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The map label for this gene is dsbE [H]

Identifier: 59712156

GI number: 59712156

Start: 1732565

End: 1733092

Strand: Reverse

Name: dsbE [H]

Synonym: VF_1549

Alternate gene names: 59712156

Gene position: 1733092-1732565 (Counterclockwise)

Preceding gene: 59712157

Following gene: 59712155

Centisome position: 59.81

GC content: 38.07

Gene sequence:

>528_bases
ATGAAGCAAATAGCTAAGGTTCTCACTGCTATCATTTTGTGTATTGCAGTTTTTTTTGTGTTACTAAGTGGTTTAGAAAC
CAAGGAATCCTCAGGTTCTACAGCAATGGTGGGGGAAACGGTTCCTGCTTTTAAATTATCAGATGTCACCGACGCCTCTA
CGTATTTAACGGAATCTATTTTTCATAATGATTCACTTACCTTGCTTAATGTGTGGGCGGCATGGTGTGGAATATGCAAA
ACAGAGCATCAATTTTTACATCAACTTAAAGAGCAAGGGATACCAATTATTGGTTTAGATTACCGTGATAATAGAAGTGC
AGCAAAACAGGTATTAGAGCAAACTGGTAATCCATATCAAGCTGTTCTTTATGATCCTCAAGGGATTTTAGCCATGGATT
TAGGGGTTTATGGAACGCCGACAACCTTTGTTATTGATCAACATGGCAAGATATTACATCGATTTACAGGCGCGTTGAAT
GAAGAAAAGTGGCAACGTGAATTTGCCGATTTTTTTGAGGGAAAATAA

Upstream 100 bases:

>100_bases
GATTGCAATATAAAGCGTACGTGAGGTGGATTTGGTTTGGCTCATTGTTAATGTGTGTTGGAGGGGTATTCGCTATGGTT
AAAAGAAAGAGAAAAACAGC

Downstream 100 bases:

>100_bases
TGAAGCATTCTTTTAAATCATTACTGTATTTATTCTGTTTATTGAGTATGTTTTCAGTCAACGCTGCATTAGATAATAGT
AATGACTTATTCGTTTCTGC

Product: thiol:disulfide interchange protein TlpA

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CcmG [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MKQIAKVLTAIILCIAVFFVLLSGLETKESSGSTAMVGETVPAFKLSDVTDASTYLTESIFHNDSLTLLNVWAAWCGICK
TEHQFLHQLKEQGIPIIGLDYRDNRSAAKQVLEQTGNPYQAVLYDPQGILAMDLGVYGTPTTFVIDQHGKILHRFTGALN
EEKWQREFADFFEGK

Sequences:

>Translated_175_residues
MKQIAKVLTAIILCIAVFFVLLSGLETKESSGSTAMVGETVPAFKLSDVTDASTYLTESIFHNDSLTLLNVWAAWCGICK
TEHQFLHQLKEQGIPIIGLDYRDNRSAAKQVLEQTGNPYQAVLYDPQGILAMDLGVYGTPTTFVIDQHGKILHRFTGALN
EEKWQREFADFFEGK
>Mature_175_residues
MKQIAKVLTAIILCIAVFFVLLSGLETKESSGSTAMVGETVPAFKLSDVTDASTYLTESIFHNDSLTLLNVWAAWCGICK
TEHQFLHQLKEQGIPIIGLDYRDNRSAAKQVLEQTGNPYQAVLYDPQGILAMDLGVYGTPTTFVIDQHGKILHRFTGALN
EEKWQREFADFFEGK

Specific function: Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=173, Percent_Identity=37.5722543352601, Blast_Score=139, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 19488; Mature: 19488

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIAKVLTAIILCIAVFFVLLSGLETKESSGSTAMVGETVPAFKLSDVTDASTYLTESI
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEECCCCCHHHHHHHHHH
FHNDSLTLLNVWAAWCGICKTEHQFLHQLKEQGIPIIGLDYRDNRSAAKQVLEQTGNPYQ
HCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCEE
AVLYDPQGILAMDLGVYGTPTTFVIDQHGKILHRFTGALNEEKWQREFADFFEGK
EEEECCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKQIAKVLTAIILCIAVFFVLLSGLETKESSGSTAMVGETVPAFKLSDVTDASTYLTESI
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCEECCCCCHHHHHHHHHH
FHNDSLTLLNVWAAWCGICKTEHQFLHQLKEQGIPIIGLDYRDNRSAAKQVLEQTGNPYQ
HCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCEE
AVLYDPQGILAMDLGVYGTPTTFVIDQHGKILHRFTGALNEEKWQREFADFFEGK
EEEECCCCEEEEECCCCCCCEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]