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The map label for this gene is mtnN [H]

Identifier: 59712260

GI number: 59712260

Start: 1863909

End: 1864724

Strand: Reverse

Name: mtnN [H]

Synonym: VF_1653

Alternate gene names: 59712260

Gene position: 1864724-1863909 (Counterclockwise)

Preceding gene: 59712261

Following gene: 59712255

Centisome position: 64.36

GC content: 38.6

Gene sequence:

>816_bases
ATGCAGTACCTTCGTTATTTTCTTGCTAGTTTATTTACGCTTGTTTCGTTTTCTTTAGCTGCAGCACCAAAGCCTATTGT
TTTACAAGGCGCCATGGATGTCGAAGTTAACTATATGGTTGAGCAGTTACAAAACAAACAAGAGGTAACTTTTGGCTCTT
GGACGTTTTGGACTGGAACTATTGATGATTATCCAGTCATTGTGTCAAGAACTGAAGTGGGTATTGCTAATGCATCAGCA
TCAACAACTCTAGCTATTGAGAAGTTTTCACCAGGCATGATTATCAACCAAGGGACTTCTGGTGGTCATGATCCAGAGCT
TTACCGTGGTGATATTGTTTTAGCCGTTAAGAGCTTCAATATGGGAGCAAATCGCTCTGAATTCTCTAAAGTAGAAGAAG
GTATTCAACCTGAAAAATGGAAAAACTTCACAGTAACAATGCGATTAAGAGAAGATAATAAGTTTGTTGAGCATGACGCA
TTTTATTCAACTCCAGAGTTAGTGGACTTTGCTTATAAGAATGTAAAGCATCCTGCTCAAGGCAAAGTGGTTAAAGGCGT
GATTGGTACCGCTGATGAATGGAACCGAGAAGTTGCTAGAATTAATTGGCTACACAAAACCTACCAAACTGCGGCAGAAG
AGATGGAGAGCTCATCAGCAGCATTAGTTGCAGAGGCTTATAAAGTACCATTTATCGGTATTCGAATCTTATCGAACACA
GATTTACATAATCAAGATTTTGATCCTGCAACGGCAATTACTAACCAAAAATACGTAATTGATTTTGTTAAACAGTGGAT
TGCGAAGCAAAAATAA

Upstream 100 bases:

>100_bases
CAGAGTGTGAAATAAAATAGCAAACGATTGCTTTTTGTTGGTGTTCCTGTATTATCCGCCAAAATTTTTAATCATAAAAA
TATTAATTAGGGATATATAC

Downstream 100 bases:

>100_bases
TTACCCGCATATATAAAAAGCCCTAGCATCTCTGTTAGGGCTTTAAATATCTTATTGTCACTTCTTTGTATTATTTATCA
TCTATTAAAAAGAAAGATAA

Product: hypothetical protein

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MQYLRYFLASLFTLVSFSLAAAPKPIVLQGAMDVEVNYMVEQLQNKQEVTFGSWTFWTGTIDDYPVIVSRTEVGIANASA
STTLAIEKFSPGMIINQGTSGGHDPELYRGDIVLAVKSFNMGANRSEFSKVEEGIQPEKWKNFTVTMRLREDNKFVEHDA
FYSTPELVDFAYKNVKHPAQGKVVKGVIGTADEWNREVARINWLHKTYQTAAEEMESSSAALVAEAYKVPFIGIRILSNT
DLHNQDFDPATAITNQKYVIDFVKQWIAKQK

Sequences:

>Translated_271_residues
MQYLRYFLASLFTLVSFSLAAAPKPIVLQGAMDVEVNYMVEQLQNKQEVTFGSWTFWTGTIDDYPVIVSRTEVGIANASA
STTLAIEKFSPGMIINQGTSGGHDPELYRGDIVLAVKSFNMGANRSEFSKVEEGIQPEKWKNFTVTMRLREDNKFVEHDA
FYSTPELVDFAYKNVKHPAQGKVVKGVIGTADEWNREVARINWLHKTYQTAAEEMESSSAALVAEAYKVPFIGIRILSNT
DLHNQDFDPATAITNQKYVIDFVKQWIAKQK
>Mature_271_residues
MQYLRYFLASLFTLVSFSLAAAPKPIVLQGAMDVEVNYMVEQLQNKQEVTFGSWTFWTGTIDDYPVIVSRTEVGIANASA
STTLAIEKFSPGMIINQGTSGGHDPELYRGDIVLAVKSFNMGANRSEFSKVEEGIQPEKWKNFTVTMRLREDNKFVEHDA
FYSTPELVDFAYKNVKHPAQGKVVKGVIGTADEWNREVARINWLHKTYQTAAEEMESSSAALVAEAYKVPFIGIRILSNT
DLHNQDFDPATAITNQKYVIDFVKQWIAKQK

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 30522; Mature: 30522

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYLRYFLASLFTLVSFSLAAAPKPIVLQGAMDVEVNYMVEQLQNKQEVTFGSWTFWTGT
CHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCCEEECCEEEEECC
IDDYPVIVSRTEVGIANASASTTLAIEKFSPGMIINQGTSGGHDPELYRGDIVLAVKSFN
CCCCCEEEEECEECEECCCCCEEEEEEECCCCEEEECCCCCCCCCCEEECCEEEEEEECC
MGANRSEFSKVEEGIQPEKWKNFTVTMRLREDNKFVEHDAFYSTPELVDFAYKNVKHPAQ
CCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCCEECCCCCCCCHHHHHHHHHHCCCCCC
GKVVKGVIGTADEWNREVARINWLHKTYQTAAEEMESSSAALVAEAYKVPFIGIRILSNT
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEECC
DLHNQDFDPATAITNQKYVIDFVKQWIAKQK
CCCCCCCCCHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQYLRYFLASLFTLVSFSLAAAPKPIVLQGAMDVEVNYMVEQLQNKQEVTFGSWTFWTGT
CHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCCEEECCEEEEECC
IDDYPVIVSRTEVGIANASASTTLAIEKFSPGMIINQGTSGGHDPELYRGDIVLAVKSFN
CCCCCEEEEECEECEECCCCCEEEEEEECCCCEEEECCCCCCCCCCEEECCEEEEEEECC
MGANRSEFSKVEEGIQPEKWKNFTVTMRLREDNKFVEHDAFYSTPELVDFAYKNVKHPAQ
CCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCCEECCCCCCCCHHHHHHHHHHCCCCCC
GKVVKGVIGTADEWNREVARINWLHKTYQTAAEEMESSSAALVAEAYKVPFIGIRILSNT
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEEECC
DLHNQDFDPATAITNQKYVIDFVKQWIAKQK
CCCCCCCCCHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA