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The map label for this gene is licR [H]

Identifier: 59713117

GI number: 59713117

Start: 2813546

End: 2815468

Strand: Direct

Name: licR [H]

Synonym: VF_2510

Alternate gene names: 59713117

Gene position: 2813546-2815468 (Clockwise)

Preceding gene: 59713116

Following gene: 59713120

Centisome position: 97.1

GC content: 37.23

Gene sequence:

>1923_bases
ATGATCCAACTGCCTTATCCTCGTCTTAATGTCATTTTTGAAGCGCTTAGATATGAAGCCCTTCCTCAGCAAGAGCTTGC
TCAGCGTTGTGATATTTCAACACGAACAATTCGAACAGACATCTCTGCCTTGAATGATATTTTGGCTTCTTACGGTGCCC
AAATTCAGCACCAGAGAGGAAAGGGCTATCACTTTGATATCTATGATGAGACCCGTTTTTTGGATATTGAAAAACAAACG
AAAAAAATGAAATCATCTCCTCGCAACGCCAAAGATCGTATGGTGTATTTGATGATGCGTCTATTATCTCAAGAGGAAGA
ATGTAAGTTGGATGATCTTGCCAATCAATGGTTTGTCAGTCGCACTTCATTACAAGCAGATATGGGAGAAATTAGAGAGC
AGCTTGAGCAATATAATTTAGAGTTAATAAGTAAAGCGCATTGTGGATTACGCCTGTTTGGTGAAGAGCAAGCAATTCGA
GCTTGTATCGCCCATATTTTATTCCAATTTAAACCAAGTGATCATACGTTTATTGATGTTTGCGAATATTTTTTCCCAGA
GATTAATCAACCATCCTTAAAAACGGATTTACTTGAATTAATTAATAAAAATCACATCAAGCTTACTGATGAAGGTTTGC
ATCATTTAGTGGTGTATTGTGGTGTTGCCCTGCATCGACTAAAACAAAACGCATGCATTCATCACGTAGATCAACCAAAT
CTCAGTGAAGAAGCACAAAAAACAGCAGCAGAGTTAAGCCAAACCATAGAAAGTTTACTTGGTGCACCTTTACCTCAAGC
AGAAATAGATTATCTAAGCATTCAAATTGCTGCTCGTCGAGTTACTGGCGTTCCTGAAATCGACACTCAAAAACCAACAG
AGCAATTAGAATTAACTCAATACTTATTGGATTACGTTAATACACATTACAACTACGATCTGCGTAATGATGAGCAATTA
AAACGAGACTTACTCTGCCATATAACCACCATGATCTTACGAGTTAAGTATCAAATTACCATTCCAAATCCACTATTTGA
TCATATAAAACGCTATTACCCATTGGCTTATGATATGACTGTTGCTGCTATTTCTCATTGGGGTAAACATTTAATTCCAG
ATGGTGAGATAGGTTACTTAGTTATGCATATTGGTGTTGGACTAGAGCGTAATTTCTCACTGGAAGAACAATTACCACCA
AAAGCTTTGCTTGTGTGTGACTCGGGAACATCAATTGTACGCTTACTTGAATCACAACTTATTCGCTCATTACCTCAACT
TACAATAGAAAAAGTAGAGAGTCTTAGAGATTATGAAGAGCTATCAAAAGTAGATGCTGATTTCGTTATCTCAACAGAAA
AAGTATCACAAAAAAACAAACCAACAATCACGGTATCTCCGATACCAACGAGCTTCCAATTAGAACAAGTAAATAAACTC
ATTCTAATGAATCGCTCACACCCATATATGTTGGATAAGTTTTTTGATCACCGTTATTTTTCTGTTCTGGATGAACCAAT
GACTCAAGGTGAAGTGCTCAAAAAATTCAGCGCTCATTTTACAGAAGATAACATCACCCCTATTGAGTTTTACGACTCAG
TTATTGAGCGAGAAAGCATTACATCGACAATTTTAGGGGAAGGCATTGCGATTCCACACTCTTTGGGATTACTCGCTAAC
GAGACCAAAGTATATACCATCATTTCTCCACACGGCGTAGATTGGGGGAACGGGAAAATAGCTCATGTAATTTTTCTTTT
TGCTATCAATAAAGACGATTATGAAGAAGCGATGAGCTTGTACGATTTATTTGTGACCTTCATGAATGGTAAAGCCGTCG
ATACCATCTTAGGCTGCCACTCTTATGATGAATTTCAATATGTTGCTAAAGAATGTTGGTTTAATCGAAAAAAAGATTGG
TAA

Upstream 100 bases:

>100_bases
TACATATACATCACATATTGAATAAATACCATTACCCTAACGTTTTCGTTGGTTGATATTATTATCAATATAAACACTTA
TTAACTGTTCTGGTTTTTCT

Downstream 100 bases:

>100_bases
ATAAAAAACCCCGGAACATGCCGGGGTTTTACATATCAACTAAATTGAACAATAAAAATTATCTGCGAGGCTTAAACTCA
AGCACTGGCGCTTTCTCTCC

Product: PTS system, mannitol (cryptic)-specific IIA component

Products: NA

Alternate protein names: Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MIQLPYPRLNVIFEALRYEALPQQELAQRCDISTRTIRTDISALNDILASYGAQIQHQRGKGYHFDIYDETRFLDIEKQT
KKMKSSPRNAKDRMVYLMMRLLSQEEECKLDDLANQWFVSRTSLQADMGEIREQLEQYNLELISKAHCGLRLFGEEQAIR
ACIAHILFQFKPSDHTFIDVCEYFFPEINQPSLKTDLLELINKNHIKLTDEGLHHLVVYCGVALHRLKQNACIHHVDQPN
LSEEAQKTAAELSQTIESLLGAPLPQAEIDYLSIQIAARRVTGVPEIDTQKPTEQLELTQYLLDYVNTHYNYDLRNDEQL
KRDLLCHITTMILRVKYQITIPNPLFDHIKRYYPLAYDMTVAAISHWGKHLIPDGEIGYLVMHIGVGLERNFSLEEQLPP
KALLVCDSGTSIVRLLESQLIRSLPQLTIEKVESLRDYEELSKVDADFVISTEKVSQKNKPTITVSPIPTSFQLEQVNKL
ILMNRSHPYMLDKFFDHRYFSVLDEPMTQGEVLKKFSAHFTEDNITPIEFYDSVIERESITSTILGEGIAIPHSLGLLAN
ETKVYTIISPHGVDWGNGKIAHVIFLFAINKDDYEEAMSLYDLFVTFMNGKAVDTILGCHSYDEFQYVAKECWFNRKKDW

Sequences:

>Translated_640_residues
MIQLPYPRLNVIFEALRYEALPQQELAQRCDISTRTIRTDISALNDILASYGAQIQHQRGKGYHFDIYDETRFLDIEKQT
KKMKSSPRNAKDRMVYLMMRLLSQEEECKLDDLANQWFVSRTSLQADMGEIREQLEQYNLELISKAHCGLRLFGEEQAIR
ACIAHILFQFKPSDHTFIDVCEYFFPEINQPSLKTDLLELINKNHIKLTDEGLHHLVVYCGVALHRLKQNACIHHVDQPN
LSEEAQKTAAELSQTIESLLGAPLPQAEIDYLSIQIAARRVTGVPEIDTQKPTEQLELTQYLLDYVNTHYNYDLRNDEQL
KRDLLCHITTMILRVKYQITIPNPLFDHIKRYYPLAYDMTVAAISHWGKHLIPDGEIGYLVMHIGVGLERNFSLEEQLPP
KALLVCDSGTSIVRLLESQLIRSLPQLTIEKVESLRDYEELSKVDADFVISTEKVSQKNKPTITVSPIPTSFQLEQVNKL
ILMNRSHPYMLDKFFDHRYFSVLDEPMTQGEVLKKFSAHFTEDNITPIEFYDSVIERESITSTILGEGIAIPHSLGLLAN
ETKVYTIISPHGVDWGNGKIAHVIFLFAINKDDYEEAMSLYDLFVTFMNGKAVDTILGCHSYDEFQYVAKECWFNRKKDW
>Mature_640_residues
MIQLPYPRLNVIFEALRYEALPQQELAQRCDISTRTIRTDISALNDILASYGAQIQHQRGKGYHFDIYDETRFLDIEKQT
KKMKSSPRNAKDRMVYLMMRLLSQEEECKLDDLANQWFVSRTSLQADMGEIREQLEQYNLELISKAHCGLRLFGEEQAIR
ACIAHILFQFKPSDHTFIDVCEYFFPEINQPSLKTDLLELINKNHIKLTDEGLHHLVVYCGVALHRLKQNACIHHVDQPN
LSEEAQKTAAELSQTIESLLGAPLPQAEIDYLSIQIAARRVTGVPEIDTQKPTEQLELTQYLLDYVNTHYNYDLRNDEQL
KRDLLCHITTMILRVKYQITIPNPLFDHIKRYYPLAYDMTVAAISHWGKHLIPDGEIGYLVMHIGVGLERNFSLEEQLPP
KALLVCDSGTSIVRLLESQLIRSLPQLTIEKVESLRDYEELSKVDADFVISTEKVSQKNKPTITVSPIPTSFQLEQVNKL
ILMNRSHPYMLDKFFDHRYFSVLDEPMTQGEVLKKFSAHFTEDNITPIEFYDSVIERESITSTILGEGIAIPHSLGLLAN
ETKVYTIISPHGVDWGNGKIAHVIFLFAINKDDYEEAMSLYDLFVTFMNGKAVDTILGCHSYDEFQYVAKECWFNRKKDW

Specific function: Positive regulator of the licABCH operon [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF00359 PTS_EIIA_2; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 73875; Mature: 73875

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQLPYPRLNVIFEALRYEALPQQELAQRCDISTRTIRTDISALNDILASYGAQIQHQRG
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCC
KGYHFDIYDETRFLDIEKQTKKMKSSPRNAKDRMVYLMMRLLSQEEECKLDDLANQWFVS
CCCEEEECCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RTSLQADMGEIREQLEQYNLELISKAHCGLRLFGEEQAIRACIAHILFQFKPSDHTFIDV
HHHHHHHHHHHHHHHHHHCHHHHHHHCCCEEEECHHHHHHHHHHHHHHHCCCCCCHHHHH
CEYFFPEINQPSLKTDLLELINKNHIKLTDEGLHHLVVYCGVALHRLKQNACIHHVDQPN
HHHHCCCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCEECCCCCC
LSEEAQKTAAELSQTIESLLGAPLPQAEIDYLSIQIAARRVTGVPEIDTQKPTEQLELTQ
CHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEEEHHHHCCCCCCCCCCCHHHHHHHH
YLLDYVNTHYNYDLRNDEQLKRDLLCHITTMILRVKYQITIPNPLFDHIKRYYPLAYDMT
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHCCCHHHHH
VAAISHWGKHLIPDGEIGYLVMHIGVGLERNFSLEEQLPPKALLVCDSGTSIVRLLESQL
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHCCCCCEEEEECCCHHHHHHHHHHH
IRSLPQLTIEKVESLRDYEELSKVDADFVISTEKVSQKNKPTITVSPIPTSFQLEQVNKL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHCCCCCCEEEEECCCCCHHHHHHCCE
ILMNRSHPYMLDKFFDHRYFSVLDEPMTQGEVLKKFSAHFTEDNITPIEFYDSVIERESI
EEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
TSTILGEGIAIPHSLGLLANETKVYTIISPHGVDWGNGKIAHVIFLFAINKDDYEEAMSL
HHHHHCCCCCCCHHHCCEECCCEEEEEECCCCCCCCCCCEEEEEEEEEECCCCHHHHHHH
YDLFVTFMNGKAVDTILGCHSYDEFQYVAKECWFNRKKDW
HHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIQLPYPRLNVIFEALRYEALPQQELAQRCDISTRTIRTDISALNDILASYGAQIQHQRG
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCC
KGYHFDIYDETRFLDIEKQTKKMKSSPRNAKDRMVYLMMRLLSQEEECKLDDLANQWFVS
CCCEEEECCCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
RTSLQADMGEIREQLEQYNLELISKAHCGLRLFGEEQAIRACIAHILFQFKPSDHTFIDV
HHHHHHHHHHHHHHHHHHCHHHHHHHCCCEEEECHHHHHHHHHHHHHHHCCCCCCHHHHH
CEYFFPEINQPSLKTDLLELINKNHIKLTDEGLHHLVVYCGVALHRLKQNACIHHVDQPN
HHHHCCCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCEECCCCCC
LSEEAQKTAAELSQTIESLLGAPLPQAEIDYLSIQIAARRVTGVPEIDTQKPTEQLELTQ
CHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEEEHHHHCCCCCCCCCCCHHHHHHHH
YLLDYVNTHYNYDLRNDEQLKRDLLCHITTMILRVKYQITIPNPLFDHIKRYYPLAYDMT
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHCCCHHHHH
VAAISHWGKHLIPDGEIGYLVMHIGVGLERNFSLEEQLPPKALLVCDSGTSIVRLLESQL
HHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHCCCCCEEEEECCCHHHHHHHHHHH
IRSLPQLTIEKVESLRDYEELSKVDADFVISTEKVSQKNKPTITVSPIPTSFQLEQVNKL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHCCCCCCEEEEECCCCCHHHHHHCCE
ILMNRSHPYMLDKFFDHRYFSVLDEPMTQGEVLKKFSAHFTEDNITPIEFYDSVIERESI
EEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
TSTILGEGIAIPHSLGLLANETKVYTIISPHGVDWGNGKIAHVIFLFAINKDDYEEAMSL
HHHHHCCCCCCCHHHCCEECCCEEEEEECCCCCCCCCCCEEEEEEEEEECCCCHHHHHHH
YDLFVTFMNGKAVDTILGCHSYDEFQYVAKECWFNRKKDW
HHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377; 10438772 [H]