Click here to switch to the map view.

The map label for this gene is sgrR [H]

Identifier: 59712281

GI number: 59712281

Start: 1884550

End: 1886292

Strand: Reverse

Name: sgrR [H]

Synonym: VF_1674

Alternate gene names: 59712281

Gene position: 1886292-1884550 (Counterclockwise)

Preceding gene: 59712282

Following gene: 59712279

Centisome position: 65.1

GC content: 35.74

Gene sequence:

>1743_bases
TTGATTGAAGGTAAACTGGCTGCTTATTATTTTCGCATGGTTGAATTAGGTGTTAGAACGGAAGTTTTAATTACTTTAAA
TGAGGTGGCAGATCTCGTTTTCACGAGTGCAAGACATTGCCGAACTATTTTAAAAGAAATGAGCCAGTTAGGGTGGTTAG
AATGGCATCCAAAGGTTGGTCGAAATCAACGTTCTGTTCTTTATTTAAATTACCACGTCAATGAGTTGAAATCAGAATTA
GCTAAGGCCATGATCTCTAATGGTAAGTATGAAAAAGCATTAGCTTTGATAGATCATGATCATGCTTTATTTGGGGCGTT
ACTTCAAAATACCTCAGGTGTGGTTCGACGTGAAGGAGAACTGCATATTCAGCTTACTTATCCTCGTTCTTTTTCTGCAT
TATTACCACATTGTTCATTAAGAAATAGTGAGCGTTTTCTTTTACGGCAGGTTTATTGCTGTTTAACTGAATGTGATTTT
TCGGGAAAACTGTCTTCTCAATTAGCTCACCATTGGACTTATGATGAACAAGCATATCGATGGTGTTTCTATTTACGACC
ACAATTGTATTTTCATGATGGAAGTATGATTACTGCAGAATGTGTCGCTGAATTATTTCAAAAATTAAAAGAGTTGCCAG
AGTATCAAGATGAATTAGAGCACGTCACCGCTATTTCTGCTCCCAATACACATTGTATTGAGTTTAAGTTAAACCAACCG
GATTTAGGGTTTGCGGGTTTACTTGCTGATGCTCGTTATTCGATTCAACCTGTTTCTCAGTTATCGTCATCAAAAACAAG
TATTGGCTGTGGTTTCTTTCAAGTCGATTCTCTTTCAGATACACGATTACAACTACAGGCTTTTGAGCGATATTATGGTT
GTCGTGCATTAGTTGATAGTGTCACGATATGGAAGGTTGCAATGGATTCATTAGGTAAAATTGCAATGAAGAGTGGACAA
GTTGATTTAGATCAAAAGGTCACTTGTACTCATTATCTCGAAAAGAGCCAAGATAATAAAAAAATGAGGAGTAACGAAGT
AAGAACAAGAATTGAAGATGGATGTTTACTTGCGTTATTTAATCACAGTTCAGGGTTATCATTATTACAACGAAAATATT
TAAGTCAGATTTTATCTCCTAATAAGTTACAAGATGAAGTGATTAAATCAGGGGAAAAAATAGAAGCAGTCCCAGCCTAT
AATCTGCTTCAACATTGGATGAAAACACTTAACTCGCCAACAACAGAACTAGAGTTACCTGAAACATTGTCTATAGCAGT
ATTTGATCATCAAACGTTATTTCGATGTGCTAGTGCAATGATGGAGATATTAAATCAGCTTGGCGTAAAGTGTCAGATTA
ATAGTTATTCTTTCGATGAGTTTTATAGAAAAGCAAAAGAAAAGACGTTGCTTGAAGATGTCATCTTAACGAGTCTAGAC
TTAGATGATAACCGTCCAACATCGATCTTTCGTTGGTTATTATCCAATCCTATTTTGCAGCAAAGTCTTTCATTAGATGC
GAAAGAATGGCTACAAGCAGAGTTAATTAATATTAGGAATATAACTGAATTAACAGACTATTTAGGTAAATTAGAGCCTG
TTTCTTCAAGTCTGATTAGTGATTATAAAATATTACCTCTTTTTCATCATAAGCAGACTTTACGTTTTCAAGATGTACTT
AAAGGTGTTTCTATCACGGGGTGGGGGTGGCCTGCAATTCGAGATGTGTGGTCTGAAGATTAG

Upstream 100 bases:

>100_bases
ATTATTTAGTTCCTATTATTGTGGTTTTTAATTGTAAATTTGCCGTTTGTAGGTGTATTTTATTTAAATGGGGAAGTAAG
AATAAAAAAGAGGTGATGTT

Downstream 100 bases:

>100_bases
TGAGTATAAAAAAGCCTGCAAGTGAGCAGGCTTTTGAATTTTTATAACAAGAACAATTTATTGTTTGTAAGTGTGTAGGA
AGCGCTCTAGGCGACCAATC

Product: oligopeptide-binding protein OppA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MIEGKLAAYYFRMVELGVRTEVLITLNEVADLVFTSARHCRTILKEMSQLGWLEWHPKVGRNQRSVLYLNYHVNELKSEL
AKAMISNGKYEKALALIDHDHALFGALLQNTSGVVRREGELHIQLTYPRSFSALLPHCSLRNSERFLLRQVYCCLTECDF
SGKLSSQLAHHWTYDEQAYRWCFYLRPQLYFHDGSMITAECVAELFQKLKELPEYQDELEHVTAISAPNTHCIEFKLNQP
DLGFAGLLADARYSIQPVSQLSSSKTSIGCGFFQVDSLSDTRLQLQAFERYYGCRALVDSVTIWKVAMDSLGKIAMKSGQ
VDLDQKVTCTHYLEKSQDNKKMRSNEVRTRIEDGCLLALFNHSSGLSLLQRKYLSQILSPNKLQDEVIKSGEKIEAVPAY
NLLQHWMKTLNSPTTELELPETLSIAVFDHQTLFRCASAMMEILNQLGVKCQINSYSFDEFYRKAKEKTLLEDVILTSLD
LDDNRPTSIFRWLLSNPILQQSLSLDAKEWLQAELINIRNITELTDYLGKLEPVSSSLISDYKILPLFHHKQTLRFQDVL
KGVSITGWGWPAIRDVWSED

Sequences:

>Translated_580_residues
MIEGKLAAYYFRMVELGVRTEVLITLNEVADLVFTSARHCRTILKEMSQLGWLEWHPKVGRNQRSVLYLNYHVNELKSEL
AKAMISNGKYEKALALIDHDHALFGALLQNTSGVVRREGELHIQLTYPRSFSALLPHCSLRNSERFLLRQVYCCLTECDF
SGKLSSQLAHHWTYDEQAYRWCFYLRPQLYFHDGSMITAECVAELFQKLKELPEYQDELEHVTAISAPNTHCIEFKLNQP
DLGFAGLLADARYSIQPVSQLSSSKTSIGCGFFQVDSLSDTRLQLQAFERYYGCRALVDSVTIWKVAMDSLGKIAMKSGQ
VDLDQKVTCTHYLEKSQDNKKMRSNEVRTRIEDGCLLALFNHSSGLSLLQRKYLSQILSPNKLQDEVIKSGEKIEAVPAY
NLLQHWMKTLNSPTTELELPETLSIAVFDHQTLFRCASAMMEILNQLGVKCQINSYSFDEFYRKAKEKTLLEDVILTSLD
LDDNRPTSIFRWLLSNPILQQSLSLDAKEWLQAELINIRNITELTDYLGKLEPVSSSLISDYKILPLFHHKQTLRFQDVL
KGVSITGWGWPAIRDVWSED
>Mature_580_residues
MIEGKLAAYYFRMVELGVRTEVLITLNEVADLVFTSARHCRTILKEMSQLGWLEWHPKVGRNQRSVLYLNYHVNELKSEL
AKAMISNGKYEKALALIDHDHALFGALLQNTSGVVRREGELHIQLTYPRSFSALLPHCSLRNSERFLLRQVYCCLTECDF
SGKLSSQLAHHWTYDEQAYRWCFYLRPQLYFHDGSMITAECVAELFQKLKELPEYQDELEHVTAISAPNTHCIEFKLNQP
DLGFAGLLADARYSIQPVSQLSSSKTSIGCGFFQVDSLSDTRLQLQAFERYYGCRALVDSVTIWKVAMDSLGKIAMKSGQ
VDLDQKVTCTHYLEKSQDNKKMRSNEVRTRIEDGCLLALFNHSSGLSLLQRKYLSQILSPNKLQDEVIKSGEKIEAVPAY
NLLQHWMKTLNSPTTELELPETLSIAVFDHQTLFRCASAMMEILNQLGVKCQINSYSFDEFYRKAKEKTLLEDVILTSLD
LDDNRPTSIFRWLLSNPILQQSLSLDAKEWLQAELINIRNITELTDYLGKLEPVSSSLISDYKILPLFHHKQTLRFQDVL
KGVSITGWGWPAIRDVWSED

Specific function: Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding

COG id: COG4533

COG function: function code R; ABC-type uncharacterized transport system, periplasmic component

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786256, Length=569, Percent_Identity=27.2407732864675, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1786650, Length=576, Percent_Identity=23.7847222222222, Blast_Score=140, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 66536; Mature: 66536

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEGKLAAYYFRMVELGVRTEVLITLNEVADLVFTSARHCRTILKEMSQLGWLEWHPKVG
CCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
RNQRSVLYLNYHVNELKSELAKAMISNGKYEKALALIDHDHALFGALLQNTSGVVRREGE
CCCCEEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCEEECCE
LHIQLTYPRSFSALLPHCSLRNSERFLLRQVYCCLTECDFSGKLSSQLAHHWTYDEQAYR
EEEEEECCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHE
WCFYLRPQLYFHDGSMITAECVAELFQKLKELPEYQDELEHVTAISAPNTHCIEFKLNQP
EEEEECCEEEEECCCEEHHHHHHHHHHHHHHCCCHHHHHHHHEEECCCCCEEEEEEECCC
DLGFAGLLADARYSIQPVSQLSSSKTSIGCGFFQVDSLSDTRLQLQAFERYYGCRALVDS
CCCHHHHHHCCCCCCCHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
VTIWKVAMDSLGKIAMKSGQVDLDQKVTCTHYLEKSQDNKKMRSNEVRTRIEDGCLLALF
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEE
NHSSGLSLLQRKYLSQILSPNKLQDEVIKSGEKIEAVPAYNLLQHWMKTLNSPTTELELP
ECCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEECHHHHHHHHHHHHHCCCCCEECCC
ETLSIAVFDHQTLFRCASAMMEILNQLGVKCQINSYSFDEFYRKAKEKTLLEDVILTSLD
CCEEEEEECHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
LDDNRPTSIFRWLLSNPILQQSLSLDAKEWLQAELINIRNITELTDYLGKLEPVSSSLIS
CCCCCHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
DYKILPLFHHKQTLRFQDVLKGVSITGWGWPAIRDVWSED
CCEEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MIEGKLAAYYFRMVELGVRTEVLITLNEVADLVFTSARHCRTILKEMSQLGWLEWHPKVG
CCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
RNQRSVLYLNYHVNELKSELAKAMISNGKYEKALALIDHDHALFGALLQNTSGVVRREGE
CCCCEEEEEEECHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCEEECCE
LHIQLTYPRSFSALLPHCSLRNSERFLLRQVYCCLTECDFSGKLSSQLAHHWTYDEQAYR
EEEEEECCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHE
WCFYLRPQLYFHDGSMITAECVAELFQKLKELPEYQDELEHVTAISAPNTHCIEFKLNQP
EEEEECCEEEEECCCEEHHHHHHHHHHHHHHCCCHHHHHHHHEEECCCCCEEEEEEECCC
DLGFAGLLADARYSIQPVSQLSSSKTSIGCGFFQVDSLSDTRLQLQAFERYYGCRALVDS
CCCHHHHHHCCCCCCCHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
VTIWKVAMDSLGKIAMKSGQVDLDQKVTCTHYLEKSQDNKKMRSNEVRTRIEDGCLLALF
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEE
NHSSGLSLLQRKYLSQILSPNKLQDEVIKSGEKIEAVPAYNLLQHWMKTLNSPTTELELP
ECCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEECHHHHHHHHHHHHHCCCCCEECCC
ETLSIAVFDHQTLFRCASAMMEILNQLGVKCQINSYSFDEFYRKAKEKTLLEDVILTSLD
CCEEEEEECHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
LDDNRPTSIFRWLLSNPILQQSLSLDAKEWLQAELINIRNITELTDYLGKLEPVSSSLIS
CCCCCHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
DYKILPLFHHKQTLRFQDVLKGVSITGWGWPAIRDVWSED
CCEEEEEHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]