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The map label for this gene is coaA [H]

Identifier: 59713031

GI number: 59713031

Start: 2709741

End: 2710664

Strand: Direct

Name: coaA [H]

Synonym: VF_2424

Alternate gene names: 59713031

Gene position: 2709741-2710664 (Clockwise)

Preceding gene: 59713017

Following gene: 59713034

Centisome position: 93.52

GC content: 34.63

Gene sequence:

>924_bases
GTGAACTCTTATTTAACATTTACTCGTGAGCATTGGGCTGAATTGAGAAAATCAACGCCTATGACACTTACAGAAAAAGA
GTTAACGAGCTTACGAGGCATCAATGAAAATATAAGCATTGATGAAGTGAGTGAAATTTATTTGCCTTTAATTCGCTTGT
TGCAATTACATATTGATAGCCATCGCGAAAAAAATATTATTTTAGAAAAATTTCTTTCACATCAAGATATAAAGTCACCT
TTTATTATTGGTATAGCAGGAAGTGTTGCAGTAGGGAAAAGTACAACAGCAAGAATCATTCAGACTCTGCTCAAACAGTT
ATTACCACACTTAGATACTCAACTGGTGACAACAGATGGTTTTCTTTATCCTAATGAAGTTCTAAAAGCTAAGAACATCA
TGCATAAAAAAGGCTTTCCAGAGTCTTATGACACCCACTCTTTGGTTTCTTTTGTTTCTGATGTAAAGTCGGGGAAAAAA
TCGGTATCGGCACCTTTATATTCACACCTAACTTATAACGTAACCGGTGAACGAAAAGTTGTTGAATCGCCTGACATATT
AATCATTGAGGGTTTAAATGTACTTCAAAATGGTAACGATTATCCTGACGATCAGCATCACCGTTTTGTTTCAGACTTTC
TTAACTTCTCAATATATGTTGACGCATCACCAGAACAACTTAAAGAATGGTATGTTGAGCGTTTTTTAAAATTACGAGAA
AGTGCCTTTAAAGAACATGGATCTTATTTTTCGCACTACACAGAATTATCTACCGCAGACTCAATTAAAAAAGCTCAACA
TATTTGGGATACAATTAATGGCCTCAACCTTGAGGAAAACATCTTACCAACAAAGAATCGAGCTAGTCTTATTCTTTCAA
AAGGTGAAAACCATTCAATTAACCAAGTAGCAATAAGAAAGTAG

Upstream 100 bases:

>100_bases
CTATCTCATCAAATCAATAACCAAAAAGTAATAAGACCGCTTTTTTCTTAAAGAGGCTTATTGTATTGTTCAACATTCAT
TAATCCACTAGGTAAGTCAT

Downstream 100 bases:

>100_bases
CAATAAGAAAGTAGCTATTATTTCTTTATAGATATTTCACCACCATTATAAGCCGTTAGGCCATCAGCATTGATAAGTAG
CAGTGCACCTTGAGCATCAA

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MNSYLTFTREHWAELRKSTPMTLTEKELTSLRGINENISIDEVSEIYLPLIRLLQLHIDSHREKNIILEKFLSHQDIKSP
FIIGIAGSVAVGKSTTARIIQTLLKQLLPHLDTQLVTTDGFLYPNEVLKAKNIMHKKGFPESYDTHSLVSFVSDVKSGKK
SVSAPLYSHLTYNVTGERKVVESPDILIIEGLNVLQNGNDYPDDQHHRFVSDFLNFSIYVDASPEQLKEWYVERFLKLRE
SAFKEHGSYFSHYTELSTADSIKKAQHIWDTINGLNLEENILPTKNRASLILSKGENHSINQVAIRK

Sequences:

>Translated_307_residues
MNSYLTFTREHWAELRKSTPMTLTEKELTSLRGINENISIDEVSEIYLPLIRLLQLHIDSHREKNIILEKFLSHQDIKSP
FIIGIAGSVAVGKSTTARIIQTLLKQLLPHLDTQLVTTDGFLYPNEVLKAKNIMHKKGFPESYDTHSLVSFVSDVKSGKK
SVSAPLYSHLTYNVTGERKVVESPDILIIEGLNVLQNGNDYPDDQHHRFVSDFLNFSIYVDASPEQLKEWYVERFLKLRE
SAFKEHGSYFSHYTELSTADSIKKAQHIWDTINGLNLEENILPTKNRASLILSKGENHSINQVAIRK
>Mature_307_residues
MNSYLTFTREHWAELRKSTPMTLTEKELTSLRGINENISIDEVSEIYLPLIRLLQLHIDSHREKNIILEKFLSHQDIKSP
FIIGIAGSVAVGKSTTARIIQTLLKQLLPHLDTQLVTTDGFLYPNEVLKAKNIMHKKGFPESYDTHSLVSFVSDVKSGKK
SVSAPLYSHLTYNVTGERKVVESPDILIIEGLNVLQNGNDYPDDQHHRFVSDFLNFSIYVDASPEQLKEWYVERFLKLRE
SAFKEHGSYFSHYTELSTADSIKKAQHIWDTINGLNLEENILPTKNRASLILSKGENHSINQVAIRK

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=309, Percent_Identity=57.2815533980583, Blast_Score=367, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 35088; Mature: 35088

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSYLTFTREHWAELRKSTPMTLTEKELTSLRGINENISIDEVSEIYLPLIRLLQLHIDS
CCCCEEHHHHHHHHHHHCCCCEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC
HREKNIILEKFLSHQDIKSPFIIGIAGSVAVGKSTTARIIQTLLKQLLPHLDTQLVTTDG
CCHHHHHHHHHHHHHCCCCCEEEEECCCEECCCCHHHHHHHHHHHHHHHHCCCEEEECCC
FLYPNEVLKAKNIMHKKGFPESYDTHSLVSFVSDVKSGKKSVSAPLYSHLTYNVTGERKV
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCEEE
VESPDILIIEGLNVLQNGNDYPDDQHHRFVSDFLNFSIYVDASPEQLKEWYVERFLKLRE
ECCCCEEEEECCHHHCCCCCCCCHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHH
SAFKEHGSYFSHYTELSTADSIKKAQHIWDTINGLNLEENILPTKNRASLILSKGENHSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCC
NQVAIRK
CEEEECC
>Mature Secondary Structure
MNSYLTFTREHWAELRKSTPMTLTEKELTSLRGINENISIDEVSEIYLPLIRLLQLHIDS
CCCCEEHHHHHHHHHHHCCCCEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHC
HREKNIILEKFLSHQDIKSPFIIGIAGSVAVGKSTTARIIQTLLKQLLPHLDTQLVTTDG
CCHHHHHHHHHHHHHCCCCCEEEEECCCEECCCCHHHHHHHHHHHHHHHHCCCEEEECCC
FLYPNEVLKAKNIMHKKGFPESYDTHSLVSFVSDVKSGKKSVSAPLYSHLTYNVTGERKV
CCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCEEEEECCCEEE
VESPDILIIEGLNVLQNGNDYPDDQHHRFVSDFLNFSIYVDASPEQLKEWYVERFLKLRE
ECCCCEEEEECCHHHCCCCCCCCHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHHHHHHH
SAFKEHGSYFSHYTELSTADSIKKAQHIWDTINGLNLEENILPTKNRASLILSKGENHSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCC
NQVAIRK
CEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]