Click here to switch to the map view.

The map label for this gene is deoD2

Identifier: 59713585

GI number: 59713585

Start: 456946

End: 457656

Strand: Reverse

Name: deoD2

Synonym: VF_A0402

Alternate gene names: 59713585

Gene position: 457656-456946 (Counterclockwise)

Preceding gene: 59713588

Following gene: 59713584

Centisome position: 34.4

GC content: 41.35

Gene sequence:

>711_bases
ATGGCTACCCCACACATTAATGCTCAAGCTGGTGATTTCGCAGAAACAGTTCTAATGCCTGGTGACCCTCTTCGTGCAAA
GTTCATTGCTGAAAACTTCCTAGAAGACGTAAAGCAAGTATGTGACGTACGTAATATGTTCGGTTACACAGGTACTTACA
AAGGTAAAAAAGTATCTGTAATGGGCCACGGTATGGGTATCCCTTCATGTTGTATCTATGTTCACGAGTTAATCGCTGAA
TATGGTGTTAAAAACGTAATTCGTGTAGGTAGCTGTGGTGCGGTACACGATGACGTTAAACTGATGGATGTTGTTATCGG
TATGGGTGCATCAACTGACTCTAAAGTTAACCGTATCCGCTTTAACAATCATGACTTCGCTGCAATTGCTGATTTTGGTC
TACTAGAGACAGCTGTTGGTCAAGCTCGTGAGCTTAATGTTCCGGTTAAAGTTGGTAATGTATTCTCTGCTGACCTTTTC
TACTCACCAGAAGCTGATCTATTCGACAAAATGGAAAAATTAGGCATCCTTGGTGTTGATATGGAAGCGGCAGGCATTTA
TGGTGTGGCGGCTGACCTAGGAGCAAAAGCACTGACTATCCTTACTGTTTCTGATCACATTAAACGTGGTGAGAAATTAA
GCTCTGAAGACCGTCAAAAATCATTTAATGACATGATGACAGTTGCATTAGAAACTGCAATTAAACTGTAA

Upstream 100 bases:

>100_bases
GACACCTTAAAATATAGGCCTAAAATAGCCACATATCGAACAGGAATGTTCAACAATTTTAGTTACACTCAATTTTTATT
TGTAAACTGGAGACCTTATT

Downstream 100 bases:

>100_bases
TCAGATGTTTGCGCCAGTCATCAATACTGGCGCCATAAAATCCATAAGGGGAGTCTAGTGCCGACTGAAAAACTGCCGTT
GGCTGCTAAAGGGTTACAAC

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP 2

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MATPHINAQAGDFAETVLMPGDPLRAKFIAENFLEDVKQVCDVRNMFGYTGTYKGKKVSVMGHGMGIPSCCIYVHELIAE
YGVKNVIRVGSCGAVHDDVKLMDVVIGMGASTDSKVNRIRFNNHDFAAIADFGLLETAVGQARELNVPVKVGNVFSADLF
YSPEADLFDKMEKLGILGVDMEAAGIYGVAADLGAKALTILTVSDHIKRGEKLSSEDRQKSFNDMMTVALETAIKL

Sequences:

>Translated_236_residues
MATPHINAQAGDFAETVLMPGDPLRAKFIAENFLEDVKQVCDVRNMFGYTGTYKGKKVSVMGHGMGIPSCCIYVHELIAE
YGVKNVIRVGSCGAVHDDVKLMDVVIGMGASTDSKVNRIRFNNHDFAAIADFGLLETAVGQARELNVPVKVGNVFSADLF
YSPEADLFDKMEKLGILGVDMEAAGIYGVAADLGAKALTILTVSDHIKRGEKLSSEDRQKSFNDMMTVALETAIKL
>Mature_235_residues
ATPHINAQAGDFAETVLMPGDPLRAKFIAENFLEDVKQVCDVRNMFGYTGTYKGKKVSVMGHGMGIPSCCIYVHELIAEY
GVKNVIRVGSCGAVHDDVKLMDVVIGMGASTDSKVNRIRFNNHDFAAIADFGLLETAVGQARELNVPVKVGNVFSADLFY
SPEADLFDKMEKLGILGVDMEAAGIYGVAADLGAKALTILTVSDHIKRGEKLSSEDRQKSFNDMMTVALETAIKL

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family

Homologues:

Organism=Escherichia coli, GI1790844, Length=234, Percent_Identity=68.8034188034188, Blast_Score=342, Evalue=1e-95,
Organism=Escherichia coli, GI1790265, Length=238, Percent_Identity=26.0504201680672, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOD2_VIBF1 (Q5E0H4)

Other databases:

- EMBL:   CP000021
- RefSeq:   YP_206360.1
- ProteinModelPortal:   Q5E0H4
- SMR:   Q5E0H4
- STRING:   Q5E0H4
- GeneID:   3280648
- GenomeReviews:   CP000021_GR
- KEGG:   vfi:VF_A0402
- NMPDR:   fig|312309.3.peg.3060
- eggNOG:   COG0813
- HOGENOM:   HBG617197
- OMA:   DTIIRVG
- PhylomeDB:   Q5E0H4
- ProtClustDB:   PRK13374
- BioCyc:   VFIS312309:VFA0402-MONOMER
- HAMAP:   MF_01627
- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR000845
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR00107

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =2.4.2.1

Molecular weight: Translated: 25512; Mature: 25381

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPHINAQAGDFAETVLMPGDPLRAKFIAENFLEDVKQVCDVRNMFGYTGTYKGKKVSV
CCCCCCCCCCCCHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
MGHGMGIPSCCIYVHELIAEYGVKNVIRVGSCGAVHDDVKLMDVVIGMGASTDSKVNRIR
EECCCCCHHHHHHHHHHHHHHCHHHHEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEE
FNNHDFAAIADFGLLETAVGQARELNVPVKVGNVFSADLFYSPEADLFDKMEKLGILGVD
ECCCCCHHHHHHHHHHHHHCCHHCCCCCEEECCEEEECEEECCCHHHHHHHHHCCEEECC
MEAAGIYGVAADLGAKALTILTVSDHIKRGEKLSSEDRQKSFNDMMTVALETAIKL
CHHCCHHHHHHHCCCCEEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATPHINAQAGDFAETVLMPGDPLRAKFIAENFLEDVKQVCDVRNMFGYTGTYKGKKVSV
CCCCCCCCCCCHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
MGHGMGIPSCCIYVHELIAEYGVKNVIRVGSCGAVHDDVKLMDVVIGMGASTDSKVNRIR
EECCCCCHHHHHHHHHHHHHHCHHHHEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEE
FNNHDFAAIADFGLLETAVGQARELNVPVKVGNVFSADLFYSPEADLFDKMEKLGILGVD
ECCCCCHHHHHHHHHHHHHCCHHCCCCCEEECCEEEECEEECCCHHHHHHHHHCCEEECC
MEAAGIYGVAADLGAKALTILTVSDHIKRGEKLSSEDRQKSFNDMMTVALETAIKL
CHHCCHHHHHHHCCCCEEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA