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The map label for this gene is nudC [H]

Identifier: 59713010

GI number: 59713010

Start: 2690096

End: 2690854

Strand: Reverse

Name: nudC [H]

Synonym: VF_2403

Alternate gene names: 59713010

Gene position: 2690854-2690096 (Counterclockwise)

Preceding gene: 59713012

Following gene: 59713009

Centisome position: 92.87

GC content: 37.02

Gene sequence:

>759_bases
ATGTTAAACCAACATACAAAAGCATATTGGTGCGTAGTAAATGATTCAAACATTTGGCTAAAAGACAAAGCGCTTCCAAA
TGGTAGTGCAATAGAGTTTAACTTACCTTTCGAGCAGGCTATATGTATTGGTTATCATAATGAAAAACCAGTTATGTGGT
TAAATGATGAGTTGGTAAATCAGGAACTTATTTATACAAATCTCCGAGAATTATTAGAATATCCACAAACTGATTTTTTA
TTATTTAGTAAAGCCATTCAGTATGGATTTATGGCAAGAGAGTTTCGTTTTTGCCCGCAATGTGGTGGCCGAACTCAGCT
CAACCATAATCAAATTGCGATGCAATGTAATGATTGTCGCAAACTCCATTATCCTAGAATATTCCCTTCAATTATTGTTG
CCGTTCGCCGTGATGATAAGGTACTACTTGCTCAACATCAAAGGCATAAAGGTGGTTTGTTTACTGTCTTAGCTGGGTTT
GTTGAGGTTGGTGAAACTTTGGAGATGGCTGTTTCTCGTGAGGTGCTTGAGGAAACGGGCATAAAAATAAAAAATATTCG
TTATGTTGGCAGTCAGCCTTGGGCTTTTCCATCAAGCTTAATGATGGGATATATGGCGGACTATGAGTCTGGTGAGATAA
AAGTAGATAAAAATGAGCTCATTAAAGCGGGTTGGTATGATAAAAATGTACTACCGGAATTAGCGCCAAAAGGGACAATA
GCAAGAGCGTTAATTGAAGCAACATTGAATGAAATTTAA

Upstream 100 bases:

>100_bases
TCTGAGTGTGGTTTCAGTGAAAATTGTTTGGGTATATACTCATTACTATTCTTTAAGATTGCCAGTAAACATTGATGGCT
GCAAGAGGGTTGTGATAAAG

Downstream 100 bases:

>100_bases
AAGAAAAAAACACCCAAACAGATGAATGGGTGTAAGTAAGGTGTTGTTATGATTTCCAATTTTAACAATTGTTAATTGGA
TGTTGTTATTTTCACTAGCA

Product: NADH pyrophosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MLNQHTKAYWCVVNDSNIWLKDKALPNGSAIEFNLPFEQAICIGYHNEKPVMWLNDELVNQELIYTNLRELLEYPQTDFL
LFSKAIQYGFMAREFRFCPQCGGRTQLNHNQIAMQCNDCRKLHYPRIFPSIIVAVRRDDKVLLAQHQRHKGGLFTVLAGF
VEVGETLEMAVSREVLEETGIKIKNIRYVGSQPWAFPSSLMMGYMADYESGEIKVDKNELIKAGWYDKNVLPELAPKGTI
ARALIEATLNEI

Sequences:

>Translated_252_residues
MLNQHTKAYWCVVNDSNIWLKDKALPNGSAIEFNLPFEQAICIGYHNEKPVMWLNDELVNQELIYTNLRELLEYPQTDFL
LFSKAIQYGFMAREFRFCPQCGGRTQLNHNQIAMQCNDCRKLHYPRIFPSIIVAVRRDDKVLLAQHQRHKGGLFTVLAGF
VEVGETLEMAVSREVLEETGIKIKNIRYVGSQPWAFPSSLMMGYMADYESGEIKVDKNELIKAGWYDKNVLPELAPKGTI
ARALIEATLNEI
>Mature_252_residues
MLNQHTKAYWCVVNDSNIWLKDKALPNGSAIEFNLPFEQAICIGYHNEKPVMWLNDELVNQELIYTNLRELLEYPQTDFL
LFSKAIQYGFMAREFRFCPQCGGRTQLNHNQIAMQCNDCRKLHYPRIFPSIIVAVRRDDKVLLAQHQRHKGGLFTVLAGF
VEVGETLEMAVSREVLEETGIKIKNIRYVGSQPWAFPSSLMMGYMADYESGEIKVDKNELIKAGWYDKNVLPELAPKGTI
ARALIEATLNEI

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI13899267, Length=154, Percent_Identity=43.5064935064935, Blast_Score=127, Evalue=7e-30,
Organism=Homo sapiens, GI50593112, Length=147, Percent_Identity=34.6938775510204, Blast_Score=90, Evalue=2e-18,
Organism=Escherichia coli, GI48994995, Length=242, Percent_Identity=46.2809917355372, Blast_Score=228, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI71986510, Length=157, Percent_Identity=32.484076433121, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI212645999, Length=157, Percent_Identity=32.484076433121, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321371, Length=172, Percent_Identity=34.8837209302326, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376 [H]

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase [H]

EC number: =3.6.1.22 [H]

Molecular weight: Translated: 28948; Mature: 28948

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNQHTKAYWCVVNDSNIWLKDKALPNGSAIEFNLPFEQAICIGYHNEKPVMWLNDELVN
CCCCCCEEEEEEEECCCEEEEECCCCCCCEEEEECCHHHEEEEEEECCCCEEEECHHHHC
QELIYTNLRELLEYPQTDFLLFSKAIQYGFMAREFRFCPQCGGRTQLNHNQIAMQCNDCR
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHH
KLHYPRIFPSIIVAVRRDDKVLLAQHQRHKGGLFTVLAGFVEVGETLEMAVSREVLEETG
HCCCCHHHHHHEEEECCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IKIKNIRYVGSQPWAFPSSLMMGYMADYESGEIKVDKNELIKAGWYDKNVLPELAPKGTI
CEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEECHHHHEECCCCCCCCCCCCCCCHHH
ARALIEATLNEI
HHHHHHHHHHCC
>Mature Secondary Structure
MLNQHTKAYWCVVNDSNIWLKDKALPNGSAIEFNLPFEQAICIGYHNEKPVMWLNDELVN
CCCCCCEEEEEEEECCCEEEEECCCCCCCEEEEECCHHHEEEEEEECCCCEEEECHHHHC
QELIYTNLRELLEYPQTDFLLFSKAIQYGFMAREFRFCPQCGGRTQLNHNQIAMQCNDCR
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHH
KLHYPRIFPSIIVAVRRDDKVLLAQHQRHKGGLFTVLAGFVEVGETLEMAVSREVLEETG
HCCCCHHHHHHEEEECCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IKIKNIRYVGSQPWAFPSSLMMGYMADYESGEIKVDKNELIKAGWYDKNVLPELAPKGTI
CEEEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEECHHHHEECCCCCCCCCCCCCCCHHH
ARALIEATLNEI
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA