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The map label for this gene is glnM [H]

Identifier: 59713573

GI number: 59713573

Start: 442353

End: 443213

Strand: Reverse

Name: glnM [H]

Synonym: VF_A0390

Alternate gene names: 59713573

Gene position: 443213-442353 (Counterclockwise)

Preceding gene: 59713574

Following gene: 59713569

Centisome position: 33.32

GC content: 37.4

Gene sequence:

>861_bases
ATGTATCAAAGAGCATCCTTTAGGCTCAATCGATTAGATTGGGGATTACTGATCATTATCATAGGGTTTGTCACTTGGTT
ATTGACCAAAGATAGTGGTACCTTGGCTTATCATTGGCAGTGGTCTAAAGCCATTCAGCTTTTATTTACTCCAAAAGCGG
ATGGTTCTCTCCCTTACTTTTTTGATGGTTTGTTTTCAACATTACGTTTAACGTTTTGGGGGATGCTCTTTGCCATTTGT
TTCGGTGTCTTATTAGGCTTAGGACGCCGTTCAAATTTTACTGTGATTAGAGCGTTATCAAATAGCTATATCCAACTGAT
CAGAAACATTCCACCTTTGGTCTTTATTTTCATATTTTACTTTTTTATTGCCAACCAACTGGTTCCTTTATTAGGTCTTG
AAAACTTATTACGCGAACACTCTGGTGATATTAACTTACTGCAACAATTTCTTTTTGGCTCAGCTAATCTGTGGGAGAAC
TTAACGGCGGGAGTATTGTGTATTGGTATGATCTCTGCCGCTTATATTGGTGAAGTCGTACGCTCAGGCTTGGATGCAAT
ACCTAAAGGTCAACATGAAGCAGCAAAAACACTGGGGTTATCAACTTGGCATCGATATCGATACATTATTGCCCCGCAAG
TATTTAAAGTGATCATTCCACCTCTAGCTGGACAATGTATCTCTTTAGTTAAAGATTCTTCTATTATCTCTTTAATTTCA
ATACAAGAGTTAACTTTTGTAGGTACTGAAATCGCGAACTCAAGCGGTATGATTTTTGAAATTTGGATTTTTGTAGCACT
TAGCTATTTCGTTCTCTGTTTTATTCTCTCTCAACTATTTAATTACTGGGAACGCCAATAG

Upstream 100 bases:

>100_bases
TGAGTGGATCAAAGCTCGTACCGATGACGGTTGGTTAAAAGAGCGTTACGACTATTGGTTTACAAGCCTAGATTGGCAAT
CACAAACAGCGAAATAAAAA

Downstream 100 bases:

>100_bases
CTAGCATAACTAAAAAAGCTCAAGAATACTCTTGAGCTTTTATATCAATTTAATTGATAGTTATACGTCAGTTACACTGT
AAACTTATTCATTATCTTTT

Product: amino acid ABC transporter permease protein

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MYQRASFRLNRLDWGLLIIIIGFVTWLLTKDSGTLAYHWQWSKAIQLLFTPKADGSLPYFFDGLFSTLRLTFWGMLFAIC
FGVLLGLGRRSNFTVIRALSNSYIQLIRNIPPLVFIFIFYFFIANQLVPLLGLENLLREHSGDINLLQQFLFGSANLWEN
LTAGVLCIGMISAAYIGEVVRSGLDAIPKGQHEAAKTLGLSTWHRYRYIIAPQVFKVIIPPLAGQCISLVKDSSIISLIS
IQELTFVGTEIANSSGMIFEIWIFVALSYFVLCFILSQLFNYWERQ

Sequences:

>Translated_286_residues
MYQRASFRLNRLDWGLLIIIIGFVTWLLTKDSGTLAYHWQWSKAIQLLFTPKADGSLPYFFDGLFSTLRLTFWGMLFAIC
FGVLLGLGRRSNFTVIRALSNSYIQLIRNIPPLVFIFIFYFFIANQLVPLLGLENLLREHSGDINLLQQFLFGSANLWEN
LTAGVLCIGMISAAYIGEVVRSGLDAIPKGQHEAAKTLGLSTWHRYRYIIAPQVFKVIIPPLAGQCISLVKDSSIISLIS
IQELTFVGTEIANSSGMIFEIWIFVALSYFVLCFILSQLFNYWERQ
>Mature_286_residues
MYQRASFRLNRLDWGLLIIIIGFVTWLLTKDSGTLAYHWQWSKAIQLLFTPKADGSLPYFFDGLFSTLRLTFWGMLFAIC
FGVLLGLGRRSNFTVIRALSNSYIQLIRNIPPLVFIFIFYFFIANQLVPLLGLENLLREHSGDINLLQQFLFGSANLWEN
LTAGVLCIGMISAAYIGEVVRSGLDAIPKGQHEAAKTLGLSTWHRYRYIIAPQVFKVIIPPLAGQCISLVKDSSIISLIS
IQELTFVGTEIANSSGMIFEIWIFVALSYFVLCFILSQLFNYWERQ

Specific function: Part of the ABC transporter complex glnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=250, Percent_Identity=28.4, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1788226, Length=231, Percent_Identity=29.4372294372294, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI87082239, Length=230, Percent_Identity=33.0434782608696, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787030, Length=231, Percent_Identity=28.5714285714286, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786874, Length=253, Percent_Identity=25.296442687747, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI48994930, Length=160, Percent_Identity=33.75, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787087, Length=178, Percent_Identity=27.5280898876405, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788645, Length=228, Percent_Identity=24.5614035087719, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788646, Length=225, Percent_Identity=22.2222222222222, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32516; Mature: 32516

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 9384377 [H]