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The map label for this gene is mdtA [H]

Identifier: 59713541

GI number: 59713541

Start: 402176

End: 403288

Strand: Reverse

Name: mdtA [H]

Synonym: VF_A0358

Alternate gene names: 59713541

Gene position: 403288-402176 (Counterclockwise)

Preceding gene: 59713544

Following gene: 59713540

Centisome position: 30.31

GC content: 40.43

Gene sequence:

>1113_bases
ATGCGTTCTACCACTTCTACATTAATGTTAATTAAAAAAACGGCCATTGCAGTAAGTCTTGCTGTTGGCTCCATGGTAAT
TTCTGGTTGTGACACTAATGAAGTAGCTAAAGAGATCTCACAACCAACAATTAGACCTGCACTCACTGAGATAGTATCTC
CTAGTGCTAACGCACAACTGCGTTTTAATGGCGTAGTTCGCTCTGCACAACGCGCAGACTTAGCTTTTAGAATGAGCAGT
CGCGTGATCAGTGTGTTGGTTGATGAAGGTCAACAAGTTAAAAAAGGGCAACTATTAGCTCAACTTGATCCTCGTGATGC
ACAAACAGCACTAGAATCTGCTCGTGTTGAATACAAAAACAGTAAAGCTGAATACACTCGTGGCAAAGCCATTTATGAAA
AAAGCCAAGCAATAGCAAAAAGTGATTTAGATACCTTAACCACTCGTTATCAACTAGCCAAAAATCGTCTAGATGAAGCA
CAACGCCAGCTTGAATATACGCAGTTACATGCACCATTTGATGGTGTGATTGGCAAAAAAATGATTGATAATCACGTCCA
AATTCAAGCGAATAGTCCAGTATTAACGGTTCATAATGTTGATGATTTAGAAGTACTCATCAATATTCCTGATAGCGTAA
TGTTAGGGGATTTAAAAGGCTCGAAAGCACTGGCTCAAATCAGTGCACTTCGTAATGAAACCTTCCCTCTTGTGCTAAGC
ACTTATGGAACGCAAGCGGACCCAATCACACAAACTTACCCTGTGGTTCTTACATTTGAAGATCTTCGTGGCTTCAATGT
ACTTCCAGGAATGACAGTTAAAGTCGTACCTGTTTATTCAGATGAACAAGATCAAGCGTCATTACTCATTACTGTTCCAC
TAACAGCGGTTGTTCCGGACAACCAAGGCGGTCAGTTTGTATGGGTTGTGACTCAAGAGAATAAAGTTCAAAAACGCATT
ATTAGCGCAGGTACCTTAGTATCAAATCGAATTGTCATTAATGATGGTTTGCAAACTGGTGAACGCATTATTACAGCAGG
GGCTTCTAGCTTAAAAGAAGGCATGGAAGTGAGACCATATACCGACACACTTTCTTCACAGGTTGAGAAATAA

Upstream 100 bases:

>100_bases
AGTTTTTACGTATAAAATAAACTCAAGAGTTTACTTTATAACTATAAAACTCCTTCAATCAATTTATTGGATTAATCGCT
CTTTCATGAGGACTGAGTAA

Downstream 100 bases:

>100_bases
CAAATGGATATCGCACGTTACACTATTGCTAAGCGTACCTCCGTGTGGGTGCTTATTGCGTTAATTTTATTTGGTGGCTA
TTTAAGTTACTTAAAACTCG

Product: acriflavin resistance periplasmic protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MRSTTSTLMLIKKTAIAVSLAVGSMVISGCDTNEVAKEISQPTIRPALTEIVSPSANAQLRFNGVVRSAQRADLAFRMSS
RVISVLVDEGQQVKKGQLLAQLDPRDAQTALESARVEYKNSKAEYTRGKAIYEKSQAIAKSDLDTLTTRYQLAKNRLDEA
QRQLEYTQLHAPFDGVIGKKMIDNHVQIQANSPVLTVHNVDDLEVLINIPDSVMLGDLKGSKALAQISALRNETFPLVLS
TYGTQADPITQTYPVVLTFEDLRGFNVLPGMTVKVVPVYSDEQDQASLLITVPLTAVVPDNQGGQFVWVVTQENKVQKRI
ISAGTLVSNRIVINDGLQTGERIITAGASSLKEGMEVRPYTDTLSSQVEK

Sequences:

>Translated_370_residues
MRSTTSTLMLIKKTAIAVSLAVGSMVISGCDTNEVAKEISQPTIRPALTEIVSPSANAQLRFNGVVRSAQRADLAFRMSS
RVISVLVDEGQQVKKGQLLAQLDPRDAQTALESARVEYKNSKAEYTRGKAIYEKSQAIAKSDLDTLTTRYQLAKNRLDEA
QRQLEYTQLHAPFDGVIGKKMIDNHVQIQANSPVLTVHNVDDLEVLINIPDSVMLGDLKGSKALAQISALRNETFPLVLS
TYGTQADPITQTYPVVLTFEDLRGFNVLPGMTVKVVPVYSDEQDQASLLITVPLTAVVPDNQGGQFVWVVTQENKVQKRI
ISAGTLVSNRIVINDGLQTGERIITAGASSLKEGMEVRPYTDTLSSQVEK
>Mature_370_residues
MRSTTSTLMLIKKTAIAVSLAVGSMVISGCDTNEVAKEISQPTIRPALTEIVSPSANAQLRFNGVVRSAQRADLAFRMSS
RVISVLVDEGQQVKKGQLLAQLDPRDAQTALESARVEYKNSKAEYTRGKAIYEKSQAIAKSDLDTLTTRYQLAKNRLDEA
QRQLEYTQLHAPFDGVIGKKMIDNHVQIQANSPVLTVHNVDDLEVLINIPDSVMLGDLKGSKALAQISALRNETFPLVLS
TYGTQADPITQTYPVVLTFEDLRGFNVLPGMTVKVVPVYSDEQDQASLLITVPLTAVVPDNQGGQFVWVVTQENKVQKRI
ISAGTLVSNRIVINDGLQTGERIITAGASSLKEGMEVRPYTDTLSSQVEK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=318, Percent_Identity=26.7295597484277, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789929, Length=301, Percent_Identity=26.2458471760797, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789665, Length=379, Percent_Identity=23.4828496042216, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40414; Mature: 40414

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSTTSTLMLIKKTAIAVSLAVGSMVISGCDTNEVAKEISQPTIRPALTEIVSPSANAQL
CCCCHHHHHEEEHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCHHHHHHHHHCCCCCCEE
RFNGVVRSAQRADLAFRMSSRVISVLVDEGQQVKKGQLLAQLDPRDAQTALESARVEYKN
EEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCC
SKAEYTRGKAIYEKSQAIAKSDLDTLTTRYQLAKNRLDEAQRQLEYTQLHAPFDGVIGKK
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
MIDNHVQIQANSPVLTVHNVDDLEVLINIPDSVMLGDLKGSKALAQISALRNETFPLVLS
HHCCEEEEEECCCEEEEECCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHCCCCEEEEE
TYGTQADPITQTYPVVLTFEDLRGFNVLPGMTVKVVPVYSDEQDQASLLITVPLTAVVPD
ECCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCEEEEEEEEEEEEEC
NQGGQFVWVVTQENKVQKRIISAGTLVSNRIVINDGLQTGERIITAGASSLKEGMEVRPY
CCCCEEEEEEECCCHHHHHHHHHCCEEECEEEEECCCCCCCCEEECCHHHHHCCCCCCCC
TDTLSSQVEK
HHHHHHHCCC
>Mature Secondary Structure
MRSTTSTLMLIKKTAIAVSLAVGSMVISGCDTNEVAKEISQPTIRPALTEIVSPSANAQL
CCCCHHHHHEEEHHHHHHHHHHHHHEEECCCHHHHHHHHCCCCHHHHHHHHHCCCCCCEE
RFNGVVRSAQRADLAFRMSSRVISVLVDEGQQVKKGQLLAQLDPRDAQTALESARVEYKN
EEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCC
SKAEYTRGKAIYEKSQAIAKSDLDTLTTRYQLAKNRLDEAQRQLEYTQLHAPFDGVIGKK
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
MIDNHVQIQANSPVLTVHNVDDLEVLINIPDSVMLGDLKGSKALAQISALRNETFPLVLS
HHCCEEEEEECCCEEEEECCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHCCCCEEEEE
TYGTQADPITQTYPVVLTFEDLRGFNVLPGMTVKVVPVYSDEQDQASLLITVPLTAVVPD
ECCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEEECCCCCCCEEEEEEEEEEEEEC
NQGGQFVWVVTQENKVQKRIISAGTLVSNRIVINDGLQTGERIITAGASSLKEGMEVRPY
CCCCEEEEEEECCCHHHHHHHHHCCEEECEEEEECCCCCCCCEEECCHHHHHCCCCCCCC
TDTLSSQVEK
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA