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The map label for this gene is secD [H]

Identifier: 59712574

GI number: 59712574

Start: 2198141

End: 2199997

Strand: Reverse

Name: secD [H]

Synonym: VF_1967

Alternate gene names: 59712574

Gene position: 2199997-2198141 (Counterclockwise)

Preceding gene: 59712575

Following gene: 59712573

Centisome position: 75.93

GC content: 41.79

Gene sequence:

>1857_bases
GTGTTAAACCGTTTCCCTTTATGGAAGTATTTGATGGTAGTTTCTGTACTACTAATCTCAGCTCTCTATGCACTTCCAAA
CCTCTATGGTGAAGATCCAGCAGTTCAAATCACGGGTAGCCGTGGTACAGAGGTTCAAGCCTCTACGCTGGATGTTGTCG
CTGAAAATTTAAAGAACAATGACATCGCTTACAAGTCAATTGCATTTGAAAATGGCTCCGTTCTTGTTCGTTTTAACGAT
ACTGATGCTCAAATCAGTGCTCGTGATATTATTAATGAATCTTTAGGTAAAGATTACGTTGTTGCATTAAATCTTGCACC
ATTAACTCCTGATTGGCTAACTTCTATTGGTGCTGCGCCAATGAAATTAGGTCTTGATTTACGTGGTGGTGTTCACTTCT
TAATGGAAGTGGATATGGATGCGGCAATGAGTAAGTTGATTGGTCAACAAGAAGAATCATTCCGTACTGATTTACGTGAA
GCTAAGATCCGTTACCGTGCAATTCGTGACTCAGGTAAAGATTCTGTAGAAGTGGTTCTTCGTAATGAAGAGCAATTAGC
TGAAGCGAAAAAAGTGTTATCTGATGCTCACCGTGATATGACATTTGTTGAATCAGAGTCAAACGGTCAATTTAAGTTAA
TTGCAACGTTTACTGAACAACGCTTACAAGAAATTCGTAATTACGCAGTTGAGCAAAACATCACGATCATTCGTAATCGT
GTTAATGAATTAGGTGTTGCAGAACCATTAGTTCAACGTCAAGGTGCAAGCCGTATTGTTGTTGAGCTACCAGGTGTTCA
AGATACTGCGCGTGCTAAAGAAATTCTAGGTGCAACAGCGACACTTGAGTTCCGTGAAGTTGATGATAAAGCGGATTTGG
CTGCAGCAGCAAGCGGACGAGCACCTGCGGGTAGCGAAATCAAAGAAGATCGTAATGGTCGTCCTGTTGTTCTTAAAAAA
CGCATTATTCTTGGCGGTGCAAGCATTACAGATGCAAGTTCAAGTGCTGATGAATATGGTCGTCCTCAAGTAAACATCTC
ACTAGATAGTGAAGGTGGTAGCAAGATGACTGCGTTCTCTCGTAAAAATATCGGTAAGCTAATGGCAACGGTATTTACAG
AATATAAAGACAGTGGTCGTCGTACACCTGAAGGTCGCGTTATTCTTTCTAAGACGGAAGAAGTGATTAACCAAGCAACG
ATTCAATCGGCTCTTGGTCGTAGTTTCCGTATTACTGGTATCGACTCTCAAGCTGAAGCTCATAACCTAGCACTTCTACT
TCGTGCTGGTGCTCTAATTGCGCCTATCTCGATTGTTGAAGAACGTACGATTGGTCCATCAATGGGTCAGCAGAATATCG
ATATGGGTATTCAGGCGTGTATTTGGGGTATGGTTGCTGTAATGATCTTTACACTGGTTTATTACCGTGGTTTTGGTCTT
GTTGCAAACTTAGCCTTAATGGCAAACTTGGTATTAATCATTGGTGTTATGTCGATGATCCCAGGAGCAACAATGACGCT
TCCAGGTATTGCCGGTATCGTATTAACGGTTGGTATGGCGGTCGATGCTAACGTACTTATTTTCGAGCGTATTCGAGAAG
AGTTGCGTGATGGACGTAATCCACAACAAGCAATTCACCAAGGTTATGCGAATGCCTTTAGTACCATTGCCGATGCGAAC
ATCACAACGCTAATTACAGCGATTATCTTGTTTGCTGTTGGTACTGGCGCAATTAAAGGTTTCGCTGTTACGTTATCTAT
CGGTATTTTAACATCAATGTTTACTGCGATTGTTGGTACTCGTTGTGTGATTAACTTAGTTTACGGCGGTAAGCGCGTAG
ACAAGCTGTCGATCTAA

Upstream 100 bases:

>100_bases
ATTTTGTTTCAGCTGTTCTGCCAAAGGGCACTCTGAAATCACTATAAAAATTGTACCCTCTAACTTCGGTTAGGGGGTAT
TTTTCGTTAAGGACATCGCT

Downstream 100 bases:

>100_bases
GGACTCATTATTATGTTTCAATTAATGAAAGCAGAGAAAACGATCGACTTCATGCGTTGGTCTAAAGCTGCCTTCCTTTT
CTCAATGTTGATGATTATTG

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 618; Mature: 618

Protein sequence:

>618_residues
MLNRFPLWKYLMVVSVLLISALYALPNLYGEDPAVQITGSRGTEVQASTLDVVAENLKNNDIAYKSIAFENGSVLVRFND
TDAQISARDIINESLGKDYVVALNLAPLTPDWLTSIGAAPMKLGLDLRGGVHFLMEVDMDAAMSKLIGQQEESFRTDLRE
AKIRYRAIRDSGKDSVEVVLRNEEQLAEAKKVLSDAHRDMTFVESESNGQFKLIATFTEQRLQEIRNYAVEQNITIIRNR
VNELGVAEPLVQRQGASRIVVELPGVQDTARAKEILGATATLEFREVDDKADLAAAASGRAPAGSEIKEDRNGRPVVLKK
RIILGGASITDASSSADEYGRPQVNISLDSEGGSKMTAFSRKNIGKLMATVFTEYKDSGRRTPEGRVILSKTEEVINQAT
IQSALGRSFRITGIDSQAEAHNLALLLRAGALIAPISIVEERTIGPSMGQQNIDMGIQACIWGMVAVMIFTLVYYRGFGL
VANLALMANLVLIIGVMSMIPGATMTLPGIAGIVLTVGMAVDANVLIFERIREELRDGRNPQQAIHQGYANAFSTIADAN
ITTLITAIILFAVGTGAIKGFAVTLSIGILTSMFTAIVGTRCVINLVYGGKRVDKLSI

Sequences:

>Translated_618_residues
MLNRFPLWKYLMVVSVLLISALYALPNLYGEDPAVQITGSRGTEVQASTLDVVAENLKNNDIAYKSIAFENGSVLVRFND
TDAQISARDIINESLGKDYVVALNLAPLTPDWLTSIGAAPMKLGLDLRGGVHFLMEVDMDAAMSKLIGQQEESFRTDLRE
AKIRYRAIRDSGKDSVEVVLRNEEQLAEAKKVLSDAHRDMTFVESESNGQFKLIATFTEQRLQEIRNYAVEQNITIIRNR
VNELGVAEPLVQRQGASRIVVELPGVQDTARAKEILGATATLEFREVDDKADLAAAASGRAPAGSEIKEDRNGRPVVLKK
RIILGGASITDASSSADEYGRPQVNISLDSEGGSKMTAFSRKNIGKLMATVFTEYKDSGRRTPEGRVILSKTEEVINQAT
IQSALGRSFRITGIDSQAEAHNLALLLRAGALIAPISIVEERTIGPSMGQQNIDMGIQACIWGMVAVMIFTLVYYRGFGL
VANLALMANLVLIIGVMSMIPGATMTLPGIAGIVLTVGMAVDANVLIFERIREELRDGRNPQQAIHQGYANAFSTIADAN
ITTLITAIILFAVGTGAIKGFAVTLSIGILTSMFTAIVGTRCVINLVYGGKRVDKLSI
>Mature_618_residues
MLNRFPLWKYLMVVSVLLISALYALPNLYGEDPAVQITGSRGTEVQASTLDVVAENLKNNDIAYKSIAFENGSVLVRFND
TDAQISARDIINESLGKDYVVALNLAPLTPDWLTSIGAAPMKLGLDLRGGVHFLMEVDMDAAMSKLIGQQEESFRTDLRE
AKIRYRAIRDSGKDSVEVVLRNEEQLAEAKKVLSDAHRDMTFVESESNGQFKLIATFTEQRLQEIRNYAVEQNITIIRNR
VNELGVAEPLVQRQGASRIVVELPGVQDTARAKEILGATATLEFREVDDKADLAAAASGRAPAGSEIKEDRNGRPVVLKK
RIILGGASITDASSSADEYGRPQVNISLDSEGGSKMTAFSRKNIGKLMATVFTEYKDSGRRTPEGRVILSKTEEVINQAT
IQSALGRSFRITGIDSQAEAHNLALLLRAGALIAPISIVEERTIGPSMGQQNIDMGIQACIWGMVAVMIFTLVYYRGFGL
VANLALMANLVLIIGVMSMIPGATMTLPGIAGIVLTVGMAVDANVLIFERIREELRDGRNPQQAIHQGYANAFSTIADAN
ITTLITAIILFAVGTGAIKGFAVTLSIGILTSMFTAIVGTRCVINLVYGGKRVDKLSI

Specific function: Involved in protein export [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=618, Percent_Identity=61.6504854368932, Blast_Score=773, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 66968; Mature: 66968

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNRFPLWKYLMVVSVLLISALYALPNLYGEDPAVQITGSRGTEVQASTLDVVAENLKNN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEHHHHHHHHHHCCCC
DIAYKSIAFENGSVLVRFNDTDAQISARDIINESLGKDYVVALNLAPLTPDWLTSIGAAP
CEEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCCCC
MKLGLDLRGGVHFLMEVDMDAAMSKLIGQQEESFRTDLREAKIRYRAIRDSGKDSVEVVL
HHCCCCCCCCEEEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
RNEEQLAEAKKVLSDAHRDMTFVESESNGQFKLIATFTEQRLQEIRNYAVEQNITIIRNR
CCHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHH
VNELGVAEPLVQRQGASRIVVELPGVQDTARAKEILGATATLEFREVDDKADLAAAASGR
HHHCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCHHEEEEEECCCHHHHHHHCCCC
APAGSEIKEDRNGRPVVLKKRIILGGASITDASSSADEYGRPQVNISLDSEGGSKMTAFS
CCCCCCHHHCCCCCCEEEEEEEEECCCCCCCCCCCHHHCCCCEEEEEEECCCCCCEEHHH
RKNIGKLMATVFTEYKDSGRRTPEGRVILSKTEEVINQATIQSALGRSFRITGIDSQAEA
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCEEEEECCCCCCHH
HNLALLLRAGALIAPISIVEERTIGPSMGQQNIDMGIQACIWGMVAVMIFTLVYYRGFGL
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VANLALMANLVLIIGVMSMIPGATMTLPGIAGIVLTVGMAVDANVLIFERIREELRDGRN
HHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
PQQAIHQGYANAFSTIADANITTLITAIILFAVGTGAIKGFAVTLSIGILTSMFTAIVGT
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHEEEEHHHHHHHHHHHHHHHH
RCVINLVYGGKRVDKLSI
HHHEEEHCCCCCCCCCCC
>Mature Secondary Structure
MLNRFPLWKYLMVVSVLLISALYALPNLYGEDPAVQITGSRGTEVQASTLDVVAENLKNN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEHHHHHHHHHHCCCC
DIAYKSIAFENGSVLVRFNDTDAQISARDIINESLGKDYVVALNLAPLTPDWLTSIGAAP
CEEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCCCC
MKLGLDLRGGVHFLMEVDMDAAMSKLIGQQEESFRTDLREAKIRYRAIRDSGKDSVEVVL
HHCCCCCCCCEEEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
RNEEQLAEAKKVLSDAHRDMTFVESESNGQFKLIATFTEQRLQEIRNYAVEQNITIIRNR
CCHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHH
VNELGVAEPLVQRQGASRIVVELPGVQDTARAKEILGATATLEFREVDDKADLAAAASGR
HHHCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCHHEEEEEECCCHHHHHHHCCCC
APAGSEIKEDRNGRPVVLKKRIILGGASITDASSSADEYGRPQVNISLDSEGGSKMTAFS
CCCCCCHHHCCCCCCEEEEEEEEECCCCCCCCCCCHHHCCCCEEEEEEECCCCCCEEHHH
RKNIGKLMATVFTEYKDSGRRTPEGRVILSKTEEVINQATIQSALGRSFRITGIDSQAEA
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCEEEEECCCCCCHH
HNLALLLRAGALIAPISIVEERTIGPSMGQQNIDMGIQACIWGMVAVMIFTLVYYRGFGL
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VANLALMANLVLIIGVMSMIPGATMTLPGIAGIVLTVGMAVDANVLIFERIREELRDGRN
HHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
PQQAIHQGYANAFSTIADANITTLITAIILFAVGTGAIKGFAVTLSIGILTSMFTAIVGT
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHEEEEHHHHHHHHHHHHHHHH
RCVINLVYGGKRVDKLSI
HHHEEEHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]