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The map label for this gene is gspH [H]

Identifier: 59713077

GI number: 59713077

Start: 2766380

End: 2766976

Strand: Reverse

Name: gspH [H]

Synonym: VF_2470

Alternate gene names: 59713077

Gene position: 2766976-2766380 (Counterclockwise)

Preceding gene: 59713078

Following gene: 59713076

Centisome position: 95.49

GC content: 43.05

Gene sequence:

>597_bases
ATGAAAATAAAACGTGAGGTTGGGTTTACCCTGATCGAAATAATGTTGGTATTGGTACTGTTATCGCTCAGTGCGATGGC
CGTTATCATGAGCCTTCCTGATAATCAGGATGACCAGCTGGAGGAAGAAGCCTCACGTTTTTATCAACTTGTTCAACTCC
TTAATGAGGATGCTTTGCTCAATGGGATGGATTACGGCATTTACTTTAATCAAGAGCGACAAGAATACCGCTTTATGCAA
TTAATGGTAGATGGTTGGCAGCCAATTGAGAAAAGCCGCTTTTTTACAGAAGTGAAATTGGAAGAGTCGCTAGAGTTTGA
TATGACGCTTGGTGGTTCAGCTTGGGCAGATGATGAGCGACTCTTTGAGCCGGGCTCTTTATTTGATGAAGAGATGTTTG
CGGATGTCGAAAAAGGTAAAAAGCCAACACCTCCTCAAGTCATGGTGCTTTCAAGTGGTGAAGTGACTCCTTTTTCGTTT
CGTTTATCTCCGCAAGGTGCTCGTGGAAACCTTGATGATAAATCATGGCTTATTCGCGTTGAAGAATCCGGAGTGATTAA
ATTATTTGCTCCGGGGGAGGAACGTGATGAGGAATAA

Upstream 100 bases:

>100_bases
CTAGGTGCTGATGGTCAAGAAGGCGGTGAAGGTGCGAATGCGGATATTGGTAACTGGAACATGCAAGACTTTCAATAAGT
CTTCATAAATAAGAACAGTG

Downstream 100 bases:

>100_bases
GACATATCAGCGAACTTCTTCTAAAGGCATGACATTACTTGAAGTCTTAGTTGCGCTTGCTATTTTCGCAACTGCAGCCC
TAAGTGTGTTGCGCTCGGTG

Product: general secretion pathway protein H

Products: NA

Alternate protein names: Cholera toxin secretion protein epsH [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MKIKREVGFTLIEIMLVLVLLSLSAMAVIMSLPDNQDDQLEEEASRFYQLVQLLNEDALLNGMDYGIYFNQERQEYRFMQ
LMVDGWQPIEKSRFFTEVKLEESLEFDMTLGGSAWADDERLFEPGSLFDEEMFADVEKGKKPTPPQVMVLSSGEVTPFSF
RLSPQGARGNLDDKSWLIRVEESGVIKLFAPGEERDEE

Sequences:

>Translated_198_residues
MKIKREVGFTLIEIMLVLVLLSLSAMAVIMSLPDNQDDQLEEEASRFYQLVQLLNEDALLNGMDYGIYFNQERQEYRFMQ
LMVDGWQPIEKSRFFTEVKLEESLEFDMTLGGSAWADDERLFEPGSLFDEEMFADVEKGKKPTPPQVMVLSSGEVTPFSF
RLSPQGARGNLDDKSWLIRVEESGVIKLFAPGEERDEE
>Mature_198_residues
MKIKREVGFTLIEIMLVLVLLSLSAMAVIMSLPDNQDDQLEEEASRFYQLVQLLNEDALLNGMDYGIYFNQERQEYRFMQ
LMVDGWQPIEKSRFFTEVKLEESLEFDMTLGGSAWADDERLFEPGSLFDEEMFADVEKGKKPTPPQVMVLSSGEVTPFSF
RLSPQGARGNLDDKSWLIRVEESGVIKLFAPGEERDEE

Specific function: Required for secretion of cholera toxin through the outer membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP H family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002416
- InterPro:   IPR012902
- InterPro:   IPR001120
- InterPro:   IPR022346 [H]

Pfam domain/function: PF12019 GspH [H]

EC number: NA

Molecular weight: Translated: 22751; Mature: 22751

Theoretical pI: Translated: 4.02; Mature: 4.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKREVGFTLIEIMLVLVLLSLSAMAVIMSLPDNQDDQLEEEASRFYQLVQLLNEDALL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHC
NGMDYGIYFNQERQEYRFMQLMVDGWQPIEKSRFFTEVKLEESLEFDMTLGGSAWADDER
CCCCCCEEECCHHHHHHHHHHHHCCCCCHHHHHHHEEEECCCCCEEEEEECCCCCCCCCC
LFEPGSLFDEEMFADVEKGKKPTPPQVMVLSSGEVTPFSFRLSPQGARGNLDDKSWLIRV
CCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCEEEEEE
EESGVIKLFAPGEERDEE
CCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MKIKREVGFTLIEIMLVLVLLSLSAMAVIMSLPDNQDDQLEEEASRFYQLVQLLNEDALL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHC
NGMDYGIYFNQERQEYRFMQLMVDGWQPIEKSRFFTEVKLEESLEFDMTLGGSAWADDER
CCCCCCEEECCHHHHHHHHHHHHCCCCCHHHHHHHEEEECCCCCEEEEEECCCCCCCCCC
LFEPGSLFDEEMFADVEKGKKPTPPQVMVLSSGEVTPFSFRLSPQGARGNLDDKSWLIRV
CCCCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCEEEEEE
EESGVIKLFAPGEERDEE
CCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]