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The map label for this gene is setC [H]

Identifier: 59713211

GI number: 59713211

Start: 29782

End: 30981

Strand: Reverse

Name: setC [H]

Synonym: VF_A0028

Alternate gene names: 59713211

Gene position: 30981-29782 (Counterclockwise)

Preceding gene: 59713214

Following gene: 59713210

Centisome position: 2.33

GC content: 39.67

Gene sequence:

>1200_bases
ATGTATAAAGATAAAACCTCTTTACTATTTATTTTTACCGCTTTTATAACGGGGCTTTGCAGTGCATTTTTTTATCCACT
ATCAAGCCTATTCATTGTTGAAGAGCTAGATGCTTCACCAATGATGCTGAGTCTATATATGACACTTGCAGTCAGCAGTT
CAGTGATCGTATCTCAATTTATTGCTAAACGCTCAGACACGCATTGGAATCGTAAAACCATTCTGATGATATCACTAGCA
AGCTACTTAATTTTAGTCGCCAGTTTTACTGTTATTCGTGATTATTGGTTAGCGATTACCATGGCGGTCGTATTTGGGAG
CGTAAGTGGTGCTTCTTTTGGTCAACTGTTTGCTTTAGGTCGTGAATATGGTGACAGACACGTTACCAACAGCACCAGTT
TTTTAGCAACAATGCGAGCGGGTCTTGCCATAGCTTGGGTATTTGGCCCACCAGCAGCATTCATGCTTAAAGCACAATTT
GGATTCAGTGCAGCATTTGCTGTCTCTGCTATAACAGTATCAGTAGCAATACTGATCATTGCTAAATTTATTCCTGATAA
CGTCGTAACAAAAGAAGAAAAAACAGCCGCAATTACTGAACATAAGCCTCTCGGACGCATAGTAATCCTCTATTGTTTCA
TTATCGTCTGTGCCTTTTCAGCTAACAATTTGTACATTACAAGTATGCCTTTGTATCTTTCACAAGAGTTACAAGTGGAT
GTTAGTTGGTTAGGACTGATGTTTGGTGTGGCTGCAGCATGCGAGATCCCTGTGATGCTTGGAGCAGGAAAAATGGCTGA
GAAAATGGGTACAACCAGAGTAATGACCCTTGGTGTTATATCTGGCGCTATGTTCTTTCTTGTTATGCTTTCAAGCACCA
GCTTTACTTCAATGTTAATAGCTCAAATACTGAATGGTTTCTTTATTGGTGTTTGTGCAACGCTTGGTATGGTTGCATTA
CAAGATATGATGAAAGACAGATTAGGCACTGCGTCTACCCTATTCTCAAACATGTTGAATATCAGTGTGTTGGTATCCAG
TGTTTTAGTTGGTGTGGTAGGTGAACTATACAACTATTACAGCGCACTGTATTTATGCTTTATCGGTGCCATCATCGCAG
CAGTACTGTTGATTGTATTTGAAGTGTTAGAGAAGAAACAGAAAGTAAAAATCGAAGGACAATGCGAGATGGTTGGCTAA

Upstream 100 bases:

>100_bases
TCTAGCTCGAATAACATCAATTAATAGGCTCATCATTAAGTAGACTACCCGTAAAACCAAATGATCACTTAAACCACATT
TCGTATACTGGAATTGAGTT

Downstream 100 bases:

>100_bases
ATATAGTATTAACATACGCGCATACAAATTGTGCAATCTTTACATTTATATCGATAAAATAGTGCATACTAACTAGGGCG
TGTTGATCTTTTATGATTAA

Product: sugar efflux system

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MYKDKTSLLFIFTAFITGLCSAFFYPLSSLFIVEELDASPMMLSLYMTLAVSSSVIVSQFIAKRSDTHWNRKTILMISLA
SYLILVASFTVIRDYWLAITMAVVFGSVSGASFGQLFALGREYGDRHVTNSTSFLATMRAGLAIAWVFGPPAAFMLKAQF
GFSAAFAVSAITVSVAILIIAKFIPDNVVTKEEKTAAITEHKPLGRIVILYCFIIVCAFSANNLYITSMPLYLSQELQVD
VSWLGLMFGVAAACEIPVMLGAGKMAEKMGTTRVMTLGVISGAMFFLVMLSSTSFTSMLIAQILNGFFIGVCATLGMVAL
QDMMKDRLGTASTLFSNMLNISVLVSSVLVGVVGELYNYYSALYLCFIGAIIAAVLLIVFEVLEKKQKVKIEGQCEMVG

Sequences:

>Translated_399_residues
MYKDKTSLLFIFTAFITGLCSAFFYPLSSLFIVEELDASPMMLSLYMTLAVSSSVIVSQFIAKRSDTHWNRKTILMISLA
SYLILVASFTVIRDYWLAITMAVVFGSVSGASFGQLFALGREYGDRHVTNSTSFLATMRAGLAIAWVFGPPAAFMLKAQF
GFSAAFAVSAITVSVAILIIAKFIPDNVVTKEEKTAAITEHKPLGRIVILYCFIIVCAFSANNLYITSMPLYLSQELQVD
VSWLGLMFGVAAACEIPVMLGAGKMAEKMGTTRVMTLGVISGAMFFLVMLSSTSFTSMLIAQILNGFFIGVCATLGMVAL
QDMMKDRLGTASTLFSNMLNISVLVSSVLVGVVGELYNYYSALYLCFIGAIIAAVLLIVFEVLEKKQKVKIEGQCEMVG
>Mature_399_residues
MYKDKTSLLFIFTAFITGLCSAFFYPLSSLFIVEELDASPMMLSLYMTLAVSSSVIVSQFIAKRSDTHWNRKTILMISLA
SYLILVASFTVIRDYWLAITMAVVFGSVSGASFGQLFALGREYGDRHVTNSTSFLATMRAGLAIAWVFGPPAAFMLKAQF
GFSAAFAVSAITVSVAILIIAKFIPDNVVTKEEKTAAITEHKPLGRIVILYCFIIVCAFSANNLYITSMPLYLSQELQVD
VSWLGLMFGVAAACEIPVMLGAGKMAEKMGTTRVMTLGVISGAMFFLVMLSSTSFTSMLIAQILNGFFIGVCATLGMVAL
QDMMKDRLGTASTLFSNMLNISVLVSSVLVGVVGELYNYYSALYLCFIGAIIAAVLLIVFEVLEKKQKVKIEGQCEMVG

Specific function: Involved in the efflux of sugars. The physiological role may be the detoxification of non-metabolizable sugar analogs [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Set transporter family [H]

Homologues:

Organism=Escherichia coli, GI1790091, Length=382, Percent_Identity=31.413612565445, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI48994875, Length=369, Percent_Identity=30.0813008130081, Blast_Score=194, Evalue=9e-51,
Organism=Escherichia coli, GI1788495, Length=365, Percent_Identity=30.6849315068493, Blast_Score=186, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004750 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43366; Mature: 43366

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKDKTSLLFIFTAFITGLCSAFFYPLSSLFIVEELDASPMMLSLYMTLAVSSSVIVSQF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IAKRSDTHWNRKTILMISLASYLILVASFTVIRDYWLAITMAVVFGSVSGASFGQLFALG
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
REYGDRHVTNSTSFLATMRAGLAIAWVFGPPAAFMLKAQFGFSAAFAVSAITVSVAILII
HHHCCCCCCCCHHHHHHHHHCEEEEEEECCCHHHEEEECCCCHHHHHHHHHHHHHHHHHH
AKFIPDNVVTKEEKTAAITEHKPLGRIVILYCFIIVCAFSANNLYITSMPLYLSQELQVD
HHHCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHH
VSWLGLMFGVAAACEIPVMLGAGKMAEKMGTTRVMTLGVISGAMFFLVMLSSTSFTSMLI
HHHHHHHHHHHHHHCCCCEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AQILNGFFIGVCATLGMVALQDMMKDRLGTASTLFSNMLNISVLVSSVLVGVVGELYNYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SALYLCFIGAIIAAVLLIVFEVLEKKQKVKIEGQCEMVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCEEECC
>Mature Secondary Structure
MYKDKTSLLFIFTAFITGLCSAFFYPLSSLFIVEELDASPMMLSLYMTLAVSSSVIVSQF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
IAKRSDTHWNRKTILMISLASYLILVASFTVIRDYWLAITMAVVFGSVSGASFGQLFALG
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
REYGDRHVTNSTSFLATMRAGLAIAWVFGPPAAFMLKAQFGFSAAFAVSAITVSVAILII
HHHCCCCCCCCHHHHHHHHHCEEEEEEECCCHHHEEEECCCCHHHHHHHHHHHHHHHHHH
AKFIPDNVVTKEEKTAAITEHKPLGRIVILYCFIIVCAFSANNLYITSMPLYLSQELQVD
HHHCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHH
VSWLGLMFGVAAACEIPVMLGAGKMAEKMGTTRVMTLGVISGAMFFLVMLSSTSFTSMLI
HHHHHHHHHHHHHHCCCCEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AQILNGFFIGVCATLGMVALQDMMKDRLGTASTLFSNMLNISVLVSSVLVGVVGELYNYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SALYLCFIGAIIAAVLLIVFEVLEKKQKVKIEGQCEMVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503; 10209755; 10438463 [H]