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The map label for this gene is adrA [H]

Identifier: 59712246

GI number: 59712246

Start: 1841751

End: 1843223

Strand: Reverse

Name: adrA [H]

Synonym: VF_1639

Alternate gene names: 59712246

Gene position: 1843223-1841751 (Counterclockwise)

Preceding gene: 59712247

Following gene: 59712243

Centisome position: 63.61

GC content: 32.93

Gene sequence:

>1473_bases
ATGCCGAAATTTAATTTAAAACATATCTTTCTTATACCAACACTATTCCTAGTGTTGATCGTAGGTTTTATTTTAAATAA
CCACATGAACTCCGTACAACGTCAAGTTAATCGAGAGTATGATCGTATTATAAATTCACTTCAACGATCAATTAAAGTAA
TTATTTCTTTGGATTACAATATTTCGCAGCTATATAAGCAAAACCAAGGTAGTTTTTATAATCATAACTTTGAAATTAAG
AAAGATAGTGGCCTTTGTGTTATTCGCCCAAGCGAAAACTTAGATGCGGTAATGGCAGAACAAGACATTTCAGTTGCAGA
AGGACGTCTTGATTATAGTATCGCTGGTAAAAAAGATTTATGTGATCCATCGTCTGAAGTGTATGAAATTGCATCAAAGA
AGGTGAGTCTTGCCCCTGTTATTTCTTTTATCCATGATTATGAAAGCTATCTTCATGGGATCTATTTCATTTCAAAATAT
AATTATATTATCTCTTCACCAAAAGAAATTGCTGAGAATTTATCGCAAAAAACGCTTGATGTTATTTATTCTCGACCATA
CTGGAAAAACAGTATGAAAAACGACAGTGAAAAATACATTACGTTTACACCTCCATATACCGATGCTTTTTTTGACGGGC
TTGAAGTATTAACTTTTTCAACACCTATTTACTATAAAGGTATATTCAAAGGTGTATTGGTCATTGATCTTTCAGTTGAA
AAGCTTTTGCGCTCATCAAATGAAATATCACAGCATATTCAGTTGTTAAACAGTGATGAGTATAAGAGATTTGAACAGTA
TCGTTTTATGCAACCAGTTAATTTAGATTTTACCGACTTTACGTATTTTTTATATTACAAAACATCGATAAAAGAAGAGT
TGAAAGGTTTTCTTGTGCATGATTCTAATTCGTTAATTTTAACGTTAGTAATGTATATCCTCTCTTTACTATCTATGTTC
TATTACCAAAGTCGAGTATCTCAAAAATACTATCGTGATTTGGCTAAACAAGATCCAATGACAGGCTTATATAATCGTCG
TGGTTTTGAGATGAGCTTACAAGATCGTGTTGTGAAAAAGTACGTTGGTTTTGCAATTTATGATATTGATGACTTCAAAC
AAATTAATGATGTGTTTGGACATGATGTGGGTGATGAGGCGATTAAATATGTCGCGAGAATGCTGAATAAGAGTGTGCGT
GATAGTGATATTGTGTCTCGATTTGGCGGTGAAGAATTTGTTATCTGTATTAATGCTGAATCAAGAAATAGCTTAGAAAG
TGTTTGTGAGCGTGTAAGGAAGTCAATTCAGGATTCATCAGGAAAAGTAGTTAAAGGTGGTTTTACTGTTTCTGGTGGCG
TAACGGTAATCGATTCACATCAAGAATTTTCATTTGAACATGTGATTAAGAAAGCCGATGCCTTGCTTTATAAGGCGAAA
CAAGATGGTAAAAACCGAGTTTACTTTTCATAA

Upstream 100 bases:

>100_bases
ATAAAAATGTCAGTTGTCTGTTAAAACTGACATTTTTGGAAGAAATAGCACAAAAATGTATGTAATATAGTCTGTTCACT
TCGTGTTAAAGAATTTATAC

Downstream 100 bases:

>100_bases
ACTCGGCCATTGGTTCGGGGAAATATGTGCGAAAAAATAAGGCTAGCTTACTTTTTCTAGCTCTTGATTTAGACGGGCAA
CGATAGGCTCTGATTTTTTA

Product: GGDEF domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MPKFNLKHIFLIPTLFLVLIVGFILNNHMNSVQRQVNREYDRIINSLQRSIKVIISLDYNISQLYKQNQGSFYNHNFEIK
KDSGLCVIRPSENLDAVMAEQDISVAEGRLDYSIAGKKDLCDPSSEVYEIASKKVSLAPVISFIHDYESYLHGIYFISKY
NYIISSPKEIAENLSQKTLDVIYSRPYWKNSMKNDSEKYITFTPPYTDAFFDGLEVLTFSTPIYYKGIFKGVLVIDLSVE
KLLRSSNEISQHIQLLNSDEYKRFEQYRFMQPVNLDFTDFTYFLYYKTSIKEELKGFLVHDSNSLILTLVMYILSLLSMF
YYQSRVSQKYYRDLAKQDPMTGLYNRRGFEMSLQDRVVKKYVGFAIYDIDDFKQINDVFGHDVGDEAIKYVARMLNKSVR
DSDIVSRFGGEEFVICINAESRNSLESVCERVRKSIQDSSGKVVKGGFTVSGGVTVIDSHQEFSFEHVIKKADALLYKAK
QDGKNRVYFS

Sequences:

>Translated_490_residues
MPKFNLKHIFLIPTLFLVLIVGFILNNHMNSVQRQVNREYDRIINSLQRSIKVIISLDYNISQLYKQNQGSFYNHNFEIK
KDSGLCVIRPSENLDAVMAEQDISVAEGRLDYSIAGKKDLCDPSSEVYEIASKKVSLAPVISFIHDYESYLHGIYFISKY
NYIISSPKEIAENLSQKTLDVIYSRPYWKNSMKNDSEKYITFTPPYTDAFFDGLEVLTFSTPIYYKGIFKGVLVIDLSVE
KLLRSSNEISQHIQLLNSDEYKRFEQYRFMQPVNLDFTDFTYFLYYKTSIKEELKGFLVHDSNSLILTLVMYILSLLSMF
YYQSRVSQKYYRDLAKQDPMTGLYNRRGFEMSLQDRVVKKYVGFAIYDIDDFKQINDVFGHDVGDEAIKYVARMLNKSVR
DSDIVSRFGGEEFVICINAESRNSLESVCERVRKSIQDSSGKVVKGGFTVSGGVTVIDSHQEFSFEHVIKKADALLYKAK
QDGKNRVYFS
>Mature_489_residues
PKFNLKHIFLIPTLFLVLIVGFILNNHMNSVQRQVNREYDRIINSLQRSIKVIISLDYNISQLYKQNQGSFYNHNFEIKK
DSGLCVIRPSENLDAVMAEQDISVAEGRLDYSIAGKKDLCDPSSEVYEIASKKVSLAPVISFIHDYESYLHGIYFISKYN
YIISSPKEIAENLSQKTLDVIYSRPYWKNSMKNDSEKYITFTPPYTDAFFDGLEVLTFSTPIYYKGIFKGVLVIDLSVEK
LLRSSNEISQHIQLLNSDEYKRFEQYRFMQPVNLDFTDFTYFLYYKTSIKEELKGFLVHDSNSLILTLVMYILSLLSMFY
YQSRVSQKYYRDLAKQDPMTGLYNRRGFEMSLQDRVVKKYVGFAIYDIDDFKQINDVFGHDVGDEAIKYVARMLNKSVRD
SDIVSRFGGEEFVICINAESRNSLESVCERVRKSIQDSSGKVVKGGFTVSGGVTVIDSHQEFSFEHVIKKADALLYKAKQ
DGKNRVYFS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=162, Percent_Identity=36.4197530864198, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787262, Length=181, Percent_Identity=30.3867403314917, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87081881, Length=163, Percent_Identity=38.6503067484663, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI145693134, Length=159, Percent_Identity=34.5911949685535, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI87082007, Length=216, Percent_Identity=31.0185185185185, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081974, Length=297, Percent_Identity=27.9461279461279, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788381, Length=175, Percent_Identity=30.8571428571429, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787816, Length=164, Percent_Identity=33.5365853658537, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788085, Length=161, Percent_Identity=32.9192546583851, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787802, Length=163, Percent_Identity=33.1288343558282, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787541, Length=170, Percent_Identity=28.2352941176471, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787056, Length=151, Percent_Identity=28.476821192053, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 56764; Mature: 56632

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKFNLKHIFLIPTLFLVLIVGFILNNHMNSVQRQVNREYDRIINSLQRSIKVIISLDYN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCC
ISQLYKQNQGSFYNHNFEIKKDSGLCVIRPSENLDAVMAEQDISVAEGRLDYSIAGKKDL
HHHHHHCCCCCEECCCEEEECCCCEEEECCCCCCCHHHHHCCCHHHCCCCCEEECCCCCC
CDPSSEVYEIASKKVSLAPVISFIHDYESYLHGIYFISKYNYIISSPKEIAENLSQKTLD
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHH
VIYSRPYWKNSMKNDSEKYITFTPPYTDAFFDGLEVLTFSTPIYYKGIFKGVLVIDLSVE
HHHCCCCCCCCCCCCCCCEEEECCCCHHHHHCCHHEEEECCCHHHHHHHCCEEEEEECHH
KLLRSSNEISQHIQLLNSDEYKRFEQYRFMQPVNLDFTDFTYFLYYKTSIKEELKGFLVH
HHHHCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEEHHHHHHHCCEEEE
DSNSLILTLVMYILSLLSMFYYQSRVSQKYYRDLAKQDPMTGLYNRRGFEMSLQDRVVKK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHHH
YVGFAIYDIDDFKQINDVFGHDVGDEAIKYVARMLNKSVRDSDIVSRFGGEEFVICINAE
HHCEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEECC
SRNSLESVCERVRKSIQDSSGKVVKGGFTVSGGVTVIDSHQEFSFEHVIKKADALLYKAK
CCCHHHHHHHHHHHHHCCCCCCEEECCEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHH
QDGKNRVYFS
CCCCCCCCCC
>Mature Secondary Structure 
PKFNLKHIFLIPTLFLVLIVGFILNNHMNSVQRQVNREYDRIINSLQRSIKVIISLDYN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCC
ISQLYKQNQGSFYNHNFEIKKDSGLCVIRPSENLDAVMAEQDISVAEGRLDYSIAGKKDL
HHHHHHCCCCCEECCCEEEECCCCEEEECCCCCCCHHHHHCCCHHHCCCCCEEECCCCCC
CDPSSEVYEIASKKVSLAPVISFIHDYESYLHGIYFISKYNYIISSPKEIAENLSQKTLD
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHH
VIYSRPYWKNSMKNDSEKYITFTPPYTDAFFDGLEVLTFSTPIYYKGIFKGVLVIDLSVE
HHHCCCCCCCCCCCCCCCEEEECCCCHHHHHCCHHEEEECCCHHHHHHHCCEEEEEECHH
KLLRSSNEISQHIQLLNSDEYKRFEQYRFMQPVNLDFTDFTYFLYYKTSIKEELKGFLVH
HHHHCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEEEEHHHHHHHCCEEEE
DSNSLILTLVMYILSLLSMFYYQSRVSQKYYRDLAKQDPMTGLYNRRGFEMSLQDRVVKK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCHHHHHHHH
YVGFAIYDIDDFKQINDVFGHDVGDEAIKYVARMLNKSVRDSDIVSRFGGEEFVICINAE
HHCEEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEECC
SRNSLESVCERVRKSIQDSSGKVVKGGFTVSGGVTVIDSHQEFSFEHVIKKADALLYKAK
CCCHHHHHHHHHHHHHCCCCCCEEECCEEEECCEEEEECCCCCCHHHHHHHHHHHHHHHH
QDGKNRVYFS
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]