFLFLQTNDFWRDYELMKAQGVEFTEEPRIEEYGTVVVFKDLYGTKWDLLQLNQAN

Sequences:

>Translated_136_residues
MNKPIEQRIGNIALVVENYDDAIEFYTKKLQFELIEDTDLGGGKRWVQISPPNSTGTNLLLAQASNEEQLKSVGNQAGGR
VFLFLQTNDFWRDYELMKAQGVEFTEEPRIEEYGTVVVFKDLYGTKWDLLQLNQAN
>Mature_136_residues
MNKPIEQRIGNIALVVENYDDAIEFYTKKLQFELIEDTDLGGGKRWVQISPPNSTGTNLLLAQASNEEQLKSVGNQAGGR
VFLFLQTNDFWRDYELMKAQGVEFTEEPRIEEYGTVVVFKDLYGTKWDLLQLNQAN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis ywkD [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 15566; Mature: 15566

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPIEQRIGNIALVVENYDDAIEFYTKKLQFELIEDTDLGGGKRWVQISPPNSTGTNLL
CCCCHHHHCCCEEEEEECCCHHHHHHHHHHEEEEEECCCCCCCCEEEEECCCCCCCCEEE
LAQASNEEQLKSVGNQAGGRVFLFLQTNDFWRDYELMKAQGVEFTEEPRIEEYGTVVVFK
EEECCCHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEE
DLYGTKWDLLQLNQAN
CCCCCEEEEEEEECCC
>Mature Secondary Structure
MNKPIEQRIGNIALVVENYDDAIEFYTKKLQFELIEDTDLGGGKRWVQISPPNSTGTNLL
CCCCHHHHCCCEEEEEECCCHHHHHHHHHHEEEEEECCCCCCCCEEEEECCCCCCCCEEE
LAQASNEEQLKSVGNQAGGRVFLFLQTNDFWRDYELMKAQGVEFTEEPRIEEYGTVVVFK
EEECCCHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEE
DLYGTKWDLLQLNQAN
CCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1333793 [H]