Click here to switch to the map view.

The map label for this gene is rrmA [H]

Identifier: 59712403

GI number: 59712403

Start: 2028636

End: 2029445

Strand: Direct

Name: rrmA [H]

Synonym: VF_1796

Alternate gene names: 59712403

Gene position: 2028636-2029445 (Clockwise)

Preceding gene: 59712401

Following gene: 59712404

Centisome position: 70.01

GC content: 37.41

Gene sequence:

>810_bases
ATGTCTTATCAATGTCCTTTGTGCCAGCATGAGTTGCACTTTTCTAACAATCAATATCGTTGTGAAAACAATCATCAATT
TGATAACGCAAAAGAAGGTTATGTAAACCTAATGCCTGCTCATCACAAACGTTCTAAAAATCCAGGTGATAATAAAGAGA
TGATGCAAGCAAGACGTGCATTTTTAGAAGCTGGGCATTACCAACCAATGCAGCAAAAAGTGGCTGATTTATGTCAACAG
TACGTCAACAGCGATTCAGCCTCTTTACTGGATATTGGTTGTGGTGAAGGTTATTACACCTCCAAAATAGCTGCTCAACT
GGATGGTAAAGAAGCACAGGTCTTTGGTTTAGATATTTCTAAAGTAGCTATTAAGTATGCAGCTAAAAGATATTTAAACT
GTAAATTTAGTGTCGCTTCAAGCCATCGTTTACCTTTTGCAGATCAAAGCTTAGATGGCGTTGTTCGCATCTATGCTCCT
TGCAAGGGTGAAGAATTGCATCGTGCAATTAAAGATGGAGGCTACCTGTTTACAGTAACACCTGCTGGCCATCATCTATA
TGAATTACGTGAAGGCGTTTATGGTGATGTTCGCTTACACGATGAAGAACCAGAAAATATAAATGGATTTGAACTTATTG
AAGAGCAGAAATTAACTTACCATATGCAATTAAATGCTACAGAAGCATTACAGCTGCTTGATATGACGCCATTCGCTTGG
AAAGCAACTTCTGAGTTTAAAATGAACCTAAAAGCGTTAGAAAACTTCAATTGTAAAGCCGATTTCATGATTCGAGTTTA
CAAAAAATAG

Upstream 100 bases:

>100_bases
GAGTAAAAATAAATAGACCATAATTATTTTCACTGATAGTTCTTTTTATTCAATAAACGAACCAGTACACTGCTGCTTCT
CTTTAATTCTAGGTATGGTT

Downstream 100 bases:

>100_bases
CCCTATCTCAAAAATAAGACACCACATAATTCCATGATAAATAAGGATTTATATGGTGTTTTTTATTTCCCTGTCGAAAA
ACCCTCAAGCTTGTTCTCAT

Product: 23S rRNA methyltransferase A

Products: NA

Alternate protein names: 23S rRNA m1G745 methyltransferase; rRNA (guanine-N(1)-)-methyltransferase [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSYQCPLCQHELHFSNNQYRCENNHQFDNAKEGYVNLMPAHHKRSKNPGDNKEMMQARRAFLEAGHYQPMQQKVADLCQQ
YVNSDSASLLDIGCGEGYYTSKIAAQLDGKEAQVFGLDISKVAIKYAAKRYLNCKFSVASSHRLPFADQSLDGVVRIYAP
CKGEELHRAIKDGGYLFTVTPAGHHLYELREGVYGDVRLHDEEPENINGFELIEEQKLTYHMQLNATEALQLLDMTPFAW
KATSEFKMNLKALENFNCKADFMIRVYKK

Sequences:

>Translated_269_residues
MSYQCPLCQHELHFSNNQYRCENNHQFDNAKEGYVNLMPAHHKRSKNPGDNKEMMQARRAFLEAGHYQPMQQKVADLCQQ
YVNSDSASLLDIGCGEGYYTSKIAAQLDGKEAQVFGLDISKVAIKYAAKRYLNCKFSVASSHRLPFADQSLDGVVRIYAP
CKGEELHRAIKDGGYLFTVTPAGHHLYELREGVYGDVRLHDEEPENINGFELIEEQKLTYHMQLNATEALQLLDMTPFAW
KATSEFKMNLKALENFNCKADFMIRVYKK
>Mature_268_residues
SYQCPLCQHELHFSNNQYRCENNHQFDNAKEGYVNLMPAHHKRSKNPGDNKEMMQARRAFLEAGHYQPMQQKVADLCQQY
VNSDSASLLDIGCGEGYYTSKIAAQLDGKEAQVFGLDISKVAIKYAAKRYLNCKFSVASSHRLPFADQSLDGVVRIYAPC
KGEELHRAIKDGGYLFTVTPAGHHLYELREGVYGDVRLHDEEPENINGFELIEEQKLTYHMQLNATEALQLLDMTPFAWK
ATSEFKMNLKALENFNCKADFMIRVYKK

Specific function: Specifically methylates the guanosine in position 745 of 23S rRNA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmA family [H]

Homologues:

Organism=Escherichia coli, GI1788125, Length=269, Percent_Identity=52.4163568773234, Blast_Score=304, Evalue=4e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR016718 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.187 [H]

Molecular weight: Translated: 30790; Mature: 30659

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQCPLCQHELHFSNNQYRCENNHQFDNAKEGYVNLMPAHHKRSKNPGDNKEMMQARRA
CCCCCCCCHHHHCCCCCEEEECCCCCCCCCCCCEEEECCCHHCCCCCCCCCHHHHHHHHH
FLEAGHYQPMQQKVADLCQQYVNSDSASLLDIGCGEGYYTSKIAAQLDGKEAQVFGLDIS
HHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEHHHHHHHCCCCCEEEEECCHH
KVAIKYAAKRYLNCKFSVASSHRLPFADQSLDGVVRIYAPCKGEELHRAIKDGGYLFTVT
HHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCEEEEEC
PAGHHLYELREGVYGDVRLHDEEPENINGFELIEEQKLTYHMQLNATEALQLLDMTPFAW
CCCHHHHHHHCCCCCCEEECCCCCCCCCHHHHHCCCCEEEEEEECHHHHHHHHCCCCCCE
KATSEFKMNLKALENFNCKADFMIRVYKK
ECCHHHHHHHHHHCCCCCCEEEEEEEECC
>Mature Secondary Structure 
SYQCPLCQHELHFSNNQYRCENNHQFDNAKEGYVNLMPAHHKRSKNPGDNKEMMQARRA
CCCCCCCHHHHCCCCCEEEECCCCCCCCCCCCEEEECCCHHCCCCCCCCCHHHHHHHHH
FLEAGHYQPMQQKVADLCQQYVNSDSASLLDIGCGEGYYTSKIAAQLDGKEAQVFGLDIS
HHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEHHHHHHHCCCCCEEEEECCHH
KVAIKYAAKRYLNCKFSVASSHRLPFADQSLDGVVRIYAPCKGEELHRAIKDGGYLFTVT
HHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCEEEEEC
PAGHHLYELREGVYGDVRLHDEEPENINGFELIEEQKLTYHMQLNATEALQLLDMTPFAW
CCCHHHHHHHCCCCCCEEECCCCCCCCCHHHHHCCCCEEEEEEECHHHHHHHHCCCCCCE
KATSEFKMNLKALENFNCKADFMIRVYKK
ECCHHHHHHHHHHCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7984109; 9097040; 9278503; 9440525 [H]