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The map label for this gene is lplT [H]

Identifier: 59712272

GI number: 59712272

Start: 1873906

End: 1875774

Strand: Direct

Name: lplT [H]

Synonym: VF_1665

Alternate gene names: 59712272

Gene position: 1873906-1875774 (Clockwise)

Preceding gene: 59712271

Following gene: 59712280

Centisome position: 64.67

GC content: 39.22

Gene sequence:

>1869_bases
ATGGCAAAGCAAGCCAAACTACTCACACAGCGTCGATTCCTTCCCTACTTTCTCACTCAATCTCTAGGGGCTTTTAACGA
CAATATTTTTAAAAACACCCTATTATTGTTTGTTGCTTTTGCCAGTGTCGATTCTCTACCTATATCGTCTAATTTATTCA
TTAATTTGGCCGCAGGGTTATTCATTCTTCCTTTTTTTCTTTTTTCTGCTTTTGCTGGCGTACTGGCTGACAAGTATGAG
AAATCGGCTTTTATACGCAAAGTTAAACTCGCTGAAATCATTATCATGCTCTTTGGGGCTATTGCCTTTGTTTTAAAAGA
CTTCACGCTATTACTTATTTTATTGTTTTTAATGGGCACTCAATCCGCTTTTTTTGGTCCAGTAAAATACGCTTTACTCC
CTCAGCAATTAAAAGAAGATGAGTTAGTTTCTGGTAATGCATTAGTTGAAACAGGTACTTTCTTAGCCATTCTATTTGGA
ACCATTGGCGCTGGCATTATTGCTTCTCAAGAGAATGCACAATACATTGCCGCTGGTGCAGTGCTTCTTTTCGCAGTACT
TGGCTATTTATCTAGTCGTTTCATCCCTTATGCAAAAGCCATTGACCCAACACTTTCATTTCGCTGGCGACCAATTCAGC
AAACACGAAATACTATTTCAATCGCCCAAAAAGACAGCTCTGTATTTTTAGCGATTATGGGGATCAGTTGGTTTTGGTTT
TTAGGTGCAAGTTACTTAACTCAGTTTCCTAATTACACTCACCATTTTTTAAACGATAATGCAATTACTGTTAGTGTACT
GCTGGCGTTGTTCTCAGTTGGCATTGCAGTAGGTTCATTAGCCTGTGATGTATTATCTAAACACCGTGTTGAACTAGGCA
TTATTCCTCTTGGCAGCCTTGGTATTACTATTTTTGGTTTCAATCTTTTTTTAGCGACGCCGGCAAATCCAATACATACC
TCTGATTTTTTTGAAATCTTAACGCATCCAGATCTTTTCTCTGTTTTTGTTAATCTCTTTTTTCTAGGGGTTTCTGGAGG
AATATTTATCGTTCCTTTATACACGTTAATCCAAAAACGACCTCAAGCAAAACATCGATCTCAGATCATCGCGGCCAATA
ATATTTATAACGCCATCTTTATGGTAACAAGTGCTATTCTTGGGATTATTTGCTTATCTGTCATAGAGTTAAGTATTCCT
CAATTTTTCCTTCTTCTTGCGATATTAAATGGGATTGTCACCCTCTTTCTGTTTTTCCGTGTGCCTATTTTTATTATTCG
CTTTGTTTTATGGGTCCTCACCCACACGGGATACCGAGTAAGCCATCAACATTTACATCATATTCCAGATGAAGGTGGCG
CTTTGTTAGTATGTAATCACATCACTTACATGGATGCCTTTATTATCAGTGGTGCATGCCCTCGTCCTATTCGATTCGTG
ATGGAGGAGGAATACGCAGAATTACCTTTAATTAAATACTTTTTCAAATTAACGAAAGTTATTCCAATTAATGCCACTAA
AAGTAGCTCAATTCGACGAGCATTTATGGAGGTTGAGAACGCATTAACAAATGGGGAGATTGTGTTGATTTTTCCAGAAG
GCGTGTTGACTCGTGATGGTGAAATCGGTCCTTTCTTACGAGGTATGGATATCATTTTAAAACGCTCACCGGTGCCAGTC
ATTCCAATGGCGCTGCGAGGCTTATGGGGAAGTTTCTTTAGTCGCCATGGCGGTAAAGCAATATTAAAACGCCCTAGTCG
CTGTTGGTCTAAAGTAGAGGTGGTAGCAGGAGAACCCGTACTACCACAAGATGCGACATCAAAACTGATGCGTGAAAAAG
TAGCTCAATTACGCGGTGATTGGCAGTGA

Upstream 100 bases:

>100_bases
CGCCGATTGATGGTCACAAACTTATTGATAATCTGCTGCTAAACTACATCAATCAATGGAAGCTTCATTAAGCGATATTC
TTTGGTAAAAAGGATTTTTT

Downstream 100 bases:

>100_bases
ATCAACCCACTCTTTAACCAATTTACGTGAAATTTTAATGCCAGAAATAAGCAAATGTTCCGGCATGATTTCATAACTTA
TCGGTTGCTCAAATTTAGCC

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 622; Mature: 621

Protein sequence:

>622_residues
MAKQAKLLTQRRFLPYFLTQSLGAFNDNIFKNTLLLFVAFASVDSLPISSNLFINLAAGLFILPFFLFSAFAGVLADKYE
KSAFIRKVKLAEIIIMLFGAIAFVLKDFTLLLILLFLMGTQSAFFGPVKYALLPQQLKEDELVSGNALVETGTFLAILFG
TIGAGIIASQENAQYIAAGAVLLFAVLGYLSSRFIPYAKAIDPTLSFRWRPIQQTRNTISIAQKDSSVFLAIMGISWFWF
LGASYLTQFPNYTHHFLNDNAITVSVLLALFSVGIAVGSLACDVLSKHRVELGIIPLGSLGITIFGFNLFLATPANPIHT
SDFFEILTHPDLFSVFVNLFFLGVSGGIFIVPLYTLIQKRPQAKHRSQIIAANNIYNAIFMVTSAILGIICLSVIELSIP
QFFLLLAILNGIVTLFLFFRVPIFIIRFVLWVLTHTGYRVSHQHLHHIPDEGGALLVCNHITYMDAFIISGACPRPIRFV
MEEEYAELPLIKYFFKLTKVIPINATKSSSIRRAFMEVENALTNGEIVLIFPEGVLTRDGEIGPFLRGMDIILKRSPVPV
IPMALRGLWGSFFSRHGGKAILKRPSRCWSKVEVVAGEPVLPQDATSKLMREKVAQLRGDWQ

Sequences:

>Translated_622_residues
MAKQAKLLTQRRFLPYFLTQSLGAFNDNIFKNTLLLFVAFASVDSLPISSNLFINLAAGLFILPFFLFSAFAGVLADKYE
KSAFIRKVKLAEIIIMLFGAIAFVLKDFTLLLILLFLMGTQSAFFGPVKYALLPQQLKEDELVSGNALVETGTFLAILFG
TIGAGIIASQENAQYIAAGAVLLFAVLGYLSSRFIPYAKAIDPTLSFRWRPIQQTRNTISIAQKDSSVFLAIMGISWFWF
LGASYLTQFPNYTHHFLNDNAITVSVLLALFSVGIAVGSLACDVLSKHRVELGIIPLGSLGITIFGFNLFLATPANPIHT
SDFFEILTHPDLFSVFVNLFFLGVSGGIFIVPLYTLIQKRPQAKHRSQIIAANNIYNAIFMVTSAILGIICLSVIELSIP
QFFLLLAILNGIVTLFLFFRVPIFIIRFVLWVLTHTGYRVSHQHLHHIPDEGGALLVCNHITYMDAFIISGACPRPIRFV
MEEEYAELPLIKYFFKLTKVIPINATKSSSIRRAFMEVENALTNGEIVLIFPEGVLTRDGEIGPFLRGMDIILKRSPVPV
IPMALRGLWGSFFSRHGGKAILKRPSRCWSKVEVVAGEPVLPQDATSKLMREKVAQLRGDWQ
>Mature_621_residues
AKQAKLLTQRRFLPYFLTQSLGAFNDNIFKNTLLLFVAFASVDSLPISSNLFINLAAGLFILPFFLFSAFAGVLADKYEK
SAFIRKVKLAEIIIMLFGAIAFVLKDFTLLLILLFLMGTQSAFFGPVKYALLPQQLKEDELVSGNALVETGTFLAILFGT
IGAGIIASQENAQYIAAGAVLLFAVLGYLSSRFIPYAKAIDPTLSFRWRPIQQTRNTISIAQKDSSVFLAIMGISWFWFL
GASYLTQFPNYTHHFLNDNAITVSVLLALFSVGIAVGSLACDVLSKHRVELGIIPLGSLGITIFGFNLFLATPANPIHTS
DFFEILTHPDLFSVFVNLFFLGVSGGIFIVPLYTLIQKRPQAKHRSQIIAANNIYNAIFMVTSAILGIICLSVIELSIPQ
FFLLLAILNGIVTLFLFFRVPIFIIRFVLWVLTHTGYRVSHQHLHHIPDEGGALLVCNHITYMDAFIISGACPRPIRFVM
EEEYAELPLIKYFFKLTKVIPINATKSSSIRRAFMEVENALTNGEIVLIFPEGVLTRDGEIGPFLRGMDIILKRSPVPVI
PMALRGLWGSFFSRHGGKAILKRPSRCWSKVEVVAGEPVLPQDATSKLMREKVAQLRGDWQ

Specific function: Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family [H]

Homologues:

Organism=Escherichia coli, GI1789200, Length=357, Percent_Identity=26.890756302521, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: 2.3.1.51

Molecular weight: Translated: 69165; Mature: 69034

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQAKLLTQRRFLPYFLTQSLGAFNDNIFKNTLLLFVAFASVDSLPISSNLFINLAAGL
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
FILPFFLFSAFAGVLADKYEKSAFIRKVKLAEIIIMLFGAIAFVLKDFTLLLILLFLMGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QSAFFGPVKYALLPQQLKEDELVSGNALVETGTFLAILFGTIGAGIIASQENAQYIAAGA
CCHHHCCHHHHHCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHH
VLLFAVLGYLSSRFIPYAKAIDPTLSFRWRPIQQTRNTISIAQKDSSVFLAIMGISWFWF
HHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEHHHHCCHHHHEECCCCEEEHHHHHHHHHH
LGASYLTQFPNYTHHFLNDNAITVSVLLALFSVGIAVGSLACDVLSKHRVELGIIPLGSL
HHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
GITIFGFNLFLATPANPIHTSDFFEILTHPDLFSVFVNLFFLGVSGGIFIVPLYTLIQKR
CEEEEEEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
PQAKHRSQIIAANNIYNAIFMVTSAILGIICLSVIELSIPQFFLLLAILNGIVTLFLFFR
CCHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPIFIIRFVLWVLTHTGYRVSHQHLHHIPDEGGALLVCNHITYMDAFIISGACPRPIRFV
HHHHHHHHHHHHHHCCCCEECHHHHHCCCCCCCEEEEECHHHHHHHHHHCCCCCCHHHHH
MEEEYAELPLIKYFFKLTKVIPINATKSSSIRRAFMEVENALTNGEIVLIFPEGVLTRDG
HHHHHHCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEECCC
EIGPFLRGMDIILKRSPVPVIPMALRGLWGSFFSRHGGKAILKRPSRCWSKVEVVAGEPV
CCCCHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHEEEEECCCC
LPQDATSKLMREKVAQLRGDWQ
CCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AKQAKLLTQRRFLPYFLTQSLGAFNDNIFKNTLLLFVAFASVDSLPISSNLFINLAAGL
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
FILPFFLFSAFAGVLADKYEKSAFIRKVKLAEIIIMLFGAIAFVLKDFTLLLILLFLMGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QSAFFGPVKYALLPQQLKEDELVSGNALVETGTFLAILFGTIGAGIIASQENAQYIAAGA
CCHHHCCHHHHHCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHH
VLLFAVLGYLSSRFIPYAKAIDPTLSFRWRPIQQTRNTISIAQKDSSVFLAIMGISWFWF
HHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEHHHHCCHHHHEECCCCEEEHHHHHHHHHH
LGASYLTQFPNYTHHFLNDNAITVSVLLALFSVGIAVGSLACDVLSKHRVELGIIPLGSL
HHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
GITIFGFNLFLATPANPIHTSDFFEILTHPDLFSVFVNLFFLGVSGGIFIVPLYTLIQKR
CEEEEEEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
PQAKHRSQIIAANNIYNAIFMVTSAILGIICLSVIELSIPQFFLLLAILNGIVTLFLFFR
CCHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPIFIIRFVLWVLTHTGYRVSHQHLHHIPDEGGALLVCNHITYMDAFIISGACPRPIRFV
HHHHHHHHHHHHHHCCCCEECHHHHHCCCCCCCEEEEECHHHHHHHHHHCCCCCCHHHHH
MEEEYAELPLIKYFFKLTKVIPINATKSSSIRRAFMEVENALTNGEIVLIFPEGVLTRDG
HHHHHHCCHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEECCC
EIGPFLRGMDIILKRSPVPVIPMALRGLWGSFFSRHGGKAILKRPSRCWSKVEVVAGEPV
CCCCHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHEEEEECCCC
LPQDATSKLMREKVAQLRGDWQ
CCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA