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The map label for this gene is oppC [H]

Identifier: 59712202

GI number: 59712202

Start: 1788205

End: 1789107

Strand: Reverse

Name: oppC [H]

Synonym: VF_1595

Alternate gene names: 59712202

Gene position: 1789107-1788205 (Counterclockwise)

Preceding gene: 59712203

Following gene: 59712201

Centisome position: 61.75

GC content: 40.31

Gene sequence:

>903_bases
ATGTTAACGAAAAAAGAAAATTTAGAAGCGATTGAAAAATTCTCTGAAAGTTTGGAGATTGAGGGTCGCAGTCTATGGCA
AGACGCACGAATCCGCTTTATGCGAAACAAAGCGGCAATGATCAGTTTGTTTATTCTTACATTGATGACTTTGGCTGTAA
TTTTCCTGCCGATGTTCAGTCAATATGCTTATGATGATACGGATTGGTATGCACTACACCAAGGCCCAAGTATGGCGCAC
TTATTTGGAACGGACAGCTTAGGTCGTGATTTATTTGTTCGTACCTTAGTTGGCGGACGAATTTCATTGATGGTTGGTAT
TCTAGGTGCATTAGTTGCTGTACTAATTGGAACGCTTTACGGAGCAACATCAGGCTTTGTTGGTGGTAAAGTTGACCGAG
TAATGATGCGTTTTATTGAAATCTTATACGCTGTGCCTTTTATGTTTTTGGTTATCGTATTAGTAACATTTTTTGGGCGT
AATATCATTCTTATCTTTGTTGCTATTGGTGCAATTGCTTGGCTTGATATGGCTCGTATTGTTCGTGGTCAAACACTTAG
CTTACGTAGTAAAGAGTTTATTGAAGCAGCACACGTGTGCGGTGTGAGTAAGTGGGGCATCATCACTCGTCATATCGTAC
CAAACGTACTAGGTATTGTTGCCGTTTATTCAACATTACTTATCCCGAGTATGATCCTAACTGAATCTTTCTTATCTTTC
CTTGGTCTAGGTGTTCAAGAGCCGATGACTAGTTGGGGCGCCTTACTTCAAGAAGGTTCTCAAACTATGGAAGTGGCAAT
TTGGCAGTTAACTTTCCCAGCTTTATTTATGGTCGTTACCTTGTTCTGCTTTAACTATGTAGGTGATGGTTTACGTGATG
CGCTGGATCCAAAAGACAGATAA

Upstream 100 bases:

>100_bases
CCATTCTGATTGGTTTCCTATTTATCTTATTCAACGCAATTGTTGATGTATTACTAGCAATTATCGACCCGAAAATTCGT
TATTAATAGGGAATGGACGC

Downstream 100 bases:

>100_bases
TCCTCTGTGTGGACAGTTAATTATTAAACAAATTTGAGCAGGAAAGAATTATGAGTTTATTAGATGTAAAAGATCTGCGA
GTAGAGTTCACCACACAAGA

Product: oligopeptide transport system permease protein OppC

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MLTKKENLEAIEKFSESLEIEGRSLWQDARIRFMRNKAAMISLFILTLMTLAVIFLPMFSQYAYDDTDWYALHQGPSMAH
LFGTDSLGRDLFVRTLVGGRISLMVGILGALVAVLIGTLYGATSGFVGGKVDRVMMRFIEILYAVPFMFLVIVLVTFFGR
NIILIFVAIGAIAWLDMARIVRGQTLSLRSKEFIEAAHVCGVSKWGIITRHIVPNVLGIVAVYSTLLIPSMILTESFLSF
LGLGVQEPMTSWGALLQEGSQTMEVAIWQLTFPALFMVVTLFCFNYVGDGLRDALDPKDR

Sequences:

>Translated_300_residues
MLTKKENLEAIEKFSESLEIEGRSLWQDARIRFMRNKAAMISLFILTLMTLAVIFLPMFSQYAYDDTDWYALHQGPSMAH
LFGTDSLGRDLFVRTLVGGRISLMVGILGALVAVLIGTLYGATSGFVGGKVDRVMMRFIEILYAVPFMFLVIVLVTFFGR
NIILIFVAIGAIAWLDMARIVRGQTLSLRSKEFIEAAHVCGVSKWGIITRHIVPNVLGIVAVYSTLLIPSMILTESFLSF
LGLGVQEPMTSWGALLQEGSQTMEVAIWQLTFPALFMVVTLFCFNYVGDGLRDALDPKDR
>Mature_300_residues
MLTKKENLEAIEKFSESLEIEGRSLWQDARIRFMRNKAAMISLFILTLMTLAVIFLPMFSQYAYDDTDWYALHQGPSMAH
LFGTDSLGRDLFVRTLVGGRISLMVGILGALVAVLIGTLYGATSGFVGGKVDRVMMRFIEILYAVPFMFLVIVLVTFFGR
NIILIFVAIGAIAWLDMARIVRGQTLSLRSKEFIEAAHVCGVSKWGIITRHIVPNVLGIVAVYSTLLIPSMILTESFLSF
LGLGVQEPMTSWGALLQEGSQTMEVAIWQLTFPALFMVVTLFCFNYVGDGLRDALDPKDR

Specific function: Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787498, Length=302, Percent_Identity=69.205298013245, Blast_Score=394, Evalue=1e-111,
Organism=Escherichia coli, GI1787054, Length=277, Percent_Identity=39.7111913357401, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1787760, Length=257, Percent_Identity=37.3540856031128, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1789964, Length=272, Percent_Identity=35.6617647058824, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789889, Length=223, Percent_Identity=33.6322869955157, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788505, Length=223, Percent_Identity=33.6322869955157, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1787549, Length=279, Percent_Identity=26.5232974910394, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33441; Mature: 33441

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTKKENLEAIEKFSESLEIEGRSLWQDARIRFMRNKAAMISLFILTLMTLAVIFLPMFS
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QYAYDDTDWYALHQGPSMAHLFGTDSLGRDLFVRTLVGGRISLMVGILGALVAVLIGTLY
HHCCCCCCEEEEECCCCCHHECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
GATSGFVGGKVDRVMMRFIEILYAVPFMFLVIVLVTFFGRNIILIFVAIGAIAWLDMARI
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VRGQTLSLRSKEFIEAAHVCGVSKWGIITRHIVPNVLGIVAVYSTLLIPSMILTESFLSF
HCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLGVQEPMTSWGALLQEGSQTMEVAIWQLTFPALFMVVTLFCFNYVGDGLRDALDPKDR
HCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCC
>Mature Secondary Structure
MLTKKENLEAIEKFSESLEIEGRSLWQDARIRFMRNKAAMISLFILTLMTLAVIFLPMFS
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QYAYDDTDWYALHQGPSMAHLFGTDSLGRDLFVRTLVGGRISLMVGILGALVAVLIGTLY
HHCCCCCCEEEEECCCCCHHECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
GATSGFVGGKVDRVMMRFIEILYAVPFMFLVIVLVTFFGRNIILIFVAIGAIAWLDMARI
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VRGQTLSLRSKEFIEAAHVCGVSKWGIITRHIVPNVLGIVAVYSTLLIPSMILTESFLSF
HCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLGVQEPMTSWGALLQEGSQTMEVAIWQLTFPALFMVVTLFCFNYVGDGLRDALDPKDR
HCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]