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The map label for this gene is yadR [H]

Identifier: 59712741

GI number: 59712741

Start: 2382628

End: 2382969

Strand: Reverse

Name: yadR [H]

Synonym: VF_2134

Alternate gene names: 59712741

Gene position: 2382969-2382628 (Counterclockwise)

Preceding gene: 59712756

Following gene: 59712740

Centisome position: 82.24

GC content: 39.47

Gene sequence:

>342_bases
ATGAGTGATGTATCTGTGCCGTTAACGTTTTCTGATGTTGCAGCAGCAAAAGTAAAAACGTTAATTGCAGAAGAAGAAAA
CCCAAATCTAAAACTACGAGTTTATATTACTGGTGGTGGTTGTAGTGGTTTCCAATACGGCTTTACTTTTGATGAAGACG
TAAATGAAGGCGATATGACGATTGAAAATGATGGCGTTACGCTAGTTGTTGATCCGATGAGTCTACAATATTTGATCGGC
GGTAAAGTTGATTATACCGAAGGTTTAGAGGGTTCTCGTTTCTTCATTGATAACCCAAATGCAACGACAACGTGTGGTTG
TGGTGCGTCATTCAGTGTGTAA

Upstream 100 bases:

>100_bases
AGAGAACGCAGAGAAGAGCGATTGAATACTTGAATGAAACAGTCAGGTATTAGATAATTGCCTATAAAATAGAATTGGAA
ACCAATCCTGAGAGGTTTAA

Downstream 100 bases:

>100_bases
ACCCTGAGTATTTAAAGGTAAGTAGAGGAGTTTACTTACCTTTTTTATTATAAAAAAATCATAATTTTGAATAACAGTAA
GTTCAGATGTATTACTGTTA

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 112

Protein sequence:

>113_residues
MSDVSVPLTFSDVAAAKVKTLIAEEENPNLKLRVYITGGGCSGFQYGFTFDEDVNEGDMTIENDGVTLVVDPMSLQYLIG
GKVDYTEGLEGSRFFIDNPNATTTCGCGASFSV

Sequences:

>Translated_113_residues
MSDVSVPLTFSDVAAAKVKTLIAEEENPNLKLRVYITGGGCSGFQYGFTFDEDVNEGDMTIENDGVTLVVDPMSLQYLIG
GKVDYTEGLEGSRFFIDNPNATTTCGCGASFSV
>Mature_112_residues
SDVSVPLTFSDVAAAKVKTLIAEEENPNLKLRVYITGGGCSGFQYGFTFDEDVNEGDMTIENDGVTLVVDPMSLQYLIGG
KVDYTEGLEGSRFFIDNPNATTTCGCGASFSV

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=83, Percent_Identity=44.578313253012, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=30.188679245283, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786351, Length=111, Percent_Identity=79.2792792792793, Blast_Score=190, Evalue=2e-50,
Organism=Escherichia coli, GI1788877, Length=110, Percent_Identity=41.8181818181818, Blast_Score=73, Evalue=4e-15,
Organism=Escherichia coli, GI1787974, Length=107, Percent_Identity=32.7102803738318, Blast_Score=59, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI25146411, Length=113, Percent_Identity=30.0884955752212, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193209025, Length=107, Percent_Identity=31.7757009345794, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=36.1111111111111, Blast_Score=75, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6323001, Length=106, Percent_Identity=36.7924528301887, Blast_Score=75, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=44.578313253012, Blast_Score=73, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24642263, Length=107, Percent_Identity=32.7102803738318, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 12065; Mature: 11933

Theoretical pI: Translated: 3.77; Mature: 3.77

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVSVPLTFSDVAAAKVKTLIAEEENPNLKLRVYITGGGCSGFQYGFTFDEDVNEGDMT
CCCCEEEEEEHHHHHHHEEEEEECCCCCCEEEEEEEECCCCCCEECCEEECCCCCCCCEE
IENDGVTLVVDPMSLQYLIGGKVDYTEGLEGSRFFIDNPNATTTCGCGASFSV
EECCCEEEEECCCEEEEEECCEEECCCCCCCCEEEEECCCCCEEECCCCCCCC
>Mature Secondary Structure 
SDVSVPLTFSDVAAAKVKTLIAEEENPNLKLRVYITGGGCSGFQYGFTFDEDVNEGDMT
CCCEEEEEEHHHHHHHEEEEEECCCCCCEEEEEEEECCCCCCEECCEEECCCCCCCCEE
IENDGVTLVVDPMSLQYLIGGKVDYTEGLEGSRFFIDNPNATTTCGCGASFSV
EECCCEEEEECCCEEEEEECCEEECCCCCCCCEEEEECCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA