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The map label for this gene is dinF [H]

Identifier: 59713047

GI number: 59713047

Start: 2740425

End: 2741756

Strand: Reverse

Name: dinF [H]

Synonym: VF_2440

Alternate gene names: 59713047

Gene position: 2741756-2740425 (Counterclockwise)

Preceding gene: 59713048

Following gene: 172087777

Centisome position: 94.62

GC content: 38.14

Gene sequence:

>1332_bases
ATGTGGAATTCATTAAGAAACCTTTCATTACATCGGCAAGTGCTAGCATTAGCTATTCCGATGGTGCTATCAAATATCAC
TATTCCTTTATTAGGATTAATTGATGTTGCTGTTATTGGGCATTTAGAGCATGCTTGGTATTTAGGTGGTGTAGCGGTGG
GCGGCACAATGATCAGTGTGACGTTTTGGTTATTGGGTTTTCTTCGCATGGCAACAACAGGATTAACCGCTCAAGCTTAT
GGTGCAGAAAATAAAAATGCGTTGAGTCAGACGTTTTCTCAAGGTATTTTTCTTGCTTTGTGCTTCTCTTTTATTTTACT
GCTTTTTCATCAGCCACTTTCTCAGATCATTTTTTCATTCAGTGACGCTTCTGTTGAAGTGAAGCACTATGCCGAGCAAT
ATTTTTCTATTCGTATATGGAGTGCGCCAGCAGCATTAAGTAATTTGGTTATCATGGGCTGGTTACTGGGTACGCAAAAT
GCTCGTTATCCTATGTGGCTAGTTATCATAACCAATAGCATTAATATTATTCTCGATCTTTTGTTTGTGGTTGGTTTTCA
TTGGAAAGTTGAAGGTGCGGCACTTGCTTCCGTCATTGCCGATTATTCTTCATTAGTAATCGGTTTGTGGTTTGTCTTAA
AACAGAGTAATAAGCTCGTGTTACCTAGCTTTATTATGTCGCTATCTGATTTATTATCGGGTTTTAAGCGTCTCTTGAAT
TTAAATCGAGATATATTCTTACGTTCTCTGTGCTTACAAGCTTGCTTTACTTTTATGACGTTTCAAGGAGCATCATTAGG
TGTAGATATTGTTGCTGCAAATGCAGTATTAATGAGCTTCTTAATGATGATTTCTTATGGTATGGATGGGTTTGCTTATG
CAATGGAGGCAATGGTAGGAAAGGCGATTGGAGCAAAAAGTAGAACTCAGCTAACGGATTCTCTTATTGGTACGACTTTT
TGGAGTTTAGTGATAAGTAGCTTACTCAGTTTGGTATTTGGTGTATTTGGTTATCAGTTAATCGCAATGATATCTTCAAT
TGAAGATGTGCAAAAAACAGCGTTGATTTATTTGCCTTGGTTAATTGCCATGCCATTGGTATCAATGTGGTGTTTCTTGT
TGGATGGTATTTTTGTTGGAGCAACCAAAGGCTCTGAGATGAGAAATTCCATGTTTATCGCCATGATAACCTTCTTCTCT
GTTTGGTGGTTAATGCAAGATAACGGAAATCATGCGCTTTGGGCGGCTATGATTTCATTTATGGCAATGCGGGGGGTGAG
TTTGGCTGTGACATTCTATTATCAATGGAAAAAAGCAATTTTCCTATCATAG

Upstream 100 bases:

>100_bases
GTTTCTATTTAATGACAAGAGTATGAATTGAAGGGTGCAGGGTTTAGGATCATAAGAAAGTAAGCAATAATGTGACTACT
TTTTTCTATCGGTACTCCCT

Downstream 100 bases:

>100_bases
GCCAAATGCGTTACCTAATTGATAGTTATACAAAAAAATGGCTGCAGCATGCAGCCCTTTTTTATAATTAGAATAATCTA
TTTAGACCATTGAGTGCGGC

Product: DNA-damage-inducible SOS response protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MWNSLRNLSLHRQVLALAIPMVLSNITIPLLGLIDVAVIGHLEHAWYLGGVAVGGTMISVTFWLLGFLRMATTGLTAQAY
GAENKNALSQTFSQGIFLALCFSFILLLFHQPLSQIIFSFSDASVEVKHYAEQYFSIRIWSAPAALSNLVIMGWLLGTQN
ARYPMWLVIITNSINIILDLLFVVGFHWKVEGAALASVIADYSSLVIGLWFVLKQSNKLVLPSFIMSLSDLLSGFKRLLN
LNRDIFLRSLCLQACFTFMTFQGASLGVDIVAANAVLMSFLMMISYGMDGFAYAMEAMVGKAIGAKSRTQLTDSLIGTTF
WSLVISSLLSLVFGVFGYQLIAMISSIEDVQKTALIYLPWLIAMPLVSMWCFLLDGIFVGATKGSEMRNSMFIAMITFFS
VWWLMQDNGNHALWAAMISFMAMRGVSLAVTFYYQWKKAIFLS

Sequences:

>Translated_443_residues
MWNSLRNLSLHRQVLALAIPMVLSNITIPLLGLIDVAVIGHLEHAWYLGGVAVGGTMISVTFWLLGFLRMATTGLTAQAY
GAENKNALSQTFSQGIFLALCFSFILLLFHQPLSQIIFSFSDASVEVKHYAEQYFSIRIWSAPAALSNLVIMGWLLGTQN
ARYPMWLVIITNSINIILDLLFVVGFHWKVEGAALASVIADYSSLVIGLWFVLKQSNKLVLPSFIMSLSDLLSGFKRLLN
LNRDIFLRSLCLQACFTFMTFQGASLGVDIVAANAVLMSFLMMISYGMDGFAYAMEAMVGKAIGAKSRTQLTDSLIGTTF
WSLVISSLLSLVFGVFGYQLIAMISSIEDVQKTALIYLPWLIAMPLVSMWCFLLDGIFVGATKGSEMRNSMFIAMITFFS
VWWLMQDNGNHALWAAMISFMAMRGVSLAVTFYYQWKKAIFLS
>Mature_443_residues
MWNSLRNLSLHRQVLALAIPMVLSNITIPLLGLIDVAVIGHLEHAWYLGGVAVGGTMISVTFWLLGFLRMATTGLTAQAY
GAENKNALSQTFSQGIFLALCFSFILLLFHQPLSQIIFSFSDASVEVKHYAEQYFSIRIWSAPAALSNLVIMGWLLGTQN
ARYPMWLVIITNSINIILDLLFVVGFHWKVEGAALASVIADYSSLVIGLWFVLKQSNKLVLPSFIMSLSDLLSGFKRLLN
LNRDIFLRSLCLQACFTFMTFQGASLGVDIVAANAVLMSFLMMISYGMDGFAYAMEAMVGKAIGAKSRTQLTDSLIGTTF
WSLVISSLLSLVFGVFGYQLIAMISSIEDVQKTALIYLPWLIAMPLVSMWCFLLDGIFVGATKGSEMRNSMFIAMITFFS
VWWLMQDNGNHALWAAMISFMAMRGVSLAVTFYYQWKKAIFLS

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=426, Percent_Identity=48.1220657276995, Blast_Score=339, Evalue=3e-94,
Organism=Escherichia coli, GI226510954, Length=446, Percent_Identity=23.7668161434978, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 49214; Mature: 49214

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWNSLRNLSLHRQVLALAIPMVLSNITIPLLGLIDVAVIGHLEHAWYLGGVAVGGTMISV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
TFWLLGFLRMATTGLTAQAYGAENKNALSQTFSQGIFLALCFSFILLLFHQPLSQIIFSF
HHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDASVEVKHYAEQYFSIRIWSAPAALSNLVIMGWLLGTQNARYPMWLVIITNSINIILDL
CCCCHHHHHHHHHHHEEEEEECHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHH
LFVVGFHWKVEGAALASVIADYSSLVIGLWFVLKQSNKLVLPSFIMSLSDLLSGFKRLLN
HHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHH
LNRDIFLRSLCLQACFTFMTFQGASLGVDIVAANAVLMSFLMMISYGMDGFAYAMEAMVG
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KAIGAKSRTQLTDSLIGTTFWSLVISSLLSLVFGVFGYQLIAMISSIEDVQKTALIYLPW
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAMPLVSMWCFLLDGIFVGATKGSEMRNSMFIAMITFFSVWWLMQDNGNHALWAAMISF
HHHHHHHHHHHHHHCCHHEECCCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHH
MAMRGVSLAVTFYYQWKKAIFLS
HHHCCCCEEEEEHHHHHHHHCCC
>Mature Secondary Structure
MWNSLRNLSLHRQVLALAIPMVLSNITIPLLGLIDVAVIGHLEHAWYLGGVAVGGTMISV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
TFWLLGFLRMATTGLTAQAYGAENKNALSQTFSQGIFLALCFSFILLLFHQPLSQIIFSF
HHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SDASVEVKHYAEQYFSIRIWSAPAALSNLVIMGWLLGTQNARYPMWLVIITNSINIILDL
CCCCHHHHHHHHHHHEEEEEECHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHH
LFVVGFHWKVEGAALASVIADYSSLVIGLWFVLKQSNKLVLPSFIMSLSDLLSGFKRLLN
HHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHH
LNRDIFLRSLCLQACFTFMTFQGASLGVDIVAANAVLMSFLMMISYGMDGFAYAMEAMVG
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KAIGAKSRTQLTDSLIGTTFWSLVISSLLSLVFGVFGYQLIAMISSIEDVQKTALIYLPW
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAMPLVSMWCFLLDGIFVGATKGSEMRNSMFIAMITFFSVWWLMQDNGNHALWAAMISF
HHHHHHHHHHHHHHCCHHEECCCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHH
MAMRGVSLAVTFYYQWKKAIFLS
HHHCCCCEEEEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]