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The map label for this gene is uspA [H]

Identifier: 59712962

GI number: 59712962

Start: 2643217

End: 2643642

Strand: Reverse

Name: uspA [H]

Synonym: VF_2355

Alternate gene names: 59712962

Gene position: 2643642-2643217 (Counterclockwise)

Preceding gene: 59712965

Following gene: 172087766

Centisome position: 91.24

GC content: 36.62

Gene sequence:

>426_bases
ATGAAATACAAACATATTCTAGTTGCTCTGGATCTTTCAAAAGAAAGCCATTTATTGATTGATAGAGCAGCCTCATTAGC
CGAACTTGCGGGGGCAAAAGTATCGTTTATTCATATTGATGGGACTCATGGAGAAATTTATCCTGAGTTAATTGATATTC
AGGCTGAACCTGAATTAAAGCCATTAAATGAATCTTCAAATAAGTGGCTTACTGAATTTCAGCAATATACGATATTTCCA
GTTGAACATTTCTGGGTAGGAACTGGCGATTTGAGTAATAAGGTGAGTCTTGCTGTTACAGATACAGACGTCGACCTTAT
TATTTGTGGTCATCACCATGACTTCCTGAGTAAGATTATTTCTTATTCTCGACCATTGATAAACCATTCACCTGTCGATA
TTTTGGTTGTTCCAATCCCTTCGTAA

Upstream 100 bases:

>100_bases
AATAAATTGTCATTTGTTGCGGTTTCGGGATCCCTACGACACTATTTTTCTCATACTAAAACTATGCTTGTTTGGATGAC
AACTCAAAGAGGGTGTGGTG

Downstream 100 bases:

>100_bases
AGACATAAAAAAATGGCAGCTTAATCAGCTGCCATTTTGAGGGATATTATTGCAATTCACCTATTAAAGAATAATACCAC
CGAATGCAAAACCTAGAGCA

Product: universal stress protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MKYKHILVALDLSKESHLLIDRAASLAELAGAKVSFIHIDGTHGEIYPELIDIQAEPELKPLNESSNKWLTEFQQYTIFP
VEHFWVGTGDLSNKVSLAVTDTDVDLIICGHHHDFLSKIISYSRPLINHSPVDILVVPIPS

Sequences:

>Translated_141_residues
MKYKHILVALDLSKESHLLIDRAASLAELAGAKVSFIHIDGTHGEIYPELIDIQAEPELKPLNESSNKWLTEFQQYTIFP
VEHFWVGTGDLSNKVSLAVTDTDVDLIICGHHHDFLSKIISYSRPLINHSPVDILVVPIPS
>Mature_141_residues
MKYKHILVALDLSKESHLLIDRAASLAELAGAKVSFIHIDGTHGEIYPELIDIQAEPELKPLNESSNKWLTEFQQYTIFP
VEHFWVGTGDLSNKVSLAVTDTDVDLIICGHHHDFLSKIISYSRPLINHSPVDILVVPIPS

Specific function: Required for resistance to DNA-damaging agents [H]

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family [H]

Homologues:

Organism=Escherichia coli, GI1789909, Length=139, Percent_Identity=42.4460431654676, Blast_Score=119, Evalue=7e-29,
Organism=Escherichia coli, GI1790358, Length=138, Percent_Identity=31.1594202898551, Blast_Score=80, Evalue=4e-17,
Organism=Escherichia coli, GI1788205, Length=140, Percent_Identity=30, Blast_Score=67, Evalue=6e-13,

Paralogues:

None

Copy number: 1660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 290 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4003 Molecules/Cell In: Growth Phase, G

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014729
- InterPro:   IPR006016 [H]

Pfam domain/function: PF00582 Usp [H]

EC number: NA

Molecular weight: Translated: 15778; Mature: 15778

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYKHILVALDLSKESHLLIDRAASLAELAGAKVSFIHIDGTHGEIYPELIDIQAEPELK
CCCEEEEEEEECCCCCEEEEHHHHHHHHHCCCEEEEEEEECCCCEECCEEEEEECCCCCC
PLNESSNKWLTEFQQYTIFPVEHFWVGTGDLSNKVSLAVTDTDVDLIICGHHHDFLSKII
CCCCCCCHHHHHHHHEEEEEEHHEEEECCCCCCEEEEEEECCCEEEEEECCCHHHHHHHH
SYSRPLINHSPVDILVVPIPS
HHCCCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MKYKHILVALDLSKESHLLIDRAASLAELAGAKVSFIHIDGTHGEIYPELIDIQAEPELK
CCCEEEEEEEECCCCCEEEEHHHHHHHHHCCCEEEEEEEECCCCEECCEEEEEECCCCCC
PLNESSNKWLTEFQQYTIFPVEHFWVGTGDLSNKVSLAVTDTDVDLIICGHHHDFLSKII
CCCCCCCHHHHHHHHEEEEEEHHEEEECCCCCCEEEEEEECCCEEEEEECCCHHHHHHHH
SYSRPLINHSPVDILVVPIPS
HHCCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]